Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Josh has a large knot on his head resulting from a car crash from 18 years ago; Brittney is covered in mysterious bumps; TJ has a hard, curious lump protruding from his side; Luis has a bump on his shoulder and his daughters fear it's dangerous.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Leonard has an alarming bump hanging off of his arm that looks like it's breaking through the skin; Brandon has several lumps on his head that make him fearful for his life; Jess gets a noticeable lump on her butt after falling down the stairs.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Taylore is a beautiful young woman who has unsightly elf-like bumps on her ears; Jose never goes out because of the baseball-sized lump on his head; Ken is covered in painful bumps that make it difficult to do everyday things.

A woman is impaled on an iron spike; a man spears his friend on a fishing trip; an elderly gardener's shears are lodged in his eye.

A man is impaled on a fence post; a farmer has an object lodged in his brain; a woman is skewered on a hooked pole when she feeds the birds.

A woman gets a Christmas tree imbedded in her neck; a boy out fishing almost chokes on a barb; a man is filled with enough air to fill 1000 balloons; learn how they survived.

A woman gives birth prematurely during Hurricane Sandy; an Army soldier coaches his wife's delivery from Afghanistan; a baby delivered in a shopping mall parking lot.

An emergency birth interrupts a wedding; a woman delivers after crashing her car; a baby with a life-threatening condition is born prematurely.

A baby is born twice; a woman in labor is torn apart by a tornado; a wife gives birth at home.

Horseback-riding accident; broken wrist; crash victims.

Cardiac arrest after a DWI crash; ATV accident; drug overdose.

Brain death; life support; organ donation; transplants.

Shooting victim; teen is severely injured.

Stephanie and her mom Darcy lost a combined weight of 320 lbs.; BJ overcame drug and food addiction to lose 350 lbs. and his body is now covered with excess skin.

Antonia overcame her food addiction to lose 190lbs, but the extra skin is keeping her from feeling confident and sexy; Natasha lost almost 300lbs after gastric bypass surgery, but now struggles with carrying a lot of saggy excess skin.

Linda is hoping skin removal surgery will give her the self-esteem she needs to be an amazing role model to her daughters; Angel hates her extra skin because it's turning her into an introvert around her family.

Shantel needs to get rid of her excess skin to gain the confidence she needs to set a positive example for her daughter; Hope has an obsession with weight loss that could make her too unhealthy to have skin removal surgery.

When faced with treating a man whose cheek is about to pop due to a 4lb tumor, Dr. Panossian worries it could become a deadly situation; a woman whose lower lip won't stop growing turns to Dr. Rovelo for help.

Dr. Roostaeian wants to help a young woman living with the largest birthmark he's ever seen, however, surgery could be life-threatening; after being hit by a drunk driver, Dr. Rovelo's patient hasn't been able to close his mouth.

Dr. Panossian and Dr. Rovelo join forces to remove a tumor that has wrapped around a man's head; a woman hopes Dr. Rovelo can remove her mouthy birthmark.

Dr. Roostaeian and Dr. Panossian encounter one of the challenging cases of their career when they meet a young man with two faces; Dr. Rovelo treats one of the first monkey pox cases in Los Angeles.

When faced with treating a man whose cheek is about to pop due to a 4lb tumor, Dr. Panossian worries it could become a deadly situation; a woman whose lower lip won't stop growing turns to Dr. Rovelo for help.

Dr. Roostaeian wants to help a young woman living with the largest birthmark he's ever seen, however, surgery could be life-threatening; after being hit by a drunk driver, Dr. Rovelo's patient hasn't been able to close his mouth.

Dr. Panossian and Dr. Rovelo join forces to remove a tumor that has wrapped around a man's head; a woman hopes Dr. Rovelo can remove her mouthy birthmark.

Dr. Roostaeian and Dr. Panossian encounter one of the challenging cases of their career when they meet a young man with two faces; Dr. Rovelo treats one of the first monkey pox cases in Los Angeles.

Linda is hoping skin removal surgery will give her the self-esteem she needs to be an amazing role model to her daughters; Angel hates her extra skin because it's turning her into an introvert around her family.

Shantel needs to get rid of her excess skin to gain the confidence she needs to set a positive example for her daughter; Hope has an obsession with weight loss that could make her too unhealthy to have skin removal surgery.

Dr. Nowzaradan is worried Lupe's emotional issues are blocking her weight loss journey since she's shed over 300-lbs but still can't walk; when Ashley is struck with sudden paralysis, her own emotional stability is thrown into peril.

Olivia suffers an unexpected loss; James strives to reach his goal of skin surgery and have a fulfilling relationship.

Zsalynn struggles between fighting her weight and fighting for her marriage; Christina releases the negativity in her life and finally begins to live.

Gastric surgery freed Brittani from her housebound life, but to achieve her ideal body she'll have to endure two more painful surgeries; Sean's super-obesity nearly killed him.

Surgery enables Teretha to return to family in Detroit, but it soon threatens to undo all her progress; Chad is back on the road, but his old diet is a risk.

After losing 250lbs, Nikki is on her way to skin surgery, but when a close friend dies from weight loss surgery, Nikki's progress is derailed by fears.

Devastated by the sudden loss of her son, Dottie's weight loss journey is in danger of going off track; June embarks on a plan to win approval for skin surgery; Melissa, Jessica and Matt prepare for skin removal surgery.

Charity's daughter is becoming dangerously obese; devastated by the death of her husband Elroy, Milla must find a way to finally qualify for gastric bypass; check-in with individuals who have undergone skin removal surgery.

Once 800lbs, housebound and alone, Joe is now engaged and planning a wedding; after losing over 300lbs, Pauline is on the verge of independence if only she can qualify for the skin surgery she needs so badly.

Surgery enabled Laura's independence, but the complications nearly killed her, and she's terrified about the next skin surgery; Chay revealed to her family she was transgender, but living life as an overweight woman.

Once 800lbs, housebound and alone, Joe is now engaged and planning a wedding; after losing over 300lbs, Pauline is on the verge of independence if only she can qualify for the skin surgery she needs so badly.

Surgery enabled Laura's independence, but the complications nearly killed her, and she's terrified about the next skin surgery; Chay revealed to her family she was transgender, but living life as an overweight woman.

Charity's daughter is becoming dangerously obese; devastated by the death of her husband Elroy, Milla must find a way to finally qualify for gastric bypass; check-in with individuals who have undergone skin removal surgery.

For 23 years, Leneatha has worked as a pharmacy tech at a local hospital; now, she has a young daughter to support, but she's so big that it's hard to move; if Dr Now can't help her stop eating, losing her job could be the least of her worries.

Christina has not left her house in two years due to her size; she has eaten herself into a state that will soon kill her if she does not change.

Paula has built a wall around herself to push people away; when she suddenly loses a loved one she can no longer ignore the threat of losing her own life.

At nearly 1,000 pounds, Samantha is dangerously close to dying; to make matters worse, she's paid to eat by making videos online; if Samantha doesn't overcome her toxic relationship with food, she worries she will leave her daughter motherless.

Twenty years after her father died as the result of a botched weight-loss surgery, Carrie is on the brink of eating herself to death; she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband, Chris.

Thederick has become housebound from eating and only goes outside to greet the ice cream man; after a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.

Cindy is resistant to change and spends years creating a world that makes her feel safe; when her friend notices Cindy's health declining rapidly due to her size, she pushes Cindy to move to Houston and see Dr. Now.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Kenae' is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae' turns to food to fill the void.

Krystal begins overeating to shield herself with a protective layer of obesity after suffering years of abuse; once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.

Kenae' is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae' turns to food to fill the void.

Krystal begins overeating to shield herself with a protective layer of obesity after suffering years of abuse; once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

A gunman opens fire outside a strip club; a street performer's magic trick goes horribly wrong; BMX superstar T.J. Lavin's routine jump has a shocking outcome.

A maintenance worker falls from an iconic hotel sign; a rat bite has horrifying implications for its trainer and a plane crashes on a residential street.

A shootout leaves a police officer clinging to life; a cowboy and cupid help a she-devil in distress; a zip-line guide falls 80 feet to the canyon floor.

Eight women cope with their incarceration in Gwinnett County Jail; one woman prepares for her release.

Nine women try to cope with their incarceration; a woman awaits trial for five years.

A young mother faces the idea of seeing her son through visitation glass; an inmate promises not to return but finds herself back in jail; a desperate inmate only needs a small amount of money to get released.

A current inmate learns that her son has died in a car crash; an inmate's first Mother's Day behind bars; female inmate almost nine months pregnant.

The emergency room at Highland Hospital in Oakland, Calif., treats a large population of people struggling with poverty and substance abuse.

Doctors at the Good Samaritan Regional Medical Center treat a teenager who collided with a tractor-trailer; a stabbing victim.

Denver Health Medical Center's trauma unit, which handled the Columbine High School shooting victims, regularly treats accident victims.

How Minnesota's oldest emergency room at the Hennepin County Medical Center has kept up with the times.

A successful businesswoman suddenly seems to become possessed by demons; a young college student battles monstrous pain when she grows fingernails out of her hair follicles.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

Charmaine from Trinidad suffers from one of the most extreme cases of neurofibromatosis ever recorded; tumors cover every inch of her body and obstruct her ability to breathe and swallow; without surgery, these growing tumors threaten her life.

Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist; as the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.

Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor; Amy has let the tumor on her back grow for more than 17 years; after finally making the decision to remove it, she learns that now it might be too late.

A massive tumor on Tim's neck continues to grow at an alarming rate, but doctors fear that removing it could leave him paralyzed.

Charmaine from Trinidad suffers from one of the most extreme cases of neurofibromatosis ever recorded; tumors cover every inch of her body and obstruct her ability to breathe and swallow; without surgery, these growing tumors threaten her life.

Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist; as the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.

Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor; Amy has let the tumor on her back grow for more than 17 years; after finally making the decision to remove it, she learns that now it might be too late.

A massive tumor on Tim's neck continues to grow at an alarming rate, but doctors fear that removing it could leave him paralyzed.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

Getting too hot can be fatal for twins Andrew and Brandon, who meet Josh, a fellow sufferer of Ectodermal Dysplasia.

Tiffany and Yajaira have Jarcho Levin Syndrome, which malformed their ribs and spines during infancy.

Born with Goldenhar Syndrome, Austin and Elena have been bullied for looking different, and feel isolated from other kids.

A young boy struggles to breathe.

A child's brain contains a strange mass; doctors fear the worst until a radiologist makes an observation.

A man experiences vomiting, heart palpitations, weakness and general malaise.

After Thomas Hicks sold over 200 babies illegally in the 1950s and 1960s, Jane Blasio works to reunite the stolen babies with biological families while trying to unearth secrets about Hicks himself.

Jane discovers a suspicious pattern of babies with extremely low birth weights coming out of the clinic; Chris finds out that Dr. Hicks may have hidden birth records in his mausoleum; Diane hopes to meet her biological father.

Jane and Lisa meet the first Hicks baby, Stephen Dilbeck; Chris and Sallie open the mausoleum in search of birth records rumored to be inside as they work on getting approval of an exhumation.

A woman's world was shaken when she discovered she was adopted at 25, and goes onto learn more dramatic revelations; a mother is in a race against time to find her son who she placed for adoption 46 years ago.

A woman searches for her beloved sister who she tried to adopt herself years ago; after a life of longing, a couple is desperate to find the son they placed for adoption fifty years ago when they were teens.

A man searches for his birth mother, whose disappearance when he was 5 years old has haunted him for his entire life; a woman hoping to meet a member of her biological family faces certain realities about her true past.

A woman searches for her brother, hoping to fulfill a promise she made to her late mother, and discovers a 40-year-old secret about her parents' past; a woman consumed by a lifelong search for her mom finds hope with a new DNA connection.

A man seeking redemption from his troubled past longs to reunite with the grown son he only got to hold for a few minutes; 46 years after placing her daughter up for adoption, a woman still carries the feeling of guilt for being an unwed mother.

Phyllis and Patty aren't just identical twins, they are identical hoarders as well.

Lalie and her children suffer from mold, mice and flea infestations due to their upstairs neighbor and landlord, Denise, who is a massive hoarder.

Beverly's clutter has filled up her entire home and her three beloved dogs have helped make the space completely unlivable.

Terry and Bill seem to be the perfect couple; the murder of her daughter has led Nancy to hoard.

Phyllis and Patty aren't just identical twins, they are identical hoarders as well.

Lalie and her children suffer from mold, mice and flea infestations due to their upstairs neighbor and landlord, Denise, who is a massive hoarder.

Beverly's clutter has filled up her entire home and her three beloved dogs have helped make the space completely unlivable.

Terry and Bill seem to be the perfect couple; the murder of her daughter has led Nancy to hoard.

A woman searches for her brother, hoping to fulfill a promise she made to her late mother, and discovers a 40-year-old secret about her parents' past; a woman consumed by a lifelong search for her mom finds hope with a new DNA connection.

A man seeking redemption from his troubled past longs to reunite with the grown son he only got to hold for a few minutes; 46 years after placing her daughter up for adoption, a woman still carries the feeling of guilt for being an unwed mother.

Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10. While learning to cook for his family, he began comfort-eating. Now to avoid eating himself to death, Isaac must learn to take care of himself for a change.

James comes from a long line of family obesity; he is determined not to die as his sister and father did; he hopes to get gastric bypass and even start dating again.

A mother of two who is too ashamed of her size to be seen with her children; she is committed to regaining her confidence and being a proud mother.

A lifetime of abuse has left Michael anxious and afraid to leave the house; with the help of his devoted wife, he must follow Dr. Now's program to keep from eating himself to death.

Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden; Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live.

Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can't get through to her, the only thing that might help her break the cycle is a once-in-a-lifetime turn of events.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

Having her daughters help bathe her is not how Chrystal pictured parenting but she is so large that there's no other option; Chrystal wants Dr. Now's help but she didn't know that bringing her childhood trauma to light would be part of the deal.

Ryan moved to Montana to keep himself from going down a dark path of drug addiction but his new path may be no less lethal than the last if he can't find a way to curb his eating habits before they kill him.

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

Ryan moved to Montana to keep himself from going down a dark path of drug addiction but his new path may be no less lethal than the last if he can't find a way to curb his eating habits before they kill him.

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

Having her daughters help bathe her is not how Chrystal pictured parenting but she is so large that there's no other option; Chrystal wants Dr. Now's help but she didn't know that bringing her childhood trauma to light would be part of the deal.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Tony has large growths on his nose that impair his breathing; Kevin has a bump in his jawline that is a lady deterrent; Marie has an unsightly lump on her forehead that makes her a hermit; Tommy's leg bump makes it difficult for him to work.

Gerard has nearly a hundred lumps varying in size all over his body; Gina has bloody lesions all over; Eric has a large bump on his head that he calls his on and off button.

Traci's confidence has been destroyed after years of bullying from the bumps on her face; Ravon has a unique dangling growth on his leg; David has a large lump.

David is back to see Dr. Lee after she spots a suspicious growth under his eye; Nicole is depressed because of the bumps all over her neck; Steve has a noticeable lump on his forehead; Allen has a growth on his biceps but is terrified of doctors.

Tim has a massive growth on his back that affects his ability to work and socialize; Daniel has debilitating psoriasis that covers most of his body; Gloriana and Yolanda are a mother and daughter duo who have bonded over their bumps.

Inoke has a huge, possibly life-threatening bulge on his shoulder; Delano returns with his back lump after Dr. Lee removed a liter of fluid from it; Reed has hundreds of bumps on his chest that burst and leave nasty scars.

With pandemic safety protocols in place, Dr. Lee reopens her office; Monica has a large birthmark growing on the side of her face; Jackie has a melon-sized lump on the back of her shoulder; Reginald has large, rare growths on the back of his head.

Dr. Lee tries to provide the help Reginald needs to remove the large, rare growths on the back of his head; Che'Re has a prominent bump on her face that has put her in a dark place; Juan has several painful boils on the back of his neck.

Dennis has several giant growths on the back of his head; Juan has a rare condition he hopes Dr. Lee will understand; Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps.

Audrey pops the painful bumps that cover her body so she can feel relief; Felicia has a peculiar-looking dark growth on her forehead; Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat.

John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.

Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.

Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.

Audrey pops the painful bumps that cover her body so she can feel relief; Felicia has a peculiar-looking dark growth on her forehead; Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat.

John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.

Dr. Vincent performs a delicate surgery when she treats a toddler born with 12 toes; Dr. Schaeffer meets a nudist with funky feet; things get tense during a foot reconstruction procedure when the patient wakes up in the middle of surgery.

After a horrific car accident as a child, Heather's ankle was rebuilt from parts of her body; now it's up to Dr. Vincent to help her walk again.

Dr. Vincent tries to save a man's enormous toe; Dr. Schaeffer has his hands full treating a little boy with big demands; a man with incredibly long toes.

Dr. Schaeffer has to straighten a woman's serpentine foot to reset her life, as Dr. Vincent gets a drummer's foot back on the beat.

Dr. Ebonie's skills are tested as she attempts to diagnose a patient with feet covered in huge, wart-like masses; Dr. Brad is confronted with a mystery case that could be related to the elephant man as well as a patient with paper-thin skin.

A woman starts growing uncontrollably.

A woman suffers crippling sinus pains.

A young man has strange growths; toddler rapidly gains weight.

A baby is born with a series of defects; deadly sore throat.

A Halloween zombie with a problem below the belt mystifies doctors; two unconscious men are involved in an accident, a doctor makes a mistake that amazingly explains a patient's condition.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change; a pregnant woman's life-threatening symptoms need urgent treatment.

A student's head is impaled by a trophy deer's antlers; a semi-conscious car crash victim; a woman with an allergic reaction.

A man injured in a medieval role playing battle has a sword impaled in his head; a critically ill patient is so afraid of germs he won't allow doctors to treat him; two patients with the same life-threatening symptoms.

A doctor treats three gunshot victims who claim be innocent bystanders; a doctor must perform emergency brain surgery on his first day; a bride-to-be suddenly slips into a diabetic coma.

Sean's nightmare keeps coming true, he can't stop pooping himself on stage; Tired of dealing with explosive bowels, Sean asks Dr. Hodges for help; Latoya wants to spend time with her kids again which means the 10 pound mass between her legs needs to go.

AliceJean's botched lap band removal left her with six belly buttons that form a golf course on her stomach; Simone seeks help for her uncontrollable vomiting.

After a botched lap band surgery, Christina has been blending her meals for over a decade; Dr. Caplin assists a patient whose tummy tuck has left her with a butt crack for a stomach.

With bonus scenes; James has a large, squishy forehead lump; Tanisha has an arm growth and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison.

Sean's nightmare keeps coming true, he can't stop pooping himself on stage; Tired of dealing with explosive bowels, Sean asks Dr. Hodges for help; Latoya wants to spend time with her kids again which means the 10 pound mass between her legs needs to go.

AliceJean's botched lap band removal left her with six belly buttons that form a golf course on her stomach; Simone seeks help for her uncontrollable vomiting.

After a botched lap band surgery, Christina has been blending her meals for over a decade; Dr. Caplin assists a patient whose tummy tuck has left her with a butt crack for a stomach.

With bonus scenes; James has a large, squishy forehead lump; Tanisha has an arm growth and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison.

A man injured in a medieval role playing battle has a sword impaled in his head; a critically ill patient is so afraid of germs he won't allow doctors to treat him; two patients with the same life-threatening symptoms.

A doctor treats three gunshot victims who claim be innocent bystanders; a doctor must perform emergency brain surgery on his first day; a bride-to-be suddenly slips into a diabetic coma.

A number of challenges seem to have cornered Betti Jo and her husband; Susan encounters a serious problem that can throw everything off track.

Chuck's second year of weight loss and a new relationship; Paula struggles with juggling many responsibilities along with her weight-loss.

Penny returns to Maryland believing she can lose weight; Tara continues to lose weight and is dating for the first time.

Over 11 years, Melissa has lost 500 pounds and saw her weight drop to 137 pounds; now facing marital problems, three pregnancies, and life as a single mom, Melissa is struggling with a 150-pound weight gain and finds herself at a crossroads.

Steven Assanti weighs nearly 800 pounds and his brother Justin almost 600 pounds, and although they can't stand each other, their father packs up the family to travel across the country and seek help.

After successful sleeve gastrectomy procedures, the Dreier twins collectively lose more than 400 pounds and work toward skin surgeries when a major life event disrupts their world and threatens their progress.

Erica must return to California to continue her weight-loss journey, but she fears past emotional trauma will derail her progress.

Ashley lost over 200 lbs. in Houston, but a family of enablers threatens her progress; Diana has shed 300 lbs., but knee damage may cause her to regain weight.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Ashley hits an emotional wall and is desperate for skin surgery, but she's not losing any weight; after being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Ashley hits an emotional wall and is desperate for skin surgery, but she's not losing any weight; after being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

Ashley lost over 200 lbs. in Houston, but a family of enablers threatens her progress; Diana has shed 300 lbs., but knee damage may cause her to regain weight.

When Nathan's weight gets in the way of his job as a drama teacher, it's a wake-up call for him; changing his life might mean a falling out with his wife, Amber, who is also overweight, unless she can lose, too.

Penny has been bedridden for four years and moves to Texas to have gastric bypass; her unwillingness to make lifestyle changes could mean failure.

Chuck weighs almost 700 pounds; he has had to downsize his business and his wife feels like a single-parent who is ready to leave him.

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky; Lacey's weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

For Julian and his wife, Irma, it was love at first sight; in order to grow old together, Julian will have to overcome the food addiction that made him more than 800 pounds.

Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now's help with a second weight-loss surgery.

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.