Kirsten is close to losing all her mobility, and while she's trying to control of her obesity, she's also in danger of losing her troubled son.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Half of Mary's body is a size 18 while the other half is a size 8; Anthony's cyst is in the area called the "Triangle of Death;" Shane wants to get a lump off his back; Brandi is anxious about getting a lump removed from her chest.

Belinda's lump on her neck causes her to basically be immobile; Nicole won't get married until she gets her armpit lump removed; Adela's chest and back are covered in wisdom spots; Nick foolishly removes a lipoma at home and now needs Dr. Lee.

Diane has tumors all over her body that have ruined her life; Will fears his shoulder lump will be ripped open at work; Anthony's daughters force him to get his lump examined; a woman detests her hideous varicose veins.

Taylor has a large bump at the base of her spine that is far more dangerous than she realizes; John jokes about his hip lump, but it's no laughing matter; Noelle had her ears stretched as a teen, but now wants them repaired.

Louis is a veteran who is covered in scaly, dry skin that makes him feel like an alligator; Irais's kids are bullied because of the embarrassing growth on her head; Johnny has been living with a stubborn lump on his back for too long.

Patrick's nose is covered by huge bumps, and he can barely breathe; Aziza and Lauren are friends who bonded over their matching wrist lumps; Joe has a mound in the middle of his forehead that looks like a third eye.

April is covered in bumps that disfigure her arms; Genner flies all the way from the Philippines to have Dr. Lee help with his bumpy nose; Chris suffers from psoriasis that nearly covers his body and a bump on his head.

Matt has a skin condition that causes tumors to grow all over his body; Yamileth hasn't pursued her dreams because of the lump on her neck; Pat is covered with dark spots from her neck to her abdomen; Jennifer has a unicorn bump on her forehead.

Amber has hundreds of tumors on her face; Antonio has a mound on his spine and is afraid it might be impossible to remove; sisters Cheri and Janice both suffer from possibly matching lumps; Tatiana has an embarrassing bump on her butt cheek.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Taylore is a beautiful young woman who has unsightly elf-like bumps on her ears; Jose never goes out because of the baseball-sized lump on his head; Ken is covered in painful bumps that make it difficult to do everyday things.

Josh has a large knot on his head resulting from a car crash from 18 years ago; Brittney is covered in mysterious bumps; TJ has a hard, curious lump protruding from his side; Luis has a bump on his shoulder and his daughters fear it's dangerous.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Leonard has an alarming bump hanging off of his arm that looks like it's breaking through the skin; Brandon has several lumps on his head that make him fearful for his life; Jess gets a noticeable lump on her butt after falling down the stairs.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Leonard has an alarming bump hanging off of his arm that looks like it's breaking through the skin; Brandon has several lumps on his head that make him fearful for his life; Jess gets a noticeable lump on her butt after falling down the stairs.

Extreme hoarder Floyd must clean his home or risk losing his 3-year-old son, Charlie.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

Gary's house is so full that he is forced to sleep outside on a makeshift bed.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

Featuring the 10 most extreme hoards from Hoarding: Buried Alive.

A man injured by a boat propeller; a deadly chain of events; the ER comes to a standstill.

Two gunshot victims; a jogger goes into a coma; the ER staff becomes detectives.

A newlywed's hand gets stuck in a kitchen appliance; a student with an injury down under; a heavy drinker has complications.

A college student's face covered in a plaster mask; a stroke patient's heart keeps stopping and restarting without intervention.

A patient's violent outbursts; a man's heart fails; a patient with severe burns prays for a miracle.

A patient gets drunk to save his life; a patient is stiff after a fall; a patient tasered by the police; a boy impaled by a bottle rocket in the neck.

A man with half a torso learns if his rare bone-eating disease is back; a young girl undergoes surgery to stop her facial tumor from choking her; a boy is born with half a face.

A man with cold-like symptoms loses his limbs and lips; a young girl has a prematurely fused skull; a boy with brittle bones and a rare skin condition gets life-changing surgery; a woman suffers from a disfiguring birthmark; with bonus content.

A woman suffers from cyclical vomiting syndrome; a man with warts all over his body searches for cures; a girl fights for a surgery that could allow her to speak for the first time; with bonus content.

A man's maimed hand is sewn into his stomach to avoid amputation; a young girl is born with a deformed mouth and jaw; a boy's organs are inverted; a man who can't smile finds love; with bonus content.

A boy tries to get his balloon facial tumor removed; a woman who is allergic to UV light must take precautions; a woman fears her birthmark is still growing; a boy with undeveloped legs walks on all fours; with bonus content.

A boy who can't stop eating undergoes a series of operations to save his life; a young man who is more than 7-feet tall learns if he's still growing; a boy is born without eyes; Irish twins' muscles and flesh turn to bone; with bonus content.

A woman suffers from cyclical vomiting syndrome; a man with warts all over his body searches for cures; a girl fights for a surgery that could allow her to speak for the first time; with bonus content.

A man's maimed hand is sewn into his stomach to avoid amputation; a young girl is born with a deformed mouth and jaw; a boy's organs are inverted; a man who can't smile finds love; with bonus content.

A boy tries to get his balloon facial tumor removed; a woman who is allergic to UV light must take precautions; a woman fears her birthmark is still growing; a boy with undeveloped legs walks on all fours; with bonus content.

A boy who can't stop eating undergoes a series of operations to save his life; a young man who is more than 7-feet tall learns if he's still growing; a boy is born without eyes; Irish twins' muscles and flesh turn to bone; with bonus content.

A man with half a torso learns if his rare bone-eating disease is back; a young girl undergoes surgery to stop her facial tumor from choking her; a boy is born with half a face.

A man with cold-like symptoms loses his limbs and lips; a young girl has a prematurely fused skull; a boy with brittle bones and a rare skin condition gets life-changing surgery; a woman suffers from a disfiguring birthmark; with bonus content.

At age 58, Rose had almost given up and eaten herself to death, but it turned out her family needed her too much for her to go; now she has more than 400 pounds to lose if she wants to get healthy for them, and she's determined to do it.

A mother of two who is too ashamed of her size to be seen with her children; she is committed to regaining her confidence and being a proud mother.

Susan, 37-year-old woman, has never lived on her own because of her weight, is finally seeking help to get out on her own.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden; Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live.

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

With the support of his fiancé, Kathryn, Robert turns to Dr. Nowzaradan in a final, desperate attempt to save his life; he tries to reverse a lifelong food addiction that has left him bed-bound, saddled with grotesque lymphedema, and nearly 900-lbs.

After losing 250lbs, Nikki is on her way to skin surgery, but when a close friend dies from weight loss surgery, Nikki's progress is derailed by fears.

With her weight spiraling, Stephanie needs her mom's help to care for her three kids; she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

With her weight spiraling, Stephanie needs her mom's help to care for her three kids; she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

After losing 250lbs, Nikki is on her way to skin surgery, but when a close friend dies from weight loss surgery, Nikki's progress is derailed by fears.

Identical twins enlist Lisa's help to unlock the mystery of why they were placed for adoption; Chris hopes to fulfill the wishes of a deceased father by tracking down the first-born son he and his wife had placed for adoption.

A surprisingly troubled outcome with her birth mother prompts an adoptee to find her father, leading to life-changing truths; a woman tries to repair relationships with the biological father she just met and the father who raised her.

A woman enlists Lisa's help to find her birth mother, but unearths a 40-year-old secret in the process.

Chris and Lisa join forces in an attempt to solve the childhood mystery of why a woman was separated from her birth family at the age of two.

After a joyful reunion with the daughter he was forced to give up, Jon now struggles to maintain their relationship; high school sweethearts who placed their son up for adoption happily meet his adoptive parents and participate in his wedding.

Lisa hopes that locating a man's biological mother will finally allow him to overcome his lifelong struggle with abandonment; Chris locates a woman's only child and delivers the difficult details of her daughter's birth story.

Twins Kandi and Brandi have a combined weight of over 1,100 pounds and fear losing each other to obesity, so they decide to make a change together.

Erica regrets not keeping a promise to her mom and hopes her siblings will help, but they're reluctant based on her past failures.

When Travis gets too big to walk down the aisle, he promises to give his wife a proper wedding; he gains more weight, leaving Dr Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.

For Milla Clark, after three years and five surgeries, success would mean beating the odds and becoming one of Dr. Nowzaradan's most impressive weight-loss patients, but failure would mean slipping back to the bedbound life.

Milla is dependent on her children and seeks to lose enough weight to be able to walk; Charity is mired in a deep depression, while her daughter, Charly, battles a food addiction; they strive to turn things around and reach their goal weight.

Thederick has become housebound from eating and only goes outside to greet the ice cream man; after a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.

Milla is dependent on her children and seeks to lose enough weight to be able to walk; Charity is mired in a deep depression, while her daughter, Charly, battles a food addiction; they strive to turn things around and reach their goal weight.

Thederick has become housebound from eating and only goes outside to greet the ice cream man; after a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.

For Milla Clark, after three years and five surgeries, success would mean beating the odds and becoming one of Dr. Nowzaradan's most impressive weight-loss patients, but failure would mean slipping back to the bedbound life.

Two brothers navigate a painful past as they search for the family they've longed for their entire lives, and their journey reopens decades-old family mysteries about their birth mother, twin siblings and a baby who was only rumored to exist.

Lisa meets a woman who was left on a curb by her mother when she was just four years old; Chris uncovers stunning information for a woman searching for her family that leads to an unexpected reunion.

A man who always longed for a sibling stumbles upon a shocking family murder; Lisa meets a woman eager to find her biological mother, but she also finds information that changes her view of the past.

A woman longs to meet her birth father, a man she credits for saving her life during a difficult childhood, even though they never met; a desperate man hopes Lisa can end a 57-year search for his infant sister, who he never stopped loving.

A gunman opens fire outside a strip club; a street performer's magic trick goes horribly wrong; BMX superstar T.J. Lavin's routine jump has a shocking outcome.

A maintenance worker falls from an iconic hotel sign; a rat bite has horrifying implications for its trainer and a plane crashes on a residential street.

A shootout leaves a police officer clinging to life; a cowboy and cupid help a she-devil in distress; a zip-line guide falls 80 feet to the canyon floor.

Doctors retrieve a stolen Rolex from a very private spot; a pick-up turns deadly when a cabbie is shot multiple times; a dirt-bike accident in the desert leaves a 52-year-old thrill-seeker clinging to life.

A brutal assault could end a star athlete's career, a 28-year-old man is hit in the head by a flying baseball bat; and a Vegas chef falls asleep with a loaded gun.

Paramedics rescue a 25-year-old man from a burning vehicle; an out-of-control car smashes into the patio of a restaurant; and a Vegas ventriloquist narrowly escapes death in a head-on collision.

A surgical resident puts her training to the test when a mugging survivor arrives with two bullet wounds.

A teen football player suffers a stroke; a doctor remembers his first major trauma in the 1970s; a doctor tries to figure out what causes a patient's abdominal pain.

A man's face and body suddenly double in size; a young woman is burning up from the inside out after a day at the beach; a grumpy old man nearly dies before revealing an emotional secret.

A pianist's finger goes missing after getting accidentally sawed off; a man's pacemaker threatens to kill him; a man behaves bizarrely.

A pregnant woman is shot in the abdomen; a doctor is the victim of a car burglary; a storm is preventing a patient's life-saving surgery.

A woman risks losing her finger after trying on an ill-fitting engagement ring; a body builder can't breathe and doctors are shocked to discover why; a gunshot victim.

A Halloween zombie with a problem below the belt mystifies doctors; two unconscious men are involved in an accident, a doctor makes a mistake that amazingly explains a patient's condition.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change; a pregnant woman's life-threatening symptoms need urgent treatment.

A pregnant woman is shot in the abdomen; a doctor is the victim of a car burglary; a storm is preventing a patient's life-saving surgery.

A woman risks losing her finger after trying on an ill-fitting engagement ring; a body builder can't breathe and doctors are shocked to discover why; a gunshot victim.

A Halloween zombie with a problem below the belt mystifies doctors; two unconscious men are involved in an accident, a doctor makes a mistake that amazingly explains a patient's condition.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change; a pregnant woman's life-threatening symptoms need urgent treatment.

A man's face and body suddenly double in size; a young woman is burning up from the inside out after a day at the beach; a grumpy old man nearly dies before revealing an emotional secret.

A pianist's finger goes missing after getting accidentally sawed off; a man's pacemaker threatens to kill him; a man behaves bizarrely.

When a mother takes her sick son to the ER, nothing can prepare her for the scene that greets her as she finds that the entire town is sick; the Public Health Commission rushes to find what is causing a deadly E coli outbreak.

A church congregation in New Sweden, Maine becomes dangerously ill after a Sunday service. Doctors must rush to find an answer on what is causing 12 people to become ill and another to die.

A brain ailment strikes a 22-year-old woman.

After a night of celebration in New York City an out-of-town couple soon finds that they are dangerously ill; further investigation into the cause returns shocking results.

Eight-year-old Joshua Wooten is rushed to the ER after his mother finds him collapsed on the bedroom floor. When it is found that Joshua is struggling to breathe and his health continues to decline, doctors are left baffled at what is the cause.

A successful businesswoman suddenly seems to become possessed by demons; a young college student battles monstrous pain when she grows fingernails out of her hair follicles.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

A woman has seizures whenever she hears her favorite pop tunes; a young athlete loses all his body fat and almost starves to death.

A man faces amputation when a mystery disease turns his extremities black; a young woman develops paralyzing fears about ordinary objects.

A beautiful model turns into a raging monster and starts attacking everyone around her; a man's life is nearly destroyed when he can't stop burping.

A woman's life is ruined by extreme sweating day and night; a young teacher prays to stop living when he feels invisible bugs crawling all over him.

Mysterious symptoms appear for a man who recently underwent minor surgery.

A new baby is plagued with health problems.

Doctors can't pinpoint the cause of the array of ailments a woman has been suffering from for more than 50 years.

A woman who successfully gives birth after two miscarriages faces challenges.

A boy has infrequent bowel movements; a bodybuilder discovers a painful lump in her jaw.

A baby develops a bulging forehead and eye color changes; a teen suffers hand pain during swim practice.

Doctors can't pinpoint the cause of the array of ailments a woman has been suffering from for more than 50 years.

A woman who successfully gives birth after two miscarriages faces challenges.

A boy has infrequent bowel movements; a bodybuilder discovers a painful lump in her jaw.

A baby develops a bulging forehead and eye color changes; a teen suffers hand pain during swim practice.

Mysterious symptoms appear for a man who recently underwent minor surgery.

A new baby is plagued with health problems.

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

Pauline is 51-years-old and nearly 700 pounds; her addiction to food has taken over the life of her son and primary caretaker.

At 24-years-old, Bettie Jo is on her way to reaching 700 pounds and relies on her husband for her basic needs.

Steven Assanti weighs nearly 800 pounds and his brother Justin almost 600 pounds, and although they can't stand each other, their father packs up the family to travel across the country and seek help.

After a year on a weight loss program, Steven remains completely non-compliant and Justin focuses on a new career instead of his diet, but time is quickly running out for surgery.

Steven's dysfunction escalates, pushing his relationship with Dr. Nowzaradan; his brother Justin takes the leap to go to Houston to finally accept help.

Surgery enables Teretha to return to family in Detroit, but it soon threatens to undo all her progress; Chad is back on the road, but his old diet is a risk.

At nearly 1,000 pounds, Samantha is dangerously close to dying; to make matters worse, she's paid to eat by making videos online; if Samantha doesn't overcome her toxic relationship with food, she worries she will leave her daughter motherless.

A teenage girl is impaled through the neck on an iron fence; a patient is convinced he's turning into a vampire; a first-year attending physician stands up to a room full of senior specialists to save the life of a critically ill pregnant woman.

The ER is a crime scene when a woman's belly pain is caused by smuggled narcotics; a doctor is mystified by heart attacks occurring the same day in the same family; strange markings on the body of a car crash victim lead to the cause of the accident.

Two seemingly unrelated gunshot wounds lead to a bizarre night in the ER; a senior nurse unravels at the sight of a critical patient, and reveals a shocking secret; a patient's grave symptoms mysteriously disappear whenever the doctor touches him.

A woman comes in with a piece of rebar impaling her thigh; a man brings his girlfriend into the ER for an STD workup; an ER doctor confronts a woman's prejudiced colleagues.

A teenage girl is impaled through the neck on an iron fence; a patient is convinced he's turning into a vampire; a first-year attending physician stands up to a room full of senior specialists to save the life of a critically ill pregnant woman.

The ER is a crime scene when a woman's belly pain is caused by smuggled narcotics; a doctor is mystified by heart attacks occurring the same day in the same family; strange markings on the body of a car crash victim lead to the cause of the accident.

Two seemingly unrelated gunshot wounds lead to a bizarre night in the ER; a senior nurse unravels at the sight of a critical patient, and reveals a shocking secret; a patient's grave symptoms mysteriously disappear whenever the doctor touches him.

A woman comes in with a piece of rebar impaling her thigh; a man brings his girlfriend into the ER for an STD workup; an ER doctor confronts a woman's prejudiced colleagues.

At nearly 1,000 pounds, Samantha is dangerously close to dying; to make matters worse, she's paid to eat by making videos online; if Samantha doesn't overcome her toxic relationship with food, she worries she will leave her daughter motherless.

Tony has large growths on his nose that impair his breathing; Kevin has a bump in his jawline that is a lady deterrent; Marie has an unsightly lump on her forehead that makes her a hermit; Tommy's leg bump makes it difficult for him to work.

Gerard has nearly a hundred lumps varying in size all over his body; Gina has bloody lesions all over; Eric has a large bump on his head that he calls his on and off button.

Traci's confidence has been destroyed after years of bullying from the bumps on her face; Ravon has a unique dangling growth on his leg; David has a large lump.

David is back to see Dr. Lee after she spots a suspicious growth under his eye; Nicole is depressed because of the bumps all over her neck; Steve has a noticeable lump on his forehead; Allen has a growth on his biceps but is terrified of doctors.

Tim has a massive growth on his back that affects his ability to work and socialize; Daniel has debilitating psoriasis that covers most of his body; Gloriana and Yolanda are a mother and daughter duo who have bonded over their bumps.

Inoke has a huge, possibly life-threatening bulge on his shoulder; Delano returns with his back lump after Dr. Lee removed a liter of fluid from it; Reed has hundreds of bumps on his chest that burst and leave nasty scars.

With pandemic safety protocols in place, Dr. Lee reopens her office; Monica has a large birthmark growing on the side of her face; Jackie has a melon-sized lump on the back of her shoulder; Reginald has large, rare growths on the back of his head.

Dr. Lee tries to provide the help Reginald needs to remove the large, rare growths on the back of his head; Che'Re has a prominent bump on her face that has put her in a dark place; Juan has several painful boils on the back of his neck.

Dennis has several giant growths on the back of his head; Juan has a rare condition he hopes Dr. Lee will understand; Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps.

Audrey pops the painful bumps that cover her body so she can feel relief; Felicia has a peculiar-looking dark growth on her forehead; Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat.

John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.

Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.

Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove.

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.

Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove.

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

Cousins Casey, Amanda, Amy and Ed are morbidly obese; when Amanda decides to have bariatric surgery, the family considers doing the same.

Amanda undergoes bariatric surgery in the hopes of losing enough weight to treat her cancer; Casey meets with Dr. Procter and is told he'll die if he doesn't lose weight; the family has a pool party and Casey confronts Ed over his name-calling.

Casey reaches a boiling point with his parents when they blame his morbid obesity on video games; Amanda starts having pains post-surgery that send her to the E.R.; Amy makes major lifestyle changes in the hopes of being approved for surgery.

The family comes together to support Amy on her tough road to recovery; as Ed's surgery rapidly approaches, his daughters start expressing their concerns; Casey starts questioning surgery more than ever after watching Amy go through post-op.

The family's fight during Ed's surgery leaves Casey questioning whether he should go through with the surgery himself; Amy panics when she learns how difficult the Spartan Race will be; Amanda undergoes testing to see if her cancer has spread.

It's the moment of truth as Casey learns if he has been approved for life-saving surgery; Amanda has huge news regarding her cancer; Amy attempts a hellacious Spartan Race; the King family throws a party to reveal their shocking new looks.

A mother tries to protect her children from their father's hoard; an artist chooses frog, penguins and banana peels over her boyfriend.

Maggie's piles of collections is putting her son's life at risk; Bob's passion for swimming pool parts is pushing his family to the brink.

Traci is pregnant and desperate to move back home, but it's filled floor to ceiling with her mother's stuff.

Kathleen discovers a hoard of mice living in her kitchen; spending the night in a hoard might be the end of a marriage before it even begins.

Medical responders were not able to get in Renee's front door after she had fallen unconscious in her home.

Rick tries to salvage his cluttered home that was nearly destroyed in a house fire; Linda must get her house up to code in 60 days or she will be on the streets.

A man seeks to get the fatty growths on his chest removed; a boy's eye falls out of his skull; a man with giant facial keloids goes under the knife one last time; a young boy lives with an agonizing skin condition; with bonus content.

A man's body blows up like a balloon after a diving accident; a man seeks to get his giant leg tumor removed; a woman who lost the middle of her face to cancer tries to get her confidence back; a man drinks five gallons of water a day to stay alive.

The world's fattest man undergoes weight loss surgery; a woman learns why she can't feel physical pain; twins joined at the head learn if they can be separated; a young boy born without limbs relies on constant transfusions; with bonus content.

A young girl with a crippling leg defect undergoes life-changing surgery; a man is born with his heart outside his rib cage; a karate champion battles a rare skin disorder.

A girl with a paralyzed face tries to find a new smile; a man with a crippling skin condition lives life on his own terms; a man with a form of dwarfism fears his back pain will stop him from running marathons.

Parents of a 44-pound baby seek to understand why their son can't stop eating; a man travels to get his giant neck tumor removed; a young girl lives trapped inside her body; a woman with a severe chemical allergy can't go outside.

The world's fattest man undergoes weight loss surgery; a woman learns why she can't feel physical pain; twins joined at the head learn if they can be separated; a young boy born without limbs relies on constant transfusions; with bonus content.

A young girl with a crippling leg defect undergoes life-changing surgery; a man is born with his heart outside his rib cage; a karate champion battles a rare skin disorder.

A girl with a paralyzed face tries to find a new smile; a man with a crippling skin condition lives life on his own terms; a man with a form of dwarfism fears his back pain will stop him from running marathons.

Parents of a 44-pound baby seek to understand why their son can't stop eating; a man travels to get his giant neck tumor removed; a young girl lives trapped inside her body; a woman with a severe chemical allergy can't go outside.

A man seeks to get the fatty growths on his chest removed; a boy's eye falls out of his skull; a man with giant facial keloids goes under the knife one last time; a young boy lives with an agonizing skin condition; with bonus content.

A man's body blows up like a balloon after a diving accident; a man seeks to get his giant leg tumor removed; a woman who lost the middle of her face to cancer tries to get her confidence back; a man drinks five gallons of water a day to stay alive.

Lupe has spent the last 10 years in bed and is totally dependent on her husband, prompting a cross-country move that could save her life or end up backfiring.

An overweight woman struggles with flesh-eating bacteria and butterfly shaped fat deposits; unexpected news threatens her weight loss journey.

Laura has used food to cope with her emotions; she is confined to a wheelchair and relies on an oxygen tank to breathe and her husband and mother to survive.

Syreeta thinks that anyone trying to help has an ulterior motive, but she's gotten so big she desperately needs help; she's learning to let down her guard for her husband, but weight-loss surgery will be tough if she can't learn to trust the surgeon.

At 670 pounds, Ashley, who lives in her parents' home with her husband, decides she must make a drastic change to save her life and her marriage.

Cynthia, a single mother focused on raising five kids, comes to realize what her death would mean for their future.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

Tanisha weighs around 600-lbs and she's desperate to survive for her kids and avoid her mother's tragic fate of dying at age 50 from super obesity; now at 32, her future looks grim if she doesn't make a drastic change to save her life.