One year after Maine resident Pearl A. Bruns' disappearance, forensic technology helps to find her body and determine who was responsible for her death.

When 4-year-old April Renee Tucker is found dead in her backyard, her parents tell the police that neighborhood dogs attacked and killed her, but the injuries on her body don't match their account of what happened.

San Diego police investigate the murder of a missing person whose hands turn up in a dumpster; an anonymous letter, containing details only the killer would know, offers clues to solving the case.

One year after her father's death, a teen's role in a high school production of "Hamlet" causes her to reveal the chilling truth behind her family's tragedy.

A mother puts her hope in the internet and an independent investigation to clear her name after authorities charge her with murdering her 17-month-old son in a fire considered to be intentionally set.

A forensic scientist uses his skills to preserve a footprint left in snow to help authorities nab two men suspected of robbing an Ontario couple and shooting the husband in the head.

Fingerprints taken from a piece of cloth help solve the rape and murder of a 22-year-old woman in Henrico County, Va.

The FBI profiles a suspect in the kidnapping and murder of a 6-year-old girl during an evening church service; a witness leads authorities to the likely killer, but then becomes a victim herself.

Photographs found in a dumpster lead to the killer of Los Angeles model Linda Sobek; the man claims he did not intentionally kill her despite evidence to the contrary.

A murder mystery theater performance in Easton, Md., turns into a real-life mystery when a body is found after the performance ends.

When a woman dies in a horseback riding accident, police uncover a web of lies in her husband's background after his suspicious behavior prompts a closer look.

A serial killer in Tampa, Fla., taunts police by strangling prostitutes and leaving their bodies in plain sight, but tire marks and fibers lead to the culprit.

Missouri police are thrust into a bizarre web of homeless drifters and cattle auctions when they are called to retrieve a dead body.

A killer wants to outwit the police and keep the identity of his victim secret so he removes the teeth; however, lab tests on the skull reveal not just the horrific nature of the murder, but the identity of the victim too.

When a 23-year-old Marine dies in his bedroom, doctors initially believe a heart attack is to blame; when arsenic is found in his organs, his wife is charged with murder; a sharp attorney and toxicological testing uncover the truth.

When an 18-year-old girl is abducted while talking on a pay phone, forensic evidence found on her clothing points police in the direction of a suspect who shockingly confesses that he didn't act alone.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Todd Kohlhepp's double life is exposed after police rescue a young woman chained like a dog inside a shipping container on his property.

A registered sex offender lures Cherish Perrywinkle, 8, away from a Walmart, and that's just the beginning of a night of terror, all caught on camera.

Fitness instructor Missy Bevers is stabbed and bludgeoned to death while setting up for an early-morning workout class at the local church; surveillance cameras capture a series of images of her killer lurking in the hallways.

Model Tara Lambert hires a hit man to kill her husband's ex-wife and put her in a wood chipper, but she doesn't know that cameras are rolling.

When a fundamentalist group is accused of robbing banks, authorities know they are dealing with experienced criminals and overwhelming evidence, but the defense is very well-funded.

When a young doctor is accused of sedating and sexually assaulting two of his female patients, DNA tests show him to be innocent, but the women persist with their claims; seven years later, a private investigation leads to a surprising discovery.

The search for the killer of two teenagers in Texas shows a behavioral study on how most serial killers also have a history of abusing animals.

When a farmer's wife disappears, the tests of a plant pathologist and a dendrochronologist lead to a surprising revelation.

A son who is convinced of his mother's innocence in the death of his father enrolls in law school to try and clear her name.

Despite a patient's claim that the cut to his hand had been caused by a dumpster, the doctor treating the injury recognizes it as something else - and soon becomes the chief witness in a murder case.

The pornography empire cultivated by brothers Artie and Jim Mitchell crumbles when one turns up dead and his brother confesses to shooting him; investigators question whether the shooting was premeditated.

When prison guard Donna Payant's body is discovered at a landfill, a medical examiner uses a "signature" clue to link her death to a murder the same examiner investigated 10 years earlier.

When a 9-year-old girl vanishes on her way to school, the entire community helps with the search; detectives believe her mother may be involved, and a hidden fingerprint seals the case.

The investigation of a murder case in New Jersey is stalled until a similar attack occurs on a state trooper in Maine.

A young woman goes missing without leaving many clues, but the advanced technology on offer makes it possible for cat hairs and insects to help build an image of the abductor.

Blood spatter analysis and an investigation lead police to the truth when a pregnant woman is found dead in her home.

A mother is determined to discover what happened when her daughter is injured in a hit-and-run accident.

Forensic science and deductive reasoning determine what happened to a mother and daughter while they were on a shopping spree.

Exploring how an American hit single from 1966 - "The Cheater" by Bob Kuban and the In-Men - foreshadowed the demise of the group's lead singer, Walter Scott.

Eight years after a man confessed to the murder of a young woman, another man claims that he committed the crime, and investigators must use forensic evidence to determine the true killer.

Although a group of teenage thugs are suspected of attacking two boys on a fishing trip, there is no solid evidence until a murky fishing hole provides some answers.

When young prostitute's body turns up in an Ohio waterway, authorities have one tiny clue which could point to her killer, but face huge challenges due to her policemen clients and DNA evidence being washed away.

A son who is convinced of his mother's innocence in the death of his father enrolls in law school to try and clear her name.

Despite a patient's claim that the cut to his hand had been caused by a dumpster, the doctor treating the injury recognizes it as something else - and soon becomes the chief witness in a murder case.

The pornography empire cultivated by brothers Artie and Jim Mitchell crumbles when one turns up dead and his brother confesses to shooting him; investigators question whether the shooting was premeditated.

When prison guard Donna Payant's body is discovered at a landfill, a medical examiner uses a "signature" clue to link her death to a murder the same examiner investigated 10 years earlier.

When a 9-year-old girl vanishes on her way to school, the entire community helps with the search; detectives believe her mother may be involved, and a hidden fingerprint seals the case.

The investigation of a murder case in New Jersey is stalled until a similar attack occurs on a state trooper in Maine.

A young woman goes missing without leaving many clues, but the advanced technology on offer makes it possible for cat hairs and insects to help build an image of the abductor.

Blood spatter analysis and an investigation lead police to the truth when a pregnant woman is found dead in her home.

A mother is determined to discover what happened when her daughter is injured in a hit-and-run accident.

Forensic science and deductive reasoning determine what happened to a mother and daughter while they were on a shopping spree.

Exploring how an American hit single from 1966 - "The Cheater" by Bob Kuban and the In-Men - foreshadowed the demise of the group's lead singer, Walter Scott.

Eight years after a man confessed to the murder of a young woman, another man claims that he committed the crime, and investigators must use forensic evidence to determine the true killer.

Although a group of teenage thugs are suspected of attacking two boys on a fishing trip, there is no solid evidence until a murky fishing hole provides some answers.

When young prostitute's body turns up in an Ohio waterway, authorities have one tiny clue which could point to her killer, but face huge challenges due to her policemen clients and DNA evidence being washed away.

In the story of a Los Angeles kidnapping, ransom and murder ring, retired scientists use sonar equipment to locate victims at the bottom of a reservoir.

Patients at the VA Hospital in Clarksburg, W.Va., keep dying after experiencing shockingly low blood sugar levels; an investigation into their deaths reveals an overnight nurse was injecting patients with lethal doses of insulin.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

During a terrifying three-day period in late August 1990, five college students were found brutally murdered in Gainesville, Fla.; panic filled the usually sunny city as investigators searched to find the serial killer before he struck again.

Five college students were found brutally murdered in Gainesville, Fla. but it would take investigators months, and the discovery of a campsite, a screwdriver and an audio tape, before they identified who the serial killer was.

Elizabeth Smart was kidnapped from her Salt Lake city home in 2002 and snatched from her bed at knifepoint by a mysterious man in the middle of the night; to the public it seemed as if she had vanished into thin air.

For nine months in 2002, 14-year-old Elizabeth Smart was the most famous missing child in America; kidnapped by Brian David Mitchell, she was forced up into a hiding spot in the mountains behind her home, assaulted and forced to be his second wife.

In a small South Carolina town in 1991, 17-year-old Crystal Faye Todd, a popular high school student, is raped, murdered and dumped in a deserted field; with few leads, authorities test the DNA of several friends, and one match shocks everyone.

In a groundbreaking case using animal DNA, investigators use forensic testing on a cat to help them solve the case of a woman who vanished from her home on Prince Edward Island.

A look into the 1984 Oregon food poisonings, where detectives track down the outbreak to a cult which aims to use germ warfare to take down the government.

A woman is found dead from a gunshot wound and police suspect her husband, however, forensic teams prove what really happened and the truth is stranger than fiction.

After American Atheists founder Madalyn Murray O'Hair disappears, the discovery of a mutilated body helps police catch the culprit.

Two people witness a truck driving over an unconscious man and flee into a nearby bar, but when the police turn up, the truck, the man and the witnesses are gone.

Insect evidence helps to solve the mystery of a woman found dead near a river bank.

A girl who is abducted and then released soon afterwards uses her knowledge of forensics to lead police to the kidnapper.

A trash collector finds a severed human leg in a trash bin but police cannot use conventional methods of victim identification; investigators turn to toxicology and DNA tests to find the murder-mutilator.

A coroner finds telltale clues on the badly burned body of a murder victim, sending police in pursuit of a couple of killers.

A man is arrested and convicted for a series of sexual assaults in Indiana; years later, forensic developments reveal new facts about the case.

The murder of a young Seattle couple puzzles investigators until the victims' dog, Chief, leads police to the killer.

A handsome young doctor's fiancee experiences severe illness after revealing that she is pregnant, and launches her own investigation to determine if the doctor is somehow responsible.

A seemingly model citizen turns out to be a serial killer.

An abandoned, still-running car leads investigators to a body with unusual marks and a DNA trail that lead to the killer.

Police find fragments of deleted computer files leading them to suspect a woman's suicide is really murder.

A suspicious neighbor gives police a break in a cold case.

A family suspects their teenage daughter's new friends were involved in her disappearance.

After American Atheists founder Madalyn Murray O'Hair disappears, the discovery of a mutilated body helps police catch the culprit.

Two people witness a truck driving over an unconscious man and flee into a nearby bar, but when the police turn up, the truck, the man and the witnesses are gone.

Insect evidence helps to solve the mystery of a woman found dead near a river bank.

A girl who is abducted and then released soon afterwards uses her knowledge of forensics to lead police to the kidnapper.

A trash collector finds a severed human leg in a trash bin but police cannot use conventional methods of victim identification; investigators turn to toxicology and DNA tests to find the murder-mutilator.

A coroner finds telltale clues on the badly burned body of a murder victim, sending police in pursuit of a couple of killers.

A man is arrested and convicted for a series of sexual assaults in Indiana; years later, forensic developments reveal new facts about the case.

The murder of a young Seattle couple puzzles investigators until the victims' dog, Chief, leads police to the killer.

A handsome young doctor's fiancee experiences severe illness after revealing that she is pregnant, and launches her own investigation to determine if the doctor is somehow responsible.

A seemingly model citizen turns out to be a serial killer.

An abandoned, still-running car leads investigators to a body with unusual marks and a DNA trail that lead to the killer.

Police find fragments of deleted computer files leading them to suspect a woman's suicide is really murder.

A suspicious neighbor gives police a break in a cold case.

A family suspects their teenage daughter's new friends were involved in her disappearance.

A 70-year-old retired veteran is found dead on his boat after a bad sea storm; detectives discover he was killed during an attempted robbery after winning $400 in keno.

A Texas love triangle turns deadly, and it appears to be an open-and-shut case until technology tells the tale.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

After the discovery of the brutal murder of an 18-year-old desk clerk of a beachfront condo, analysts use brand-new mitochondrial DNA technology to prove the killer's identity.

A 33-year-old West Virginia husband and father seemingly dies in an accidental house fire; a closer look at the scene reveals a more sinister case.

July Fourth weekend leads to tragedy for a California family; to catch a killer, detectives utilize an unorthodox technique - analyzing bug fragments - to help put a murderer behind bars.

A family mourns the unexpected death of a beloved grandmother at Christmas, and while local police assure everyone that she was the victim of a tragic accident and that there is no foul play, some things about the scene don't add up.

When a true crime hobbyist connects a Utah Jane Doe to an Ohio missing persons case, detectives are hard-pressed to solve the decades-old murder.

A young Colorado mother suddenly vanishes on Thanksgiving, but when police trace her cell phone, it leads them to a surprising character with an even more surprising story.

Eight days after she disappeared on her way to a family ski trip, an 18-year-old woman's partially nude body is found floating in a river in Wyoming; years later, DNA technology uncovers dark secrets that led to her demise.

An upscale apparel store in Bethesda, Md., is the site of a gruesome scene when an employee is killed and her co-worker is battered and tied up, but surveillance video and blood evidence shed further light on the crime.

When a 62-year-old man opens a car restoration business and becomes seriously ill, his doctors cannot find the cause, but forensics can; identification of a highly toxic metal in the victim's blood leads to his poisoner.

When a 6-year-old disappears, her father becomes the prime suspect; he fails a polygraph test and even confesses, but 10 years later, the investigation gets turned on its head.

Investigators build a makeshift tent around a woman's body and use super glue fumes to lift the killer's palm print from the victim's skin.

The disappearance of a mail-order bride proves suspicious when detectives learn that two of the Texas husband's previous wives had died in mysterious circumstances.

A jeweler's search through old sales records helps police find likely suspects in the murder of elderly couple Edward Kowalzck and Gertrude Thompson.

A garbage bag leads police to a child's killer.

An investigation into the disappearance of a young woman uncovers a tooth that helps police solve a crime without a body.

The sensitive nose of a forensic examiner sniffs out murder.

Discovering that an assault suspect is left-handed is crucial to a police investigation dating back 16 years.

Forensic scientists try to find a way to "lift" the serial number from a shotgun that's their only clue in a case.

Investigating the worst arson spree in U.S. history - a rash of more than 75 fires near Seattle.

Computers aid the police and FBI in solving a string of crimes.

Using an anonymous letter and geographical profiling, investigators close in on a serial rapist, and a cleverly obtained DNA sample confirms their suspicions.

When a young boy has serious respiratory problems and his father shows signs of early Alzheimer's disease, a chance encounter with a stranger kicks off an investigation into the cause.

Police in St. Petersburg, Fla., use cell phone mapping, wiretapping and a host of forensic evidence to find a surgeon's killer.

A woman wins her release after being imprisoned for allegedly killing her mother in a car fire.

Authorities are able to apprehend a kidnapper because he allowed his victim to write a will on a telltale pad of paper.

Experts debate whether an apparent heart attack victim died from natural causes or alleged poisoning by his girlfriend.

A jeweler's search through old sales records helps police find likely suspects in the murder of elderly couple Edward Kowalzck and Gertrude Thompson.

A garbage bag leads police to a child's killer.

An investigation into the disappearance of a young woman uncovers a tooth that helps police solve a crime without a body.

The sensitive nose of a forensic examiner sniffs out murder.

Discovering that an assault suspect is left-handed is crucial to a police investigation dating back 16 years.

Forensic scientists try to find a way to "lift" the serial number from a shotgun that's their only clue in a case.

Investigating the worst arson spree in U.S. history - a rash of more than 75 fires near Seattle.

Computers aid the police and FBI in solving a string of crimes.

Using an anonymous letter and geographical profiling, investigators close in on a serial rapist, and a cleverly obtained DNA sample confirms their suspicions.

When a young boy has serious respiratory problems and his father shows signs of early Alzheimer's disease, a chance encounter with a stranger kicks off an investigation into the cause.

Police in St. Petersburg, Fla., use cell phone mapping, wiretapping and a host of forensic evidence to find a surgeon's killer.

A woman wins her release after being imprisoned for allegedly killing her mother in a car fire.

Authorities are able to apprehend a kidnapper because he allowed his victim to write a will on a telltale pad of paper.

Experts debate whether an apparent heart attack victim died from natural causes or alleged poisoning by his girlfriend.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

The Zodiac Killer terrorizes Northern California in the late 1960s; he taunts the public with cryptic clues, threats of violence and ciphers that are supposed to lead to his identity, but mostly go nowhere.

The Zodiac Killer terrorizes Northern California in the late 1960s; he taunts the public with cryptic clues, threats of violence and ciphers that are supposed to lead to his identity, but mostly go nowhere.

More than 900 Americans died in an isolated jungle in northern Guyana in November 1978; Jim Jones has gone down in history as a madman who drove his followers to suicide, but the truth is more complicated and tragic than that.

More than 900 Americans died in an isolated jungle in northern Guyana in November 1978; Jim Jones has gone down in history as a madman who drove his followers to suicide, but the truth is more complicated and tragic than that.

From 1976 to 1977, David Berkowitz terrorizes New York City under his creepy self-given moniker: the "Son of Sam"; he is among the most infamous serial killers in American history.

In 1977, the city of New York is stalked by a seemingly faceless serial killer known as "Son of Sam"; after his final shooting takes him to Brooklyn, a twist of fate and a little luck leads to his capture.

When a 12-year-old was found dead in her home, police were left clueless until a string of burglaries months later. A trail of stolen goods may help solve a murder.

When 15 year-old Marlene Miller was murdered, it would take 24 years and several retrials before forensic scientists discovered the evidence to bring her killer to justice.

Detectives use a forged signature to find a woman's abductor.

A woman is killed two days before she was scheduled to testify against a man accused of assaulting her and the prime suspect has an alibi.

A bite mark is all the evidence needed to convict a suspect who was robbing tourists in Florida.

Technology able to analyze human bite-marks yields information on a woman's death.

A death in Pennsylvania is strikingly similar to one in North Carolina.

When a nurse starts experiencing a variety of flu-like symptoms, she discovers that she is HIV-positive; she learns that her infection was not accidental.

time of death becomes pivotal when a pregnant woman is found murdered in her air-conditioned bedroom.

An obscure print found at a crime scene.

A diner in a small town, an endocrinologist and a forensic botanist help destroy a prime suspect's alibi.

Neighbors do not hear the gunshots when a union official is killed in his home.

A man tells police he shot an intruder who murdered his wife; forensic evidence leads police to re-examine the man's motives.

A police officer claims his estranged wife's shooting death was a suicide, but investigators think it was a murder.

When fire fighters find a family dead inside their home, it appears to be a murder-suicide; clues at the scene lead investigators to believe otherwise.

A couple's murder leads investigators into the world of white supremacists and a string of hate crimes.

A rare gun and a victim's beloved dog help investigators trying to solve a multi-year long murder case where most of the witnesses were admitted drug users.

A search in Virginia's DNA databank reveals the identity of a news producer's murderer.

A bite mark is all the evidence needed to convict a suspect who was robbing tourists in Florida.

Technology able to analyze human bite-marks yields information on a woman's death.

A death in Pennsylvania is strikingly similar to one in North Carolina.

When a nurse starts experiencing a variety of flu-like symptoms, she discovers that she is HIV-positive; she learns that her infection was not accidental.

time of death becomes pivotal when a pregnant woman is found murdered in her air-conditioned bedroom.

An obscure print found at a crime scene.

A diner in a small town, an endocrinologist and a forensic botanist help destroy a prime suspect's alibi.

Neighbors do not hear the gunshots when a union official is killed in his home.

A man tells police he shot an intruder who murdered his wife; forensic evidence leads police to re-examine the man's motives.

A police officer claims his estranged wife's shooting death was a suicide, but investigators think it was a murder.

When fire fighters find a family dead inside their home, it appears to be a murder-suicide; clues at the scene lead investigators to believe otherwise.

A couple's murder leads investigators into the world of white supremacists and a string of hate crimes.

A rare gun and a victim's beloved dog help investigators trying to solve a multi-year long murder case where most of the witnesses were admitted drug users.

A search in Virginia's DNA databank reveals the identity of a news producer's murderer.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

Melanie Zanona; Catherine Lucey; Isaac Arnsdorf.

Newlywed Lauren Phelps is stabbed 123 times as she fights for her life; her killer may blame his deadly rampage on cold medicine.

After Florida mother Gretchen Anthony, 51, goes missing from her home, surveillance video tells a twisted tale of her final hours.

A romantic and scenic early morning boat ride turns deadly when Larry Isenberg falls overboard; investigators reveal the disappearance of half a million dollars, which could be motive for murder.

Twenty-four-year-old Alex Woodworth is brutally stabbed 16 times and left for dead hanging halfway out of the killer's car; as investigators peel back the layers, it's revealed the killer's many lovers is motive for murder.

Recently divorced mom-of-three Ingrid Lyne goes back into the dating scene and meets a man online, but her date at a baseball game will be her last; Seattle residents and investigators are shocked by a chilling crime scene.

A homicide detective claims his wife accidentally shot herself in the head, but the evidence indicates otherwise.

Officials probe the death of a woman investigating the possible side effects of the drug she was prescribed for bipolar disorder.

A chip of stainless steel brings a killer to justice 20 years after a woman's body is found in a ravine.

An 11-year-old girl is sexually assaulted and shot twice at close range.

A woman is killed weeks before testifying against the man who sexually assaulted her.

New York police hunt the Zodiac killer after a series of deadly attacks.

When a healthy young man dies mysteriously in his sleep, toxicology tests reveal that it may have been foul play. Could a `suicide note' hold the key to solving the case.

A child's memory, a diary and a forensic psychologist help investigators solve a young woman's murder.

Investigators weigh several theories while probing the death of a retired police officer, including a botched robbery and suicide.

The bodies of two young women are found in the ashes of an apartment fire.

Two different men report the murder of a single mother and when the case's other anomalies stall the police, a candy wrapper and seeds help expose the killer.

After a Connecticut man's body is found in a burning rental car on a Mexican highway, an insurance company suspects a scam.

When a pipe bomb rips through a rural home, killing a young man and seriously injuring his mother, detectives hope that the remnants of a mailing label will lead them to a killer.

A quiet residential community, shattered by the murder of a neighbor. See how modern techniques helped investigators catch the culprit in less than 12 hours.

A man is found dead in his Michigan auto-salvage shop.

A man is murdered in a drive-by shooting. When a mobile phone trace incriminates a killer, it's up to a forensic geologist to find evidence that he was at the scene.

When a teenage girl is found dead, her boyfriend confesses to her murder. However, in a strange twist, so does another man; police must determine which is the killer.

A high school gym teacher gives his friend a ride home but never returns; his wife and friend receive letters saying he started a new life, but they suspect foul play despite no body being discovered.

A woman is killed weeks before testifying against the man who sexually assaulted her.

New York police hunt the Zodiac killer after a series of deadly attacks.

When a healthy young man dies mysteriously in his sleep, toxicology tests reveal that it may have been foul play. Could a `suicide note' hold the key to solving the case.

A child's memory, a diary and a forensic psychologist help investigators solve a young woman's murder.

Investigators weigh several theories while probing the death of a retired police officer, including a botched robbery and suicide.

The bodies of two young women are found in the ashes of an apartment fire.

Two different men report the murder of a single mother and when the case's other anomalies stall the police, a candy wrapper and seeds help expose the killer.

After a Connecticut man's body is found in a burning rental car on a Mexican highway, an insurance company suspects a scam.

When a pipe bomb rips through a rural home, killing a young man and seriously injuring his mother, detectives hope that the remnants of a mailing label will lead them to a killer.

A quiet residential community, shattered by the murder of a neighbor. See how modern techniques helped investigators catch the culprit in less than 12 hours.

A man is found dead in his Michigan auto-salvage shop.

A man is murdered in a drive-by shooting. When a mobile phone trace incriminates a killer, it's up to a forensic geologist to find evidence that he was at the scene.

When a teenage girl is found dead, her boyfriend confesses to her murder. However, in a strange twist, so does another man; police must determine which is the killer.

A high school gym teacher gives his friend a ride home but never returns; his wife and friend receive letters saying he started a new life, but they suspect foul play despite no body being discovered.

When the 20-year-old clerk of an Atlanta-area smoke shop is gunned down during a robbery, investigators have only descriptions of the killers and the make of their getaway car; investigators use a videotaped confession to smoke out the killers.

California police are baffled when an innocent man's DNA is found at the scene of a deadly home invasion, and authorities team with the man's defense attorney.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

He calls himself "B.T.K." which stands for "Bind, Torture, Kill" and for decades this bloodthirsty serial killer terrifies Wichita as he murders again.

For years the BTK killer plays a cat and mouse game with law enforcement and the media taunting them as he seeks the attention he craves.

The summer of 1985 was one of the hottest Los Angeles had seen in a century. But terrified residents weren't sleeping with the windows open; a killer known as the "Night Stalker" was on the loose.

A tip from a teenage boy leads to the identity of the Night Stalker and twenty-four hours later a mob of angry citizens track him down and capture him.

A 16-year-old girl is killed in her own home by her mother and father. Her parents said they acted in self-defense, but the forensic evidence indicates otherwise.

Investigators determine if a computer crash which almost ruined a manufacturing company was accidental or deliberate sabotage.

Car with three Secret Service agents collides with local deputy's car; investigation launched into who was responsible for the deadly car accident finds two very different conclusions.

The derailment of the Sunset Limited was the deadliest train crash in U.S. history killing 47 passengers and crew with several more injured.

Arson investigators attempt to determine the cause of the 1987 fire at the Kings Cross Underground Station in London.

A discarded sleeping bag, containing bloody sneakers and a purse, leads police to the body of a young woman; a mark found on the victim's body enables police to track the killer.

A woman's apparent accidental death begins to look fishy after police uncover a letter written by the victim days before her untimely death.

An Alaskan trooper finds a woman's body beside a frozen road, but evidence is scant even after a suspected murder weapon is found.

Police link a clump of hair discovered in an isolated area with a woman who disappeared 20 years ago.

A news anchor is shot to death outside her home in an apparent crime of passion by a fan; a police dog tracks the scent of the killer back to the crime scene.

A fire, caused by an unattended cigarette, kills the estranged wife of a police officer; forensic scientists discover that the cause is far more complicated.

A trio of men, responsible for several bank robberies, leaves no evidence behind; forensic scientists help catch them by looking at the criminals' posture and clothing.

When a woman's bone marrow test reveals arsenic poisoning, investigators try to determine if it is due to groundwater contamination or something more sinister.

A missing bank president's body is found floating in a lake; the duct tape used in binding him to a chair helps solve the crime.

A husband was shot and killed, forensic psychiatry helped the wife to remember the details for what happened.

The body of a 16-year-old girl is discovered nine months after her disappearance; forensic scientists find clues that paint a virtual portrait of her killer.

A young woman falls to her death in what appears to be a tragic accident; a forensic exam of photos taken at the scene tells a different story.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

Arson investigators attempt to determine the cause of the 1987 fire at the Kings Cross Underground Station in London.

A discarded sleeping bag, containing bloody sneakers and a purse, leads police to the body of a young woman; a mark found on the victim's body enables police to track the killer.

A woman's apparent accidental death begins to look fishy after police uncover a letter written by the victim days before her untimely death.

An Alaskan trooper finds a woman's body beside a frozen road, but evidence is scant even after a suspected murder weapon is found.

Police link a clump of hair discovered in an isolated area with a woman who disappeared 20 years ago.

A news anchor is shot to death outside her home in an apparent crime of passion by a fan; a police dog tracks the scent of the killer back to the crime scene.

A fire, caused by an unattended cigarette, kills the estranged wife of a police officer; forensic scientists discover that the cause is far more complicated.

A trio of men, responsible for several bank robberies, leaves no evidence behind; forensic scientists help catch them by looking at the criminals' posture and clothing.

When a woman's bone marrow test reveals arsenic poisoning, investigators try to determine if it is due to groundwater contamination or something more sinister.

A missing bank president's body is found floating in a lake; the duct tape used in binding him to a chair helps solve the crime.

A husband was shot and killed, forensic psychiatry helped the wife to remember the details for what happened.

The body of a 16-year-old girl is discovered nine months after her disappearance; forensic scientists find clues that paint a virtual portrait of her killer.

A young woman falls to her death in what appears to be a tragic accident; a forensic exam of photos taken at the scene tells a different story.

Haunted by her mother's long-ago disappearance, a woman undertakes an investigation of her own and stumbles upon a dark family secret.

A young mother is found murdered in her home and there are two suspects with ample motive, but an unusual interview and security camera footage have investigators puzzled.

A fire leads investigators to reexamine an unusual death.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

On Oct. 25, 1994, Susan Smith reports that a carjacker has abducted her two young sons, Michael and Alexander; this report sets off a nationwide search for the boys; while the world waits for news about the boys, investigators deliver shocking news.

For nine days, the nation waits for news as to the whereabouts of missing 3-year-Michael and 14-month-old Alex Smith; then, there's a shocking break in the case; the boys' father, David, shares his heartbreaking story; a look at the investigation.

On Oct. 28, 2007, 23-year-old Stacy Peterson, the wife of veteran police sergeant Drew Peterson, goes missing. as police launch an intensive search to find Stacy, the case raises shocking new questions about her husband.

Actor-musician David Cassidy ("The Partridge Family") experiences the pressures of fame as a teen idol in the 1970s; in the end, his death is surrounded by mystery, leaving his family, friends and fans with more questions than answers.

The robbery and brutal murder of an elderly couple goes unsolved for 10 years; a forensic scientist makes history when he solves the crime.

A man is charged with the murder of a wrestling champion; six years later, a forensic animator testifies on his behalf.

A 19-year-old girl is found dead in her car in what appears to be a suicide; police discover that the victime was involved in a love quadrangle, giving several people motive to kill.

Fifteen years after a man disappears, using a metal detector, police find evidence which proves what had happened.

The body of a young California co-ed under an isolated interstate ramp sets off an investigation; San Diego police have no idea who would want her dead, but they discover a tiny, unique fiber on the victim's clothing.

Police become suspicious of a man who reported his wife missing 15 years after doing the same thing with his first wife.

While investigating the case of a Colorado hunter shot three times and killed, police suspect two murder weapons, and two killers, but forensic evidence points them closer to home.

A serial arsonist burns thousands of California homes and businesses.

A small community in upstate New York is devastated when a car accident claims the life of a well-respected nurse.

A woman disappears without a trace, and police learn two other women vanished under similar circumstances.

Hikers near Anchorage, Alaska discover a body wrapped in sheets edged in orange stitching; they discover threads of evidence clinging to the sheet.

The son of a murder victim contacts the police when a flight attendant is brutally murdered in a remarkably similar way.

A two-man shrimp boat sinks when a fast-moving, violent storm struck the Louisiana coast; a deckhand is considered a hero for trying to save the drowned captain, until his body is found.

A real estate tycoon must have had a premonition about foul play, as he wrote it in his will.

The cold-blooded murder of an American tourist in a Mexican resort causes law enforcement to focus on both sides of the border.

When a prominent banker's wife is kidnapped, the trail leads police on a wild goose chase; they track down disgruntled bank customers and examine computer fonts.

A man has no recollection of events after stabbing his wife and holding her head underwater in a swimming pool.

A fire investigator determines if a kerosene heater is the cause of a fire that killed one person or if it was murder.

The body of a young California co-ed under an isolated interstate ramp sets off an investigation; San Diego police have no idea who would want her dead, but they discover a tiny, unique fiber on the victim's clothing.

Police become suspicious of a man who reported his wife missing 15 years after doing the same thing with his first wife.

While investigating the case of a Colorado hunter shot three times and killed, police suspect two murder weapons, and two killers, but forensic evidence points them closer to home.

A serial arsonist burns thousands of California homes and businesses.

A small community in upstate New York is devastated when a car accident claims the life of a well-respected nurse.

A woman disappears without a trace, and police learn two other women vanished under similar circumstances.

Hikers near Anchorage, Alaska discover a body wrapped in sheets edged in orange stitching; they discover threads of evidence clinging to the sheet.

The son of a murder victim contacts the police when a flight attendant is brutally murdered in a remarkably similar way.

A two-man shrimp boat sinks when a fast-moving, violent storm struck the Louisiana coast; a deckhand is considered a hero for trying to save the drowned captain, until his body is found.

A real estate tycoon must have had a premonition about foul play, as he wrote it in his will.

The cold-blooded murder of an American tourist in a Mexican resort causes law enforcement to focus on both sides of the border.

When a prominent banker's wife is kidnapped, the trail leads police on a wild goose chase; they track down disgruntled bank customers and examine computer fonts.

A man has no recollection of events after stabbing his wife and holding her head underwater in a swimming pool.

A fire investigator determines if a kerosene heater is the cause of a fire that killed one person or if it was murder.

A young woman's naked body is discovered in a remote area leading forensic investigators on a search for clues to her identity and the identity of her killer.

When a Yale student mysteriously vanishes days before her wedding, investigators comb a secure research lab for clues.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Chris Watts is convicted of murdering his wife and two daughters; secret videos document the chilling murders from start to finish, revealing lies, an affair and a cover-up.

Sasha Samsudean, 27, is found strangled to death in her luxury downtown Orlando, Fla., apartment; shocking surveillance video and a slew of clues ultimately lead investigators to the killer.

Beautiful college lacrosse player Yeardley Love is found murdered in her apartment, then the police arrest a member of a wealthy, prominent family, stunning the community.

Lululemon employee Jayna Murray is found stabbed to death inside one of the company's Washington, DC stores and her co-worker is found bound and bleeding in a room; different suspects emerge and evidence starts to point to someone on the inside.

California police in 1957 search for a murderer, but the case goes cold; 50 years after a crime is committed, advances in computer technology determine the killer.

Investigators piece together tiny clues at the scene of a hit-and-run accident; their findings help to track down the offending driver.

Investigators determine what caused a house fire that killed an elderly couple and whether the victims' son is responsible.

Detectives are suspicious after a woman is killed in a hunting accident, but it takes more than twenty years before a trace evidence analyst is able to match fibers on a soiled blanket to the killer.

When hunters find a skull in a Texas canyon, police find bits of clothing, a woman's shoe, some small bones and a strand of hair; once they discover her identity, it was time to find the killer.

A wife is missing in Key West; investigators wonder if they should be searching for a missing person or a killer.

Suicide notes and a pistol in hand lead police to suspect that a mother of two young children appeared to had killed herself, but when investigators learned of a house fire she was in three years earlier, they reinvestigate.

The violent death of an Air Force officer's wife outside a Philippines air base is examined, amid accusations of a love triangle involving the murdered woman's husband; investigators use groundbreaking computer forensics to make their case.

Pieces of plastic the size of sand hold clues to a bombing.

At first glance it appears a young woman suffocated, but further investigation shows the scene was staged.

A killer is careless when a home is destroyed by fire and a young boy is missing.

A patrol officer is shocked by the amount of blood at a traffic accident and is shocked by the coroner's ruling until an anonymous phone call re-ignites the case.

An irrigation canal murder remains unsolved until a similar murder occurs.

The light of day and DNA picture painted by molecular biologist reveals new clues about a nighttime traffic accident.

On Valentine's Day, an obstetrician finds his wife dead and calls 911; police discover inconsistencies between the blood spatter evidence and his version of events.

Weed analysis and photogrammetry are used to help solve the 1995 murder of a California teenager is found dead after disappearing from her home.

When police recover the submerged car of missing man, they find no body; the investigation that follows uncovers a deadly obsession and the motive for murder.

Emergency dispatch recieved a call from a man who said his girlfriend shot and killed herself. But the wound was not self-inflicted.

When hunters find a skull in a Texas canyon, police find bits of clothing, a woman's shoe, some small bones and a strand of hair; once they discover her identity, it was time to find the killer.

A wife is missing in Key West; investigators wonder if they should be searching for a missing person or a killer.

Suicide notes and a pistol in hand lead police to suspect that a mother of two young children appeared to had killed herself, but when investigators learned of a house fire she was in three years earlier, they reinvestigate.

The violent death of an Air Force officer's wife outside a Philippines air base is examined, amid accusations of a love triangle involving the murdered woman's husband; investigators use groundbreaking computer forensics to make their case.

Pieces of plastic the size of sand hold clues to a bombing.

At first glance it appears a young woman suffocated, but further investigation shows the scene was staged.

A killer is careless when a home is destroyed by fire and a young boy is missing.

A patrol officer is shocked by the amount of blood at a traffic accident and is shocked by the coroner's ruling until an anonymous phone call re-ignites the case.

An irrigation canal murder remains unsolved until a similar murder occurs.

The light of day and DNA picture painted by molecular biologist reveals new clues about a nighttime traffic accident.

On Valentine's Day, an obstetrician finds his wife dead and calls 911; police discover inconsistencies between the blood spatter evidence and his version of events.

Weed analysis and photogrammetry are used to help solve the 1995 murder of a California teenager is found dead after disappearing from her home.

When police recover the submerged car of missing man, they find no body; the investigation that follows uncovers a deadly obsession and the motive for murder.

Emergency dispatch recieved a call from a man who said his girlfriend shot and killed herself. But the wound was not self-inflicted.

A suitcase leads to the gruesome discovery of a nearly perfect crime.

A popular handyman in a New Hampshire town is found murdered and investigators follow forensic clues to a shocking conclusion.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

On April 19, 1995, Timothy McVeigh, a 26-year-old U.S. army veteran, detonated a 7,000 pound truck bomb outside the Alfred Murrah Federal Building in downtown Oklahoma City, claiming the lives of 168 innocent people.

Timothy McVeigh himself describes how events in his personal life inspired him to take action against his fellow Americans.

From 1979 to 1981, more than two dozen of Atlanta's black children disappeared without a trace; a look at who was killing the city's most vulnerable and why.

Investigators believe Wayne Williams, a 23-year-old black man murdered more than two dozen black children and young men in Atlanta; 40 year-old evidence is reexamined using modern forensics in search of more answers.

Investigators piece together evidence found at the scene of a Native American woman's murder; the tyre tracks and shoe impressions could lead them to the killer.

Experts seek answers to a young businesswoman's death just before she was to testify in a criminal trial.

An anonymous caller reports the rape and murder of a dry cleaner employee; two eyewitnesses tell two similar but not identical stories.

Police blame a botched robbery when an eccentric elderly millionaire is found dead, but the motive could be wrong.

Woman disappears from grocery store parking lot in Boulder, Colo.; investigators find extraordinary clues in a pair of bloody gloves, unique tire tracks, and ordinary grass and pine needles.

Retracing the steps of real investigations with interviews and dramatic re-creations as experts draw on forensic science to solve baffling crimes and other mysteries.

Police suspect a gay college student's slaying is a hate crime until forensic evidence points the case in another direction.

In a wealthy area of Philadelphia, police are called to the scene of what seems like a regular accidental drowning; the investigation begins to focus on one person who has many reasons to want the victim dead.

Two women are murdered in the same town and police fear a serial killer is on the loose, further investigation finds that they were both close to the same man.

A young woman is found dead on a golf course in the Bahamas; the grass on that course is so distinctive that it had evidentiary value; the evidence leds police to two suspects; each blamed the other, and they have to find out who the killer is.

A teenager goes missing after an evening of horseback riding; her body is found a month later, three miles from her home; the killer unknowingly leaves a trace of evidence behind, tiny but unmistakable clues that pointed to him and him alone.

When a popular disc jockey is found murdered in a community garden, police swing into action; a sniffer dog and a blood spatter expert led police to the killer and he'd been much closer than they realize.

Investigators unravel a twisted tale of lust, greed and deception after a woman claims her husband was gunned down by intruders.

Three seemingly unrelated deaths proved to be serial murders; the killer had been careful, he uses poison which had no taste or odour, fortunately for investigators, it also has a unique chemical signature.

A man is murdered in his sleep but no fingerprints are anywhere to be found; a shoe impression outside could lead to the killer.

With very little else to go on, investigators find that a show impression puts them on the right track to finding a killer in Lansing, Mich.

The owner of a restaurant is killed; investigators uncover tales of debt and deceit, but the case remains open, until one detective gets inspired by an earlier episode of "Forensic Files," and looks for clues in an empty holster.

A serial arsonist was on the loose in Washington, DC. Each of the fires was started with the same type of incendiary device. The perpetrator was very careful, and seemed to leave no evidence behind... but there were clues in the ashes and it was up to forensic scientists to find them.

Woman disappears from grocery store parking lot in Boulder, Colo.; investigators find extraordinary clues in a pair of bloody gloves, unique tire tracks, and ordinary grass and pine needles.

Retracing the steps of real investigations with interviews and dramatic re-creations as experts draw on forensic science to solve baffling crimes and other mysteries.

Police suspect a gay college student's slaying is a hate crime until forensic evidence points the case in another direction.

In a wealthy area of Philadelphia, police are called to the scene of what seems like a regular accidental drowning; the investigation begins to focus on one person who has many reasons to want the victim dead.

Two women are murdered in the same town and police fear a serial killer is on the loose, further investigation finds that they were both close to the same man.

A young woman is found dead on a golf course in the Bahamas; the grass on that course is so distinctive that it had evidentiary value; the evidence leds police to two suspects; each blamed the other, and they have to find out who the killer is.

A teenager goes missing after an evening of horseback riding; her body is found a month later, three miles from her home; the killer unknowingly leaves a trace of evidence behind, tiny but unmistakable clues that pointed to him and him alone.

When a popular disc jockey is found murdered in a community garden, police swing into action; a sniffer dog and a blood spatter expert led police to the killer and he'd been much closer than they realize.

Investigators unravel a twisted tale of lust, greed and deception after a woman claims her husband was gunned down by intruders.

Three seemingly unrelated deaths proved to be serial murders; the killer had been careful, he uses poison which had no taste or odour, fortunately for investigators, it also has a unique chemical signature.

A man is murdered in his sleep but no fingerprints are anywhere to be found; a shoe impression outside could lead to the killer.

With very little else to go on, investigators find that a show impression puts them on the right track to finding a killer in Lansing, Mich.

The owner of a restaurant is killed; investigators uncover tales of debt and deceit, but the case remains open, until one detective gets inspired by an earlier episode of "Forensic Files," and looks for clues in an empty holster.

A serial arsonist was on the loose in Washington, DC. Each of the fires was started with the same type of incendiary device. The perpetrator was very careful, and seemed to leave no evidence behind... but there were clues in the ashes and it was up to forensic scientists to find them.

A young mother is murdered in a crowded parking lot in broad daylight.

A serial killer terrorizes a small Texas town.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

A mysterious murder in an upscale community is solved by cell phone forensics.

After the brutal slaying of a young couple on a road trip, the victims' families begin receiving disturbing letters.

After a young mother is found brutally murdered in her home, investigators find startling clues on her cell phone that could lead to her killer.

An amazing new forensic tool turns a cold case around.

A gruesome find in a small town church sends investigators searching for a killer.

An insurance agent is shot execution style in his office, but the killer leaves no fingerprints, and there are no murder weapon found at the scene; then investigators discover a critical clue invisible to the naked eye that cracks the case.

A healthy, young mother mysteriously dies after a minor traffic accident triggering an investigation.

Investigators search for clues after a body is discovered in a watery grave.

A man becomes the prime suspect in his wife's death after forensic science raises questions about her apparent suicide.

Investigators on both sides of the Atlantic seek links between three homicides that look like professional executions.

Who put a bomb in the home of a 29-year-old woman and killed her?

A killer tried to destroy everything which could link them to the crime; but in doing so, they inadvertently created new forensic evidence, evidence which came to light using a technique never before used in a criminal investigation.

After a tycoon's wife is found dead in her SUV submerged in a half-frozen creek, police begin to suspect it wasn't an accident.

A Russian immigrant is found dead and a strange phone call to his office is the only lead investigators have.

Physical evidence intially condemns a prime suspect to a double homicide, but DNA from a discarded spoon points to another.

A child's death from flu-like symptoms triggers an investigation that ranges from the United States to Egypt and uncovers murder.

A couple is found dead in a car with broken windows but no shattered glass.

Key suspect has a solid alibi in the murder of a war veteran; but police get a lead by finding a new suspect with a sweet tooth.

A woman who appeared to have taken her own life told her sister that, if anything were to happen to her, there was a note in the china cabinet.

When an aspiring model turns up dead, police suspect her boyfriend. But must dig deeper for clues when he is cleared.