After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon to over 500 pounds; she has become a hermit and hopes to restart her life so she can better care for her son, Zachary.

Unable to stand for more than a short period of time, Karina's weight places a burden on her parents and drives a wedge between her and her sister.

A 16 inch Nepalese elder lobbies to get the record for world's smallest man.

Boys Giovanni and Owen share the rare condition Schwartz Jampel Syndrome, which permanently and painfully contracts their muscles; the two share hardships and triumphs, and strike up a friendship.

Tiffany and Destiny both live with the rare disease Osteogenesis Imperfecta, which causes brittle bones, and set out on a life changing journey to meet each other.

Bobbi and Kenny have skin that painfully grows in thick scales due to the rare condition Lamellar Ichthyosis.

Getting too hot can be fatal for twins Andrew and Brandon, who meet Josh, a fellow sufferer of Ectodermal Dysplasia.

Tiffany and Yajaira have Jarcho Levin Syndrome, which malformed their ribs and spines during infancy.

Born with Goldenhar Syndrome, Austin and Elena have been bullied for looking different, and feel isolated from other kids.

A man just 16 inches tall campaigns for the record of smallest man; the elephant man gets married.

A woman with an extremely rare skin disorder looks more than twice her age; a baby undergoes risky surgery to cure a mysterious brain condition; three brothers with the same genetic disorder hope for a miracle.

Doctors operate on a huge neck tumor; an English teen is diagnosed with a rare aging condition; an Indian baby is born with an extra head.

Doctors operate on a huge neck tumor; an English teen is diagnosed with a rare aging condition; an Indian baby is born with an extra head.

A look at a wibbly wobbly man, a Frenchman with a rare shaking condition and an American woman with an enormous stomach tumor.

A teenager is rushed to the hospital after taking aspirin to help alleviate altitude sickness; a woman has pain in her arm that mysteriously spreads.

A 3-month-old boy has breathing difficulties; a woman has stomach problems; stepping on a crochet hook causes strange problems for a patient.

Twins battle seemingly unrelated illnesses.

A woman experiences perpetual stomach pain; another faces extreme fatigue and night sweating while pregnant.

A pregnant woman experiences stomach pains and headaches; another woman experiences eye inflammation and joint stiffness.

An aspiring actress awakens to an excruciating pain on the right side of her face; Bill experiences nausea and strange tingling in his legs; doctor visits and MRI tests show how these two different cases reveal paralysis.

Twins battle seemingly unrelated illnesses.

A woman experiences perpetual stomach pain; another faces extreme fatigue and night sweating while pregnant.

A pregnant woman experiences stomach pains and headaches; another woman experiences eye inflammation and joint stiffness.

An aspiring actress awakens to an excruciating pain on the right side of her face; Bill experiences nausea and strange tingling in his legs; doctor visits and MRI tests show how these two different cases reveal paralysis.

A teenager is rushed to the hospital after taking aspirin to help alleviate altitude sickness; a woman has pain in her arm that mysteriously spreads.

A 3-month-old boy has breathing difficulties; a woman has stomach problems; stepping on a crochet hook causes strange problems for a patient.

A woman has shortness of breath, chest and joint pain, extreme fatigue and cough; strange symptoms appear in an energetic kindergartener.

A college student is misdiagnosed with pneumonia.

A baby girl turns blue 30 minutes after her birth.

A new baby is plagued with health problems.

A woman who successfully gives birth after two miscarriages faces challenges.

A baby develops a bulging forehead and eye color changes; a teen suffers hand pain during swim practice.

A woman experiences dizzy spells after a vacation; a woman suffers stomach pain and bizarre swelling.

One man hasn't seen his mom since he was six, when she walked into a grocery store and never came out; a 54-year-old hopes to meet her biological family.

Photo evidence suggests that an adoptee and mother may have been unknowingly connected for years; a woman discovers some shocking news about her biological family.

Two sisters confront their Puerto Rican birth father after a lifetime of feeling abandoned; an adoptee turns her back on an upsetting past, as the new relationship with her biological mother flourishes.

Newly reunited sisters face a battle that strengthens their bond and uncover another secret held by their mother; two families explore the complicated relationship of sharing a son.

After hearing a shocking story from her biological mother, Kris seeks more answers about the disturbing truth behind her birth father; two strangers come forward with a potential connection to her story.

After Thomas Hicks sold over 200 babies illegally in the 1950s and 1960s, Jane Blasio works to reunite the stolen babies with biological families while trying to unearth secrets about Hicks himself.

Jane discovers a suspicious pattern of babies with extremely low birth weights coming out of the clinic; Chris finds out that Dr. Hicks may have hidden birth records in his mausoleum; Diane hopes to meet her biological father.

Jane and Lisa meet the first Hicks baby, Stephen Dilbeck; Chris and Sallie open the mausoleum in search of birth records rumored to be inside as they work on getting approval of an exhumation.

Stephen Dilbeck gets some shocking information about his birth family from Jane and Lisa; Chris and Sallie work on getting approval of an exhumation that will answer questions for hundreds of Hicks babies.

Jane and Lisa share the news about the exhumation with a group of Hicks babies that have questioned whether Dr. Hicks was in fact their biological father; Sallie and the Hicks babies learn the DNA results.

Wendy and her team encounter unexpected challenges with the exhumation; Sallie struggles emotionally with her decision to exhume; the Hicks babies learn the DNA results; three Hicks babies are connected with biological family.

Jane and Lisa meet the first Hicks baby, Stephen Dilbeck; Chris and Sallie open the mausoleum in search of birth records rumored to be inside as they work on getting approval of an exhumation.

Stephen Dilbeck gets some shocking information about his birth family from Jane and Lisa; Chris and Sallie work on getting approval of an exhumation that will answer questions for hundreds of Hicks babies.

Jane and Lisa share the news about the exhumation with a group of Hicks babies that have questioned whether Dr. Hicks was in fact their biological father; Sallie and the Hicks babies learn the DNA results.

Wendy and her team encounter unexpected challenges with the exhumation; Sallie struggles emotionally with her decision to exhume; the Hicks babies learn the DNA results; three Hicks babies are connected with biological family.

After Thomas Hicks sold over 200 babies illegally in the 1950s and 1960s, Jane Blasio works to reunite the stolen babies with biological families while trying to unearth secrets about Hicks himself.

Jane discovers a suspicious pattern of babies with extremely low birth weights coming out of the clinic; Chris finds out that Dr. Hicks may have hidden birth records in his mausoleum; Diane hopes to meet her biological father.

Fearing he'll suffer the same fate as 700-pound brother David, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.

At over 700 pounds, Teretha's life is confined to a bed, which is a long way from her former job representing Detroit's healthy eating program; a gastric bypass will hopefully save her life.

Milla is bedridden and dependent on her husband and five kids, who can't resist her unending requests for junk food.

Former plus-size model and advocate Renee realizes the mortal mistakes she has made as her weight swells to 600 pounds and her health crumbles.

Jennifer and her daughter Marissa are stuck in a co-dependent relationship and, with a combined weight of over 900-lbs., both of their lives are in jeopardy; Jennifer must regain control and save both of their lives before it is too late.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

After a difficult childhood with an abusive stepfather and drug-addicted mother, Sarah is fighting for her life at only 24 years old.

With the support of his fiancé, Kathryn, Robert turns to Dr. Nowzaradan in a final, desperate attempt to save his life; he tries to reverse a lifelong food addiction that has left him bed-bound, saddled with grotesque lymphedema, and nearly 900-lbs.

A year since her weight-loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat her if she can't find a way to control her eating habit and start walking again.

Lee's anger issues continue to jeopardize his relationship with Rena and threaten to derail both of their weight-loss journeys; a major life event sends Sarah into a depression that she must pull herself out of if she wants to keep losing weight.

A year since her weight-loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat her if she can't find a way to control her eating habit and start walking again.

Lee's anger issues continue to jeopardize his relationship with Rena and threaten to derail both of their weight-loss journeys; a major life event sends Sarah into a depression that she must pull herself out of if she wants to keep losing weight.

With the support of his fiancé, Kathryn, Robert turns to Dr. Nowzaradan in a final, desperate attempt to save his life; he tries to reverse a lifelong food addiction that has left him bed-bound, saddled with grotesque lymphedema, and nearly 900-lbs.

Diane has tumors all over her body that have ruined her life; Will fears his shoulder lump will be ripped open at work; Anthony's daughters force him to get his lump examined; a woman detests her hideous varicose veins.

Taylor has a large bump at the base of her spine that is far more dangerous than she realizes; John jokes about his hip lump, but it's no laughing matter; Noelle had her ears stretched as a teen, but now wants them repaired.

Louis is a veteran who is covered in scaly, dry skin that makes him feel like an alligator; Irais's kids are bullied because of the embarrassing growth on her head; Johnny has been living with a stubborn lump on his back for too long.

Patrick's nose is covered by huge bumps, and he can barely breathe; Aziza and Lauren are friends who bonded over their matching wrist lumps; Joe has a mound in the middle of his forehead that looks like a third eye.

April is covered in bumps that have disfigured her arms; Genner has flown all the way from the Philippines to have Dr. Lee help with his bumpy nose; Chris suffers from psoriasis that nearly covers his body and a bump on his head.

Matt has a skin condition that causes tumors to grow all over his body; Yamileth hasn't pursued her dreams because of the lump on her neck; Pat is covered with dark spots from her neck to her abdomen; Jennifer has a unicorn bump on her forehead.

Amber has hundreds of tumors on her face; Antonio has a mound on his spine and is afraid it might be impossible to remove; sisters Cheri and Janice both suffer from possibly matching lumps; Tatiana has an embarrassing bump on her butt cheek.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Taylore is a beautiful young woman who has unsightly elf-like bumps on her ears; Jose never goes out because of the baseball-sized lump on his head; Ken is covered in painful bumps that make it difficult to do everyday things.

Josh has a large knot on his head resulting from a car crash from 18 years ago; Brittney is covered in mysterious bumps; TJ has a hard, curious lump protruding from his side; Luis has a bump on his shoulder and his daughters fear it's dangerous.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Leonard has an alarming bump hanging off of his arm that looks like it's breaking through the skin; Brandon has several lumps on his head that make him fearful for his life; Jess gets a noticeable lump on her butt after falling down the stairs.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Tony has large growths on his nose that impair his breathing; Kevin has a bump in his jawline that is a lady deterrent; Marie has an unsightly lump on her forehead that makes her a hermit; Tommy's leg bump makes it difficult for him to work.

Gerard has nearly a hundred lumps varying in size all over his body; Gina has bloody lesions all over; Eric has a large bump on his head that he calls his on and off button.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Tony has large growths on his nose that impair his breathing; Kevin has a bump in his jawline that is a lady deterrent; Marie has an unsightly lump on her forehead that makes her a hermit; Tommy's leg bump makes it difficult for him to work.

Gerard has nearly a hundred lumps varying in size all over his body; Gina has bloody lesions all over; Eric has a large bump on his head that he calls his on and off button.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

A woman gives birth prematurely during Hurricane Sandy; an Army soldier coaches his wife's delivery from Afghanistan; a baby delivered in a shopping mall parking lot.

A baby is born twice; a woman in labor is torn apart by a tornado; a wife gives birth at home.

A golfer's life-saving surgery; three nearly naked adults in the ER; a patient accidentally shot by his brother.

A elder playboy has a minor injury that turns deadly; a health fanatic's juice diet leaves him in a comatose state; while juggling multiple critical patients, doctors nearly misdiagnose one who has suddenly deteriorated.

A man injured by a boat propeller; a deadly chain of events; the ER comes to a standstill.

Two gunshot victims; a jogger goes into a coma; the ER staff becomes detectives.

A newlywed's hand gets stuck in a kitchen appliance; a student with an injury down under; a heavy drinker has complications.

A college student's face covered in a plaster mask; a stroke patient's heart keeps stopping and restarting without intervention.

Crystal has been eating household cleanser since she was twelve; Samantha tans up to three times a day.

Rebecca is addicted to shoes, calling them her babies; Haley has been pulling her hair out for over six years.

April can't go anywhere without her puppets; Debbie is allergic to cats, but has over twenty of them.

Cyntrelle spends eight hours every day obsessively scrubbing and cleaning her house, leaving her with no time for a job; Belinda can't stop collecting rocks and going on treks to find the perfect one.

Josh eats glass and bullets for attention; Candice believes bleaching her skin will make her more accepted.

Maureen wears make-up 24 hours a day, even while she's sleeping, despite the harmful effects on her skin; Barbara is fascinated with death and prefers the company of the dead to the living.

At fifteen, Kimberly started using laxatives to lose weight and is now addicted to them; Bianca craves pottery and ashes.

Cassie is so devastated by the sudden loss of her husband that she brings his urn with her wherever she goes, but she has taken her grieving to a new level.

A woman who drinks air freshener every day and a person obsessed with having the world's longest neck.

Kyle chooses to only date women over the age of 65; Adam is obsessed with transforming himself into Madonna.

A woman refuses to sleep without her blow dryer on the bed; a woman is addicted to eating toilet paper.

Davecat lives with his life-size doll and treats it as if it were his human wife, eating meals, shopping for her and more; Rachael spends hours a day picking scabs on her body.

A young couple is moving and decides to give the apartment a sexy goodbye, but that lands them in the ER; a woman pushes the limits with her trainer; a motorcycle escapade.

A couple's intimate game of cops and robbers; helping a patient out of a sticky situation while his in-laws watch; one man's excruciating post sex migraine.

A couple gets crazy in the kitchen; a patient arrives unconscious and oxygen-deprived; a couple's marathon love making session ends in emergency surgery.

A man becomes paralyzed after sex; a couple's birth plan leads to shocking symptoms; a man gives his girlfriend a special gift.

A young couple is moving and decides to give the apartment a sexy goodbye, but that lands them in the ER; a woman pushes the limits with her trainer; a motorcycle escapade.

A couple's intimate game of cops and robbers; helping a patient out of a sticky situation while his in-laws watch; one man's excruciating post sex migraine.

A couple gets crazy in the kitchen; a patient arrives unconscious and oxygen-deprived; a couple's marathon love making session ends in emergency surgery.

A man becomes paralyzed after sex; a couple's birth plan leads to shocking symptoms; a man gives his girlfriend a special gift.

A woman who drinks air freshener every day and a person obsessed with having the world's longest neck.

Kyle chooses to only date women over the age of 65; Adam is obsessed with transforming himself into Madonna.

A woman refuses to sleep without her blow dryer on the bed; a woman is addicted to eating toilet paper.

Davecat lives with his life-size doll and treats it as if it were his human wife, eating meals, shopping for her and more; Rachael spends hours a day picking scabs on her body.

Liz has gone from being bedbound with lymphedemas on both legs to standing and walking; if Jenn and Marissa can't get along as mother and daughter to lose weight, they'll have to proceed apart; with facts and bonus scenes.

Donald has difficulty walking and relies on his parents to take care of him, so he gets motivated to begin his weight loss journey.

Sean has a massive growth protruding from his side and skin so stretched it's tearing apart, forcing his mother to change both of their lifestyles before he can be approved for surgery.

In the fourth year of his weight-loss journey, Sean struggles to get past the loss of his mother and live on his own; Dr. Now intervenes to control Sean's eating for a time.

For Milla Clark, after three years and five surgeries, success would mean beating the odds and becoming one of Dr. Nowzaradan's most impressive weight-loss patients, but failure would mean slipping back to the bedbound life.

After a lifelong struggle with obesity, the three Perrio siblings travel to Houston in a last-chance journey to lose weight.

Tamy faces a tough choice when her husband wants her back, but only if she moves away from Houston and Dr. Now's program; Karina's weight loss begins to slow, but she finds happiness dating a guy Dr. Now is surprised to see in his clinic again.

Erica's success on her weight-loss journey is derailed by heartbreak; Benji must reach his goal weight without the support of his brother.

Alicia's relationship with her boyfriend, Tim, comes under the microscope; Pauline must beg her way back onto the program after quitting.

Dottie faces an unexpected challenge to her weight-loss when her husband's drinking problem becomes intolerable for her and her son; Cynthia starts to wonder if being there for her kids at her current weight is more important than losing more.

Alicia's relationship with her boyfriend, Tim, comes under the microscope; Pauline must beg her way back onto the program after quitting.

Dottie faces an unexpected challenge to her weight-loss when her husband's drinking problem becomes intolerable for her and her son; Cynthia starts to wonder if being there for her kids at her current weight is more important than losing more.

Erica's success on her weight-loss journey is derailed by heartbreak; Benji must reach his goal weight without the support of his brother.

In order to keep pace with her daughter Charly's impressive weight loss, Charity must do something she's never done and find a way to go it alone.

Henry hopes to transform himself for his high school reunion, and gastric bypass is the first step to combating his 715 pounds.

Ashley wants to achieve her goal of owning a childcare facility, but must lose weight before her dreams can be met.

Steven's dysfunction escalates, pushing his relationship with Dr. Nowzaradan; his brother Justin takes the leap to go to Houston to finally accept help.

At over 700 pounds, Brianne undertakes a weight-loss journey to save her own life; she faces an unexpected challenge to her fragile progress when her husband suffers a heart attack on a birthday she will never forget.

Octavia has been bedbound for nearly a year when she decides to make the trip to Houston to get help from Dr. Now, but when it turns out that her best friend is also her worst enabler, Octavia will have to choose between old habits and a new life.

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can't go; Chris' son Garrett, already 600 pounds at age 20, is game to join the journey.

A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food; only the help of Dr. Now's weight-loss program can restore his hopes of living a happy, productive life.

Holly already has one failed weight loss surgery, so to succeed this time, she must do more than change her eating habits, she must address the childhood issues that continue to plague her.

Lacey ballooned up over 600 lbs on pizza and ice cream and knows Dr. Now is her best hope for success; she must now rally her divorced parents around her for support and find a way to modulate her moods that won't include binge-eating.

Holly already has one failed weight loss surgery, so to succeed this time, she must do more than change her eating habits, she must address the childhood issues that continue to plague her.

Lacey ballooned up over 600 lbs on pizza and ice cream and knows Dr. Now is her best hope for success; she must now rally her divorced parents around her for support and find a way to modulate her moods that won't include binge-eating.

A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food; only the help of Dr. Now's weight-loss program can restore his hopes of living a happy, productive life.

Lindsey lost 140 pounds, but her sagging skin keeps her athletic dreams out of reach; Derek wants to pass the Police Academy physical but his excess skin prevents him from training.

Brian once weighed over 600 pounds and now has lots of sagging skin; Tanya lost nearly 200 pounds and her excess skin drapes over her new frame.

Ariel is 23 and has already lost 260 pounds, but finds the excess skin less feminine than being obese; spirited Chantae is desperate to enjoy life again after losing 222 pounds.

Three inspirational young women have a number of conditions that cause the lower limbs to grow or swell excessively.

Four moms-to-be who are morbidly obese; these women challenge the perception and the odds on their journey to motherhood.

An obese woman is accused of murder after being charged with crushing her nephew to death.

Since her acquittal of her nephew's murder, a woman has taken steps to save her own life in hopes to adopt her nieces and nephew; the challenges of losing a large amount of weight.

A woman undergoes a face transplant; a Chinese boy has a very long neck; a girl has a huge amount of excess hair; a boy has a giant scrotum.

A look at the lives of four pairs of conjoined twins; they manage to lead remarkably normal lives despite their conditions.

Featuring an eight foot tall teen, a boy from India who possesses his own tail, a man with super sized muscles and a lobster woman.

A teenager in desperate need of surgery to remove a face tumor, a woman whose body is turning to stone, and a man that has found the perfect use for his enormous arm.

A teen who has aged prematurely; a school teacher who cries crystals; a mother with very brittle bones; a boy with butterfly skin.

An infant screams in the pool; a mother is struck by a series of headaches.

Parents notice their 7-month-old son has troubling physical impairments; a woman traveling the world starts experiencing unusual back pain and tingling in her feet.

A newborn looks handicapped; a newlywed wakes to debilitating nausea.

A 3-year-old's motor skills begin to deteriorate; a woman experiences fatigue after the birth of her second child.

A teen inexplicably suffers kidney failure; doctors cannot diagnose the slow growth of a fetus.

An infant's hip hurts mysteriously.

A newborn looks handicapped; a newlywed wakes to debilitating nausea.

A 3-year-old's motor skills begin to deteriorate; a woman experiences fatigue after the birth of her second child.

A teen inexplicably suffers kidney failure; doctors cannot diagnose the slow growth of a fetus.

An infant's hip hurts mysteriously.

An infant screams in the pool; a mother is struck by a series of headaches.

Parents notice their 7-month-old son has troubling physical impairments; a woman traveling the world starts experiencing unusual back pain and tingling in her feet.

Charity's sixth child is on the way; Natasha fears her boyfriend will leave her.

Bethany is pregnant by her unemployed boyfriend; Cecily fears her pregnancy.

Ashley struggles with three children, one with cerebral palsy and a stepson, and she is afraid to reveal that she is pregnant; Amatulla is embarrassed to be pregnant again.

Kelly's history of miscarriages; Lauren fears her father.

Katy has been a meth addict for ten years and is pregnant.

A woman who entered prison three months pregnant will raise her baby in prison through the duration of her sentence.

Jenna's life is dominated by fear of contamination OCD; with a second child on the way, Jenna struggles with her condition that worsens with pregnancy; she dictates both her marriage and young son's life.

Jolene and her boyfriend Correy are expecting a baby girl; Jolene has to choose between taking the psychiatric drugs that control her bi-polar disorder and safeguarding the health of her unborn child.

An HIV-positive woman is expecting her second child.

Shanice is pregnant with her second child; she is morbidly obese with a BMI of over 50 percent; Shanice knows she must change her lifestyle and eating habits.

While attempting to recover from the stress of getting mugged and a bad fall, Nikki finds out she is pregnant and full term.

Paramedics rush Anna to a hospital on Christmas Eve for what she thinks is food poisoning only to discover she's 41 weeks pregnant, in labor and didn't know it.

Stabbing pains in the pelvis send a woman to an ER, where she discovers she has given birth, without realizing she was pregnant.

After spending a day with her family riding roller coasters at a theme park, a woman suddenly feels exhausted and nauseous, begins having cramps, heads to the bathroom, and gives birth to a baby boy on the floor.

A woman misses her period but a home pregnancy test is negative, so she thinks it must be the stress of her upcoming wedding until a few months later when she is shocked to find herself delivering a baby girl while on the toilet.

A woman with M.S. goes into labor without realizing she is pregnant.

A single mom struggling to make ends meet goes to an emergency room with what she believes is a burst appendix, but she's in for the shock of her life.

A woman believes her unborn child is actually indigestion.

A woman with a broken pelvis suddenly discovers she is pregnant, and both mother and child are in danger.

On the day before Halloween, Abbigale gives birth when she didn't know she was pregnant.

Phyllis and Patty aren't just identical twins, they are identical hoarders as well.

Lalie and her children suffer from mold, mice and flea infestations due to their upstairs neighbor and landlord, Denise, who is a massive hoarder.

Beverly's clutter has filled up her entire home and her three beloved dogs have helped make the space completely unlivable.

Terry and Bill seem to be the perfect couple; the murder of her daughter has led Nancy to hoard.

Jessica is a little person with dangerous toppling piles of clutter; along with her mother she has filled her entire home.

Frank didn't expect Susan to fill his house with clutter when she moved in; though her home of forty-eight years sits condemned just two blocks away.

Beverly's clutter has filled up her entire home and her three beloved dogs have helped make the space completely unlivable.

Terry and Bill seem to be the perfect couple; the murder of her daughter has led Nancy to hoard.

Jessica is a little person with dangerous toppling piles of clutter; along with her mother she has filled her entire home.

Frank didn't expect Susan to fill his house with clutter when she moved in; though her home of forty-eight years sits condemned just two blocks away.

Phyllis and Patty aren't just identical twins, they are identical hoarders as well.

Lalie and her children suffer from mold, mice and flea infestations due to their upstairs neighbor and landlord, Denise, who is a massive hoarder.

Brandon is a talented musician with a beautiful voice and a run-away weight problem; he wants to lose weight and embark on a career; he also wants to take the next step with his girlfriend, Taylor, whom he risks losing if he can't make a change.

Zsaylnn needs to lose weight to be the mother her daughter deserves; her husband loves large women and does not support her goals.

A woman battles severe depression and has not left her Chicago basement in two years; the hope of having a life-changing surgery.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Despite moving to Houston with the solid support of her boyfriend, Aaron, and her cousin, Jasmine, Tiffany finds it difficult to break the cycle of depressed eating when her two roommates don't join her diet and leave the house every day for work.

Born as "Matthew," Destinee never felt like she fit in; now, having come out as a 600-pound transgender woman, she likes her curves, but she will need to say goodbye to them if she wants to be approved to transition completely.

Jeanne lives in an unhygienic household with her mother and schizophrenic father; at well over 600 pounds, Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father for help instead. Aaron must learn to care for himself to avoid eating himself to death.