A surgical resident puts her training to the test when a mugging survivor arrives with two bullet wounds.

A man with a slashed wrist has a startling secret; a woman gives birth unexpectedly, shocking the ER staff; a surgeon requires urgent treatment after falling off a bed while trying to help his patient.

A pianist's finger goes missing after getting accidentally sawed off; a man's pacemaker threatens to kill him; a man behaves bizarrely.

A Halloween zombie with a problem below the belt mystifies doctors; two unconscious men are involved in an accident, a doctor makes a mistake that amazingly explains a patient's condition.

Weighing over 700-lbs, Nicole is on the verge of leaving her two young children motherless; trying to survive a family of addicts, she commits to Dr. Nowzaradan's diet program, but crisis threatens to derail all her hopes for weight-loss.

Chay has eaten his way to 600 pounds to cope with the emotional turmoil of his childhood; he loses his emotional support and searches for new strength to take control of his life.

Pauline is 51-years-old and nearly 700 pounds; her addiction to food has taken over the life of her son and primary caretaker.

Pauline must keep her weight loss on track after a medical emergency; Chay admits to being a transgender woman, and the resulting stress may threaten his weight loss journey.

Mother of four LaShanta has been bed-bound for two years, and she relies on her kids to keep her cleaned and fed; her last chance to break the cycle of food addiction is to join Dr. Now's program, but it will take a village to get her out the door.

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

Lacey wants skin removal surgery, but Dr. Now begins to wonder if she even wants to lose weight; in Houston, Mercedes and her kids face destitution.

Kirsten is close to losing all her mobility, and while she's trying to control of her obesity, she's also in danger of losing her troubled son.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Charles replaced one addiction with another when he quit doing hard drugs. Now his BMI is over 100 and he can't stop eating. He needs Dr. Now's help, but with his brother doing everything for him, is he too comfortable to make the trek to Houston?

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Charles replaced one addiction with another when he quit doing hard drugs. Now his BMI is over 100 and he can't stop eating. He needs Dr. Now's help, but with his brother doing everything for him, is he too comfortable to make the trek to Houston?

Kirsten is close to losing all her mobility, and while she's trying to control of her obesity, she's also in danger of losing her troubled son.

Ashley hits an emotional wall and is desperate for skin surgery, but she's not losing any weight; after being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

Zsalynn's 360-body lift procedure proves to be more challenging than expected; lonely and depressed since her gastric surgery, Olivia wants skin removal surgery but struggles to lose the weight to qualify.

After gastric bypass surgery, Chad quickly sheds his dangerous weight but faces a medical crisis when he does not follow the doctor's orders.

Krystal begins overeating to shield herself with a protective layer of obesity after suffering years of abuse; once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again.

A year since her weight-loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat her if she can't find a way to control her eating habit and start walking again.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

Doug has lost over 200 pounds and is more involved with his family life. He is now an example of healthy habits, but eating disorders threaten to derail his progress.

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

Doug has lost over 200 pounds and is more involved with his family life. He is now an example of healthy habits, but eating disorders threaten to derail his progress.

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

At over 700 pounds, Teretha's life is confined to a bed, which is a long way from her former job representing Detroit's healthy eating program; a gastric bypass will hopefully save her life.

An overweight woman struggles with flesh-eating bacteria and butterfly shaped fat deposits; unexpected news threatens her weight loss journey.

In order to keep pace with her daughter Charly's impressive weight loss, Charity must do something she's never done and find a way to go it alone.

JT is almost 900lbs with a 100-lb lymphedema mass on his leg and a food addiction that is bound to kill him if he doesn't change; his girlfriend takes him to Houston, but when his behavior drives her away, JT is left with only Dr. Now to help.

Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can't get through to her, the only thing that might help her break the cycle is a once-in-a-lifetime turn of events.

Kenae' is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae' turns to food to fill the void.

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky; Lacey's weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

Michael's massive body has left him dependent upon his family, and he must learn to control his anger issues around food, lose weight and address the root of his issues or risk losing everything.

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father for help instead. Aaron must learn to care for himself to avoid eating himself to death.

Michael's massive body has left him dependent upon his family, and he must learn to control his anger issues around food, lose weight and address the root of his issues or risk losing everything.

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father for help instead. Aaron must learn to care for himself to avoid eating himself to death.

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky; Lacey's weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

Chandra is afflicted by a unknown condition that has left his body riddled with hundreds of tumors; in a race against time to find a cure.

Nicky Freeman is 40 years old with the body of a 10-year-old, and Gabby Williams is a 6-year-old who is like a newborn, but doctors do not understand why.

Autumn wants to make up for lost time with her son, but the excess skin from major weight loss is holding her back; Cody always pretended to be happy when he was 500-lbs, but after losing the weight, he's covered in skin and is sick of pretending.

Melanie wants to feel normal and date, but her layers of skin are dragging her down; Lauren is so uncomfortable in her excess skin that she can't have the normal life she wants with her boyfriend.

Lindsey lost 140 pounds, but her sagging skin keeps her athletic dreams out of reach; Derek wants to pass the Police Academy physical but his excess skin prevents him from training.

Annette lost over half of her body weight, but her excess skin is a painful reminder of years of overeating; Callisto lost 250 pounds and became a model, but the shame of her loose skin put her passion and marriage on hold.

An overweight girl experiences dizziness and shortness of breath with any physical exertion.

A baby girl turns blue 30 minutes after her birth.

Mysterious symptoms appear for a man who recently underwent minor surgery.

A new baby is plagued with health problems.

Doctors can't pinpoint the cause of the array of ailments a woman has been suffering from for more than 50 years.

A woman who successfully gives birth after two miscarriages faces challenges.

The world's tallest child can't stop growing; a man learns how to use a dead man's hand; a teenager discovers he has a parasitic twin and it's been growing inside him; a limbless girl gets fitted for prosthetic limbs.

A woman who slept through the birth of her child, hopes to find a diagnosis for her sleeping condition; a man with giant genitals seeks help; a 2.5ft teenager hopes to find out what stalled his growth.

A boy can't stop his giant foot from growing; a woman with bubbly skin and her kids embrace their condition; a dwarf boy who defied the odds has one more challenge to face; a man with a facial tumor must conquer his fear of surgery.

A boy born with no eyes; a separated conjoined twin adjusts to life after losing his twin brother; two brothers suffer from a very rare bone condition; a boy living with a huge facial growth finally gets a diagnosis.

A woman with an extremely rare skin disorder looks more than twice her age; a baby undergoes risky surgery to cure a mysterious brain condition; three brothers with the same genetic disorder hope for a miracle.

Doctors operate on a huge neck tumor; an English teen is diagnosed with a rare aging condition; an Indian baby is born with an extra head.

A boy can't stop his giant foot from growing; a woman with bubbly skin and her kids embrace their condition; a dwarf boy who defied the odds has one more challenge to face; a man with a facial tumor must conquer his fear of surgery.

A boy born with no eyes; a separated conjoined twin adjusts to life after losing his twin brother; two brothers suffer from a very rare bone condition; a boy living with a huge facial growth finally gets a diagnosis.

A woman with an extremely rare skin disorder looks more than twice her age; a baby undergoes risky surgery to cure a mysterious brain condition; three brothers with the same genetic disorder hope for a miracle.

Doctors operate on a huge neck tumor; an English teen is diagnosed with a rare aging condition; an Indian baby is born with an extra head.

The world's tallest child can't stop growing; a man learns how to use a dead man's hand; a teenager discovers he has a parasitic twin and it's been growing inside him; a limbless girl gets fitted for prosthetic limbs.

A woman who slept through the birth of her child, hopes to find a diagnosis for her sleeping condition; a man with giant genitals seeks help; a 2.5ft teenager hopes to find out what stalled his growth.

A drug dealer stages an alligator attack; a desperate man uses a corpse to stand in for him.

An innocent man goes underground after refusing to commit a crime; a man who seems to have it all stages a plane crash to escape his life.

A husband and wife try to hide from drug dealers and the law; a man has a cold-blooded plan to cash in on his life insurance.

Kit and Jourdan's fairytale wedding turns into a fight for the groom's life; Frank and Jen's nuptials are derailed when they get kidnapped and taken for ransom; Gus and Jen's sand ceremony takes on a whole new meaning.

Jon and Christine's wedding takes a scary turn when the bride suddenly goes blind; Frank and Patricia plan a picture perfect wedding only to capture a moment that ends in the ER; everyone at Landon and Jamie's wedding falls mysteriously ill.

Erik and Ashley's pirate-themed wedding turns into a treasure hunt for the ER.; Taylor and Ellie's plans go up in smoke when their walk down the aisle becomes a sprint toward safety; Connor and Sabrina's wedding day gets quite literally swept away.

A best friend's offer to be a surrogate results in a life-threatening pregnancy; a woman is bitten by a deadly snake three weeks before her due date; a cupcake famed for inducing labor.

A woman gives birth while trapped in an elevator; two truckers deliver a baby in a diner; a prolapsed umbilical cord threatens a baby's life.

A grandma-to-be acts as surrogate for her daughter's baby; a very premature baby arrives at a playground; a woman gives birth at home.

A cop delivers a baby at a gas station; a woman has a baby six days after learning she's pregnant; a singer gives birth during a talent competition.

Kendra Herrin and her sister, Maliyah, were born attached at the abdomen and pelvis; doctors use a groundbreaking surgical procedure to separate the girls.

Four moms-to-be who are morbidly obese; these women challenge the perception and the odds on their journey to motherhood.

After a negative pregnancy test, Monique delivers a baby in her bathroom.

Dana is having debilitating stomach pains at work; the paramedics arrive just in time to deliver a baby.

A 20-year old woman suffers abdominal pain while at work; while waiting it out she realizes she is delivering a baby.

A flight attendant has mysterious pains in her stomach; she is stunned to learn she is in labor.

A woman in top shape suddenly has debilitating cramps; at the hospital she is stunned to learn she is pregnant and in labor.

Back pain is typical for Andrea, but when she starts bleeding severely, she must call 911.

Anna cannot believe her eyes when she gives birth to a baby in her kitchen.

Kayla goes to a small-town clinic and gets the news she's in labor; with few supplies and a tornado looming, she must be transferred to another hospital over 100 miles away.

A single mom struggling to make ends meet goes to an emergency room with what she believes is a burst appendix, but she's in for the shock of her life.

A woman believes her unborn child is actually indigestion.

A woman with a broken pelvis suddenly discovers she is pregnant, and both mother and child are in danger.

A woman who has accepted that she may never have a child is rushed to a hospital with cramps attributed to work stress and is shocked to find out she's pregnant and in labor.

A woman in top shape suddenly has debilitating cramps; at the hospital she is stunned to learn she is pregnant and in labor.

Back pain is typical for Andrea, but when she starts bleeding severely, she must call 911.

Anna cannot believe her eyes when she gives birth to a baby in her kitchen.

Kayla goes to a small-town clinic and gets the news she's in labor; with few supplies and a tornado looming, she must be transferred to another hospital over 100 miles away.

A single mom struggling to make ends meet goes to an emergency room with what she believes is a burst appendix, but she's in for the shock of her life.

A woman believes her unborn child is actually indigestion.

A woman with a broken pelvis suddenly discovers she is pregnant, and both mother and child are in danger.

A woman who has accepted that she may never have a child is rushed to a hospital with cramps attributed to work stress and is shocked to find out she's pregnant and in labor.

After a negative pregnancy test, Monique delivers a baby in her bathroom.

Dana is having debilitating stomach pains at work; the paramedics arrive just in time to deliver a baby.

A 20-year old woman suffers abdominal pain while at work; while waiting it out she realizes she is delivering a baby.

A flight attendant has mysterious pains in her stomach; she is stunned to learn she is in labor.

Dr. Lee reopens her office with new safety protocols; Monica has a large facial birthmark; Jackie has a melon-sized shoulder lump; Reginald has large, rare growths on his head.

With pop-up facts and behind-the-scenes secrets; Dr. Lee works to remove the large, rare growths on the back of Reginald's head; Che'Re has a prominent bump on her face; Juan has several painful boils on the back of his neck.

Dennis has giant growths on his head; Juan has a rare condition that he hopes Dr. Lee will understand; Natalie needs answers as to why her body is covered in dark bumps.

A behind-the-scenes episode; Audrey pops the painful bumps that cover her body; Felicia has a dark growth on her forehead; Krista sweats so much that she could fill an entire milk jug every day with her sweat.

Behind the scenes and new information; John fears the lump on his neck may suffocate him; Shoshana's forehead growth depresses her; Ashley hopes Doctor Lee can provide some relief from her three painful skin conditions.

Yaellie's itchy psoriasis all over her body; former marine Matt's large recurring lump in his armpit, twins Tracie and Stacie's matching bumps on their heads.

Behind the scenes; Joanne has a forehead growth; gauges have split Shakisaha's earlobes.

With pop-up facts and behind-the-scenes secrets; James has a squishy forehead lump; Tanisha has an arm growth and itchy scars; Ed wants a lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps.

Juicy pop-up facts and behind-the-scenes secrets are finally revealed; JD has a pear-shaped ear mass; David has two painful bumps on his neck and one on his finger; former cruise ship worker Julie hopes Dr. Lee can remove her large back growth.

All new juicy pop-up facts and behind-the-scenes secrets are finally revealed; Stephen's large nose brings unwanted attention; Veronica wants to be free of the bump on her butt crack; Marty has a large shoulder growth.

With pop-up facts and behind-the-scenes secrets; Brittany's genetic condition causes head-to-toe bumps; Leonardo has a fist-size growth on his head; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

Stacey has a growth on her shoulder that prevents her from being the playful teacher she once was; Matthew has a mysterious rash on his shin and worries it may be dangerous; Mark has a growth in his pubic area that has put a damper on his sex life.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches; Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort; Sharon has an embarrassing, stinky, squirting cyst under her breast.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Taylore is a beautiful young woman who has unsightly elf-like bumps on her ears; Jose never goes out because of the baseball-sized lump on his head; Ken is covered in painful bumps that make it difficult to do everyday things.

Josh has a large knot on his head resulting from a car crash from 18 years ago; Brittney is covered in mysterious bumps; TJ has a hard, curious lump protruding from his side; Luis has a bump on his shoulder and his daughters fear it's dangerous.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Taylore is a beautiful young woman who has unsightly elf-like bumps on her ears; Jose never goes out because of the baseball-sized lump on his head; Ken is covered in painful bumps that make it difficult to do everyday things.

Josh has a large knot on his head resulting from a car crash from 18 years ago; Brittney is covered in mysterious bumps; TJ has a hard, curious lump protruding from his side; Luis has a bump on his shoulder and his daughters fear it's dangerous.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Stacey has a growth on her shoulder that prevents her from being the playful teacher she once was; Matthew has a mysterious rash on his shin and worries it may be dangerous; Mark has a growth in his pubic area that has put a damper on his sex life.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches; Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort; Sharon has an embarrassing, stinky, squirting cyst under her breast.

The work of the staff at Baylor University Medical Center in Dallas includes a rodeo champion who was trampled by a bull.

Car-crash victims; smoker fights for breath; uncooperative patient.

The staff of Legacy Emanuel Hospital in Oregon picks up the pieces when alcohol turns sport into nightmare.

Horseback-riding accident; broken wrist; crash victims.

The emergency room of San Francisco General is almost always on total divert, which means ambulances are forced to take patients to other hospitals.

Phyllis' neighbors are complaining about the trash piling up outside; Faye realizes her hoard is killing her.

Brad's hoarding has taken over his mobile home; Mary has been evicted and has just weeks to clean out her stuff.

Hoarding has destroyed Carol's relationship with her daughter; Amy's years of collecting have turned into a massive hoard.

Laura and Margaret are both mothers and extreme hoarders; their parallel obsessions have made them prisoners in their own homes while tearing their families apart.

Deborah and Mary both start hoarding in the wake of personal tragedies; ever since Deborah killed her drug-addicted boyfriend in self-defense, she and her son have lived amid growing piles of trash and unused possessions.

9/11 trauma was the trigger for one woman; the lasting effects of a brain hemorrhage.

Debbie knows the OCD drives her hoarding; Jeff doesn't believe he is a hoarder.

A pregnant woman is shot in the abdomen; a doctor is the victim of a car burglary; a storm is preventing a patient's life-saving surgery.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change; a pregnant woman's life-threatening symptoms need urgent treatment.

An ER doctor's friend arrives at the hospital combative and out of control; a cyclist's throat is torn open when a driver opens a car door in her path; a nursing student is found passed out on the hospital floor.

The hospital is locked down when a nurse is shot in the ER; medics rush a bride from her wedding who is in an unexplained altered mental state; a doctor must perform a risky intervention to save the life of a teenage girl.

A doctor with a severe bee allergy is stung while treating a critical patient who's been stabbed in the eye; a man comes into the ER after slitting his own throat; a paramedic becomes a patient when she's struck by a mysterious illness.

A surfer is impaled between the legs; a football player's severe leg pain leads to an unexpected diagnosis; a woman is given a clot-busting drug to cure her stroke, but she has another condition that could cause that same drug to kill her.

An ER doctor's friend arrives at the hospital combative and out of control; a cyclist's throat is torn open when a driver opens a car door in her path; a nursing student is found passed out on the hospital floor.

The hospital is locked down when a nurse is shot in the ER; medics rush a bride from her wedding who is in an unexplained altered mental state; a doctor must perform a risky intervention to save the life of a teenage girl.

A doctor with a severe bee allergy is stung while treating a critical patient who's been stabbed in the eye; a man comes into the ER after slitting his own throat; a paramedic becomes a patient when she's struck by a mysterious illness.

A surfer is impaled between the legs; a football player's severe leg pain leads to an unexpected diagnosis; a woman is given a clot-busting drug to cure her stroke, but she has another condition that could cause that same drug to kill her.

A pregnant woman is shot in the abdomen; a doctor is the victim of a car burglary; a storm is preventing a patient's life-saving surgery.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change; a pregnant woman's life-threatening symptoms need urgent treatment.

Cynthia, a single mother focused on raising five kids, comes to realize what her death would mean for their future.

Dottie wants to be a better mom, so she agrees to a drastic new diet, but her child's life-threatening emergency and her own self-sabotage threaten to derail all hopes for weight-loss.

June copes with the tragic death of her son by eating, and must confront the emotional issues driving her food compulsion after gastric bypass surgery.

Devastated by the sudden loss of her son, Dottie's weight loss journey is in danger of going off track; June embarks on a plan to win approval for skin surgery; Melissa, Jessica and Matt prepare for skin removal surgery.

Dottie faces an unexpected challenge to her weight-loss when her husband's drinking problem becomes intolerable for her and her son; Cynthia starts to wonder if being there for her kids at her current weight is more important than losing more.

Holly already has one failed weight loss surgery, so to succeed this time, she must do more than change her eating habits, she must address the childhood issues that continue to plague her.

Jeanne lives in an unhygienic household with her mother and schizophrenic father; at well over 600 pounds, Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.

Dominic's life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only Dr. Now can help him learn to face life's challenges without using food to cope.

Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10; while learning to cook for his family, he began comfort-eating; now to avoid eating himself to death, Isaac must learn to take care of himself for a change.

Twins Kandi and Brandi have a combined weight of over 1,100 pounds and fear losing each other to obesity, so they decide to make a change together.

Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10; while learning to cook for his family, he began comfort-eating; now to avoid eating himself to death, Isaac must learn to take care of himself for a change.

Twins Kandi and Brandi have a combined weight of over 1,100 pounds and fear losing each other to obesity, so they decide to make a change together.

Dominic's life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only Dr. Now can help him learn to face life's challenges without using food to cope.

After successful sleeve gastrectomy procedures, the Dreier twins collectively lose more than 400 pounds and work toward skin surgeries when a major life event disrupts their world and threatens their progress.

Christina has not left her house in two years due to her size; she has eaten herself into a state that will soon kill her if she does not change.

Donald has difficulty walking and relies on his parents to take care of him, so he gets motivated to begin his weight loss journey.

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

Having her daughters help bathe her is not how Chrystal pictured parenting but she is so large that there's no other option; Chrystal wants Dr. Now's help but she didn't know that bringing her childhood trauma to light would be part of the deal.

When Annjeanette was nine, a campaign was established to send her to fat camp; she hated that her weight had become a source of public shame and she has struggled to overcome her food addiction; now, she must change her habits to save her life.

Patrick's weight has never been a bother, but now he's so big that it's getting in the way of his relationship with his daughter; if he wants to see her graduate high school, he'll have to reverse course.

At over 600 pounds, Angie is trying to get to Houston to see Dr. Nowzaradan, in hope of getting weight loss surgery to save her life; family conflict and disagreements may stop her from being able to do what she needs before she even gets the chance.

Cillas' food addiction is getting in the way of his ability to be there for his fiancée, Jessica, and her three daughters; if he doesn't lose weight soon, he knows he'll lose either his girls or his life.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Cillas' food addiction is getting in the way of his ability to be there for his fiancée, Jessica, and her three daughters; if he doesn't lose weight soon, he knows he'll lose either his girls or his life.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

At over 600 pounds, Angie is trying to get to Houston to see Dr. Nowzaradan, in hope of getting weight loss surgery to save her life; family conflict and disagreements may stop her from being able to do what she needs before she even gets the chance.

Krystal S. has finally met the man of her dreams, but she won't let herself marry him until she can be sure that she won't become bedridden and force him into the role of caretaker.

Penny has been bedridden for four years and moves to Texas to have gastric bypass; her unwillingness to make lifestyle changes could mean failure.

Penny returns to Maryland believing she can lose weight; Tara continues to lose weight and is dating for the first time.

Unable to stand for more than a short period of time, Karina's weight places a burden on her parents and drives a wedge between her and her sister.

Tamy faces a tough choice when her husband wants her back, but only if she moves away from Houston and Dr. Now's program; Karina's weight loss begins to slow, but she finds happiness dating a guy Dr. Now is surprised to see in his clinic again.

Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth; now he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

After getting his surgery canceled and living in his van by the beach, surgery may be the break David has been waiting for his whole life; Syreeta suffers a devastating personal tragedy that only strengthens her desire to become a mother.

Twenty years after her father died as the result of a botched weight-loss surgery, Carrie is on the brink of eating herself to death; she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband, Chris.