Troy's extra toe causes him pain, and he hopes Dr. Ebonie can provide him with relief; Dr. Brad does his best to untangle a ballet dancer's twisted feet; Ramon turns to Dr. Ebonie for help with the sacks of fluid hanging from his leg and ankle.

Despite having the longest big toes Dr. Brad has ever seen, Anna hopes for the feet she's always wanted; Russell visits Dr. Ebonie with feet that look like hooves; Patty lost most of her foot in an extreme amputation, and she needs Dr. Sarah's help.

Debra has a large, brain-like growth on the side of her head that feels like a sponge, has crevices and emits an odor; Dusten is a cowboy looking to remove the painful lump on his knee; Ramiro has a bump on his jaw that has already been removed once.

Eric hopes Dr. Lee is able to remove the giant growth from his behind; Breanna suffers from itchy dry skin she can't help but scratch; Michael makes jokes, but he knows the bump on his head is anything but funny.

Organ donor recipients share similar symptoms before lapsing into coma; pox outbreak in the Midwest.

A deadly fever spreads in California after an earthquake; a bacterial outbreak forces a giant food recall.

Flu symptoms strike down men in Fort Collins; an elderly woman returns from China with a disease.

A disease that kills 17,000 crows and zoo birds also fills a city's emergency room; an unidentified virus in the Southwest.

The CDC, NYPD and FBI team up to deal with anthrax; a mysterious illness targets young girls.

A surfer is impaled between the legs; a football player's severe leg pain leads to an unexpected diagnosis; a woman is given a clot-busting drug to cure her stroke, but she has another condition that could cause that same drug to kill her.

A boa constrictor has wrapped around a man's arm and won't let go; a young woman has a severe laceration, but doctors begin to suspect there may be more to her case than the injury; a young man goes into anaphylactic shock after a dinner out.

An urgent care physician must think outside the box to care for two emergencies at once; a woman with abdominal pain receives an unexpected diagnosis; a yoga instructor has a dangerously high temperature for no obvious reason.

A patient gets brought in with a live shark clamped onto his thigh, and he wants to save the shark; complications arise for a woman with a life-threatening condition; a mysterious condition causes a man to pass out.

Police officers bring in a criminal that is comatose; a man found passed out in the snow with no jacket or shoes arrives in the ER and a doctor is faced with a family emergency on her day-off.

A fishing lure embedded in a man's face turns out to be the least of his problems; a pair of unconscious teenagers get brought to the ER, where dramatic family secrets come out; an ER technician collapses and refuses traditional medical treatment.

Eileen's secret escalates to a matter of life and death; Dale has packed five houses full of clutter.

When Child Protection Services removes Karen's children from her home, she has 48 hours to clean up or risks losing custody of her kids permanently.

Hot-tempered David moved back in with his 93-year old mother and has quickly filled her home with clutter.

After their mother's death, siblings Aimee, Cheryl and Jimmy are left to deal with a house filled with clutter; they bring the aid of a medium to help locate important documents.

Rhonda's home is filled with items she's found in the dumpster; neighbors are threatening lawsuits.

Compulsive hoarder Valerie risks eviction when her next-door neighbor reports her to the health department; Ann's house is so filled with clutter she has been reduced to a small space in her living room.

Kay denies she is a hoarder but her cluttered home with deadly vermin tells another story.

After their mother's death, siblings Aimee, Cheryl and Jimmy are left to deal with a house filled with clutter; they bring the aid of a medium to help locate important documents.

Rhonda's home is filled with items she's found in the dumpster; neighbors are threatening lawsuits.

Kay denies she is a hoarder but her cluttered home with deadly vermin tells another story.

When Child Protection Services removes Karen's children from her home, she has 48 hours to clean up or risks losing custody of her kids permanently.

Hot-tempered David moved back in with his 93-year old mother and has quickly filled her home with clutter.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

At 24-years-old, Bettie Jo is on her way to reaching 700 pounds and relies on her husband for her basic needs.

Susan, 37-year-old woman, has never lived on her own because of her weight, is finally seeking help to get out on her own.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth; now he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

As an Italian American, Geno was raised with lots of love, family and food; now, he's still living with his mom and eating himself to death, and it's time to make a change; Geno's cousin, Nico, joins the cause; they pledge to lose weight together.

Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth; now he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

As an Italian American, Geno was raised with lots of love, family and food; now, he's still living with his mom and eating himself to death, and it's time to make a change; Geno's cousin, Nico, joins the cause; they pledge to lose weight together.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

Latonya found the man she wants to marry; the only problem is that, at almost 700 pounds, she can't walk down the aisle; Latonya doesn't want to give up the food that she's used to, but she may do it for love.

A woman battles severe depression and has not left her Chicago basement in two years; the hope of having a life-changing surgery.

Olivia suffers an unexpected loss; James strives to reach his goal of skin surgery and have a fulfilling relationship.

Wess gets off to a great start in Dr. Now's program, but when the cravings continue after surgery, Dr. Now sends him to therapy to confront his demons; Wess must ask himself whether he is ready to live his truth as a gay man in small-town Texas.

Syreeta thinks that anyone trying to help has an ulterior motive, but she's gotten so big she desperately needs help; she's learning to let down her guard for her husband, but weight-loss surgery will be tough if she can't learn to trust the surgeon.

Mark sets out with a goal for weight-loss surgery, but as weight loss gets easier, he turns down medical advice and decides to do it on his own; Mark thinks he can lose 500 pounds by himself, but Dr. Now sees this as another excuse not to change.

With her weight spiraling, Stephanie needs her mom's help to care for her three kids; she's at the point where she'll have to lose weight or risk not having the chance to see her kids grow up.

Nothing means more to Chris than his relationship with his daughter, Zoey, but now he feels he is failing her as his weight gain begins to limit his mobility.

Patrick's weight has never been a bother, but now he's so big that it's getting in the way of his relationship with his daughter; if he wants to see her graduate high school, he'll have to reverse course.

Krystal S. has finally met the man of her dreams, but she won't let herself marry him until she can be sure that she won't become bedridden and force him into the role of caretaker.

Patrick's weight has never been a bother, but now he's so big that it's getting in the way of his relationship with his daughter; if he wants to see her graduate high school, he'll have to reverse course.

Krystal S. has finally met the man of her dreams, but she won't let herself marry him until she can be sure that she won't become bedridden and force him into the role of caretaker.

Nothing means more to Chris than his relationship with his daughter, Zoey, but now he feels he is failing her as his weight gain begins to limit his mobility.

Abi was struggling with his weight before a fluke accident left him mostly paralyzed; bedbound for seven years since then and topping 700 pounds, Abi's only hope for a future with his wife is to get Dr. Now's help to lose weight.

Henry hopes to transform himself for his high school reunion, and gastric bypass is the first step to combating his 715 pounds.

Bedridden Marla is so heavy she cannot stand up; she must face the hard truth about her condition and understand the toll it takes on her supportive family.

When a regular trip to the grocery store turns into an emergency for the EMTs, Delana must admit how badly she needs Dr. Now's help to lose weight; hopefully her road to recovery will lead her to reconcile with the daughter she's grown apart from.

At age 58, Rose had almost given up and eaten herself to death, but it turned out her family needed her too much for her to go; now she has more than 400 pounds to lose if she wants to get healthy for them, and she's determined to do it.

William was always mobile and fairly athletic - that is, until he wasn't; it's been years now since a knee injury derailed his sports career, and he's ballooned up over 600 pounds; now, to lose weight he'll have to face up to how bad it's gotten.

Charles replaced one addiction with another when he quit doing hard drugs. Now his BMI is over 100 and he can't stop eating. He needs Dr. Now's help, but with his brother doing everything for him, is he too comfortable to make the trek to Houston?

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

Vianey and Allen are locked in a co-dependent relationship based on a shared love of food; as they head to Houston, they will soon find out if their relationship can handle the strain of growing healthy together.

Vianey and Allen have been on a weight-loss journey together; after Allen's surgery is a success and Vianey's is not, the couple struggle to get back on the same page to save their lives.

Vianey and Allen are locked in a co-dependent relationship based on a shared love of food; as they head to Houston, they will soon find out if their relationship can handle the strain of growing healthy together.

Vianey and Allen have been on a weight-loss journey together; after Allen's surgery is a success and Vianey's is not, the couple struggle to get back on the same page to save their lives.

Shakyia was always chubby, but now she does not leave the house and makes no effort; her older sister rallies her to Houston to meet Dr. Now and lose weight, but she is in for a shock when her mother decides that caring for her is just too much.

A mother mistakes labor pains for kidney stones; after losing weight, a woman discovers she is pregnant.

On the day before Halloween, Abbigale gives birth when she didn't know she was pregnant.

Tiffany thinks the abdominal pain she is having is from a rupturing cyst, but it's actually a child she didn't know she was carrying.

After returning home from spring break, a college freshman begins to suffer painful back cramps but does not realize she's pregnant until she gives birth to a boy.

A pregnant woman suffers strokes and a heart attack.

A newlywed couple is moving cross-country when the young wife, not knowing she is pregnant, discovers she is in labor.

Nicole has a c-section and Mariah refuses to help; Kim goes through a painful labor and delivery; Lemhele and Shaniyah go back to therapy.

Nicole makes a controversial announcement; Kim deals with her grandmother; Shaniyah gets induced.

Kim's boyfriend is released from rehab; Nicole and AJ get married; Shaniyah and Lemhele struggle with two new babies in the house; Lorna has a difficult birth.

An infant screams in the pool; a mother is struck by a series of headaches.

Mysterious pains wrack an active teen's body.

A woman has pain with her menstrual cycle; growths on body.

Doctors can't pinpoint the cause of the array of ailments a woman has been suffering from for more than 50 years.

A teen sleeps for 10 days.

Two-year-old Indonesian chain smoker; young man with facial tumor may not survive surgery; seven-year-old twins attached at the head.

Triplets born with a rare condition need surgery or their brains could be crushed; a boy has legs that have become so large he is unable to move; a soccer star who was born without feet.

Two feet tall woman; real-life Sleeping Beauty; isolated bubble man.

A young boy with a life-threatening neck growth seeks treatment; a baby born with eight limbs undergoes groundbreaking surgery.

A teenager who has been hiding a rare condition undergoes surgery, doctors attempt to diagnose a young girl born with dark hair covering her entire body and a man with tree like growths encasing his hands and feet seeks treatment.

Young Dominican woman cries blood; world's fattes child has insatiable appetite; young girl trapped behind werewolf's face.

A man loses his face to cancer; a baby born with a parasitic tumor; a girl's feet won't stop growing; a boy's face melts away.

A young boy with a life-threatening neck growth seeks treatment; a baby born with eight limbs undergoes groundbreaking surgery.

A teenager who has been hiding a rare condition undergoes surgery, doctors attempt to diagnose a young girl born with dark hair covering her entire body and a man with tree like growths encasing his hands and feet seeks treatment.

Young Dominican woman cries blood; world's fattes child has insatiable appetite; young girl trapped behind werewolf's face.

A man loses his face to cancer; a baby born with a parasitic tumor; a girl's feet won't stop growing; a boy's face melts away.

Triplets born with a rare condition need surgery or their brains could be crushed; a boy has legs that have become so large he is unable to move; a soccer star who was born without feet.

Two feet tall woman; real-life Sleeping Beauty; isolated bubble man.

An eclectic and talented group of people make up the staff at St. Vincent's Emergency Room.

Patients at the University Hospital trauma center in Albuquerque, N.M., often come from great distances.

Cases at University Medical Center in Florida include a 16-year-old track star fighting for her life and a man who kills his brother in a car accident.

Plagued by health problems, Meghan hopes to get weight loss surgery along with her overweight best friend, Vannessa; Vannessa is afraid of trying to lose weight only to fail.

After a painful recovery from bariatric surgery, Meghan works hard to keep best friend Vanessa's diet on track; Vanessa wants the surgery too, but she struggles to maintain a healthy diet because all her groceries come from a local food pantry.

Corey is a young gay man who is just getting back on his feet after being homeless; He has dreams of getting back into college and finding a serious relationship, but he needs to make huge changes if he is going to live his dreams.

After Dr. Procter postponed Corey's bariatric surgery and increased his weight loss target to 25 pounds, Corey tries to stay focused on his diet; a successful blind date provides a welcome boost of confidence.

George is determined to lose weight to win his ex-girlfriend back.

Jennifer started to gain weight after a car accident.

Jasmin needs surgery to help care for her son and ailing mother.

Jessica is 700 pounds and is battling life-threatening illnesses.

A man's itchy rash turns out to be more than just poison oak; a young woman bleeds profusely from the inside of her lip, but there is no obvious cause; a family of three is admitted as car accident victims, but the doctor makes a shocking discovery.

Two separate car crash victims are brought to the ER in their underwear; a woman is acting delusional and refuses to allow the ER staff to touch her; a doctor struggles to diagnose a dehydrated and nauseous 10 year old.

A teenage girl is impaled through the neck on an iron fence; a patient is convinced he's turning into a vampire; a first-year attending physician stands up to a room full of senior specialists to save the life of a critically ill pregnant woman.

The ER is a crime scene when a woman's belly pain is caused by smuggled narcotics; a doctor is mystified by heart attacks occurring the same day in the same family; strange markings on the body of a car crash victim lead to the cause of the accident.

Two seemingly unrelated gunshot wounds lead to a bizarre night in the ER; a senior nurse unravels at the sight of a critical patient, and reveals a shocking secret; a patient's grave symptoms mysteriously disappear whenever the doctor touches him.

A woman comes in with a piece of rebar impaling her thigh; a man brings his girlfriend into the ER for an STD workup; an ER doctor confronts a woman's prejudiced colleagues.

A man passes out from abdominal pain; a woman helps solve the mystery of her estranged father's deadly symptoms; a group of delirious Civil War re-enactment soldiers arrives in the ER.

The ER is a crime scene when a woman's belly pain is caused by smuggled narcotics; a doctor is mystified by heart attacks occurring the same day in the same family; strange markings on the body of a car crash victim lead to the cause of the accident.

Two seemingly unrelated gunshot wounds lead to a bizarre night in the ER; a senior nurse unravels at the sight of a critical patient, and reveals a shocking secret; a patient's grave symptoms mysteriously disappear whenever the doctor touches him.

A woman comes in with a piece of rebar impaling her thigh; a man brings his girlfriend into the ER for an STD workup; an ER doctor confronts a woman's prejudiced colleagues.

A man passes out from abdominal pain; a woman helps solve the mystery of her estranged father's deadly symptoms; a group of delirious Civil War re-enactment soldiers arrives in the ER.

A teenage girl is impaled through the neck on an iron fence; a patient is convinced he's turning into a vampire; a first-year attending physician stands up to a room full of senior specialists to save the life of a critically ill pregnant woman.

Two separate car crash victims are brought to the ER in their underwear; a woman is acting delusional and refuses to allow the ER staff to touch her; a doctor struggles to diagnose a dehydrated and nauseous 10 year old.

A baby's hair appears brittle, and she is slow in developing after a case of whooping cough.

A teenager is wracked with mysterious pains.

Mysterious symptoms appear for a man who recently underwent minor surgery.

A 3-year-old's motor skills begin to deteriorate; a woman experiences fatigue after the birth of her second child.

After moving houses, and months of strange behavior, 11-year-old Sammy stops walking and only hops. Can doctors bring him out of the bizarre world he is slipping into?

A baby has strange spots all over; a dad's muscle weakness.

A woman surviving blindness and albinism suffers another disease.

Dr. Lee faces off with iguana-wrangler Madison's head growths; Chanel suffers from painful cyst tunnels beneath her armpit skin that leak and smell like the food she eats; the dark purple birthmark on Eddie's nose has made him a recluse.

Bob suffers from mysterious open-wound sores all over his body; Virginia's stress-ball-sized lump is such a pain in her neck that she can't wait to have it removed; Ted suffers from flaking, itchy, stucco-like skin and has had no luck finding a cure.

Steven's bump is so large, his daughter thinks he is growing a monster on his back; Catherine's arm lump has grown so big that it's nearly up to her armpit; Ethan suffers from an irritating rash in an uncomfortable and awkward place on his body.

John lost his sight at a young age and soon after began growing lumps on his body. Lynette has hundreds of pebble-sized bumps all over her arms, chest and belly. Gabe cannot imagine going to college with the unsightly mole on the back of his head.

Casey's birthmark covers most of her face, head and neck; James has mysterious massive growths on his inner thigh and lower abdomen; Jerry had to hang up his rock star vocal cords when a lump grew out the side of his throat.

Johnnie's crippling psoriasis keeps him from spending time with his daughter; Aimee has a mohawk of cysts on her head; Edith's face markings and itchy skin condition turn out to be more than she expected.

Kenny was born with a rare condition that causes hundreds of lumps to grow all over his body; Ebonee covers the tiny bumps on her eyes with sunglasses; Paula's painful and swollen feet ooze a substance that emits a foul odor.

Jacqueline's massive shoulder growth makes it difficult for her to do her favorite hobby of fire spinning; the mysterious bump on James' cheek loves to bleed; Mikalia has possessed a bumpy, smelly mass on her head since birth.

After losing his longtime love, Joe wants the large bumps all over his head removed; the itchy, painful rash on Nisa's ears spreads to her face; Jennifer has dark spots all over her face that nobody is allowed to see.

Michael visits Dr. Sarah to see if she can help with his twisted toes. Robyn has corns on her feet and hopes Dr. Brad can cut them out so she'll be able to walk pain free once again. Richard sees Dr. Ebonie for issues related to his missing big toe.

A woman with a 2-pound mass in her foot; a man with pasta-shaped toenails; a woman with heels like rocks has the doctors scratching their heads and holding their noses.

Jacqueline's massive shoulder growth makes it difficult for her to do her favorite hobby of fire spinning; the mysterious bump on James' cheek loves to bleed; Mikalia has possessed a bumpy, smelly mass on her head since birth.

After losing his longtime love, Joe wants the large bumps all over his head removed; the itchy, painful rash on Nisa's ears spreads to her face; Jennifer has dark spots all over her face that nobody is allowed to see.

Michael visits Dr. Sarah to see if she can help with his twisted toes. Robyn has corns on her feet and hopes Dr. Brad can cut them out so she'll be able to walk pain free once again. Richard sees Dr. Ebonie for issues related to his missing big toe.

A woman with a 2-pound mass in her foot; a man with pasta-shaped toenails; a woman with heels like rocks has the doctors scratching their heads and holding their noses.

Johnnie's crippling psoriasis keeps him from spending time with his daughter; Aimee has a mohawk of cysts on her head; Edith's face markings and itchy skin condition turn out to be more than she expected.

Kenny was born with a rare condition that causes hundreds of lumps to grow all over his body; Ebonee covers the tiny bumps on her eyes with sunglasses; Paula's painful and swollen feet ooze a substance that emits a foul odor.

A woman discovers a life-long secret and realizes her biological father does not know she exists; an adopted woman's only hope to find her biological family is through DNA.

Susan aches for a mother-daughter relationship, and searches for both her biological mother and the daughter she placed for adoption as a teen; Tammy is still haunted for never getting to say goodbye to the son she birthed over 30 years ago.

A man who always longed for a sibling stumbles upon a shocking family murder; Lisa meets a woman eager to find her biological mother, but she also finds information that changes her view of the past.

Two sisters search for the father who vanished from their lives when they were very young; a woman discovers that her musical talent can be attributed to her biological mother.

Eight women cope with their incarceration in Gwinnett County Jail; one woman prepares for her release.

Nine women try to cope with their incarceration; a woman awaits trial for five years.

A young mother faces the idea of seeing her son through visitation glass; an inmate promises not to return but finds herself back in jail; a desperate inmate only needs a small amount of money to get released.

A current inmate learns that her son has died in a car crash; an inmate's first Mother's Day behind bars; female inmate almost nine months pregnant.

Kendra Herrin and her sister, Maliyah, were born attached at the abdomen and pelvis; doctors use a groundbreaking surgical procedure to separate the girls.

Follows Maria and Teresa Tapia, conjoined twins from the Dominican Republic, as they travel to Richmond, Virginia to undergo separation surgery.

Stories of three very different sets of twins incorporate their lives since being surgically separated.

Louise and her lavish hoarding could end up on the street.

A woman has been sent to jail four times for her hoarding; people purchase a house.

As the lead singer for a rock bands, Kelly Jay has lived quite a life and he has collected a massive hoard to prove it; with his family ready to call it quits, Kelly must choose between his clutter and the people he loves.

Milton's compulsion has taken over his life; Louise's unhealthy living conditions are making her cancer prognosis worse.

A collapsing roof, mold and overflowing septic tank has caught the attention of city code enforcement.

A father and son who both hoard; one faces jail time while the other could lose his newborn son.

If Seymour cannot clear his roach-infested home, he will be left homeless when the city condemns it.

Milton's compulsion has taken over his life; Louise's unhealthy living conditions are making her cancer prognosis worse.

A collapsing roof, mold and overflowing septic tank has caught the attention of city code enforcement.

A father and son who both hoard; one faces jail time while the other could lose his newborn son.

If Seymour cannot clear his roach-infested home, he will be left homeless when the city condemns it.

A woman has been sent to jail four times for her hoarding; people purchase a house.

As the lead singer for a rock bands, Kelly Jay has lived quite a life and he has collected a massive hoard to prove it; with his family ready to call it quits, Kelly must choose between his clutter and the people he loves.

Tanisha weighs around 600-lbs and she's desperate to survive for her kids and avoid her mother's tragic fate of dying at age 50 from super obesity; now at 32, her future looks grim if she doesn't make a drastic change to save her life.

A mother of two who is too ashamed of her size to be seen with her children; she is committed to regaining her confidence and being a proud mother.

Penny returns to Maryland believing she can lose weight; Tara continues to lose weight and is dating for the first time.

Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden; Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live.

Cynthia, a single mother focused on raising five kids, comes to realize what her death would mean for their future.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

Diana, a once thin and active woman, is now a prisoner to her body and trades the comfort of her apartment for a weight loss journey under the strict authority of her niece.

James becomes bedridden, unable to stand and can barely move his legs; Holly and Mark prepare for skin removal surgery.

Weighing over 700-lbs, Nicole is on the verge of leaving her two young children motherless; trying to survive a family of addicts, she commits to Dr. Nowzaradan's diet program, but crisis threatens to derail all her hopes for weight-loss.

Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of with her, but to break the cycle of pathological eating that left him nearly bed-bound, he'll have to face a piece of his past he has always kept secret.

Weighing over 700-lbs, Nicole is on the verge of leaving her two young children motherless; trying to survive a family of addicts, she commits to Dr. Nowzaradan's diet program, but crisis threatens to derail all her hopes for weight-loss.

Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of with her, but to break the cycle of pathological eating that left him nearly bed-bound, he'll have to face a piece of his past he has always kept secret.

James becomes bedridden, unable to stand and can barely move his legs; Holly and Mark prepare for skin removal surgery.

When Travis gets too big to walk down the aisle, he promises to give his wife a proper wedding; he gains more weight, leaving Dr Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.

Randy's food addiction dissolved his marriage and keeps him from seeing his daughter, so he endures a rigorous pre-surgery diet surrounded by fast-food temptations to regain control of his life.

At 650 pounds, Gideon's weight prohibits him from working, making him completely dependent on his exhausted wife.

Kirsten is close to losing all her mobility, and while she's trying to control of her obesity, she's also in danger of losing her troubled son.

Michael's massive body has left him dependent upon his family, and he must learn to control his anger issues around food, lose weight and address the root of his issues or risk losing everything.

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can't go; Chris' son Garrett, already 600 pounds at age 20, is game to join the journey.

Nathan is shedding pounds and heading back to work as a teacher following his weight-loss surgery; however, his wife Amber can't seem to do the same as she struggles to qualify for a second surgery to update one she had years ago.

Weight loss leads to exciting things when Julian and his wife Irma adopt a baby, but fatherhood might distract Julian from his goals; Cindy needs to change her attitude to lose some weight.