A lorry driver is found dead behind the wheel in Camberley, England; police use a revolutionary technique of familial DNA analysis.

In 1976 a woman was left for dead in her home in southern California; despite a major manhunt, the violent killer avoided detection for over four decades.

In 1979 two young boys find their mother's dead body in the living room; how the investigators track down the killer with no solid leads.

From small towns to big cities, virtually every jail and prison in the United States deals with a gang problem; for some, suppressing gangs is a daily challenge that comes with life or death consequences.

A U.S. Marine violates the code and now faces a murder charge; a would-be soccer mom takes up with a violent street gang; an openly gay inmate adheres to the convict code and pays the price.

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A microscopic clue and a stroke of luck help authorities solve the murder of a young woman that took place inside her Jacksonville Beach, Fla., home.

Robert Davis, who was convicted of murdering a woman and her son, claims his confession was coerced and tries to prove he is innocent.

The drug-related death of a 17-year-old girl sheds light on a new class of synthetic drugs that has law enforcement agencies on alert.

Chameleon; Crime Novelist; Lourdes; Death Row Defender.

Musician Sings the Blues; Killer Casanova; Update: Victorio's Gold; Rudolph on the Run; Dress-Up Escape.

Rookie Death; Roswell; Missing Angel; ATV Murders; Murderer's Escape.

Killer Castro; Terri's Killer; Mississippi Hangings; Woody's Millions; Southern Disappearance.

David Lee Kemp; Missing Susan; Nazi War Treasure; Sean Don Con; After Death Visits.

A bombshell more than a decade after the crime reignites the investigation into the death of Sarah Pagel's mother, who was killed when Sarah was 7.

A chance encounter by custom agents leads to a break in the case of a mother who disappeared days before she was supposed to move to a different city with her young son; a witness speaks out 20 years after the incident.

The survivor of a horrible attack is convinced police have the wrong suspect.

When three people are found dead on the same day in a Kentucky town, investigators know it isn't a coincidence; years pass before there's an arrest as the case continues to divide the community.

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From small towns to big cities, virtually every jail and prison in the United States deals with a gang problem; for some, suppressing gangs is a daily challenge that comes with life or death consequences.

A beloved local teacher is brutally attacked in her Pennsylvania home; after 27 years, dedicated investigators trace her killer.

In 2018, two paralegals are shot dead while at work in Scottsdale, Ariz; four more victims are linked to the killing.

A young woman is found beaten to death in Wisconsin in 1984; killer evades detection for decades until a revolutionary DNA method reveals his identity.

The tenth floor of Cuyahoga County Correction Center contains the Special Response Team, or SERT, a tactical unit trained in the use of riot gear, non-lethal weapons and controlling high-risk inmates.

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A thump heard by the children in a Carlsbad, Calif., home is the first clue to a shocking mystery that involves some family secrets.

A 29-year-old woman goes missing.

As detectives struggle to find leads in the murder of a college student, the perpetrator strikes again.

G.I. Guinea Pig; Bank Tunnel; Murder in the Park; Noreen Renier; Unknown Dad.

Maloney's Mickey; Picture Kristen Gone; Coma Comeback; Update: Foster Son; Police Woman Savior; Mystery Cowboy.

Miami Vice; Zel's Odyssey; Missing Rock Star; Image of Guadalupe; Update: Viet Pilot's Daughter; Drunk Driver.

Russian Roulette; Anthrax; Friendly Ghost; Update: Vanished in the Heartland; Scare Tactics.

Fugitive R.N.; Witness for the Prosecution; Doris Duke; Update: NY State Serial Rapist; Gone Fishing; Miracle Child.

When a young, handsome veterinarian is found dead in his home in Montana, the mystery remains unsolved for nearly two decades.

A murder on Valentine's Day leads to a trial with unexpected twists and turns and a surprise ending.

When Matt Landry suddenly disappears, everyone suspects he is in danger; a violent bank robbery leaves police wondering if there is a connection.

Karen Smith is murdered while her 5-year-old son is brutally stabbed and a neighbor says she knows who did it; she later recants her testimony and fights for the suspect's defense.

Friends of accused murderer Robert Durst talk about his recent arrest in New Orleans and his whereabouts over the past 30 years.

The five-year investigation into the death of a retired corrections officer, who was killed by antifreeze poisoning, reveals multiple suspects.

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Police in Southern California were called to a particularly violent murder scene; advances in forensic genealogy finally solved the case.

A young woman is found beaten to death in Wisconsin in 1984; killer evades detection for decades until a revolutionary DNA method reveals his identity.

In 2018, two paralegals are shot dead while at work in Scottsdale, Ariz; four more victims are linked to the killing.

An inmate with a reputation for trouble goes up against a no-nonsense warden; a 71-year-old woman faces conviction for an investment scheme that left nearly 800 victims in its wake; segregating identical twins.

Life inside the Cuyahoga County Correction Center; members of the jail's most predatory gang set their sights on vulnerable prey; an inmate suffers an apparent breakdown.

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The investigation into the death of a pregnant woman just months after she wed her high school sweetheart reveals secret lives and feuds.

A case pits father against son, husband against wife and brother against brother.

When an Iowa woman is attacked while home alone with her three children, the confrontation turns deadly.

The latest in the case of a missing young Oregon woman whose disappearance led to an intense manhunt after a suspect embarked on a two-state crime spree.

Secrets emerge and a family is torn apart when a cop's wife is shot to death in her bed.

When a young woman is found dead near a soccer field in Indiana, detectives try to piece together a puzzle that leads them to an unexpected suspect.

With six people killed and a city under siege, a retired detective tries to figure out how the killings are linked.

A mother's death initially appears to be a suicide, but when investigators start to interview those closest to her, an evil plot emerges.

When a hard-charging boss in Arizona is shot to death, police uncover a complex web of bruised egos in his professional life and a trail of broken hearts in his personal life.

Two sisters determined to fulfill a promise investigate the mystery surrounding their mother's death.

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An inmate with a reputation for trouble goes up against a no-nonsense warden; a 71-year-old woman faces conviction for an investment scheme that left nearly 800 victims in its wake; segregating identical twins.

A beloved local teacher is brutally attacked in her Pennsylvania home; after 27 years, dedicated investigators trace her killer.

In 1979 two young boys find their mother's dead body in the living room; how the investigators track down the killer with no solid leads.

In 1976 a woman was left for dead in her home in southern California; despite a major manhunt, the violent killer avoided detection for over four decades.

The Cuyahoga County Correction Center resides in the heart of Cleveland's downtown; a tip leads to an escape plot; a shank turns up in the kitchen; a younger inmate takes a swing at an officer.

As the oldest prison in California, San Quentin is steeped in a violent history, so it has a set of regulations and procedures to maintain order; inmates often operate under a different code of conduct; gangs control "prison politics."

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A pilot flees following a plane crash, becomes a fugitive and lives a double life for decades.

The murder of a young businessman in Old San Juan, Puerto Rico, marks the start of a 15-year-long hunt to find the killer.

After a 15-year-old girl disappears, investigators discover a creek where the local teenagers hang out that may hold the answer to her disappearance.

When a young woman is found dead in a field on the outskirts of Green Bay, Wis., a fitness tracker helps detectives solve the mystery.

A dancer is murdered in her Virginia home.

G.I. Guinea Pig; Bank Tunnel; Murder in the Park; Noreen Renier; Unknown Dad.

Maloney's Mickey; Picture Kristen Gone; Coma Comeback; Update: Foster Son; Police Woman Savior; Mystery Cowboy.

Miami Vice; Zel's Odyssey; Missing Rock Star; Image of Guadalupe; Update: Viet Pilot's Daughter; Drunk Driver.

Russian Roulette; Anthrax; Friendly Ghost; Update: Vanished in the Heartland; Scare Tactics.

Fugitive R.N.; Witness for the Prosecution; Doris Duke; Update: NY State Serial Rapist; Gone Fishing; Miracle Child.

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The Cuyahoga County Correction Center resides in the heart of Cleveland's downtown; a tip leads to an escape plot; a shank turns up in the kitchen; a younger inmate takes a swing at an officer.

A lorry driver is found dead behind the wheel in Camberley, England; police use a revolutionary technique of familial DNA analysis.

A young woman's body is discovered close to her home in Bath, England; police eventually track down the perpetrator of the heinous attack.

After being reported missing, a young couple's bodies are discovered more than sixty miles apart; how the dedicated investigators eventually find the killer.

Boredom reigns supreme for prisoners who spend endless hours, days and months confined to their cells; some have devised creative ways to pass the time; one inmate is creating a wall mural, but not with real art supplies.

San Quentin's warden says that other than an inmate's release date, visits are the most important things in their lives; for some, visits are rare moments of intimacy; for others, they are business transaction opportunities.

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When a young mother disappears after leaving her infant in the care of her local pastor and his wife, Florida detectives search for her for five years, uncovering a web of secrets and lies.

A recent law school graduate in Georgia who has a promising future disappears without a trace.

Ohio investigators search for answers in the decades-old murder of 10-year-old Amy Mihaljevic; a retracing of Amy's steps from the day of the kidnapping.

Road Map Clues; Past Phone Calls; Miracle Cross; She Finds Fugitives; Phone Call Sister.

Singles Bar; Mary Celeste; Drug Playboy; Update: Coffee Pot Twins; Lost Gause; Update: Li'l Miss; Mystery Baby.

Arizona Souvenir Killer; Amish Hostage Murder; Coin Scam; Postal Crime; Real Dr. Doolittle; Unknown Mom.

John Branion; No One Spared; Leo Koury; Who Saved My Life?; Angels.

Missing Valentine; Perpetual Partners; Update: Baltimore Babynapping; Ranger Bombing Target; Powers of Prayer.

When a graduate student is shot dead outside of her North Carolina home, a 911 caller leads detectives to believe the victim's fiance is the key to solving the case.

When a young woman finds out that her boyfriend might have shot and killed a college football player out of revenge, she struggles with coming forward to officials, fearing she could lose her life.

After a mother of two mysteriously vanishes, a young video gamer shares a tale with detectives that leads to the discovery of a diabolical plot.

A tight-knit Long Island family go to extraordinary lengths to find their missing sister.

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Boredom reigns supreme for prisoners who spend endless hours, days and months confined to their cells; some have devised creative ways to pass the time; one inmate is creating a wall mural, but not with real art supplies.

The police investigation into the Washoe County murder.

In 1994, 42-year-old Le Bich-Thuy is found dead next to her home; decades later, DNA and genealogy technology allow detectives to track down the killer.

A decades-long police investigation includes one of the worst miscarriages of justice in UK history.

Inside San Quentin, gangs, drugs and sheer boredom make up a violent mix; Scanvinski Hymes has been in prison since he was 18 years old; almost 20 years later, he's racked up the highest number of violent offenses in California prison history.

San Quentin has one of the longest histories of violence; whether it's an inmate fresh off the street, a gang dropout in protective custody, or an officer trying to maintain order, they've all fallen victim to violent attacks.

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An investigation of abuse allegations against one of the owners of religious reform school Circle of Hope.

A college student goes missing in broad daylight from her off-campus job at a softball field; investigators receive a mysterious phone call that changes everything.

A murder case considered closed by North Dakota detectives is suddenly reopened when a confidential informant comes forward with a tip about an unlikely suspect.

An in-depth look at a series of mysteries including Johnny Lee Wilson, Tatum's Ghost, Badlands and Daredevil Doe.

Reporter's Trucker; Past Lives; Conway; Doggie Doctor; I.D. Swap.

Campus Murder Expose; Last P.O.W. (Parts 1 & 2); Go Ask Alice; Update: Sweetheart Swindler; Update: Reincarnation.

Starfyre Fugitive; Mother/Son Murder; Fatima (Parts 1& 2); Update: Lucky Lost Love; Lady Killer.

Christmas Party Murder; Myrtles Plantation; California Killing; Asteroids & Meteors; Brief Encounter; Pick Ax.

A woman walks into her home to find her daughter covered in blood; a single drop of blood is the key to finding the attacker.

A couple goes on a scuba-diving vacation in the British Virgin Islands; one of them surfaces but the other does not.

Police initially suspect natural causes as they investigate a man's death, until they learn about an unconventional love triangle, which points the investigation in a new direction.

A love triangle leads to years of stalking, property destruction, threats and murder.

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Inside San Quentin, gangs, drugs and sheer boredom make up a violent mix; Scanvinski Hymes has been in prison since he was 18 years old; almost 20 years later, he's racked up the highest number of violent offenses in California prison history.

In 1973, two young girls are found murdered in the Welsh village of Llandarcy; the killer's identity remains a mystery until 2002.

With the help of familial DNA, detectives are able to track down and capture a serial rapist.

The exhaustive investigation into the murder of Tangie Sims; how genetic genealogy gave investigators the break they'd been waiting for.

An inmate takes drastic action and leaves his cell in a bloody mess; dangerous contraband is found on another inmate at Florida's Santa Rosa Correctional Institution.

A new arrival to the Santa Rosa Correctional Institution raises serious concerns throughout the maximum-security prison; young correctional officer cadets experience the burn as each one takes a pepper spray shot in the eye.

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The homicide of private first class soldier and young mother Karlyn Ramirez; a glimpse into the FBI's crime lab and an in-depth look at how multiple agencies uncovered a plot that spanned several states and prompted suspicions of espionage.

A teenager is convicted of encouraging her boyfriend to kill himself; exclusive interviews with those on both sides of the case.

When a young woman fails to show up to work and her mother rushes to her home to try to find her, what she discovers begins an investigation that leads to a suspect no one imagined.

Gallup Abduction; Fatal Revision (Parts 1, 2 and 3); Wrong Grave.

Twice Burned; Elvis; The Twinless Twin; Where Is Wanda Jean?; Short Walk Home; Rapist MD; Molnar Heir.

Down & Out; Honeymoon Bones; Return From Heaven; Sal and Sally; Women in the Bay; Stahl's Paintings.

Slain Swain; Goldie's Girl; James Van Praagh Parts 1 and 2; Thanks Big Brother; Fugitive Counterfeiter.

Featuring Nashville Hit, Padre Pio Parts 1 and 2, Mystery Clerk, Sharon's Search, and an update on Who Saved My Life.

Road Map Clues; Past Phone Calls; Miracle Cross; She Finds Fugitives; Phone Call Sister.

Singles Bar; Mary Celeste; Drug Playboy; Update: Coffee Pot Twins; Lost Gause; Update: Li'l Miss; Mystery Baby.

Arizona Souvenir Killer; Amish Hostage Murder; Coin Scam; Postal Crime; Real Dr. Doolittle; Unknown Mom.

John Branion; No One Spared; Leo Koury; Who Saved My Life?; Angels.

Missing Valentine; Perpetual Partners; Update: Baltimore Babynapping; Ranger Bombing Target; Powers of Prayer.

An in-depth look at a series of mysteries including Johnny Lee Wilson, Tatum's Ghost, Badlands and Daredevil Doe.

Reporter's Trucker; Past Lives; Conway; Doggie Doctor; I.D. Swap.

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An inmate takes drastic action and leaves his cell in a bloody mess; dangerous contraband is found on another inmate at Florida's Santa Rosa Correctional Institution.

A 69-year-old woman is found brutally murdered in 2011; after the case goes cold, new DNA technology eventually leads detectives to the truth.

Following the decadeslong investigation into the murder of Helene Pruszynski.

How an extensive investigation and revolutionary science of familial DNA revealed an attacker's identity.

A massive search for contraband throughout the facility turns up the heat on two inmates inside the Santa Rosa Correctional Institution; a convict prompts an evacuation when he floods his housing unit.

A cell search inside the maximum-security prison results in some heated words and the discovery of a gang manifesto; inmates express their personal feelings in private to the cameras; one confronts his own mortality.

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When film executive Gavin Smith vanishes, Los Angeles detectives search for clues amid reported sightings and suspicious circumstances.

Keith Morrison reports on an undercover operation in Palm Beach, Florida to save a wife and mother.

Investigators didn't know if Kathy Heckel was a missing person or murder victim; decades later the case is reopened by a new detective.

Chad; Family Man Fugitive; Agatha Christie (Parts 1 & 2); Fritz and the Soldiers.

Bomb Throwing Fugitive; Paisley Hat; Mrs. Millionaire; Kyra's Crisis; Shack Fire.

Vice Cop; Searching for Morgan; Sign From Heaven; Pizza Bandits; Lucie's Last Fare; Loving's Lost Love.

Priest Killer; Chicago Kidnap; Brinks; QI Gong; Update: Ready Teller Robbery; Such is Life.

Diaz Dog Days: Part 1 and 2; Murder by Arson; Baby Broker; Lost Sailor.

When Cara Ryan shoots her ex-husband and accuses him of threatening to kill her, police question her motive.