Ronen's mysterious lump above his knee is one of the largest Dr. Lee has ever seen; Amber suffers from a debilitating skin disease that no one understands; Sandy has a neck lump she calls Tommy; Kristy's eyelid cyst is ruining her life.

Don's psoriasis has completely taken over his body; Jeff has a large growth on his spine; Sara has an extra set of breasts and nipples.

Angelina has a huge chest lump under her left breast; Delano has a football-sized mass on his back.

Melissa tries to cover a huge lipoma with a sweatshirt for years; Tyler's fear of cancer keep him from having his huge head lumps diagnosed; Tahj is covered in painful boils; Amber has ear keloids that take control of her life.

Ronen's mysterious lump above his knee is one of the largest Dr. Lee has ever seen; Amber suffers from a debilitating skin disease that no one understands; Sandy has a neck lump she calls Tommy; Kristy's eyelid cyst is ruining her life.

Jess is a widower looking for love who is stuck with a giant bump on his neck; Cherish developed a leopard-print face during pregnancy; former NFL defensive tackle Marcell Dareus hopes Dr. Lee can tackle his forehead lipoma.

Brent has a tricep bump potentially intertwined in his muscle; Jeb loves the beach but refuses to go because of the massive number of blackheads, pimples, and cysts all over his body; Wanda's mysterious mark that caves in her side.

Dr. Ebonie and Dr. Brad treat a woman who has a foot she says is cursed; a man who has an extraterrestrial on his toe; a woman who has a very cranky callus.

A woman with growths like permanent stilettos; a man with terribly twisted toes; a woman with feet that look like stones.

Summer has arrived; Doctors Ebonie, Brad and Sarah help patients prepare for summer as they deal with unsightly toenails, catastrophic calluses and a foot that leaves them completely frazzled.

Chiropractor Dr. Colón treats Liana, a cane-bound woman suffering from involuntary tremors; Sarah's obsession with corsets causes her migraines; Amy, a little person, can no longer walk on her own; Brenda has uncontrollable gas.

Dr. Colón helps a woman who cannot keep her joints in place; a new mother suffers from a tragic boat accident; a bodybuilding leukemia survivor; a constipated baby.

Dr. ColÃ3n faces more chiropractic challenges when she treats a woman with CMT who hopes to stand at her daughter's wedding, a big breasted woman with extreme neck pain, and the show's sound man, who was born with cerebral palsy and an uneven body.

A mother tries to protect her children from their father's hoard; an artist chooses frog, penguins and banana peels over her boyfriend.

Maggie's piles of collections is putting her son's life at risk; Bob's passion for swimming pool parts is pushing his family to the brink.

Traci is pregnant and desperate to move back home, but it's filled floor to ceiling with her mother's stuff.

Kathleen discovers a hoard of mice living in her kitchen; spending the night in a hoard might be the end of a marriage before it even begins.

Medical responders were not able to get in Renee's front door after she had fallen unconscious in her home.

Rick tries to salvage his cluttered home that was nearly destroyed in a house fire; Linda must get her house up to code in 60 days or she will be on the streets.

A man seeks to repair his face after being mauled by a tiger; an 11-year-old undergoes fire treatment to lose weight; a boy living with tissue paper skin; a man with a hole in his face search for cures; a model embraces her hairy birthmarks.

A girl lives with ants in her head; a man undergoes surgery to remove his 132-lb tumor; a woman with a large facial tumor contemplates a life-changing surgery.

Kinah's addiction to eating toilet paper threatens her health, and her relationships are also on the line; Nathaniel has taken his love of cars to the extreme; Lisa eats cat hair -- and she just cannot get enough.

Nick and Aubrey's addiction to drinking urine has Nick's mom extremely concerned; Karmello's life has gained new meaning since her addiction to illegal butt injections; Lori's addiction to sleeping with her blow dryer might be affecting someone else.

Tyler's addiction to smelling tuna is getting in the way of finding love; Lacey's addiction to plastic surgery and her cup size has grown; after mourning the loss of her record-setting fingernails, Ayanna still has an addiction.

Brittany's addiction to eating car seat foam forces her family to intervene; Lauren has put her addiction to bodybuilding behind her but has found a new obsession; Asha's addiction to her long locks remains strong, but her health remains in jeopardy.

Kinah's addiction to eating toilet paper threatens her health, and her relationships are also on the line; Nathaniel has taken his love of cars to the extreme; Lisa eats cat hair -- and she just cannot get enough.

Nick and Aubrey's addiction to drinking urine has Nick's mom extremely concerned; Karmello's life has gained new meaning since her addiction to illegal butt injections; Lori's addiction to sleeping with her blow dryer might be affecting someone else.

Tyler's addiction to smelling tuna is getting in the way of finding love; Lacey's addiction to plastic surgery and her cup size has grown; after mourning the loss of her record-setting fingernails, Ayanna still has an addiction.

Brittany's addiction to eating car seat foam forces her family to intervene; Lauren has put her addiction to bodybuilding behind her but has found a new obsession; Asha's addiction to her long locks remains strong, but her health remains in jeopardy.

A man seeks to repair his face after being mauled by a tiger; an 11-year-old undergoes fire treatment to lose weight; a boy living with tissue paper skin; a man with a hole in his face search for cures; a model embraces her hairy birthmarks.

A girl lives with ants in her head; a man undergoes surgery to remove his 132-lb tumor; a woman with a large facial tumor contemplates a life-changing surgery.

Krystal begins overeating to shield herself with a protective layer of obesity after suffering years of abuse; once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.

A woman battles severe depression and has not left her Chicago basement in two years; the hope of having a life-changing surgery.

Penny has been bedridden for four years and moves to Texas to have gastric bypass; her unwillingness to make lifestyle changes could mean failure.

Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.

Dr. Nowzaradan is worried Lupe's emotional issues are blocking her weight loss journey since she's shed over 300-lbs but still can't walk; when Ashley is struck with sudden paralysis, her own emotional stability is thrown into peril.

Brittani has lost over 400 pounds in two years, so she and husband Bill think about expanding their family; Lupe has struggled since surgery, but, having left her husband, may finally start to make the permanent changes she needs.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food; only the help of Dr. Now's weight-loss program can restore his hopes of living a happy, productive life.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Maja cannot be allowed to undergo bariatric surgery unless she quits emotional eating. However, it seems like Justin may end up making Dr. Now proud.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Maja cannot be allowed to undergo bariatric surgery unless she quits emotional eating. However, it seems like Justin may end up making Dr. Now proud.

A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food; only the help of Dr. Now's weight-loss program can restore his hopes of living a happy, productive life.

Mercedes, who has severe lymphedema, must overcome trauma to lose weight.

James comes from a long line of family obesity; he is determined not to die as his sister and father did; he hopes to get gastric bypass and even start dating again.

Paula has built a wall around herself to push people away; when she suddenly loses a loved one she can no longer ignore the threat of losing her own life.

Patrick's weight has never been a bother, but now he's so big that it's getting in the way of his relationship with his daughter; if he wants to see her graduate high school, he'll have to reverse course.

Former plus-size model and advocate Renee realizes the mortal mistakes she has made as her weight swells to 600 pounds and her health crumbles.

After a difficult childhood with an abusive stepfather and drug-addicted mother, Sarah is fighting for her life at only 24 years old.

In the fourth year of his weight-loss journey, Sean struggles to get past the loss of his mother and live on his own; Dr. Now intervenes to control Sean's eating for a time.

Seana is 23 and nearly 700 lbs, living at her mom's house, depressed and anxious, her weight-gain threatening to take her last breath; Dr. Now can give her the tools she needs to live, but until she chooses life, no one can save Seana but herself.

A lifetime of abuse has left Michael anxious and afraid to leave the house; with the help of his devoted wife, he must follow Dr. Now's program to keep from eating himself to death.

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

A lifetime of abuse has left Michael anxious and afraid to leave the house; with the help of his devoted wife, he must follow Dr. Now's program to keep from eating himself to death.

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

Seana is 23 and nearly 700 lbs, living at her mom's house, depressed and anxious, her weight-gain threatening to take her last breath; Dr. Now can give her the tools she needs to live, but until she chooses life, no one can save Seana but herself.

A woman searches for her brother, hoping to fulfill a promise she made to her late mother, and discovers a 40-year-old secret about her parents' past; a woman consumed by a lifelong search for her mom finds hope with a new DNA connection.

A man seeking redemption from his troubled past longs to reunite with the grown son he only got to hold for a few minutes; 46 years after placing her daughter up for adoption, a woman still carries the feeling of guilt for being an unwed mother.

A couple longs to find the daughter they had as young teens; a woman learns her birth was a secret; taking place live, a bride and groom reveal a momentous surprise to their wedding guests and someone gets reunited with a long-lost family member.

A woman whose daughter perished in a car accident hopes to find comfort in locating her granddaughter, who was placed for adoption 26 years ago; a woman yearning to meet her birth mother is stunned by an unlikely figure in the search.

An obese woman is accused of murder after being charged with crushing her nephew to death.

Since her acquittal of her nephew's murder, a woman has taken steps to save her own life in hopes to adopt her nieces and nephew; the challenges of losing a large amount of weight.

A woman cracks under the pressure of jail life; a woman who is pregnant finds herself in the middle of a jailhouse brawl; a heroin addict chooses to stay in jail.

A woman works through the fallout of her addiction; a woman involved in a drug cartel seeks redemption; a pregnant woman prays; a woman attempts to smuggle contraband.

A jail newcomer gets more than she bargains for; a young mother's release is postponed; the tenth trip for a heroin addict.

A crack-addicted pregnant prostitute finds safe haven in jail; two best friends share a heroin addiction; a prostitute struggles to overcome her past.

A woman is arrested for smuggling drug paraphernalia into court; two heroin addicts turn to each other for support; a life of prostitution supports a woman's drug habit.

A woman turns to drugs to numb the pain of her divorce; a crack addict attempts to head-butt an officer; a dental office assistant is arrested for stealing.

Extreme hoarder Floyd must clear his hoard or risk losing his three year old son.

Donny has been to jail twice because of his hoard; Joyce finds comfort in her doll collection, while others see it as creepy.

It takes less than a week for 16-year old Haley to fill a bedroom with stuff; her parents hope that a visit with an extreme hoarder will scare their daughter straight.

A former ventriloquist turns her career into an obsession; Harold has trouble being a good father when his daughter isn't allowed in his home.

Larina's compulsive hoarding puts her on the verge of losing her 10-year-old daughter.

Sherry's hoarding has broken up her marriage and now authorities threaten to take her children and condemn her home.

It takes less than a week for 16-year old Haley to fill a bedroom with stuff; her parents hope that a visit with an extreme hoarder will scare their daughter straight.

A former ventriloquist turns her career into an obsession; Harold has trouble being a good father when his daughter isn't allowed in his home.

Larina's compulsive hoarding puts her on the verge of losing her 10-year-old daughter.

Sherry's hoarding has broken up her marriage and now authorities threaten to take her children and condemn her home.

Extreme hoarder Floyd must clear his hoard or risk losing his three year old son.

Donny has been to jail twice because of his hoard; Joyce finds comfort in her doll collection, while others see it as creepy.

A 19-year-old discovers she is pregnant in the middle of the night.

A woman with M.S. goes into labor without realizing she is pregnant.

A single mom struggling to make ends meet goes to an emergency room with what she believes is a burst appendix, but she's in for the shock of her life.

A woman believes her unborn child is actually indigestion.

Antonia overcame her food addiction to lose 190lbs, but the extra skin is keeping her from feeling confident and sexy; Natasha lost almost 300lbs after gastric bypass surgery, but now struggles with carrying a lot of saggy excess skin.

Linda is hoping skin removal surgery will give her the self-esteem she needs to be an amazing role model to her daughters; Angel hates her extra skin because it's turning her into an introvert around her family.

Shantel needs to get rid of her excess skin to gain the confidence she needs to set a positive example for her daughter; Hope has an obsession with weight loss that could make her too unhealthy to have skin removal surgery.

Melanie wants to feel normal and date, but her layers of skin are dragging her down; Lauren is so uncomfortable in her excess skin that she can't have the normal life she wants with her boyfriend.

When Beverly has weight loss surgery, three cousins are inspired to begin their own weight loss.

Stressed out Naomi struggles with her liquid diet and may reach her breaking point; Drew wants to have the weight loss surgery, but when he steps on a scale he's thrown off entirely; bed-bound Chitoka asks Dr. Procter for a house call.

After struggling with her liquid diet, Naomi learns if she is approved for surgery; Drew's new weigh-in leads him down a slippery path; family tragedy motivates Chitoka to try to become more mobile, starting by trying to leave her bedroom.

Chitoka attempts to walk outside for the first time in years; Naomi finds some things remain the same post-surgery; Drew risks getting his surgery canceled entirely if he doesn't fight for it and lose weight.

The family anxiously wait while Drew undergoes surgery; Chitoka surprises even the doctor when she pushes herself further than ever before; things take an unexpected turn when Naomi and her boyfriend go on their first dinner date after surgery.

After years of being bedridden, Chitoka's surgery day is finally here, but her size makes the procedure extremely dangerous; Naomi shares a secret with her friends; the cousins reveal their startling transformations at Beverly's birthday party.

A couple's baby is born without a heartbeat; a woman experiences excruciating headaches.

A woman has shortness of breath, chest and joint pain, extreme fatigue and cough; strange symptoms appear in an energetic kindergartener.

A baby boy has bouts of vomiting and diarrhea from the day of his birth; a young woman experiences blackouts after she hits puberty.

A college student is misdiagnosed with pneumonia.

An overweight girl experiences dizziness and shortness of breath with any physical exertion.

A baby girl turns blue 30 minutes after her birth.

A baby boy has bouts of vomiting and diarrhea from the day of his birth; a young woman experiences blackouts after she hits puberty.

A college student is misdiagnosed with pneumonia.

An overweight girl experiences dizziness and shortness of breath with any physical exertion.

A baby girl turns blue 30 minutes after her birth.

A couple's baby is born without a heartbeat; a woman experiences excruciating headaches.

A woman has shortness of breath, chest and joint pain, extreme fatigue and cough; strange symptoms appear in an energetic kindergartener.

Liz, completely bed-bound, has severe lymphedema that makes it impossible to walk; utterly isolated, Liz has no friends, battles depression and lives with a mother too ill to take care of her.

Chuck weighs almost 700 pounds; he has had to downsize his business and his wife feels like a single-parent who is ready to leave him.

Christina has not left her house in two years due to her size; she has eaten herself into a state that will soon kill her if she does not change.

Over 11 years, Melissa has lost 500 pounds and saw her weight drop to 137 pounds; now facing marital problems, three pregnancies, and life as a single mom, Melissa is struggling with a 150-pound weight gain and finds herself at a crossroads.

Weighing over 700-lbs, Nicole is on the verge of leaving her two young children motherless; trying to survive a family of addicts, she commits to Dr. Nowzaradan's diet program, but crisis threatens to derail all her hopes for weight-loss.

Ashley hits an emotional wall and is desperate for skin surgery, but she's not losing any weight; after being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

After a lifelong struggle with obesity, the three Perrio siblings travel to Houston in a last-chance journey to lose weight.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Kirsten is close to losing all her mobility, and while she's trying to control of her obesity, she's also in danger of losing her troubled son.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Kirsten is close to losing all her mobility, and while she's trying to control of her obesity, she's also in danger of losing her troubled son.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Half of Mary's body is a size 18 while the other half is a size 8; Anthony's cyst is in the area called the "Triangle of Death;" Shane wants to get a lump off his back; Brandi is anxious about getting a lump removed from her chest.

Belinda's lump on her neck causes her to basically be immobile; Nicole won't get married until she gets her armpit lump removed; Adela's chest and back are covered in wisdom spots; Nick foolishly removes a lipoma at home and now needs Dr. Lee.

Diane has tumors all over her body that have ruined her life; Will fears his shoulder lump will be ripped open at work; Anthony's daughters force him to get his lump examined; a woman detests her hideous varicose veins.

Taylor has a large bump at the base of her spine that is far more dangerous than she realizes; John jokes about his hip lump, but it's no laughing matter; Noelle had her ears stretched as a teen, but now wants them repaired.

Louis is a veteran who is covered in scaly, dry skin that makes him feel like an alligator; Irais's kids are bullied because of the embarrassing growth on her head; Johnny has been living with a stubborn lump on his back for too long.

Patrick's nose is covered by huge bumps, and he can barely breathe; Aziza and Lauren are friends who bonded over their matching wrist lumps; Joe has a mound in the middle of his forehead that looks like a third eye.

April is covered in bumps that disfigure her arms; Genner flies all the way from the Philippines to have Dr. Lee help with his bumpy nose; Chris suffers from psoriasis that nearly covers his body and a bump on his head.

Matt has a skin condition that causes tumors to grow all over his body; Yamileth hasn't pursued her dreams because of the lump on her neck; Pat is covered with dark spots from her neck to her abdomen; Jennifer has a unicorn bump on her forehead.

Amber has hundreds of tumors on her face; Antonio has a mound on his spine and is afraid it might be impossible to remove; sisters Cheri and Janice both suffer from possibly matching lumps; Tatiana has an embarrassing bump on her butt cheek.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Taylore is a beautiful young woman who has unsightly elf-like bumps on her ears; Jose never goes out because of the baseball-sized lump on his head; Ken is covered in painful bumps that make it difficult to do everyday things.

Josh has a large knot on his head resulting from a car crash from 18 years ago; Brittney is covered in mysterious bumps; TJ has a hard, curious lump protruding from his side; Luis has a bump on his shoulder and his daughters fear it's dangerous.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Leonard has an alarming bump hanging off of his arm that looks like it's breaking through the skin; Brandon has several lumps on his head that make him fearful for his life; Jess gets a noticeable lump on her butt after falling down the stairs.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Leonard has an alarming bump hanging off of his arm that looks like it's breaking through the skin; Brandon has several lumps on his head that make him fearful for his life; Jess gets a noticeable lump on her butt after falling down the stairs.

Extreme hoarder Floyd must clean his home or risk losing his 3-year-old son, Charlie.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

Gary's house is so full that he is forced to sleep outside on a makeshift bed.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

A man injured by a boat propeller; a deadly chain of events; the ER comes to a standstill.

Two gunshot victims; a jogger goes into a coma; the ER staff becomes detectives.

A newlywed's hand gets stuck in a kitchen appliance; a student with an injury down under; a heavy drinker has complications.

A college student's face covered in a plaster mask; a stroke patient's heart keeps stopping and restarting without intervention.

A patient's violent outbursts; a man's heart fails; a patient with severe burns prays for a miracle.

A patient gets drunk to save his life; a patient is stiff after a fall; a patient tasered by the police; a boy impaled by a bottle rocket in the neck.

A man with half a torso learns if his rare bone-eating disease is back; a young girl undergoes surgery to stop her facial tumor from choking her; a boy is born with half a face.

A man with cold-like symptoms loses his limbs and lips; a young girl has a prematurely fused skull; a boy with brittle bones and a rare skin condition gets life-changing surgery; a woman suffers from a disfiguring birthmark; with bonus content.

A woman suffers from cyclical vomiting syndrome; a man with warts all over his body searches for cures; a girl fights for a surgery that could allow her to speak for the first time; with bonus content.

A man's maimed hand is sewn into his stomach to avoid amputation; a young girl is born with a deformed mouth and jaw; a boy's organs are inverted; a man who can't smile finds love; with bonus content.

A boy tries to get his balloon facial tumor removed; a woman who is allergic to UV light must take precautions; a woman fears her birthmark is still growing; a boy with undeveloped legs walks on all fours; with bonus content.

A boy who can't stop eating undergoes a series of operations to save his life; a young man who is more than 7-feet tall learns if he's still growing; a boy is born without eyes; Irish twins' muscles and flesh turn to bone; with bonus content.

A woman suffers from cyclical vomiting syndrome; a man with warts all over his body searches for cures; a girl fights for a surgery that could allow her to speak for the first time; with bonus content.

A man's maimed hand is sewn into his stomach to avoid amputation; a young girl is born with a deformed mouth and jaw; a boy's organs are inverted; a man who can't smile finds love; with bonus content.

A boy tries to get his balloon facial tumor removed; a woman who is allergic to UV light must take precautions; a woman fears her birthmark is still growing; a boy with undeveloped legs walks on all fours; with bonus content.

A boy who can't stop eating undergoes a series of operations to save his life; a young man who is more than 7-feet tall learns if he's still growing; a boy is born without eyes; Irish twins' muscles and flesh turn to bone; with bonus content.

A man with half a torso learns if his rare bone-eating disease is back; a young girl undergoes surgery to stop her facial tumor from choking her; a boy is born with half a face.

A man with cold-like symptoms loses his limbs and lips; a young girl has a prematurely fused skull; a boy with brittle bones and a rare skin condition gets life-changing surgery; a woman suffers from a disfiguring birthmark; with bonus content.

At age 58, Rose had almost given up and eaten herself to death, but it turned out her family needed her too much for her to go; now she has more than 400 pounds to lose if she wants to get healthy for them, and she's determined to do it.

A mother of two who is too ashamed of her size to be seen with her children; she is committed to regaining her confidence and being a proud mother.

Susan, 37-year-old woman, has never lived on her own because of her weight, is finally seeking help to get out on her own.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden; Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live.

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

With the support of his fiancé, Kathryn, Robert turns to Dr. Nowzaradan in a final, desperate attempt to save his life; he tries to reverse a lifelong food addiction that has left him bed-bound, saddled with grotesque lymphedema, and nearly 900-lbs.

After losing 250lbs, Nikki is on her way to skin surgery, but when a close friend dies from weight loss surgery, Nikki's progress is derailed by fears.

With her weight spiraling, Stephanie needs her mom's help to care for her three kids; she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

With her weight spiraling, Stephanie needs her mom's help to care for her three kids; she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

After losing 250lbs, Nikki is on her way to skin surgery, but when a close friend dies from weight loss surgery, Nikki's progress is derailed by fears.

Identical twins enlist Lisa's help to unlock the mystery of why they were placed for adoption; Chris hopes to fulfill the wishes of a deceased father by tracking down the first-born son he and his wife had placed for adoption.

A surprisingly troubled outcome with her birth mother prompts an adoptee to find her father, leading to life-changing truths; a woman tries to repair relationships with the biological father she just met and the father who raised her.

A woman enlists Lisa's help to find her birth mother, but unearths a 40-year-old secret in the process.

Chris and Lisa join forces in an attempt to solve the childhood mystery of why a woman was separated from her birth family at the age of two.

After a joyful reunion with the daughter he was forced to give up, Jon now struggles to maintain their relationship; high school sweethearts who placed their son up for adoption happily meet his adoptive parents and participate in his wedding.

Lisa hopes that locating a man's biological mother will finally allow him to overcome his lifelong struggle with abandonment; Chris locates a woman's only child and delivers the difficult details of her daughter's birth story.

Twins Kandi and Brandi have a combined weight of over 1,100 pounds and fear losing each other to obesity, so they decide to make a change together.

Erica regrets not keeping a promise to her mom and hopes her siblings will help, but they're reluctant based on her past failures.

When Travis gets too big to walk down the aisle, he promises to give his wife a proper wedding; he gains more weight, leaving Dr Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.