Jacqueline's massive shoulder growth makes it difficult for her to do her favorite hobby of fire spinning; the mysterious bump on James' cheek loves to bleed; Mikalia has possessed a bumpy, smelly mass on her head since birth.

After losing his longtime love, Joe wants the large bumps all over his head removed; the itchy, painful rash on Nisa's ears spreads to her face; Jennifer has dark spots all over her face that nobody is allowed to see.

Cedric has a bump on his eye and a painful lump on his neck that have kept him from working; Katherine's large ear cluster puts her neighborhood watch job at risk; Andrea uses makeup to cover the white spots all over her face and body.

Jimmy's flaky, raised alligator skin feels like an itchy hell, and he wants it cured so he can find love; Djuka is a stubborn guy with a stubborn bump; Talina has hundreds of tumors all over her body, causing embarrassment and discomfort.

Elizabeth's head is covered with giant cauliflower-shaped bumps; Jamaal has been growing a strange knob on the left side of his butt since he was just a boy; Donna's cracking, bleeding skin condition has aged her face and kept her from being social.

Kenny was born with a rare condition that causes hundreds of lumps to grow all over his body; Ebonee covers the tiny bumps on her eyes with sunglasses; Paula's painful and swollen feet ooze a substance that emits a foul odor.

A brain ailment strikes a 22-year-old woman.

Eight-year-old Joshua Wooten is rushed to the ER after his mother finds him collapsed on the bedroom floor. When it is found that Joshua is struggling to breathe and his health continues to decline, doctors are left baffled at what is the cause.

A single mother finds she can no longer walk.

A military wife suffers a sudden paralysis in her leg that defies explanation; doctors discover it may have something to do with her husband's top secret work.

When a young woman goes to the ER with severe abdominal pains, the doctors find a rare and virulent type of cancer that gives her ten years to live.

After moving to a new apartment, the mother of a little girl notices her child is suffering from a burning rash; doctors work to solve what caused it.

A swimmer gets attacks of near-paralytic exhaustion, after which his urine becomes strangely dark; when he has a heart attack, a doctor suspects something sinister.

A college student comes down with a purple rash that literally spreads before his eyes; as his health deteriorates, the doctor must race to find the cause.

A young child blisters after exposure to a few minutes of sun; Doctors make a discovery that the child's inability to sweat is one symptom of a mysterious disorder.

After a young man blows his nose, he becomes violently ill and passes out; his condition progressively worsens while doctors try to diagnose what's wrong before one more sneeze kills him.

A healthy pastor feels like he has had a heart attack every day for years; a friend gives advice and doctors try to solve the mystery.

Decades after a car accident, a woman loses the ability to speak; when her speech returns, she speaks with a foreign accent; one doctor thinks he knows why.

A mother tries to protect her children from their father's hoard; an artist chooses frog, penguins and banana peels over her boyfriend.

Maggie's piles of collections is putting her son's life at risk; Bob's passion for swimming pool parts is pushing his family to the brink.

Traci is pregnant and desperate to move back home, but it's filled floor to ceiling with her mother's stuff.

Kathleen discovers a hoard of mice living in her kitchen; spending the night in a hoard might be the end of a marriage before it even begins.

Medical responders were not able to get in Renee's front door after she had fallen unconscious in her home.

Rick tries to salvage his cluttered home that was nearly destroyed in a house fire; Linda must get her house up to code in 60 days or she will be on the streets.

Traci is pregnant and desperate to move back home, but it's filled floor to ceiling with her mother's stuff.

Kathleen discovers a hoard of mice living in her kitchen; spending the night in a hoard might be the end of a marriage before it even begins.

Medical responders were not able to get in Renee's front door after she had fallen unconscious in her home.

Rick tries to salvage his cluttered home that was nearly destroyed in a house fire; Linda must get her house up to code in 60 days or she will be on the streets.

A mother tries to protect her children from their father's hoard; an artist chooses frog, penguins and banana peels over her boyfriend.

Maggie's piles of collections is putting her son's life at risk; Bob's passion for swimming pool parts is pushing his family to the brink.

After losing 275 lbs., Mikki became a fitness fanatic, but the weight loss left her with a lot of sagging skin; Denise's obesity always made her feel invisible, but after losing 200 lbs. the skin still hinders her from fitting in with her family.

Rebecca lost her weight to be more active with her young son, but the plan backfired because she's now trapped in her excess skin; after his dad died, Sal dropped a ton of weight, but with all the excess skin, he fears he will never become a dad.

Autumn wants to make up for lost time with her son, but the excess skin from major weight loss is holding her back; Cody always pretended to be happy when he was 500-lbs, but after losing the weight, he's covered in skin and is sick of pretending.

Ronnie and Michael Robinette are thriving, but their extra skin is getting in the way; at 64, Renee's excess skin inhibits her from enjoying her relationship and expressing her true self in public.

Dr. Dow and J.J. Virgin are called in to save a pizza addict; consuming 80 times more pizza than an average American.

A woman is addicted to ice cream bars, eating up to 40 bars a day.

A 26 year old man is addicted to maple syrup.

A 34 year old woman in obsessed with eating cheesy potatoes; specialists are called in to help with this damaging and compulsive diet.

Mysti consumes as much as 40 gallons of tartar sauce a year.

A 34-year old diabetic is in need of help to save him from his addiction to cheeseburgers.

After a horrific car accident as a child, Heather's ankle was rebuilt from parts of her body; now it's up to Dr. Vincent to help her walk again.

Dr. Vincent tries to save a man's enormous toe; Dr. Schaeffer has his hands full treating a little boy with big demands; a man with incredibly long toes.

Dr. Schaeffer has to straighten a woman's serpentine foot to reset her life, as Dr. Vincent gets a drummer's foot back on the beat.

Dr. Ebonie's skills are tested as she attempts to diagnose a patient with feet covered in huge, wart-like masses; Dr. Brad is confronted with a mystery case that could be related to the elephant man as well as a patient with paper-thin skin.

Nate sees Dr. Brad for help with the raging calluses on his feet; Savannah has a rare condition that made her big toe grow to an enormous size and hopes Dr. Ebonie can help; Dr. Brad is determined to uncover the mystery behind John's foot growth.

A woman undergoes a risky craniotomy; a man searches for answers.

A teenager is rushed to the hospital after taking aspirin to help alleviate altitude sickness; a woman has pain in her arm that mysteriously spreads.

A woman and her husband decide to start a family after numerous negative pregnancy tests; a man appears to suffer an embolism.

A 3-month-old boy has breathing difficulties; a woman has stomach problems; stepping on a crochet hook causes strange problems for a patient.

An infant shows diverse symptoms; an ER nurse gets a diagnosis of lymphoma, before another symptom reveals her true illness.

Twins battle seemingly unrelated illnesses.

A woman and her husband decide to start a family after numerous negative pregnancy tests; a man appears to suffer an embolism.

A 3-month-old boy has breathing difficulties; a woman has stomach problems; stepping on a crochet hook causes strange problems for a patient.

An infant shows diverse symptoms; an ER nurse gets a diagnosis of lymphoma, before another symptom reveals her true illness.

Twins battle seemingly unrelated illnesses.

A woman undergoes a risky craniotomy; a man searches for answers.

A teenager is rushed to the hospital after taking aspirin to help alleviate altitude sickness; a woman has pain in her arm that mysteriously spreads.

Joyce needs home health care and hasn't left the house in three years; getting to Dr. Now in Houston is just the first step and when he prescribes therapy where Joyce must revisit an unhappy past with her mom; it might be more than she can handle.

At over 700 pounds, Teretha's life is confined to a bed, which is a long way from her former job representing Detroit's healthy eating program; a gastric bypass will hopefully save her life.

Milla is bedridden and dependent on her husband and five kids, who can't resist her unending requests for junk food.

Erica must return to California to continue her weight-loss journey, but she fears past emotional trauma will derail her progress.

Erica regrets not keeping a promise to her mom and hopes her siblings will help, but they're reluctant based on her past failures.

Mother of four LaShanta has been bed-bound for two years, and she relies on her kids to keep her cleaned and fed; her last chance to break the cycle of food addiction is to join Dr. Now's program, but it will take a village to get her out the door.

Holly already has one failed weight loss surgery, so to succeed this time, she must do more than change her eating habits, she must address the childhood issues that continue to plague her.

Holly faces a wedding and an operation; Lashanta is not losing weight and when a car crashes through her living room wall her progress is even slower.

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can't go; Chris' son Garrett, already 600 pounds at age 20, is game to join the journey.

Robin and Garrett started their weight-loss journeys together as aunt and nephew; almost four years later, they're like war buddies, striving to reach their target weights through a combination of shedding pounds and skin removal surgeries.

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can't go; Chris' son Garrett, already 600 pounds at age 20, is game to join the journey.

Robin and Garrett started their weight-loss journeys together as aunt and nephew; almost four years later, they're like war buddies, striving to reach their target weights through a combination of shedding pounds and skin removal surgeries.

Holly faces a wedding and an operation; Lashanta is not losing weight and when a car crashes through her living room wall her progress is even slower.

Pauline's self-destructive behavior continues to be a problem; Chad strives to be a better father and husband as he continues his journey; June's progress stalls when frequent travel and wedding plans cause her to slip back into bad habits.

Sean has a massive growth protruding from his side and skin so stretched it's tearing apart, forcing his mother to change both of their lifestyles before he can be approved for surgery.

Amber is 23, over 600-lbs, and relies on her family and boyfriend for even simple needs; her fear of dying young is so overwhelming that she decides to relocate 2,000 miles in hopes that weight loss surgery will give her life back.

A college graduate with a once-promising career, Justin has eaten his life away to the point of never leaving the house for anything but food; only the help of Dr. Now's weight-loss program can restore his hopes of living a happy, productive life.

After successful sleeve gastrectomy procedures, the Dreier twins collectively lose more than 400 pounds and work toward skin surgeries when a major life event disrupts their world and threatens their progress.

Unable to stand for more than a short period of time, Karina's weight places a burden on her parents and drives a wedge between her and her sister.

Kenae' is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae' turns to food to fill the void.

Despite moving to Houston with the solid support of her boyfriend, Aaron, and her cousin, Jasmine, Tiffany finds it difficult to break the cycle of depressed eating when her two roommates don't join her diet and leave the house every day for work.

Cillas' food addiction is getting in the way of his ability to be there for his fiancée, Jessica, and her three daughters; if he doesn't lose weight soon, he knows he'll lose either his girls or his life.

Cillas must face difficulties from his childhood to progress to his goal weight and set an example for his children; Tiffany struggles to lose weight when financial hardships place a strain on her relationship with her boyfriend, Aaron.

Cillas' food addiction is getting in the way of his ability to be there for his fiancée, Jessica, and her three daughters; if he doesn't lose weight soon, he knows he'll lose either his girls or his life.

Cillas must face difficulties from his childhood to progress to his goal weight and set an example for his children; Tiffany struggles to lose weight when financial hardships place a strain on her relationship with her boyfriend, Aaron.

Despite moving to Houston with the solid support of her boyfriend, Aaron, and her cousin, Jasmine, Tiffany finds it difficult to break the cycle of depressed eating when her two roommates don't join her diet and leave the house every day for work.

Gang warfare and a high population of sick patients keep medical center workers on the move in Los Angeles.

The work of the staff at Baylor University Medical Center in Dallas includes a rodeo champion who was trampled by a bull.

Mentally ill son attacks family; horse throws polo-player.

Stuntman has a bike accident; gang-war stabbing; car-crash victims; man gets burned in a camping accident.

The staff of Wishard Memorial Hospital treat accident victims and victims of violence.

Stabbing victim; drunken teen; shooting victim.

A teenager's bulging tummy and stomach pains; a man's own attempted murder; a college coed stops breathing mysteriously.

A man thinks he's constipated; a young woman in cardiac arrest; a patient's family is clueless.

Bizarre fishing injuries; deadly abdominal pains; teenage victims of a car crash.

A student has difficulty breathing; a man impaled by a shovel; a police officer has a heart attack.

A golfer's life-saving surgery; three nearly naked adults in the ER; a patient accidentally shot by his brother.

A elder playboy has a minor injury that turns deadly; a health fanatic's juice diet leaves him in a comatose state; while juggling multiple critical patients, doctors nearly misdiagnose one who has suddenly deteriorated.

A teenage girl sleeps for weeks at a time, a boy with a brain-crushing skull defies the odds and a unique couple faces a big challenge.

A boy with an extra arm growing out of his back; a woman whose knees bend backwards; a tumor in a woman's eye could soon threaten her life.

A teenager whose body is aging ten times faster than normal, a girl with a massive tumor in the middle of her face needs emergency care and a woman battling a rare disorder can't stop eating.

A man born with an extra set of legs finds out whether they can be surgically removed, doctors attempt to recreate a jaw for a young boy who was mauled by a hyena and a woman living with not one, but two rare conditions.

A teenager with a debilitating skin condition is desperate for relief; a woman struggles to cope with a tumor spreading across her head; a five year old with a rare condition defies the odds.

Three young siblings can't stop eating; a man with a life-threatening face tumor must conquer his fear of surgery; a ground breaking operation to separate conjoined twins; two women born with different disabilities excel in sports and life.

A teenager whose body is aging ten times faster than normal, a girl with a massive tumor in the middle of her face needs emergency care and a woman battling a rare disorder can't stop eating.

A man born with an extra set of legs finds out whether they can be surgically removed, doctors attempt to recreate a jaw for a young boy who was mauled by a hyena and a woman living with not one, but two rare conditions.

A teenager with a debilitating skin condition is desperate for relief; a woman struggles to cope with a tumor spreading across her head; a five year old with a rare condition defies the odds.

Three young siblings can't stop eating; a man with a life-threatening face tumor must conquer his fear of surgery; a ground breaking operation to separate conjoined twins; two women born with different disabilities excel in sports and life.

A teenage girl sleeps for weeks at a time, a boy with a brain-crushing skull defies the odds and a unique couple faces a big challenge.

A boy with an extra arm growing out of his back; a woman whose knees bend backwards; a tumor in a woman's eye could soon threaten her life.

Krystal S. has finally met the man of her dreams, but she won't let herself marry him until she can be sure that she won't become bedridden and force him into the role of caretaker.

Melissa weighs a shocking 673 pounds, and decides to begin her seven-year weight-loss journey toward a healthier life.

Melissa struggles to get to her ideal weight after starting her weight loss journey from 650 pounds with gastric bypass.

Surgery enabled Laura's independence but the complications nearly killed her and she's terrified about the next skin surgery; Chay revealed to her family she was transgender, but living life as an overweight woman.

Latonya found the man she wants to marry; the only problem is that, at almost 700 pounds, she can't walk down the aisle; Latonya doesn't want to give up the food that she's used to, but she may do it for love.

Mother of four LaShanta has been bed-bound for two years, and she relies on her kids to keep her cleaned and fed; her last chance to break the cycle of food addiction is to join Dr. Now's program, but it will take a village to get her out the door.

Lindsey has a white picket fence, a loving husband and a great job, but her food addiction threatens to ruin everything; as she embarks on a weight loss journey to save her life, her husband may provide more harm than support.

Brandon is a talented musician with a beautiful voice and a run-away weight problem; he wants to lose weight and embark on a career; he also wants to take the next step with his girlfriend, Taylor, whom he risks losing if he can't make a change.

Jeanne lives in an unhygienic household with her mother and schizophrenic father; at well over 600 pounds, Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.

Jeanne struggles to care for herself in the aftermath of her dad's death; Brandon strives to get his weight down to feel confident when proposing to his girlfriend, Tayler, and be the man she deserves.

Jeanne lives in an unhygienic household with her mother and schizophrenic father; at well over 600 pounds, Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.

Jeanne struggles to care for herself in the aftermath of her dad's death; Brandon strives to get his weight down to feel confident when proposing to his girlfriend, Tayler, and be the man she deserves.

Brandon is a talented musician with a beautiful voice and a run-away weight problem; he wants to lose weight and embark on a career; he also wants to take the next step with his girlfriend, Taylor, whom he risks losing if he can't make a change.

Brittney has hundreds of tiny bumps over her chest that have destroyed her confidence; John has a nose the size of a plum and leans on his local family clinic for help; Dr. Lee's friend Raquel drops in and brings out her wild side.

Mike's religious beliefs have kept him from seeing a doctor about his huge growth; Kylie has come to love her birthmark and is torn about whether or not to get it removed; Shad's head bump bursts open and smells like death.

Tyler's hands are so dry, cracked and painful that he considers getting them amputated; Ebonee covers the tiny bumps around her eyes with sunglasses; Ralph feels like a cyst factory with painful cysts covering his back.

Kelly has a massive shoulder growth; Erica stabbed her hand with a pencil 45 years ago and believes the lead remains trapped in her palm; Paula's painful and swollen feet ooze a substance that emits the foulest of odors.

Dr. Lee has a surprise for Paula, who has oozing, odoriferous and painful legs; Mike needs to get rid of the bump on his head before two major life events; Amanda feels inadequate for her husband because of the saggy growth on her back.

Alyse has been suffering from a burning rash that feels like it's rubbing away her existence; Terry has become too big for his britches due to a painful butt cheek lipoma; James has demons on his back that are ruining his life.

Krystal, a witch, looks to clear a curse of a cyst from her face; Keven wants to get a butt lipoma removed to get his tush back into a regular shape; Raquel, Dr. Lee's esthetician BFF, almost suffocates Dr. Lee with love and a facial.

J-Fab is the life of the party, but her shoulder bump is seriously cramping her style; Dan is a gentle giant with lumps on his head that add a few inches; Teresa's red face and bumpy nose make her feel like a monster.

Fit guy Alonso wants to show off his progress in the gym, but his 70 lipomas are holding him back; Porscha is a comic book enthusiast with two symmetrical lumps on her face; Jeffrey has a leaky lump named Larry on the back of his head.

Robert carries the weight of providing for his family and the weight of the huge lump on his head; Christina has liquid-filled growths next to her eyes; Felipe, a photographer with a dry skin condition so severe he risks losing his career.

Natasha has ambitions of becoming a model, but her massive ear keloids are keeping her off the runway; eight-year-old Wynter wants her scaly mermaid skin cured; Dr. Lee's bestie, Raquel, needs help with a new product for a private area.

Nhan has an extreme, red birthmark that covers half his face; Debbie worries that her shoulder lump will prematurely age her; Justin is a dude rockin' a man bun, but he's having no fun due to the bumps poking through his scalp.

Jess is a widower looking for love who is stuck with a giant bump on his neck; Cherish developed a leopard-print face during pregnancy; former NFL defensive tackle Marcell Dareus hopes Dr. Lee can tackle his forehead lipoma.

Brent has a tricep bump potentially intertwined in his muscle; Jeb loves the beach but refuses to go because of the massive number of blackheads, pimples, and cysts all over his body; Wanda's mysterious mark that caves in her side.

Don's psoriasis has completely taken over his body; Jeff has a large growth on his spine; Sara has an extra set of breasts and nipples.

Diane has thousands of tumors all over her body; Will fears his shoulder lump will be ripped open; Anthony gets his lump examined; Kal Elle detests her hideous varicose veins.

Pop-up facts and behind-the-scene secrets are revealed; Louis is covered in scaly, dry skin that makes him feel like an alligator; Irais' children are bullied because of the growth on her head; Johnny has a stubborn lump on his back.

Pop-up facts and behind-the-scene secrets are revealed; Belinda's lump on her neck causes her immobility; Nicole needs her armpit lump removed; Adela's chest and back are covered in wisdom spots; Nick foolishly removes a lipoma at home.

Don's psoriasis has completely taken over his body; Jeff has a large growth on his spine; Sara has an extra set of breasts and nipples.

Diane has thousands of tumors all over her body; Will fears his shoulder lump will be ripped open; Anthony gets his lump examined; Kal Elle detests her hideous varicose veins.

Pop-up facts and behind-the-scene secrets are revealed; Louis is covered in scaly, dry skin that makes him feel like an alligator; Irais' children are bullied because of the growth on her head; Johnny has a stubborn lump on his back.

Pop-up facts and behind-the-scene secrets are revealed; Belinda's lump on her neck causes her immobility; Nicole needs her armpit lump removed; Adela's chest and back are covered in wisdom spots; Nick foolishly removes a lipoma at home.

Jess is a widower looking for love who is stuck with a giant bump on his neck; Cherish developed a leopard-print face during pregnancy; former NFL defensive tackle Marcell Dareus hopes Dr. Lee can tackle his forehead lipoma.

Brent has a tricep bump potentially intertwined in his muscle; Jeb loves the beach but refuses to go because of the massive number of blackheads, pimples, and cysts all over his body; Wanda's mysterious mark that caves in her side.

Weeding through rumors for 15 years, a woman is determined to uncover the truth of her biological mother, only to reveal more unexpected family secrets; identical twin sisters search for their biological mother, unsure if she's even alive.

A woman's world was shaken when she discovered she was adopted at 25, and goes onto learn more dramatic revelations; a mother is in a race against time to find her son who she placed for adoption 46 years ago.

A woman searches for her beloved sister who she tried to adopt herself years ago; after a life of longing, a couple is desperate to find the son they placed for adoption fifty years ago when they were teens.

A man searches for his birth mother, whose disappearance when he was 5 years old has haunted him for his entire life; a woman hoping to meet a member of her biological family faces certain realities about her true past.

Nicky Freeman is 40 years old with the body of a 10-year-old, and Gabby Williams is a 6-year-old who is like a newborn, but doctors do not understand why.

Gabby isn't aging and no one knows why; she is eight years old but looks like a three-month old baby; two new cases have emerged that could reveal the mystery.

A woman gives birth prematurely during Hurricane Sandy; an Army soldier coaches his wife's delivery from Afghanistan; a baby delivered in a shopping mall parking lot.

An emergency birth interrupts a wedding; a woman delivers after crashing her car; a baby with a life-threatening condition is born prematurely.

A baby is born twice; a woman in labor is torn apart by a tornado; a wife gives birth at home.

A woman goes into delivery while in a cab; a life-threatening pregnancy; twin sisters have their babies on the same day.

A best friend's offer to be a surrogate results in a life-threatening pregnancy; a woman is bitten by a deadly snake three weeks before her due date; a cupcake famed for inducing labor.

A woman gives birth while trapped in an elevator; two truckers deliver a baby in a diner; a prolapsed umbilical cord threatens a baby's life.

A man injured by a boat propeller; a deadly chain of events; the ER comes to a standstill.

Two gunshot victims; a jogger goes into a coma; the ER staff becomes detectives.

A newlywed's hand gets stuck in a kitchen appliance; a student with an injury down under; a heavy drinker has complications.

A college student's face covered in a plaster mask; a stroke patient's heart keeps stopping and restarting without intervention.

A patient's violent outbursts; a man's heart fails; a patient with severe burns prays for a miracle.

A patient gets drunk to save his life; a patient is stiff after a fall; a patient tasered by the police; a boy impaled by a bottle rocket in the neck.

A newlywed's hand gets stuck in a kitchen appliance; a student with an injury down under; a heavy drinker has complications.

A college student's face covered in a plaster mask; a stroke patient's heart keeps stopping and restarting without intervention.

A patient's violent outbursts; a man's heart fails; a patient with severe burns prays for a miracle.

A patient gets drunk to save his life; a patient is stiff after a fall; a patient tasered by the police; a boy impaled by a bottle rocket in the neck.

A man injured by a boat propeller; a deadly chain of events; the ER comes to a standstill.

Two gunshot victims; a jogger goes into a coma; the ER staff becomes detectives.

An Arizona teenager slips when he tries to jump a fence; a Louisiana bull rider has a run-in with a bull and barely survives.

A fireworks enthusiast buys illegal explosives that backfire; a father falls asleep at the wheel; a pilot ground tests his gyrocopter.

A man's arm is stuck in the basement furnace; a dirt bike rider takes a deadly blow to the neck; a man crawling under his truck to start it makes a nearly fatal mistake.

A father of nine falls deep into an abandoned mine shaft; a Florida teenager comes face-to-face with an 11-foot alligator; a Michigan woman rides a snowmobile for the first time and loses control.

Horseback-riding accident; broken wrist; crash victims.

Cardiac arrest after a DWI crash; ATV accident; drug overdose.

Brain death; life support; organ donation; transplants.

Shooting victim; teen is severely injured.

A woman suffers crippling sinus pains.

Constant respiratory infections and an inability to grow; mysterious spasms and back pain overcome a man's life.

A woman starts growing uncontrollably.

A baby is born with a series of defects; deadly sore throat.

A woman becomes violently ill after a lifetime of good health.

A woman experiences perpetual stomach pain; another faces extreme fatigue and night sweating while pregnant.

A woman craves pickles, is extremely fatigued and can barely stay awake during the day.

A pregnant woman experiences stomach pains and headaches; another woman experiences eye inflammation and joint stiffness.

An ultrasound anomaly worries expectant parents; a biology teacher has a bizarre symptom.

An aspiring actress awakens to an excruciating pain on the right side of her face; Bill experiences nausea and strange tingling in his legs; doctor visits and MRI tests show how these two different cases reveal paralysis.

A woman craves pickles, is extremely fatigued and can barely stay awake during the day.

A pregnant woman experiences stomach pains and headaches; another woman experiences eye inflammation and joint stiffness.

An ultrasound anomaly worries expectant parents; a biology teacher has a bizarre symptom.

An aspiring actress awakens to an excruciating pain on the right side of her face; Bill experiences nausea and strange tingling in his legs; doctor visits and MRI tests show how these two different cases reveal paralysis.

A woman becomes violently ill after a lifetime of good health.

A woman experiences perpetual stomach pain; another faces extreme fatigue and night sweating while pregnant.

Lee's anger issues continue to jeopardize his relationship with Rena and threaten to derail both of their weight-loss journeys; a major life event sends Sarah into a depression that she must pull herself out of if she wants to keep losing weight.

Donald has difficulty walking and relies on his parents to take care of him, so he gets motivated to begin his weight loss journey.

Henry hopes to transform himself for his high school reunion, and gastric bypass is the first step to combating his 715 pounds.

For 23 years, Leneatha has worked as a pharmacy tech at a local hospital; now, she has a young daughter to support, but she's so big that it's hard to move; if Dr Now can't help her stop eating, losing her job could be the least of her worries.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Maja cannot be allowed to undergo bariatric surgery unless she quits emotional eating. However, it seems like Justin may end up making Dr. Now proud.

At over 600 pounds, Angie is trying to get to Houston to see Dr. Nowzaradan, in hope of getting weight loss surgery to save her life; family conflict and disagreements may stop her from being able to do what she needs before she even gets the chance.