A teen's leg grows so large it affects his mobility.

A woman starts growing uncontrollably.

A woman surviving blindness and albinism suffers another disease.

A toddler has unexplained bleeding; a college student has intense cramps.

After meeting and falling in love at a bariatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their relationship and their lives.

An overweight woman struggles with flesh-eating bacteria and butterfly shaped fat deposits; unexpected news threatens her weight loss journey.

Laura has used food to cope with her emotions; she is confined to a wheelchair and relies on an oxygen tank to breathe and her husband and mother to survive.

A woman whose extreme obesity has left her nearly immobile must overcome both her physical and emotional pain if she is ever to live a normal life again.

Alicia, all smiles and laughter on the outside, secretly fears that her food addiction will kill her before she can marry her long-time love or watch her nieces grow up.

Liz, completely bed-bound, has severe lymphedema that makes it impossible to walk; utterly isolated, Liz has no friends, battles depression and lives with a mother too ill to take care of her.

Unable to stand for more than a short period of time, Karina's weight places a burden on her parents and drives a wedge between her and her sister.

Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.

After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon to over 500 pounds; she has become a hermit and hopes to restart her life so she can better care for her son, Zachary.

Fearing he'll suffer the same fate as 700-pound brother David, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.

After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon to over 500 pounds; she has become a hermit and hopes to restart her life so she can better care for her son, Zachary.

Fearing he'll suffer the same fate as 700-pound brother David, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.

Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.

Tyler's hands are so dry, cracked and painful that he considers getting them amputated; Ebonee covers the tiny bumps around her eyes with sunglasses; Ralph feels like a cyst factory with painful cysts covering his back.

Kelly has a massive shoulder growth; Erica stabbed her hand with a pencil 45 years ago and believes the lead remains trapped in her palm; Paula's painful and swollen feet ooze a substance that emits the foulest of odors.

Dr. Lee has a surprise for Paula, who has oozing, odoriferous and painful legs; Mike needs to get rid of the bump on his head before two major life events; Amanda feels inadequate for her husband because of the saggy growth on her back.

Alyse has been suffering from a burning rash that feels like it's rubbing away her existence; Terry has become too big for his britches due to a painful butt cheek lipoma; James has demons on his back that are ruining his life.

Krystal, a witch, looks to clear a curse of a cyst from her face; Keven wants to get a butt lipoma removed to get his tush back into a regular shape; Raquel, Dr. Lee's esthetician BFF, almost suffocates Dr. Lee with love and a facial.

J-Fab is the life of the party, but her shoulder bump is seriously cramping her style; Dan is a gentle giant with lumps on his head that add a few inches; Teresa's red face and bumpy nose make her feel like a monster.

Fit guy Alonso wants to show off his progress in the gym, but his 70 lipomas are holding him back; Porscha is a comic book enthusiast with two symmetrical lumps on her face; Jeffrey has a leaky lump named Larry on the back of his head.

Robert carries the weight of providing for his family and the weight of the huge lump on his head; Christina has liquid-filled growths next to her eyes; Felipe, a photographer with a dry skin condition so severe he risks losing his career.

Natasha has ambitions of becoming a model, but her massive ear keloids are keeping her off the runway; eight-year-old Wynter wants her scaly mermaid skin cured; Dr. Lee's bestie, Raquel, needs help with a new product for a private area.

Nhan has an extreme, red birthmark that covers half his face; Debbie worries that her shoulder lump will prematurely age her; Justin is a dude rockin' a man bun, but he's having no fun due to the bumps poking through his scalp.

Jess is a widower looking for love who is stuck with a giant bump on his neck; Cherish developed a leopard-print face during pregnancy; former NFL defensive tackle Marcell Dareus hopes Dr. Lee can tackle his forehead lipoma.

Brent has a tricep bump potentially intertwined in his muscle; Jeb loves the beach but refuses to go because of the massive number of blackheads, pimples, and cysts all over his body; Wanda's mysterious mark that caves in her side.

Don's psoriasis has completely taken over his body; Jeff has a large growth on his spine; Sara has an extra set of breasts and nipples.

Robert is back to see if Dr. Lee and Dr. Umar can remove his recurring head keloid for good; Justice has small lesions all over her body; Mike has hundreds of lipomas that bring him great discomfort.

Robert has thousands of unique bumps on his arms that Dr. Lee has never seen; Alexis has a painful cheek cyst that oozes and has a pungent odor; Stuart's cluster of back bumps disgusts his wife but thrills Dr. Lee.

Dr. Lee faces off with iguana-wrangler Madison's head growths; Chanel suffers from painful cyst tunnels beneath her armpit skin that leak and smell like the food she eats; the dark purple birthmark on Eddie's nose has made him a recluse.

Steven's bump is so large, his daughter thinks he is growing a monster on his back; Catherine's arm lump has grown so big that it's nearly up to her armpit; Ethan suffers from an irritating rash in an uncomfortable and awkward place on his body.

Casey's birthmark covers most of her face, head and neck; James has mysterious massive growths on his inner thigh and lower abdomen; Jerry had to hang up his rock star vocal cords when a lump grew out the side of his throat.

Robert has thousands of unique bumps on his arms that Dr. Lee has never seen; Alexis has a painful cheek cyst that oozes and has a pungent odor; Stuart's cluster of back bumps disgusts his wife but thrills Dr. Lee.

Dr. Lee faces off with iguana-wrangler Madison's head growths; Chanel suffers from painful cyst tunnels beneath her armpit skin that leak and smell like the food she eats; the dark purple birthmark on Eddie's nose has made him a recluse.

Steven's bump is so large, his daughter thinks he is growing a monster on his back; Catherine's arm lump has grown so big that it's nearly up to her armpit; Ethan suffers from an irritating rash in an uncomfortable and awkward place on his body.

Casey's birthmark covers most of her face, head and neck; James has mysterious massive growths on his inner thigh and lower abdomen; Jerry had to hang up his rock star vocal cords when a lump grew out the side of his throat.

Don's psoriasis has completely taken over his body; Jeff has a large growth on his spine; Sara has an extra set of breasts and nipples.

Robert is back to see if Dr. Lee and Dr. Umar can remove his recurring head keloid for good; Justice has small lesions all over her body; Mike has hundreds of lipomas that bring him great discomfort.

A woman cracks under the pressure of jail life; a woman who is pregnant finds herself in the middle of a jailhouse brawl; a heroin addict chooses to stay in jail.

A woman works through the fallout of her addiction; a woman involved in a drug cartel seeks redemption; a pregnant woman prays; a woman attempts to smuggle contraband.

A jail newcomer gets more than she bargains for; a young mother's release is postponed; the tenth trip for a heroin addict.

A crack-addicted pregnant prostitute finds safe haven in jail; two best friends share a heroin addiction; a prostitute struggles to overcome her past.

A woman is arrested for smuggling drug paraphernalia into court; two heroin addicts turn to each other for support; a life of prostitution supports a woman's drug habit.

A woman turns to drugs to numb the pain of her divorce; a crack addict attempts to head-butt an officer; a dental office assistant is arrested for stealing.

Debbie knows the OCD drives her hoarding; Jeff doesn't believe he is a hoarder.

Linda's family is on the edge of collapse because of her hoarding; Norski has overcome addiction but can she kick the hoarding habit.

Michael has six weeks to clean his house or he will go to jail; a motivational speaker can not manage her own life.

Debbie turned to hoarding after a confession ended her marriage; with illness in her family, Julie hoards to ease the pain.

Phyllis' neighbors are complaining about the trash piling up outside; Faye realizes her hoard is killing her.

Brad's hoarding has taken over his mobile home; Mary has been evicted and has just weeks to clean out her stuff.

A teenager whose body is aging ten times faster than normal, a girl with a massive tumor in the middle of her face needs emergency care and a woman battling a rare disorder can't stop eating.

Featuring an eight foot tall teen, a boy from India who possesses his own tail, a man with super sized muscles and a lobster woman.

The world's tallest child can't stop growing; a man learns how to use a dead man's hand; a teenager discovers he has a parasitic twin and it's been growing inside him; a limbless girl gets fitted for prosthetic limbs.

A woman with an extremely rare skin disorder looks more than twice her age; a baby undergoes risky surgery to cure a mysterious brain condition; three brothers with the same genetic disorder hope for a miracle.

A man born with an extra set of legs finds out whether they can be surgically removed, doctors attempt to recreate a jaw for a young boy who was mauled by a hyena and a woman living with not one, but two rare conditions.

A teenager in desperate need of surgery to remove a face tumor, a woman whose body is turning to stone, and a man that has found the perfect use for his enormous arm.

The world's tallest child can't stop growing; a man learns how to use a dead man's hand; a teenager discovers he has a parasitic twin and it's been growing inside him; a limbless girl gets fitted for prosthetic limbs.

A woman with an extremely rare skin disorder looks more than twice her age; a baby undergoes risky surgery to cure a mysterious brain condition; three brothers with the same genetic disorder hope for a miracle.

A man born with an extra set of legs finds out whether they can be surgically removed, doctors attempt to recreate a jaw for a young boy who was mauled by a hyena and a woman living with not one, but two rare conditions.

A teenager in desperate need of surgery to remove a face tumor, a woman whose body is turning to stone, and a man that has found the perfect use for his enormous arm.

A teenager whose body is aging ten times faster than normal, a girl with a massive tumor in the middle of her face needs emergency care and a woman battling a rare disorder can't stop eating.

Featuring an eight foot tall teen, a boy from India who possesses his own tail, a man with super sized muscles and a lobster woman.

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can't go; Chris' son Garrett, already 600 pounds at age 20, is game to join the journey.

Nikki finds her career as a costume designer threatened by immobility, so she undergoes gastric bypass and confronts the emotional causes for her eating.

Ashley confronts medical setbacks and struggles to get past the trauma that ignited her eating disorder.

Weight loss leads to exciting things when Julian and his wife Irma adopt a baby, but fatherhood might distract Julian from his goals; Cindy needs to change her attitude to lose some weight.

Born as "Matthew," Destinee never felt like she fit in; now, having come out as a 600-pound transgender woman, she likes her curves, but she will need to say goodbye to them if she wants to be approved to transition completely.

Margaret succeeds in getting surgery, but Dr. Now is dismayed when a few months later she and her mom revert to their old ways; Megan grows impatient with her slow weight loss, and if Dr. Now doesn't approve her for surgery soon, she might quit.

Ontreon hopes that surgery can make him a better husband to his wife Musa, but he struggles to move past the grief that's blocked him for years; Wess is doing great post-surgery, but his next goal is crucial to his success.

When Annjeanette was nine, a campaign was established to send her to fat camp; she hated that her weight had become a source of public shame and she has struggled to overcome her food addiction; now, she must change her habits to save her life.

When Angela's family is unable to accompany her on her weight-loss journey to Texas she is unsure what to do; at the last minute, she reaches out to an old flame, Eric, who still has love for her and is willing to make the trip.

Mother of four LaShanta has been bed-bound for two years, and she relies on her kids to keep her cleaned and fed; her last chance to break the cycle of food addiction is to join Dr. Now's program, but it will take a village to get her out the door.

When Angela's family is unable to accompany her on her weight-loss journey to Texas she is unsure what to do; at the last minute, she reaches out to an old flame, Eric, who still has love for her and is willing to make the trip.

Mother of four LaShanta has been bed-bound for two years, and she relies on her kids to keep her cleaned and fed; her last chance to break the cycle of food addiction is to join Dr. Now's program, but it will take a village to get her out the door.

When Annjeanette was nine, a campaign was established to send her to fat camp; she hated that her weight had become a source of public shame and she has struggled to overcome her food addiction; now, she must change her habits to save her life.

John and Lonnie are two brothers from opposite ends of the spectrum; estranged for years, the brothers are now brought together by a common need to lose weight while they still can.

Melissa weighs a shocking 673 pounds, and decides to begin her seven-year weight-loss journey toward a healthier life.

Melissa struggles to get to her ideal weight after starting her weight loss journey from 650 pounds with gastric bypass.

Lindsey has a white picket fence, a loving husband and a great job, but her food addiction threatens to ruin everything; as she embarks on a weight loss journey to save her life, her husband may provide more harm than support.

Bethany has two daughters who live in fear of losing their mom to her food addiction; once an addiction counselor, Bethany has gotten so big that she can no longer work; now she risks losing her life if Dr Now can't help her curb her own addiction.

JT is almost 900lbs with a 100-lb lymphedema mass on his leg and a food addiction that is bound to kill him if he doesn't change; his girlfriend takes him to Houston, but when his behavior drives her away, JT is left with only Dr. Now to help.

Gina and wife Beth live with Gina's mother, but she and Gina's sister blame Beth for Gina's spiraling weight problem; it will take all Gina's will to leave home for Houston to get Dr Now's help, to save her life and her marriage.

When Travis gets too big to walk down the aisle, he promises to give his wife a proper wedding; he gains more weight, leaving Dr Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.

Joyce needs home health care and hasn't left the house in three years; getting to Dr. Now in Houston is just the first step and when he prescribes therapy where Joyce must revisit an unhappy past with her mom; it might be more than she can handle.

Shantel's brother Carlton lives downstairs but she hardly ever sees him because at 600 lbs each, neither can do the stairs safely; to break free from a death spiral of codependent eating they need Dr. Now's help to reforge their sibling relationship.

Joyce needs home health care and hasn't left the house in three years; getting to Dr. Now in Houston is just the first step and when he prescribes therapy where Joyce must revisit an unhappy past with her mom; it might be more than she can handle.

Shantel's brother Carlton lives downstairs but she hardly ever sees him because at 600 lbs each, neither can do the stairs safely; to break free from a death spiral of codependent eating they need Dr. Now's help to reforge their sibling relationship.

When Travis gets too big to walk down the aisle, he promises to give his wife a proper wedding; he gains more weight, leaving Dr Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.

Lauana lost 170-lbs to find her tiny frame swamped by excess skin; after losing over 200-lbs, Tim's skin gets in the way of being a great dad.

Megan feels physically and mentally trapped with excess skin under her clothes; Yalena's extreme weight loss counts for nothing unless she sheds her excess skin.

Melissa lost 235 pounds, but her confidence is still low because of her excess skin; Jeff has lost 300 pounds, but continues to hide himself from the world.

Nicky Freeman is 40 years old with the body of a 10-year-old, and Gabby Williams is a 6-year-old who is like a newborn, but doctors do not understand why.

Kenadie, now age 6, is 30-inches tall and weighs 14 pounds, which defies doctors' expectations of her survival.

Seven-year-old primordial dwarf Kenadie struggles to confront the possibility of early puberty and her terrifying fear of Halloween costumes.

Chandra is afflicted by a unknown condition that has left his body riddled with hundreds of tumors; in a race against time to find a cure.

A young boy with a life-threatening neck growth seeks treatment; a baby born with eight limbs undergoes groundbreaking surgery.

Two-year-old Indonesian chain smoker; young man with facial tumor may not survive surgery; seven-year-old twins attached at the head.

A teenager who has been hiding a rare condition undergoes surgery, doctors attempt to diagnose a young girl born with dark hair covering her entire body and a man with tree like growths encasing his hands and feet seeks treatment.

Triplets born with a rare condition need surgery or their brains could be crushed; a boy has legs that have become so large he is unable to move; a soccer star who was born without feet.

Young Dominican woman cries blood; world's fattes child has insatiable appetite; young girl trapped behind werewolf's face.

A woman suffers crippling sinus pains.

A young man has strange growths; toddler rapidly gains weight.

A baby is born with a series of defects; deadly sore throat.

Constant respiratory infections and an inability to grow; mysterious spasms and back pain overcome a man's life.

Harry is born healthy but his body starts transforming; Sadie is on the brink of starvation.

A girl is born with shocking deformities; a college student suffers from fluid around his heart and lungs.

A baby is born with a series of defects; deadly sore throat.

Constant respiratory infections and an inability to grow; mysterious spasms and back pain overcome a man's life.

Harry is born healthy but his body starts transforming; Sadie is on the brink of starvation.

A girl is born with shocking deformities; a college student suffers from fluid around his heart and lungs.

A woman suffers crippling sinus pains.

A young man has strange growths; toddler rapidly gains weight.

The staff of Wishard Memorial Hospital treat accident victims and victims of violence.

Trauma patients flood the Tampa General Hospital during Gasparilla Day - the city's version of Mardi Gras.

Shooting victim; teen is severely injured.

A gunman opens fire outside a strip club; a street performer's magic trick goes horribly wrong; BMX superstar T.J. Lavin's routine jump has a shocking outcome.

A maintenance worker falls from an iconic hotel sign; a rat bite has horrifying implications for its trainer and a plane crashes on a residential street.

A shootout leaves a police officer clinging to life; a cowboy and cupid help a she-devil in distress; a zip-line guide falls 80 feet to the canyon floor.

Doctors retrieve a stolen Rolex from a very private spot; a pick-up turns deadly when a cabbie is shot multiple times; a dirt-bike accident in the desert leaves a 52-year-old thrill-seeker clinging to life.

A brutal assault could end a star athlete's career, a 28-year-old man is hit in the head by a flying baseball bat; and a Vegas chef falls asleep with a loaded gun.

Paramedics rescue a 25-year-old man from a burning vehicle; an out-of-control car smashes into the patio of a restaurant; and a Vegas ventriloquist narrowly escapes death in a head-on collision.

A man gets a wire embedded in his heart; three year old swallows magnets; woman has pencil in her brain; man has a five centimeter splinter removed from eye.

A car accident leaves a pole penetrating a man's mouth and neck, a man accidentally eats a sewing needle, a 75-year-old man finds out he has had a nail in his face.

A woman is impaled on an iron spike; a man spears his friend on a fishing trip; an elderly gardener's shears are lodged in his eye.

A man is impaled on a fence post; a farmer has an object lodged in his brain; a woman is skewered on a hooked pole when she feeds the birds.

A woman gets a Christmas tree imbedded in her neck; a boy out fishing almost chokes on a barb; a man is filled with enough air to fill 1000 balloons; learn how they survived.

Laura's collection has spiraled into a compulsion; during her clean-up, a house fire ignites.

Gary's house is so full that he is forced to sleep outside on a makeshift bed.

Kathy's extreme hoarding forced her 12-year-old son to move out of their home.

Severe debt and clutter has Dennis moments away from losing everything; Monte's clothing hoard has destroyed a relationship with her son.

Laura's collection has spiraled into a compulsion; during her clean-up, a house fire ignites.

Gary's house is so full that he is forced to sleep outside on a makeshift bed.

Kathy's extreme hoarding forced her 12-year-old son to move out of their home.

Severe debt and clutter has Dennis moments away from losing everything; Monte's clothing hoard has destroyed a relationship with her son.

Cary's paralyzing obsession with Elvis memorabilia has left his New York City apartment virtually uninhabitable.

Randy is being forced to leave the apartment he has lived in for more than 20 years.

Diane has thousands of tumors all over her body; Will fears his shoulder lump will be ripped open; Anthony gets his lump examined; Kal Elle detests her hideous varicose veins.

Pop-up facts and behind-the-scene secrets are revealed; Louis is covered in scaly, dry skin that makes him feel like an alligator; Irais' children are bullied because of the growth on her head; Johnny has a stubborn lump on his back.

Pop-up facts and behind-the-scene secrets are revealed; Belinda's lump on her neck causes her immobility; Nicole needs her armpit lump removed; Adela's chest and back are covered in wisdom spots; Nick foolishly removes a lipoma at home.

April is covered with disfiguring bumps on her arms; Genner, from the Philippines, needs help with his bumpy nose.

Jen has growths on her ears that cause her depression, pain and vertigo; Juliet is under distress because of the bumps on her neck and chest; Gerald has a lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about his finger bump; Vinnie has a large birthmark on his neck; Leta has a lump on the back of her thigh.

Taylor has a large bump at the base of her spine; John jokes about hip lump, but it's no laughing matter; Noelle wants her stretched ears repaired; new pop-up facts.

All-new juicy pop-up facts and behind-the-scenes secrets.

Inoke has a possibly life-threatening bulge on his shoulder; Delano returns with his back lump.

Leonard has a bump on his arm that looks like it's breaking through the skin; Brandon has lumps on his head; Jess gets a lump on her butt after falling down the stairs.

Pop-up facts and behind-the-scenes secrets are revealed; Dr. Sandra Lee assists Matt with the tumors growing all over his body; Yamileth hasn't pursued her dreams because of her neck lump; Jennifer has a unicorn bump on her forehead.

Facts and behind-the-scenes secrets; Melissa tries to cover a lipoma with a sweatshirt; Tyler's fear of cancer keeps him from having his head lumps diagnosed; Amber's ear keloids have taken control of her life.

Gerard has nearly 100 lumps, varying in size, all over his body; no one has been able to help Gina with her bloody lesions; Eric calls the large bump on his head his on-off button.

With new pop-up facts and behind-the-scenes secrets; Dr. Lee assists Ronen with the mysterious lump above his knee; Amber suffers from a debilitating skin disease, Sandy has a neck lump; Kristy's eyelid cyst is ruining her life.

All new juicy pop-up facts and behind-the-scenes secrets finally revealed; a woman suffers from clusters of face bumps, and a man has a growth that dangles near his genital area; a patient's nose lump makes it difficult for him to breathe.

With pop-up facts and behind-the-scenes secrets; a patient returns to find out if a suspicious eye growth is skin cancer; a woman hopes Dr. Lee can help her with clusters of lumps; a man suffers from a giant forehead lump.

All new pop-up facts and behind-the-scenes secrets; Barbara's back lump becomes more noticeable after she loses 131 pounds; Bob has painful back bumps; Hilda struggles with bumps on her eyelids; Art covers his head bumps with hats.

With pop-up facts and behind-the-scenes secrets; Dr. Lee helps Lisa, who has a horn growing out of the back of her head; Victor has a bulbous chest lump; Chuck has a Popeye-shaped arm bump; two brothers have matching lumps.

All new juicy pop-up facts and behind-the-scenes secrets finally revealed; a woman suffers from clusters of face bumps, and a man has a growth that dangles near his genital area; a patient's nose lump makes it difficult for him to breathe.

With pop-up facts and behind-the-scenes secrets; a patient returns to find out if a suspicious eye growth is skin cancer; a woman hopes Dr. Lee can help her with clusters of lumps; a man suffers from a giant forehead lump.

All new pop-up facts and behind-the-scenes secrets; Barbara's back lump becomes more noticeable after she loses 131 pounds; Bob has painful back bumps; Hilda struggles with bumps on her eyelids; Art covers his head bumps with hats.

With pop-up facts and behind-the-scenes secrets; Dr. Lee helps Lisa, who has a horn growing out of the back of her head; Victor has a bulbous chest lump; Chuck has a Popeye-shaped arm bump; two brothers have matching lumps.

Gerard has nearly 100 lumps, varying in size, all over his body; no one has been able to help Gina with her bloody lesions; Eric calls the large bump on his head his on-off button.

With new pop-up facts and behind-the-scenes secrets; Dr. Lee assists Ronen with the mysterious lump above his knee; Amber suffers from a debilitating skin disease, Sandy has a neck lump; Kristy's eyelid cyst is ruining her life.

An urgent care physician must think outside the box to care for two emergencies at once; a woman with abdominal pain receives an unexpected diagnosis; a yoga instructor has a dangerously high temperature for no obvious reason.

A patient gets brought in with a live shark clamped onto his thigh, and he wants to save the shark; complications arise for a woman with a life-threatening condition; a mysterious condition causes a man to pass out.

Police officers bring in a criminal that is comatose; a man found passed out in the snow with no jacket or shoes arrives in the ER and a doctor is faced with a family emergency on her day-off.

A fishing lure embedded in a man's face turns out to be the least of his problems; a pair of unconscious teenagers get brought to the ER, where dramatic family secrets come out; an ER technician collapses and refuses traditional medical treatment.

A man's itchy rash turns out to be more than just poison oak; a young woman bleeds profusely from the inside of her lip, but there is no obvious cause; a family of three is admitted as car accident victims, but the doctor makes a shocking discovery.

Two separate car crash victims are brought to the ER in their underwear; a woman is acting delusional and refuses to allow the ER staff to touch her; a doctor struggles to diagnose a dehydrated and nauseous 10 year old.

A teenage girl is impaled through the neck on an iron fence; a patient is convinced he's turning into a vampire; a first-year attending physician stands up to a room full of senior specialists to save the life of a critically ill pregnant woman.

The ER is a crime scene when a woman's belly pain is caused by smuggled narcotics; a doctor is mystified by heart attacks occurring the same day in the same family; strange markings on the body of a car crash victim lead to the cause of the accident.

Two seemingly unrelated gunshot wounds lead to a bizarre night in the ER; a senior nurse unravels at the sight of a critical patient, and reveals a shocking secret; a patient's grave symptoms mysteriously disappear whenever the doctor touches him.

A woman comes in with a piece of rebar impaling her thigh; a man brings his girlfriend into the ER for an STD workup; an ER doctor confronts a woman's prejudiced colleagues.

A man passes out from abdominal pain; a woman helps solve the mystery of her estranged father's deadly symptoms; a group of delirious Civil War re-enactment soldiers arrives in the ER.

A wrist fracture turns into a medical mystery; two fishermen get stuck on the same lure; a cheerleader with a sprained finger nearly dies of an unexpected cause; a power outage foils the ER team's effort to get a dying patient to the O.R.

The hospital is locked down when a nurse is shot in the ER; medics rush a bride from her wedding who is in an unexplained altered mental state; a doctor must perform a risky intervention to save the life of a teenage girl.

A teen football player suffers a stroke; a doctor remembers his first major trauma in the 1970s; a doctor tries to figure out what causes a patient's abdominal pain.

A doctor with a severe bee allergy is stung while treating a critical patient who's been stabbed in the eye; a man comes into the ER after slitting his own throat; a paramedic becomes a patient when she's struck by a mysterious illness.

A surgical resident puts her training to the test when a mugging survivor arrives with two bullet wounds.

An alligator snapping turtle is clamped to a man's neck; an impending hurricane; impaled by a chainsaw.

Two skydivers are impaled by a fence post; multiple patrons stop breathing; a bride's finger gets stuck in a make-up jar.

A doctor with a severe bee allergy is stung while treating a critical patient who's been stabbed in the eye; a man comes into the ER after slitting his own throat; a paramedic becomes a patient when she's struck by a mysterious illness.

A surgical resident puts her training to the test when a mugging survivor arrives with two bullet wounds.

An alligator snapping turtle is clamped to a man's neck; an impending hurricane; impaled by a chainsaw.

Two skydivers are impaled by a fence post; multiple patrons stop breathing; a bride's finger gets stuck in a make-up jar.

The hospital is locked down when a nurse is shot in the ER; medics rush a bride from her wedding who is in an unexplained altered mental state; a doctor must perform a risky intervention to save the life of a teenage girl.

A teen football player suffers a stroke; a doctor remembers his first major trauma in the 1970s; a doctor tries to figure out what causes a patient's abdominal pain.

Kinah's addiction to eating toilet paper threatens her health, and her relationships are also on the line; Nathaniel has taken his love of cars to the extreme; Lisa eats cat hair - and she just cannot get enough.

Nick and Aubrey's addiction to drinking urine has Nick's mom extremely concerned; Karmello's life has gained new meaning since her addiction to illegal butt injections; Lori's addiction to sleeping with her blow dryer might be affecting someone else.

Tyler's addiction to smelling tuna is getting in the way of finding love; Lacey's addiction to plastic surgery and her cup size has grown; after mourning the loss of her record-setting fingernails, Ayanna still has an addiction.

Brittany's addiction to eating car seat foam forces her family to intervene; Lauren has put her addiction to bodybuilding behind her but has found a new obsession; Asha's addiction to her long locks remains strong, but her health remains in jeopardy.

Foxy's addiction to having enormous breasts has brought her fame, but her friends feel it is also endangering her health.

Weston loves eating raw meat, but his mom is worried it could lead to major health problems; Rachel breastfeeds her husband, Alexander, but it's upsetting to their family and friends; pillow addict Tamara meets car lover Nathaniel.

A rock singer discovers she is pregnant and in labor after smoking and drinking.

A British woman, 57, undergoes a harrowing journey to conceive, but suffers a miscarriage.

A college student finds out she is pregnant when she is rushed to the emergency room.

A woman finds out she is pregnant in an emergency room.

A woman goes into labor in her bathtub.

A 19-year-old discovers she is pregnant in the middle of the night.

A high-school student thinks that her weight gain and fatigue are from eating poorly and working too much.

After failing two pregnancy tests, a woman is shocked to learn the truth about her symptoms; a woman gets a surprise after having gastric bypass surgery.

An unknowing mother goes into labor in her bathroom; a woman's water breaks years after being told that she is unable to get pregnant.

A teenager believes that she is unable to bear children after having an aggressive chemotherapy treatment; a nursing student learns she is pregnant after an emergency appendectomy.

Kit and Jourdan's fairytale wedding turns into a fight for the groom's life; Frank and Jen's nuptials are derailed when they get kidnapped and taken for ransom; Gus and Jen's sand ceremony takes on a whole new meaning.

Jon and Christine's wedding takes a scary turn when the bride suddenly goes blind; Frank and Patricia plan a picture perfect wedding only to capture a moment that ends in the ER; everyone at Landon and Jamie's wedding falls mysteriously ill.

Erik and Ashley's pirate-themed wedding turns into a treasure hunt for the ER.; Taylor and Ellie's plans go up in smoke when their walk down the aisle becomes a sprint toward safety; Connor and Sabrina's wedding day gets quite literally swept away.