Josh has a large knot on his head resulting from a car crash from 18 years ago; Brittney is covered in mysterious bumps; TJ has a hard, curious lump protruding from his side; Luis has a bump on his shoulder and his daughters fear it's dangerous.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Jason has lost confidence due to the large growth on his neck; Shawnell's mysterious head bumps have destroyed her self-esteem; Jim struggles to breathe around his nose growth.

Roger calls the growth on his shoulder his second head; bubbly teenager Jenna has a big bubble behind her ear; Susan is covered in bumps that get in the way of everyday life.

A woman experiences dizzy spells after a vacation; a woman suffers stomach pain and bizarre swelling.

Student experiences crippling pain in his lower back; an adopted child has a lump on her shoulder.

An infant screams in the pool; a mother is struck by a series of headaches.

An infant has an eye problem; a young girl is unusually sweaty.

Parents notice their 7-month-old son has troubling physical impairments; a woman traveling the world starts experiencing unusual back pain and tingling in her feet.

A young child does not respond to pain; a woman experiences unexplained seizures.

A teenager's hair begins to fall out.

Baby Samantha has surgery to remove congenital cataracts that could lead to blindness; as the months pass, Samantha is unable to roll, crawl or talk, and her head is unusually small for her age; her parents seek help.

A baby's gaze is fixed on the ceiling; a woman's bruise will not disappear.

An elderly woman cannot walk straight; a baby cries incessantly.

A woman's legs may need amputation; one side of a woman's face is numb.

A man gains 100 pounds of water weight.

A woman has pain with her menstrual cycle; growths on body.

A baby has large blisters and a high fever; a teenager begins to gain weight at an alarming rate.

A college student has a large blister; nurse has back spasms.

A teen sleeps for 10 days.

A tumor hides another malady; a marathon runner experiences chronic fatigue.

A woman undergoes a risky craniotomy; a man searches for answers.

A college student has a large blister; nurse has back spasms.

A teen sleeps for 10 days.

A tumor hides another malady; a marathon runner experiences chronic fatigue.

A woman undergoes a risky craniotomy; a man searches for answers.

A woman has pain with her menstrual cycle; growths on body.

A baby has large blisters and a high fever; a teenager begins to gain weight at an alarming rate.

Dr. Schaeffer has to straighten a woman's serpentine foot to reset her life, as Dr. Vincent gets a drummer's foot back on the beat.

Dr. Ebonie's skills are tested as she attempts to diagnose a patient with feet covered in huge, wart-like masses; Dr. Brad is confronted with a mystery case that could be related to the elephant man as well as a patient with paper-thin skin.

Nate sees Dr. Brad for help with the raging calluses on his feet; Savannah has a rare condition that made her big toe grow to an enormous size and hopes Dr. Ebonie can help; Dr. Brad is determined to uncover the mystery behind John's foot growth.

Troy's extra toe causes him pain, and he hopes Dr. Ebonie can provide him with relief; Dr. Brad does his best to untangle a ballet dancer's twisted feet; Ramon turns to Dr. Ebonie for help with the sacks of fluid hanging from his leg and ankle.

Despite having the longest big toes Dr. Brad has ever seen, Anna hopes for the feet she's always wanted; Russell visits Dr. Ebonie with feet that look like hooves; Patty lost most of her foot in an extreme amputation, and she needs Dr. Sarah's help.

Michael visits Dr. Sarah to see if she can help with his twisted toes; Robyn has corns on her feet and hopes Dr. Brad can cut them out so she'll be able to walk pain free once again; Richard sees Dr. Ebonie for issues related to his missing big toe.

Dr. Schaeffer, Dr. Haller and Dr. Vincent deck the halls and hang the mistletoes while spreading holiday cheer and treating shocking new cases.

A woman with a 2-pound mass in her foot; a man with pasta-shaped toenails; a woman with heels like rocks has the doctors scratching their heads and holding their noses.

A man treats his life-size doll like a wife; a woman spends hours a day picking scabs on her body.

Crystal has been eating household cleanser since she was twelve; Samantha tans up to three times a day.

Evan sneaks into bathrooms to collect shower drain hair; Nicole breaks apart walls to eat drywall.

Amy and Becky are addicted to being identical; Jennifer addicted to eating mattresses.

Linda has been married to a 70-foot carnival ride, Bruce, for three years; in 12 years Patrice has consumed approximately half a ton of bricks.

A woman in the UK who is addicted to transforming herself into actress and "Baywatch" beauty Pamela Anderson.

A woman who drinks air freshener every day and a person obsessed with having the world's longest neck.

A man is addicted to covering his body in orthopedic plaster casts; a woman who speaks with psychics at least three times a day to avoid loneliness.

Debbie turned to hoarding after a confession ended her marriage; with illness in her family, Julie hoards to ease the pain.

Phyllis' neighbors are complaining about the trash piling up outside; Faye realizes her hoard is killing her.

Brad's hoarding has taken over his mobile home; Mary has been evicted and has just weeks to clean out her stuff.

Hoarding has destroyed Carol's relationship with her daughter; Amy's years of collecting have turned into a massive hoard.

Milton's compulsion has taken over his life; Louise's unhealthy living conditions are making her cancer prognosis worse.

A collapsing roof, mold and overflowing septic tank has caught the attention of city code enforcement.

Brad's hoarding has taken over his mobile home; Mary has been evicted and has just weeks to clean out her stuff.

Hoarding has destroyed Carol's relationship with her daughter; Amy's years of collecting have turned into a massive hoard.

Milton's compulsion has taken over his life; Louise's unhealthy living conditions are making her cancer prognosis worse.

A collapsing roof, mold and overflowing septic tank has caught the attention of city code enforcement.

Debbie turned to hoarding after a confession ended her marriage; with illness in her family, Julie hoards to ease the pain.

Phyllis' neighbors are complaining about the trash piling up outside; Faye realizes her hoard is killing her.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

A woman battles severe depression and has not left her Chicago basement in two years; the hope of having a life-changing surgery.

Chuck weighs almost 700 pounds; he has had to downsize his business and his wife feels like a single-parent who is ready to leave him.

Having her daughters help bathe her is not how Chrystal pictured parenting but she is so large that there's no other option; Chrystal wants Dr. Now's help but she didn't know that bringing her childhood trauma to light would be part of the deal.

Ryan moved to Montana to keep himself from going down a dark path of drug addiction but his new path may be no less lethal than the last if he can't find a way to curb his eating habits before they kill him.

Paul weighs in at 700 pounds, and his girlfriend struggles with how this limits their ability to live a normal life; he thinks their relationship won't survive if he moves to work with Dr. Now, but prioritizing his own health is the only option.

When Nathan's weight gets in the way of his job as a drama teacher, it's a wake-up call for him; changing his life might mean a falling out with his wife, Amber, who is also overweight, unless she can lose, too.

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky; Lacey's weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

For Julian and his wife, Irma, it was love at first sight; in order to grow old together, Julian will have to overcome the food addiction that made him more than 800 pounds.

Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now's help with a second weight-loss surgery.

For Julian and his wife, Irma, it was love at first sight; in order to grow old together, Julian will have to overcome the food addiction that made him more than 800 pounds.

Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now's help with a second weight-loss surgery.

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky; Lacey's weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

Paula has built a wall around herself to push people away; when she suddenly loses a loved one she can no longer ignore the threat of losing her own life.

A mother of two who is too ashamed of her size to be seen with her children; she is committed to regaining her confidence and being a proud mother.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth; now he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth; now he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Lupe has spent the last 10 years in bed and is totally dependent on her husband, prompting a cross-country move that could save her life or end up backfiring.

At 24-years-old, Bettie Jo is on her way to reaching 700 pounds and relies on her husband for her basic needs.

A woman struggles to make a positive change to be part of her partner and son's lives and turn her life around.

Diana, a once thin and active woman, is now a prisoner to her body and trades the comfort of her apartment for a weight loss journey under the strict authority of her niece.

Tanisha weighs around 600-lbs and she's desperate to survive for her kids and avoid her mother's tragic fate of dying at age 50 from super obesity; now at 32, her future looks grim if she doesn't make a drastic change to save her life.

Maja cannot be allowed to undergo bariatric surgery unless she quits emotional eating. However, it seems like Justin may end up making Dr. Now proud.

There is much to be gained and lost for Brianne in year two of her journey, in which she both loses weight and gains independence; getting back with Erica becomes the top priority for Annjeanette, who chooses love over even her own health.

Right when Angie is starting to succeed in Dr. Now's program, her marriage falls apart and her life is thrown into chaos, but she tries to move ahead alone despite dire difficulties.

Right when Angie starts to succeed in Dr. Now's program, her marriage falls apart and her life is thrown into chaos; Angie moves ahead despite dire difficulties, but when her body starts to break down, Angie fears the worst and faces it alone.

Jeanne struggles to care for herself in the aftermath of her dad's death; Brandon strives to get his weight down to feel confident when proposing to his girlfriend, Tayler, and be the man she deserves.

Right when Angie starts to succeed in Dr. Now's program, her marriage falls apart and her life is thrown into chaos; Angie moves ahead despite dire difficulties, but when her body starts to break down, Angie fears the worst and faces it alone.

Jeanne struggles to care for herself in the aftermath of her dad's death; Brandon strives to get his weight down to feel confident when proposing to his girlfriend, Tayler, and be the man she deserves.

Right when Angie is starting to succeed in Dr. Now's program, her marriage falls apart and her life is thrown into chaos, but she tries to move ahead alone despite dire difficulties.

Nine women try to cope with their incarceration; a woman awaits trial for five years.

A current inmate learns that her son has died in a car crash; an inmate's first Mother's Day behind bars; female inmate almost nine months pregnant.

Pregnant detainees await trial; Jamie, a mother of four struggles for visitation rights; Tanya requests house arrest to prepare for the birth of her son.

Latoya struggles with giving up her baby for adoption; Esther is sent to disciplinary segregation.

Ken's girlfriend is giving him one last chance to clear out; Lea could lose her children if she cannot clean her clutter.

A father and son who both hoard; one faces jail time while the other could lose his newborn son.

Tim's inheritance is dwindling and he risks losing his home; twin brothers Lorrin and Orin face a similar predicament.

An apartment complex with three extreme hoarders; the building is now under strict management.

A mother's battling with hoarding discovers her own daughters compulsion; a family's unity at risk.

Doug stands to lose two houses filled with clutter if he doesn't control his compulsion to collect.

Mike is about to undergo surgery to save his life; the biohazards in his home threaten his recovery.

If Seymour cannot clear his roach-infested home, he will be left homeless when the city condemns it.

A surfer is impaled between the legs; a football player's severe leg pain leads to an unexpected diagnosis; a woman is given a clot-busting drug to cure her stroke, but she has another condition that could cause that same drug to kill her.

A boa constrictor has wrapped around a man's arm and won't let go; a young woman has a severe laceration, but doctors begin to suspect there may be more to her case than the injury; a young man goes into anaphylactic shock after a dinner out.

An urgent care physician must think outside the box to care for two emergencies at once; a woman with abdominal pain receives an unexpected diagnosis; a yoga instructor has a dangerously high temperature for no obvious reason.

A patient gets brought in with a live shark clamped onto his thigh, and he wants to save the shark; complications arise for a woman with a life-threatening condition; a mysterious condition causes a man to pass out.

Police officers bring in a criminal that is comatose; a man found passed out in the snow with no jacket or shoes arrives in the ER and a doctor is faced with a family emergency on her day-off.

A fishing lure embedded in a man's face turns out to be the least of his problems; a pair of unconscious teenagers get brought to the ER, where dramatic family secrets come out; an ER technician collapses and refuses traditional medical treatment.

An urgent care physician must think outside the box to care for two emergencies at once; a woman with abdominal pain receives an unexpected diagnosis; a yoga instructor has a dangerously high temperature for no obvious reason.

A patient gets brought in with a live shark clamped onto his thigh, and he wants to save the shark; complications arise for a woman with a life-threatening condition; a mysterious condition causes a man to pass out.

Police officers bring in a criminal that is comatose; a man found passed out in the snow with no jacket or shoes arrives in the ER and a doctor is faced with a family emergency on her day-off.

A fishing lure embedded in a man's face turns out to be the least of his problems; a pair of unconscious teenagers get brought to the ER, where dramatic family secrets come out; an ER technician collapses and refuses traditional medical treatment.

A surfer is impaled between the legs; a football player's severe leg pain leads to an unexpected diagnosis; a woman is given a clot-busting drug to cure her stroke, but she has another condition that could cause that same drug to kill her.

A boa constrictor has wrapped around a man's arm and won't let go; a young woman has a severe laceration, but doctors begin to suspect there may be more to her case than the injury; a young man goes into anaphylactic shock after a dinner out.

Leonard has an alarming bump hanging off of his arm that looks like it's breaking through the skin; Brandon has several lumps on his head that make him fearful for his life; Jess gets a noticeable lump on her butt after falling down the stairs.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about a huge, intrusive bump on his middle finger; Vinnie has a large, embarrassing birthmark on his neck; Leta has a lump on the back of her thigh that she has been hiding from her fiancée.

Tony has large growths on his nose that impair his breathing; Kevin has a bump in his jawline that is a lady deterrent; Marie has an unsightly lump on her forehead that makes her a hermit; Tommy's leg bump makes it difficult for him to work.

Gerard has nearly a hundred lumps varying in size all over his body; Gina has bloody lesions all over; Eric has a large bump on his head that he calls his on and off button.

Traci's confidence has been destroyed after years of bullying from the bumps on her face; Ravon has a unique dangling growth on his leg; David has a large lump.

David is back to see Dr. Lee after she spots a suspicious growth under his eye; Nicole is depressed because of the bumps all over her neck; Steve has a noticeable lump on his forehead; Allen has a growth on his biceps but is terrified of doctors.

Tim has a massive growth on his back that affects his ability to work and socialize; Daniel has debilitating psoriasis that covers most of his body; Gloriana and Yolanda are a mother and daughter duo who have bonded over their bumps.

Inoke has a huge, possibly life-threatening bulge on his shoulder; Delano returns with his back lump after Dr. Lee removed a liter of fluid from it; Reed has hundreds of bumps on his chest that burst and leave nasty scars.

With pandemic safety protocols in place, Dr. Lee reopens her office; Monica has a large birthmark growing on the side of her face; Jackie has a melon-sized lump on the back of her shoulder; Reginald has large, rare growths on the back of his head.

Dr. Lee tries to provide the help Reginald needs to remove the large, rare growths on the back of his head; Che'Re has a prominent bump on her face that has put her in a dark place; Juan has several painful boils on the back of his neck.

Dennis has several giant growths on the back of his head; Juan has a rare condition he hopes Dr. Lee will understand; Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps.

Audrey pops the painful bumps that cover her body so she can feel relief; Felicia has a peculiar-looking dark growth on her forehead; Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat.

John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.

Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

Audrey pops the painful bumps that cover her body so she can feel relief; Felicia has a peculiar-looking dark growth on her forehead; Krista's excessive sweating is so severe that on any given day she could fill up an entire milk jug with her sweat.

John fears the large lump on his neck could become so big that it may eventually suffocate him; Shoshana is depressed because of the big growth on her forehead; Ashley hopes Dr. Lee can provide some relief from her three painful skin conditions.

Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.

Joanne has been held back from success because of her forehead growth; Shakisaha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

Dr. Lee tries to provide the help Reginald needs to remove the large, rare growths on the back of his head; Che'Re has a prominent bump on her face that has put her in a dark place; Juan has several painful boils on the back of his neck.

Dennis has several giant growths on the back of his head; Juan has a rare condition he hopes Dr. Lee will understand; Natalie searches for answers as to why her body is covered in hundreds of mysterious dark bumps.

A teenager is rushed to the hospital after taking aspirin to help alleviate altitude sickness; a woman has pain in her arm that mysteriously spreads.

A woman and her husband decide to start a family after numerous negative pregnancy tests; a man appears to suffer an embolism.

A 3-month-old boy has breathing difficulties; a woman has stomach problems; stepping on a crochet hook causes strange problems for a patient.

An infant shows diverse symptoms; an ER nurse gets a diagnosis of lymphoma, before another symptom reveals her true illness.

Twins battle seemingly unrelated illnesses.

A couple's baby is born without a heartbeat; a woman experiences excruciating headaches.

A woman has shortness of breath, chest and joint pain, extreme fatigue and cough; strange symptoms appear in an energetic kindergartener.

A baby boy has bouts of vomiting and diarrhea from the day of his birth; a young woman experiences blackouts after she hits puberty.

A college student is misdiagnosed with pneumonia.

An overweight girl experiences dizziness and shortness of breath with any physical exertion.

A baby girl turns blue 30 minutes after her birth.

Mysterious symptoms appear for a man who recently underwent minor surgery.

A new baby is plagued with health problems.

Doctors can't pinpoint the cause of the array of ailments a woman has been suffering from for more than 50 years.

A woman who successfully gives birth after two miscarriages faces challenges.

Diane and Howard have a baby boy with a mystery illness; another doctor sees the newborn and diagnoses a rare and fatal disease, seen less than 100 times.

A newborn looks handicapped; a newlywed wakes to debilitating nausea.

A newborn has an indentation in his chest; another baby exhibits troubling symptoms.

A woman who successfully gives birth after two miscarriages faces challenges.

Diane and Howard have a baby boy with a mystery illness; another doctor sees the newborn and diagnoses a rare and fatal disease, seen less than 100 times.

A newborn looks handicapped; a newlywed wakes to debilitating nausea.

A newborn has an indentation in his chest; another baby exhibits troubling symptoms.

A new baby is plagued with health problems.

Doctors can't pinpoint the cause of the array of ailments a woman has been suffering from for more than 50 years.

Getting too hot can be fatal for twins Andrew and Brandon, who meet Josh, a fellow sufferer of Ectodermal Dysplasia.

Tiffany and Yajaira have Jarcho Levin Syndrome, which malformed their ribs and spines during infancy.

Born with Goldenhar Syndrome, Austin and Elena have been bullied for looking different, and feel isolated from other kids.

Chandra is afflicted by a unknown condition that has left his body riddled with hundreds of tumors; in a race against time to find a cure.

Inside the competitive lives of preteens who eat, sleep and breathe bodybuilding to achieve the perfect physique.

Meet three of the tallest teenagers in America who haven't finished growing.

After Thomas Hicks sold over 200 babies illegally in the 1950s and 1960s, Jane Blasio works to reunite the stolen babies with biological families while trying to unearth secrets about Hicks himself.

Jane discovers a suspicious pattern of babies with extremely low birth weights coming out of the clinic; Chris finds out that Dr. Hicks may have hidden birth records in his mausoleum; Diane hopes to meet her biological father.

Jane and Lisa meet the first Hicks baby, Stephen Dilbeck; Chris and Sallie open the mausoleum in search of birth records rumored to be inside as they work on getting approval of an exhumation.

Stephen Dilbeck gets some shocking information about his birth family from Jane and Lisa; Chris and Sallie work on getting approval of an exhumation that will answer questions for hundreds of Hicks babies.

Jane and Lisa share the news about the exhumation with a group of Hicks babies that have questioned whether Dr. Hicks was in fact their biological father; Sallie and the Hicks babies learn the DNA results.

Wendy and her team encounter unexpected challenges with the exhumation; Sallie struggles emotionally with her decision to exhume; the Hicks babies learn the DNA results; three Hicks babies are connected with biological family.

A woman's world was shaken when she discovered she was adopted at 25, and goes onto learn more dramatic revelations; a mother is in a race against time to find her son who she placed for adoption 46 years ago.

A woman searches for her beloved sister who she tried to adopt herself years ago; after a life of longing, a couple is desperate to find the son they placed for adoption fifty years ago when they were teens.

A man searches for his birth mother, whose disappearance when he was 5 years old has haunted him for his entire life; a woman hoping to meet a member of her biological family faces certain realities about her true past.

A woman searches for her brother, hoping to fulfill a promise she made to her late mother, and discovers a 40-year-old secret about her parents' past; a woman consumed by a lifelong search for her mom finds hope with a new DNA connection.

After learning of her own adoption at a late age, Chris aids a woman determined to unlock the mystery behind her birth story; a desperate mother enlists Lisa's help to locate her first-born son, hoping to reunite him with his full-blooded siblings.

Lisa faces many challenges when she helps a woman locate her father -- starting with his identity; a woman seeks Chris' help to find her mother, hoping the similarities she read in her adoption paperwork are not just a fantasy.

A man searches for his birth mother, whose disappearance when he was 5 years old has haunted him for his entire life; a woman hoping to meet a member of her biological family faces certain realities about her true past.

A woman searches for her brother, hoping to fulfill a promise she made to her late mother, and discovers a 40-year-old secret about her parents' past; a woman consumed by a lifelong search for her mom finds hope with a new DNA connection.

After learning of her own adoption at a late age, Chris aids a woman determined to unlock the mystery behind her birth story; a desperate mother enlists Lisa's help to locate her first-born son, hoping to reunite him with his full-blooded siblings.

Lisa faces many challenges when she helps a woman locate her father -- starting with his identity; a woman seeks Chris' help to find her mother, hoping the similarities she read in her adoption paperwork are not just a fantasy.

A woman's world was shaken when she discovered she was adopted at 25, and goes onto learn more dramatic revelations; a mother is in a race against time to find her son who she placed for adoption 46 years ago.

A woman searches for her beloved sister who she tried to adopt herself years ago; after a life of longing, a couple is desperate to find the son they placed for adoption fifty years ago when they were teens.

Cillas must face difficulties from his childhood to progress to his goal weight and set an example for his children; Tiffany struggles to lose weight when financial hardships place a strain on her relationship with her boyfriend, Aaron.

Laura has used food to cope with her emotions; she is confined to a wheelchair and relies on an oxygen tank to breathe and her husband and mother to survive.

Chay has eaten his way to 600 pounds to cope with the emotional turmoil of his childhood; he loses his emotional support and searches for new strength to take control of his life.

Holly faces a wedding and an operation; Lashanta is not losing weight and when a car crashes through her living room wall her progress is even slower.

Robin and Garrett started their weight-loss journeys together as aunt and nephew; almost four years later, they're like war buddies, striving to reach their target weights through a combination of shedding pounds and skin removal surgeries.

Vianey and Allen have been on a weight-loss journey together; after Allen's surgery is a success and Vianey's is not, the couple struggle to get back on the same page to save their lives.

After regaining her mobility, Octavia is determined to never be stuck in the bed again, but difficult life circumstances threaten her ability to eat right and stay on track; Aaron is laid low by the death of his father, but true love saves him.

At over 700 pounds, Brianne undertakes a weight-loss journey to save her own life; she faces an unexpected challenge to her fragile progress when her husband suffers a heart attack on a birthday she will never forget.