A successful businesswoman suddenly seems to become possessed by demons; a young college student battles monstrous pain when she grows fingernails out of her hair follicles.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

Jamie's tiredness leads to shocking news; David has joint pain and low stamina.

A young child blisters after exposure to a few minutes of sun; Doctors make a discovery that the child's inability to sweat is one symptom of a mysterious disorder.

After a young man blows his nose, he becomes violently ill and passes out; his condition progressively worsens while doctors try to diagnose what's wrong before one more sneeze kills him.

A healthy pastor feels like he has had a heart attack every day for years; a friend gives advice and doctors try to solve the mystery.

Decades after a car accident, a woman loses the ability to speak; when her speech returns, she speaks with a foreign accent; one doctor thinks he knows why.

A young child blisters after exposure to a few minutes of sun; Doctors make a discovery that the child's inability to sweat is one symptom of a mysterious disorder.

After a young man blows his nose, he becomes violently ill and passes out; his condition progressively worsens while doctors try to diagnose what's wrong before one more sneeze kills him.

A healthy pastor feels like he has had a heart attack every day for years; a friend gives advice and doctors try to solve the mystery.

Decades after a car accident, a woman loses the ability to speak; when her speech returns, she speaks with a foreign accent; one doctor thinks he knows why.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

Jamie's tiredness leads to shocking news; David has joint pain and low stamina.

Former plus-size model and advocate Renee realizes the mortal mistakes she has made as her weight swells to 600 pounds and her health crumbles.

Chuck's second year of weight loss and a new relationship; Paula struggles with juggling many responsibilities along with her weight-loss.

Penny returns to Maryland believing she can lose weight; Tara continues to lose weight and is dating for the first time.

Erica must return to California to continue her weight-loss journey, but she fears past emotional trauma will derail her progress.

Ashley lost over 200 lbs. in Houston, but a family of enablers threatens her progress; Diana has shed 300 lbs., but knee damage may cause her to regain weight.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Ashley hits an emotional wall and is desperate for skin surgery, but she's not losing any weight; after being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

Abi was struggling with his weight before a fluke accident left him mostly paralyzed; bedbound for seven years since then and topping 700 pounds, Abi's only hope for a future with his wife is to get Dr. Now's help to lose weight.

When a regular trip to the grocery store turns into an emergency for the EMTs, Delana must admit how badly she needs Dr. Now's help to lose weight; hopefully her road to recovery will lead her to reconcile with the daughter she's grown apart from.

At age 58, Rose had almost given up and eaten herself to death, but it turned out her family needed her too much for her to go; now she has more than 400 pounds to lose if she wants to get healthy for them, and she's determined to do it.

When a regular trip to the grocery store turns into an emergency for the EMTs, Delana must admit how badly she needs Dr. Now's help to lose weight; hopefully her road to recovery will lead her to reconcile with the daughter she's grown apart from.

At age 58, Rose had almost given up and eaten herself to death, but it turned out her family needed her too much for her to go; now she has more than 400 pounds to lose if she wants to get healthy for them, and she's determined to do it.

Abi was struggling with his weight before a fluke accident left him mostly paralyzed; bedbound for seven years since then and topping 700 pounds, Abi's only hope for a future with his wife is to get Dr. Now's help to lose weight.

Gerard has nearly a hundred lumps varying in size all over his body; Gina has bloody lesions all over; Eric has a large bump on his head that he calls his on and off button.

Traci's confidence has been destroyed after years of bullying from the bumps on her face; Ravon has a unique dangling growth on his leg; David has a large lump.

David is back to see Dr. Lee after she spots a suspicious growth under his eye; Nicole is depressed because of the bumps all over her neck; Steve has a noticeable lump on his forehead; Allen has a growth on his biceps but is terrified of doctors.

Tim has a massive growth on his back that affects his ability to work and socialize; Daniel has debilitating psoriasis that covers most of his body; Gloriana and Yolanda are a mother and daughter duo who have bonded over their bumps.

Inoke has a huge, possibly life-threatening bulge on his shoulder; Delano returns with his back lump after Dr. Lee removed a liter of fluid from it; Reed has hundreds of bumps on his chest that burst and leave nasty scars.

With pandemic safety protocols in place, Dr. Lee reopens her office; Monica has a large birthmark growing on the side of her face; Jackie has a melon-sized lump on the back of her shoulder; Reginald has large, rare growths on the back of his head.

Dr. Lee tries to provide the help Reginald needs to remove the large, rare growths on the back of his head; Che'Re has a prominent bump on her face that has put her in a dark place; Juan has several painful boils on the back of his neck.

Dennis has several giant growths on the back of his head; Juan has a rare condition he hopes Dr. Lee will understand; Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps.

Audrey pops the painful bumps that cover her body so she can feel relief; Felicia has a peculiar-looking dark growth on her forehead; Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat.

John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.

Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.

Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove.

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

Stacey's shoulder growth prevents her from being the playful teacher she once was; Matthew worries that his mysterious shin rash may be dangerous.

Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove.

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

Stacey's shoulder growth prevents her from being the playful teacher she once was; Matthew worries that his mysterious shin rash may be dangerous.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.

Dr. Ebonie and Dr. Brad have their hands full treating a woman with fluid dripping out of her foot; a man born with seven toes on each foot; a barber that dropped a steel door on his big toe 20 years ago has a nail that is completely deformed.

A woman with horribly dislocated toes, a man who walks on his toenails, and a woman who needs fatter feet are all curious cases for Dr. Brad and Dr. Ebonie.

A woman experiences dizzy spells after a vacation; a woman suffers stomach pain and bizarre swelling.

Student experiences crippling pain in his lower back; an adopted child has a lump on her shoulder.

An infant screams in the pool; a mother is struck by a series of headaches.

An infant has an eye problem; a young girl is unusually sweaty.

A man has an upside-down head; a girl's face tumor; triplets undergo surgery; a man with misshapen tumors and giant-sized limbs; a man who eats but can't gain any weight.

A man loses his face to cancer; a baby born with a parasitic tumor; a girl's feet won't stop growing; a boy's face melts away.

In Thailand, a woman has the world's largest hands; an Ethiopian girl has a life-threatening neck tumor; 4-year-old conjoined twins risk surgery; a young woman has a body affected by vitiligo; in Spain, a woman's face is blistering away.

A Brazilian man with an elephant leg; a man is scared stiff; a Thai man could be the tallest man in the word; a child born with an unknown condition; a toddler is covered in hair.

Jasmine is forced to call an ambulance when she experiences abdominal cramps; an emergency c-section reveals a shocking surprise.

Amy's cramps force her to go to a local clinic, where she starts giving birth on the way to the exam room.

Anna cannot believe her eyes when she gives birth to a baby in her kitchen.

Kayla goes to a small-town clinic and gets the news she's in labor; with few supplies and a tornado looming, she must be transferred to another hospital over 100 miles away.

On the day before Halloween, Abbigale gives birth when she didn't know she was pregnant.

Christie suddenly experiences pain at work; her mother makes a shocking discovery at a gas station on the way to the emergency room.

Yesica rushes to the hospital after a holistic healer discovers a baby's heartbeat.

Marisa has never had her period and doctors don't think she will ever be able to have children but when she is rushed to the emergency room, doctors are shocked to see she is in labor.

A Halloween zombie with a problem below the belt mystifies doctors; two unconscious men are involved in an accident, a doctor makes a mistake that amazingly explains a patient's condition.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change; a pregnant woman's life-threatening symptoms need urgent treatment.

A student's head is impaled by a trophy deer's antlers; a semi-conscious car crash victim; a woman with an allergic reaction.

A man injured in a medieval role playing battle has a sword impaled in his head; a critically ill patient is so afraid of germs he won't allow doctors to treat him; two patients with the same life-threatening symptoms.

A Halloween zombie with a problem below the belt mystifies doctors; two unconscious men are involved in an accident, a doctor makes a mistake that amazingly explains a patient's condition.

A woman's face-lift goes terribly wrong; a hospital chaplain's sudden personality change; a pregnant woman's life-threatening symptoms need urgent treatment.

A student's head is impaled by a trophy deer's antlers; a semi-conscious car crash victim; a woman with an allergic reaction.

A man injured in a medieval role playing battle has a sword impaled in his head; a critically ill patient is so afraid of germs he won't allow doctors to treat him; two patients with the same life-threatening symptoms.

On the day before Halloween, Abbigale gives birth when she didn't know she was pregnant.

Christie suddenly experiences pain at work; her mother makes a shocking discovery at a gas station on the way to the emergency room.

Yesica rushes to the hospital after a holistic healer discovers a baby's heartbeat.

Marisa has never had her period and doctors don't think she will ever be able to have children but when she is rushed to the emergency room, doctors are shocked to see she is in labor.

Jennifer and her daughter Marissa are stuck in a co-dependent relationship and, with a combined weight of over 900-lbs., both of their lives are in jeopardy; Jennifer must regain control and save both of their lives before it is too late.

Randy's food addiction dissolved his marriage and keeps him from seeing his daughter, so he endures a rigorous pre-surgery diet surrounded by fast-food temptations to regain control of his life.

At over 700 pounds, Teretha's life is confined to a bed, which is a long way from her former job representing Detroit's healthy eating program; a gastric bypass will hopefully save her life.

At 600 pounds, Ashley has to move home so her mom can help her care for herself and her newborn daughter; Ashley must overcome a lifetime's worth of unfortunate circumstances and get Dr. Now's help in Houston.

Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of with her, but to break the cycle of pathological eating that left him nearly bed-bound, he'll have to face a piece of his past he has always kept secret.

Dominic's life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only Dr. Now can help him learn to face life's challenges without using food to cope.

At 24 years old and over 600 lbs, Megan lives at home with her mom, who cooks for her since Megan can't do much on her own; Megan must travel to Houston to meet Dr Now and change her eating habit or her life may end before it ever begins.

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley learns that Dr Now isn't someone she can lie to like her online friends.

Holly faces a wedding and an operation; Lashanta is not losing weight and when a car crashes through her living room wall her progress is even slower.

Robin and Garrett started their weight-loss journeys together as aunt and nephew; almost four years later, they're like war buddies, striving to reach their target weights through a combination of shedding pounds and skin removal surgeries.

Holly faces a wedding and an operation; Lashanta is not losing weight and when a car crashes through her living room wall her progress is even slower.

Robin and Garrett started their weight-loss journeys together as aunt and nephew; almost four years later, they're like war buddies, striving to reach their target weights through a combination of shedding pounds and skin removal surgeries.

Ashley is 24 and lives alone; her only sources of comfort are food and the relationships she has online; but not a single one of her profiles is real; Ashley learns that Dr Now isn't someone she can lie to like her online friends.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

Milla is bedridden and dependent on her husband and five kids, who can't resist her unending requests for junk food.

Sean has a massive growth protruding from his side and skin so stretched it's tearing apart, forcing his mother to change both of their lifestyles before he can be approved for surgery.

For 23 years, Leneatha has worked as a pharmacy tech at a local hospital; now, she has a young daughter to support, but she's so big that it's hard to move; if Dr Now can't help her stop eating, losing her job could be the least of her worries.

At nearly 1,000 pounds, Samantha is dangerously close to dying; to make matters worse, she's paid to eat by making videos online; if Samantha doesn't overcome her toxic relationship with food, she worries she will leave her daughter motherless.

Twenty years after her father died as the result of a botched weight-loss surgery, Carrie is on the brink of eating herself to death; she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband, Chris.

Thederick has become housebound from eating and only goes outside to greet the ice cream man; after a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.

William was always mobile and fairly athletic -- that is, until he wasn't; it's been years now since a knee injury derailed his sports career, and he's ballooned up over 600 pounds; now, to lose weight he'll have to face up to how bad it's gotten.

Charles replaced one addiction with another when he quit doing hard drugs. Now his BMI is over 100 and he can't stop eating. He needs Dr. Now's help, but with his brother doing everything for him, is he too comfortable to make the trek to Houston?

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

Charles replaced one addiction with another when he quit doing hard drugs. Now his BMI is over 100 and he can't stop eating. He needs Dr. Now's help, but with his brother doing everything for him, is he too comfortable to make the trek to Houston?

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

William was always mobile and fairly athletic -- that is, until he wasn't; it's been years now since a knee injury derailed his sports career, and he's ballooned up over 600 pounds; now, to lose weight he'll have to face up to how bad it's gotten.

A student's problems at school; a 17-year-old mom is separated from her son; teenage pregnancy.

A woman juggles the demands of finals and raising her blind daughter; a 16-year-old prepares to give birth alone.

A gunman opens fire outside a strip club; a street performer's magic trick goes horribly wrong; BMX superstar T.J. Lavin's routine jump has a shocking outcome.

A maintenance worker falls from an iconic hotel sign; a rat bite has horrifying implications for its trainer and a plane crashes on a residential street.

A brutal assault could end a star athlete's career, a 28-year-old man is hit in the head by a flying baseball bat; and a Vegas chef falls asleep with a loaded gun.

Paramedics rescue a 25-year-old man from a burning vehicle; an out-of-control car smashes into the patio of a restaurant; and a Vegas ventriloquist narrowly escapes death in a head-on collision.

A woman with an extremely rare skin disorder looks more than twice her age; a baby undergoes risky surgery to cure a mysterious brain condition; three brothers with the same genetic disorder hope for a miracle.

Doctors operate on a huge neck tumor; an English teen is diagnosed with a rare aging condition; an Indian baby is born with an extra head.

Doctors operate on a huge neck tumor; an English teen is diagnosed with a rare aging condition; an Indian baby is born with an extra head.

A look at a wibbly wobbly man, a Frenchman with a rare shaking condition and an American woman with an enormous stomach tumor.

Kinah's addiction to eating toilet paper threatens her health, and her relationships are also on the line; Nathaniel has taken his love of cars to the extreme; Lisa eats cat hair -- and she just cannot get enough.

Nick and Aubrey's addiction to drinking urine has Nick's mom extremely concerned; Karmello's life has gained new meaning since her addiction to illegal butt injections; Lori's addiction to sleeping with her blow dryer might be affecting someone else.

Tyler's addiction to smelling tuna is getting in the way of finding love; Lacey's addiction to plastic surgery and her cup size has grown; after mourning the loss of her record-setting fingernails, Ayanna still has an addiction.

Brittany's addiction to eating car seat foam forces her family to intervene; Lauren has put her addiction to bodybuilding behind her but has found a new obsession; Asha's addiction to her long locks remains strong, but her health remains in jeopardy.

A collapsing roof, mold and overflowing septic tank has caught the attention of city code enforcement.

Gary's house is so full that he is forced to sleep outside on a makeshift bed.

Kathy's extreme hoarding forced her 12-year-old son to move out of their home.

Severe debt and clutter has Dennis moments away from losing everything; Monte's clothing hoard has destroyed a relationship with her son.

A collapsing roof, mold and overflowing septic tank has caught the attention of city code enforcement.

Gary's house is so full that he is forced to sleep outside on a makeshift bed.

Kathy's extreme hoarding forced her 12-year-old son to move out of their home.

Severe debt and clutter has Dennis moments away from losing everything; Monte's clothing hoard has destroyed a relationship with her son.

Tyler's addiction to smelling tuna is getting in the way of finding love; Lacey's addiction to plastic surgery and her cup size has grown; after mourning the loss of her record-setting fingernails, Ayanna still has an addiction.

Brittany's addiction to eating car seat foam forces her family to intervene; Lauren has put her addiction to bodybuilding behind her but has found a new obsession; Asha's addiction to her long locks remains strong, but her health remains in jeopardy.

A man with a mysterious hard growth on his foot and a dancer who returns for an encore surgery keep Dr. Brad and Dr. Ebonie on their toes.

A man who broke his foot three times and never saw a doctor hopes Dr. Ebonie can provide him with some help; a woman with a strange growth that looks like burnt cauliflower visits Dr. Sarah; one of Dr. Brad's most shocking patients returns.

A grandma-to-be acts as surrogate for her daughter's baby; a very premature baby arrives at a playground; a woman gives birth at home.

A woman goes into delivery while in a cab; a life-threatening pregnancy; twin sisters have their babies on the same day.

A best friend's offer to be a surrogate results in a life-threatening pregnancy; a woman is bitten by a deadly snake three weeks before her due date; a cupcake famed for inducing labor.

A woman gives birth while trapped in an elevator; two truckers deliver a baby in a diner; a prolapsed umbilical cord threatens a baby's life.

Parents notice their 7-month-old son has troubling physical impairments; a woman traveling the world starts experiencing unusual back pain and tingling in her feet.

Diane and Howard have a baby boy with a mystery illness; another doctor sees the newborn and diagnoses a rare and fatal disease, seen less than 100 times.

A newborn looks handicapped; a newlywed wakes to debilitating nausea.

A newborn has an indentation in his chest; another baby exhibits troubling symptoms.

A woman is treated at Queens Medical Center in Honolulu after being dragged by the surf across sharp lava rock.

Trauma center at the University of New Mexico Hospital in Albuquerque.

University of Tennessee Medical Center; digital technology; family support.

An eclectic and talented group of people make up the staff at St. Vincent's Emergency Room.

Sexy salsa dancers get a little too frisky and must sashay their way to the hospital; a woman is in pain after experiencing never-ending arousal.

A man and his wife get a vacuum stuck where it shouldn't be; an ice rink quickie leaves a skater with a bizarre injury and a lifetime of embarrassment; a threesome gives a man an unusual problem.

A boyfriend turns a door knob installation into a sexy chore that ends poorly; a couples' game night ends with a woman in severe pain and extreme worry; a paramedic rescues a young couple that fell into a well.

A pirate throws a party that causes a situation below deck; a couple gets in a tangle that leaves one of them tied up for the night; a woman could be permanently blind if her eyes aren't treated.

Sexy salsa dancers get a little too frisky and must sashay their way to the hospital; a woman is in pain after experiencing never-ending arousal.

A man and his wife get a vacuum stuck where it shouldn't be; an ice rink quickie leaves a skater with a bizarre injury and a lifetime of embarrassment; a threesome gives a man an unusual problem.

A boyfriend turns a door knob installation into a sexy chore that ends poorly; a couples' game night ends with a woman in severe pain and extreme worry; a paramedic rescues a young couple that fell into a well.

A pirate throws a party that causes a situation below deck; a couple gets in a tangle that leaves one of them tied up for the night; a woman could be permanently blind if her eyes aren't treated.

University of Tennessee Medical Center; digital technology; family support.

An eclectic and talented group of people make up the staff at St. Vincent's Emergency Room.

After a difficult childhood with an abusive stepfather and drug-addicted mother, Sarah is fighting for her life at only 24 years old.

Zsaylnn needs to lose weight to be the mother her daughter deserves; her husband loves large women and does not support her goals.

A woman battles severe depression and has not left her Chicago basement in two years; the hope of having a life-changing surgery.

Twins Kandi and Brandi have a combined weight of over 1,100 pounds and fear losing each other to obesity, so they decide to make a change together.

At 670 pounds, Ashley, who lives in her parents' home with her husband, decides she must make a drastic change to save her life and her marriage.

Cindy is resistant to change and spends years creating a world that makes her feel safe; when her friend notices Cindy's health declining rapidly due to her size, she pushes Cindy to move to Houston and see Dr. Now.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Kenae' is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae' turns to food to fill the void.

Vianey and Allen have been on a weight-loss journey together; after Allen's surgery is a success and Vianey's is not, the couple struggle to get back on the same page to save their lives.

After regaining her mobility, Octavia is determined to never be stuck in the bed again, but difficult life circumstances threaten her ability to eat right and stay on track; Aaron is laid low by the death of his father, but true love saves him.

Vianey and Allen have been on a weight-loss journey together; after Allen's surgery is a success and Vianey's is not, the couple struggle to get back on the same page to save their lives.

After regaining her mobility, Octavia is determined to never be stuck in the bed again, but difficult life circumstances threaten her ability to eat right and stay on track; Aaron is laid low by the death of his father, but true love saves him.

Kenae' is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae' turns to food to fill the void.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches. Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort. Sharon has an embarrassing, stinky, squirting cyst under her breast.

Keke is covered in bumps that make her embarrassed to be intimate with her husband; Jim is a widower with two lumps who wants them removed for himself and his late wife; Corey has been labeled a devil worshipper because of his forehead growth.

Monica returns for a second time in hopes that Dr. Lee can remove some more of her face growths; Ken has several large cysts on his head that he has tried to remove on his own; Maranda has a mystery skin sore that causes discomfort.

Corey is a drag queen and has a bump dangling from his booty; Adam has a semi-circle of about a dozen cysts on his head that he covers with a hat; Virginia has large growths on both of her upper arms that make it difficult to travel in her RV.

Terry's nose growth has prevented him from meeting his grandkids; Remi has alligator-like skin and is not used to taking care of herself; Austin has an embarrassing birthmark right next to his eyelid; Mary Jo has a throbbing bump on her neck.

Roger has enormous growths on his nose that drip pus, attract flies, and are so large that he can barely breathe; Sandra and Jessie are sisters who bonded over their many undiagnosed face bumps.

Roger returns with his gigantic nose growths in the hope that Dr. Lee and her colleagues can help before it's too late; Christine has lost her essence due to a large growth on her shoulder; Tiffany has a recurring cyst on her eyelid.

Gabriel has a huge growth on his clavicle but is terrified of surgery; Karen has dealt with painful, scaly feet for 22 years with no diagnosis; Lorne has embarrassing tumors on his face and body and believes this is why he hasn't met the one yet.

Ruben is a personal trainer whose head growth has prevented him from seeing clients; Kaitlin has blue marks and scars up and down her arms due to long-term drug use; Adrian was left with a disfiguring bump on her behind after falling down stairs.

Margarita is a matriarch who has been hiding her armpit lump from her family; Kayla is an aspiring musician with a promising career that her painful eczema has brought to a halt; Bradley has a concerning growth that looks like raw meat on his leg.

Jeremy is a pastor with a hanging growth in an embarrassing location; Evelyn has recurring keloids that have been removed three times and come back bigger each time; Todd has a bump protruding from his forehead.

Tameru is a drag queen, but he has a myriad of cysts that are the real drag; Devon has uneven skin she thinks may be the result of a hysterectomy a decade ago; Amy has large growths all over her head that make her look like a "hot mess."

Jason lost their confidence and motivation due to the large growth on his neck; Shawnell's multiple mystery bumps on her head destroy her self-esteem; Jim's growth protruding off of his nose makes it hard to breathe.