James becomes bedridden, unable to stand and can barely move his legs; Holly and Mark prepare for skin removal surgery.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

Constant respiratory infections and an inability to grow; mysterious spasms and back pain overcome a man's life.

Harry is born healthy but his body starts transforming; Sadie is on the brink of starvation.

A girl is born with shocking deformities; a college student suffers from fluid around his heart and lungs.

A successful businesswoman suddenly seems to become possessed by demons; a young college student battles monstrous pain when she grows fingernails out of her hair follicles.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

A woman believes her neighbors want to kill her; a man is near death after an arrow pierces his chest; two women with swollen abdomens refuse to explain the cause of their pain.

A circus sword-swallower suffers from a persistent case of hiccups; a mother and daughter mysteriously collapse in the ER; a woman loses control of her legs at her daughter's graduation.

An ER doctor's friend arrives at the hospital combative and out of control; a cyclist's throat is torn open when a driver opens a car door in her path; a nursing student is found passed out on the hospital floor.

A young girl is mysteriously paralyzed from the waist down; a young man complains of a splitting headache; a bride-to-be has appendicitis on her wedding day.

Megan is a 33-year-old alcoholic with social anxiety and a troubled past.

Phil is a 58-year-old meth user whose addiction spans over three decades.

Theresa is a homeless alcoholic whose addiction puts her life at risk.

Heroin addicts that live in a tent.

Property investors purchase a house that is occupied by a hoarder; rat infestation compromises the building's foundation.

Jessica is a little person with dangerous toppling piles of clutter; along with her mother she has filled her entire home.

After being the target of a school shooting a former principal's life has changed; paralyzed by PTSD and hoarding Wayne has abandoned his family.

A wife has transformed one couple's home into a heap of trash; on the verge of foreclosure.

Property investors purchase a house that is occupied by a hoarder; rat infestation compromises the building's foundation.

Jessica is a little person with dangerous toppling piles of clutter; along with her mother she has filled her entire home.

After being the target of a school shooting a former principal's life has changed; paralyzed by PTSD and hoarding Wayne has abandoned his family.

A wife has transformed one couple's home into a heap of trash; on the verge of foreclosure.

Theresa is a homeless alcoholic whose addiction puts her life at risk.

Heroin addicts that live in a tent.

With explosive growth comes shootings, stabbings and car crashes.

Kansas City's MAST, one of the most effective ambulance services in the world, covers 400 miles in two states.

The paramedics of REMSA in Reno, Nev., are busy tending to residents and tourists.

The CDC, NYPD and FBI team up to deal with anthrax; a mysterious illness targets young girls.

Organ donor recipients share similar symptoms before lapsing into coma; pox outbreak in the Midwest.

A disease that kills 17,000 crows and zoo birds also fills a city's emergency room; an unidentified virus in the Southwest.

Deadly parasites attack a 9-year-old hockey player, a computer programmer and a marathon runner.

A mass of decaying worms is discovered in a dance instructor's colon; a vacationer suffers headaches and a seizure; parasites get under a scientist's skin.

A parasite attacks a schoolteacher from the inside out; a dancer becomes concerned when her allergic outbreaks become lumpy and infected.

A 3-year-old girl loses a third of her body weight due to extreme bouts of vomiting and diarrhea.

Rebecca lost her weight to be more active with her young son, but the plan backfired because she's now trapped in her excess skin; after his dad died, Sal dropped a ton of weight, but with all the excess skin, he fears he will never become a dad.

Autumn wants to make up for lost time with her son, but the excess skin from major weight loss is holding her back; Cody always pretended to be happy when he was 500-lbs, but after losing the weight, he's covered in skin and is sick of pretending.

Ronnie and Michael Robinette are thriving, but their extra skin is getting in the way; at 64, Renee's excess skin inhibits her from enjoying her relationship and expressing her true self in public.

Tamika finds a partner who makes her feel happy, but she feels uncomfortable due to her excess skin; Emilly blames herself for her son's weight gain, and, now, they both struggle with the pain loose skin has brought into their lives.

Brittany lands in the ER after losing a sex toy in her rectum; Buddy sees Dr. Carothers when he gets a bug in his ear; a pre-teen is brought in to see Dr. Mellick after getting impaled by a massive splinter; Zion has an earring stuck in his ear.

A pregnant Kayla is rushed to the ER for abdominal pain, but Dr. Crawford finds something; an entire bike brake is embedded in Jasmine's thigh; Mary has a fingernail stuck in her ear; Destiny's mouth smells like decaying flesh.

Doctor Crawford needs to remove a barbed nail embedded deeply in the forearm of a patient; Doctor Mellick must meticulously extract an unexpected item from an eye.

Stephen's large, bulbous nose gets him unwanted attention; Veronica wants to be free of secrets, including the bump on her butt crack; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove himself.

Brittany lands in the ER after losing a sex toy in her rectum; Buddy sees Dr. Carothers when he gets a bug in his ear; a pre-teen is brought in to see Dr. Mellick after getting impaled by a massive splinter; Zion has an earring stuck in his ear.

A pregnant Kayla is rushed to the ER for abdominal pain, but Dr. Crawford finds something; an entire bike brake is embedded in Jasmine's thigh; Mary has a fingernail stuck in her ear; Destiny's mouth smells like decaying flesh.

Doctor Crawford needs to remove a barbed nail embedded deeply in the forearm of a patient; Doctor Mellick must meticulously extract an unexpected item from an eye.

Stephen's large, bulbous nose gets him unwanted attention; Veronica wants to be free of secrets, including the bump on her butt crack; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove himself.

Ronnie and Michael Robinette are thriving, but their extra skin is getting in the way; at 64, Renee's excess skin inhibits her from enjoying her relationship and expressing her true self in public.

Tamika finds a partner who makes her feel happy, but she feels uncomfortable due to her excess skin; Emilly blames herself for her son's weight gain, and, now, they both struggle with the pain loose skin has brought into their lives.

Weighing over 700-lbs, Nicole is on the verge of leaving her two young children motherless; trying to survive a family of addicts, she commits to Dr. Nowzaradan's diet program, but crisis threatens to derail all her hopes for weight-loss.

An 800-pound man who lost his job and is mostly housebound looks to find the strength to face his past and save his own life.

A woman struggles to make a positive change to be part of her partner and son's lives and turn her life around.

Kirsten is close to losing all her mobility, and while she's trying to control of her obesity, she's also in danger of losing her troubled son.

Michael's massive body has left him dependent upon his family, and he must learn to control his anger issues around food, lose weight and address the root of his issues or risk losing everything.

Tanisha weighs around 600-lbs and she's desperate to survive for her kids and avoid her mother's tragic fate of dying at age 50 from super obesity; now at 32, her future looks grim if she doesn't make a drastic change to save her life.

Most of the extreme weight on Tracey's body resides in her shockingly misshapen legs, which are massive with severe lymphedema, and gastric surgery is her only chance of survival; Brenda and Melissa prepare for skin removal surgery.

Steven Assanti weighs nearly 800 pounds and his brother Justin almost 600 pounds, and although they can't stand each other, their father packs up the family to travel across the country and seek help.

After a year on a weight loss program, Steven remains completely non-compliant and Justin focuses on a new career instead of his diet, but time is quickly running out for surgery.

After meeting and falling in love at a bariatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their relationship and their lives.

After a year on a weight loss program, Steven remains completely non-compliant and Justin focuses on a new career instead of his diet, but time is quickly running out for surgery.

After meeting and falling in love at a bariatric rehab center, Lee and Rena are battling health and anger issues while taking a desperate, second attempt to save their relationship and their lives.

Steven Assanti weighs nearly 800 pounds and his brother Justin almost 600 pounds, and although they can't stand each other, their father packs up the family to travel across the country and seek help.

Robert has a small keloid on his ear and a large, snakelike keloid on the back of his head that has been removed and returned three times; Angela has four growths on her head and hides away from those she loves out of embarrassment.

Robert is back to see if Dr. Lee and Dr. Umar can remove his recurring head keloid for good; Justice has small lesions all over her body; Mike has hundreds of lipomas that bring him great discomfort.

Debra has a large, brain-like growth on the side of her head that feels like a sponge, has crevices and emits an odor; Dusten is a cowboy looking to remove the painful lump on his knee; Ramiro has a bump on his jaw that has already been removed once.

Eric hopes Dr. Lee is able to remove the giant growth from his behind; Breanna suffers from itchy dry skin she can't help but scratch; Michael makes jokes, but he knows the bump on his head is anything but funny.

Robert has thousands of unique bumps on his arms that Dr. Lee has never seen; Alexis has a painful cheek cyst that oozes and has a pungent odor; Stuart's cluster of back bumps disgusts his wife but thrills Dr. Lee.

Elaine calls the growth on her love handle her third breast; Jessica's cyst is close to her eye and could be dangerous for Dr. Lee to remove; Dwayne wants his nose bumps removed, but he may not be able to make it through the pain of the procedure.

Dr. Lee faces off with iguana-wrangler Madison's head growths; Chanel suffers from painful cyst tunnels beneath her armpit skin that leak and smell like the food she eats; the dark purple birthmark on Eddie's nose has made him a recluse.

Bob suffers from mysterious open-wound sores all over his body; Virginia's stress-ball-sized lump is such a pain in her neck that she can't wait to have it removed; Ted suffers from flaking, itchy, stucco-like skin and has had no luck finding a cure.

Steven's bump is so large, his daughter thinks he is growing a monster on his back; Catherine's arm lump has grown so big that it's nearly up to her armpit; Ethan suffers from an irritating rash in an uncomfortable and awkward place on his body.

John lost his sight at a young age and soon after began growing lumps on his body. Lynette has hundreds of pebble-sized bumps all over her arms, chest and belly. Gabe cannot imagine going to college with the unsightly mole on the back of his head.

Casey's birthmark covers most of her face, head and neck; James has mysterious massive growths on his inner thigh and lower abdomen; Jerry had to hang up his rock star vocal cords when a lump grew out the side of his throat.

Johnnie's crippling psoriasis keeps him from spending time with his daughter; Aimee has a mohawk of cysts on her head; Edith's face markings and itchy skin condition turn out to be more than she expected.

Elizabeth's head is covered with giant cauliflower-shaped bumps; Jamaal has been growing a strange knob on the left side of his butt since he was just a boy; Donna's cracking, bleeding skin condition has aged her face and kept her from being social.

Natasha has ambitions of becoming a model, but her massive ear keloids are keeping her off the runway; eight-year-old Wynter wants her scaly mermaid skin cured; Dr. Lee's bestie, Raquel, needs help with a new product for a private area.

Jen has growths on her ears that cause her depression, pain and vertigo; Juliet is under distress because of the bumps on her neck and chest; Gerald has a lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about his finger bump; Vinnie has a large birthmark on his neck; Leta has a lump on the back of her thigh.

Taylor has a large bump at the base of her spine; John jokes about hip lump, but it's no laughing matter; Noelle wants her stretched ears repaired; new pop-up facts.

All-new juicy pop-up facts and behind-the-scenes secrets.

Jen has growths on her ears that cause her depression, pain and vertigo; Juliet is under distress because of the bumps on her neck and chest; Gerald has a lump on his middle finger.

Gerald is back to see Dr. Lee and a hand specialist about his finger bump; Vinnie has a large birthmark on his neck; Leta has a lump on the back of her thigh.

Taylor has a large bump at the base of her spine; John jokes about hip lump, but it's no laughing matter; Noelle wants her stretched ears repaired; new pop-up facts.

All-new juicy pop-up facts and behind-the-scenes secrets.

Elizabeth's head is covered with giant cauliflower-shaped bumps; Jamaal has been growing a strange knob on the left side of his butt since he was just a boy; Donna's cracking, bleeding skin condition has aged her face and kept her from being social.

Natasha has ambitions of becoming a model, but her massive ear keloids are keeping her off the runway; eight-year-old Wynter wants her scaly mermaid skin cured; Dr. Lee's bestie, Raquel, needs help with a new product for a private area.

A gunman opens fire outside a strip club; a street performer's magic trick goes horribly wrong; BMX superstar T.J. Lavin's routine jump has a shocking outcome.

A maintenance worker falls from an iconic hotel sign; a rat bite has horrifying implications for its trainer and a plane crashes on a residential street.

A shootout leaves a police officer clinging to life; a cowboy and cupid help a she-devil in distress; a zip-line guide falls 80 feet to the canyon floor.

Doctors retrieve a stolen Rolex from a very private spot; a pick-up turns deadly when a cabbie is shot multiple times; a dirt-bike accident in the desert leaves a 52-year-old thrill-seeker clinging to life.

A couple longs to find the daughter they had as young teens; a woman learns her birth was a secret; taking place live, a bride and groom reveal a momentous surprise to their wedding guests and someone gets reunited with a long-lost family member.

A woman whose daughter perished in a car accident hopes to find comfort in locating her granddaughter, who was placed for adoption 26 years ago; a woman yearning to meet her birth mother is stunned by an unlikely figure in the search.

Two brothers navigate a painful past as they search for the family they've longed for their entire lives, and their journey reopens decades-old family mysteries about their birth mother, twin siblings and a baby who was only rumored to exist.

Lisa meets a woman who was left on a curb by her mother when she was just four years old; Chris uncovers stunning information for a woman searching for her family that leads to an unexpected reunion.

A man who always longed for a sibling stumbles upon a shocking family murder; Lisa meets a woman eager to find her biological mother, but she also finds information that changes her view of the past.

A woman and her out of control obsession with bikinis, sweaters and dresses.

Tammy is forced to eat her meals in her car; her sick father is unable to return home from the hospital.

Sharon gets caught stealing from her neighbors; Len must choose between his hoarding and his daughter.

Debbie lost the company of her four children to hoarding; Chip's family of six is forced to live in sixteen hundred square feet of living space.

Patti's extreme hoarding has made it impossible for her daughter to live with her; Jonathan's obsession keeps his three-year-old son from coming in the door.

Kinah's addiction to eating toilet paper threatens her health, and her relationships are also on the line; Nathaniel has taken his love of cars to the extreme; Lisa eats cat hair -- and she just cannot get enough.

Nick and Aubrey's addiction to drinking urine has Nick's mom extremely concerned; Karmello's life has gained new meaning since her addiction to illegal butt injections; Lori's addiction to sleeping with her blow-dryer might be affecting someone else.

Tyler's addiction to smelling tuna is getting in the way of finding love; Lacey's addiction to plastic surgery and her cup size has grown; after mourning the loss of her record-setting fingernails, Ayanna still has an addiction.

Brittany's addiction to eating car seat foam forces her family to intervene; Lauren has put her addiction to bodybuilding behind her but has found a new obsession; Asha's addiction to her long locks remains strong, but her health remains in jeopardy.

Kinah's addiction to eating toilet paper threatens her health, and her relationships are also on the line; Nathaniel has taken his love of cars to the extreme; Lisa eats cat hair -- and she just cannot get enough.

Nick and Aubrey's addiction to drinking urine has Nick's mom extremely concerned; Karmello's life has gained new meaning since her addiction to illegal butt injections; Lori's addiction to sleeping with her blow-dryer might be affecting someone else.

Tyler's addiction to smelling tuna is getting in the way of finding love; Lacey's addiction to plastic surgery and her cup size has grown; after mourning the loss of her record-setting fingernails, Ayanna still has an addiction.

Brittany's addiction to eating car seat foam forces her family to intervene; Lauren has put her addiction to bodybuilding behind her but has found a new obsession; Asha's addiction to her long locks remains strong, but her health remains in jeopardy.

Debbie lost the company of her four children to hoarding; Chip's family of six is forced to live in sixteen hundred square feet of living space.

Patti's extreme hoarding has made it impossible for her daughter to live with her; Jonathan's obsession keeps his three-year-old son from coming in the door.

Lee's anger issues continue to jeopardize his relationship with Rena and threaten to derail both of their weight-loss journeys; a major life event sends Sarah into a depression that she must pull herself out of if she wants to keep losing weight.

Diagnosed with cancer and battling depression, Bettie Jo finds out she's pregnant, and she must find a way to cope with the help of her husband; Susan suffers a major setback after surgery for her excess skin.

Joe made a drastic turn from being suicidal and is now ready for marriage, but the reality of more weight loss could stop him from achieving his dream.

In the fourth year of his weight-loss journey, Sean struggles to get past the loss of his mother and live on his own; Dr. Now intervenes to control Sean's eating for a time.

Liz has gone from being bedbound with lymphedemas on both legs to standing and walking; if Jenn and Marissa can't get along as mother and daughter to lose weight, they'll have to proceed apart; with facts and bonus scenes.

For Milla Clark, after three years and five surgeries, success would mean beating the odds and becoming one of Dr. Nowzaradan's most impressive weight-loss patients, but failure would mean slipping back to the bedbound life.

After a lifelong struggle with obesity, the three Perrio siblings travel to Houston in a last-chance journey to lose weight.

Tammy faces a tough choice when her husband wants her back, but only if she moves away from Houston and Dr. Now's program; Karina's weight loss begins to slow, but she finds happiness dating a guy Dr. Now is surprised to see in his clinic again.

Erica's success on her weight-loss journey is derailed by heartbreak; Benji must reach his goal weight without the support of his brother.

Alicia's relationship with her boyfriend, Tim, comes under the microscope; Pauline must beg her way back onto the program after quitting.

Erica's success on her weight-loss journey is derailed by heartbreak; Benji must reach his goal weight without the support of his brother.

Alicia's relationship with her boyfriend, Tim, comes under the microscope; Pauline must beg her way back onto the program after quitting.

Tammy faces a tough choice when her husband wants her back, but only if she moves away from Houston and Dr. Now's program; Karina's weight loss begins to slow, but she finds happiness dating a guy Dr. Now is surprised to see in his clinic again.

Alicia, all smiles and laughter on the outside, secretly fears that her food addiction will kill her before she can marry her long-time love or watch her nieces grow up.

An overweight woman struggles with flesh-eating bacteria and butterfly shaped fat deposits; unexpected news threatens her weight loss journey.

Laura has used food to cope with her emotions; she is confined to a wheelchair and relies on an oxygen tank to breathe and her husband and mother to survive.

Unable to stand for more than a short period of time, Karina's weight places a burden on her parents and drives a wedge between her and her sister.

Lisa's struggle with her weight begins as a child and significantly worsens after witnessing her brother's murder; now bedridden and unable to care for herself, Lisa must find a way to lose the weight or she will never see her grandchildren grow up.

After years of a tumultuous relationship with her husband, Tamy's eating addiction has caused her weight to balloon to over 500 pounds; she has become a hermit and hopes to restart her life so she can better care for her son, Zachary.

Fearing he'll suffer the same fate as 700-pound brother David, Benji hopes to be able to support both himself and his brother on their life-or-death weight loss journey.

Former plus-size model and advocate Renee realizes the mortal mistakes she has made as her weight swells to 600 pounds and her health crumbles.

Jennifer and her daughter Marissa are stuck in a co-dependent relationship and, with a combined weight of over 900-lbs., both of their lives are in jeopardy; Jennifer must regain control and save both of their lives before it is too late.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

Jennifer and her daughter Marissa are stuck in a co-dependent relationship and, with a combined weight of over 900-lbs., both of their lives are in jeopardy; Jennifer must regain control and save both of their lives before it is too late.

Devastated by two miscarriages due to her weight, Schenee is desperate to start a family and stop relying on her husband, Freddie, to take care of her; she hopes weight loss surgery will be able to fix her fertility issues as well as her marriage.

Former plus-size model and advocate Renee realizes the mortal mistakes she has made as her weight swells to 600 pounds and her health crumbles.

A woman gets a Christmas tree imbedded in her neck; a boy out fishing almost chokes on a barb; a man is filled with enough air to fill 1000 balloons; learn how they survived.

A man gets a wire embedded in his heart; three year old swallows magnets; woman has pencil in her brain; man has a five centimeter splinter removed from eye.

A car accident leaves a pole penetrating a man's mouth and neck, a man accidentally eats a sewing needle, a 75-year-old man finds out he has had a nail in his face.

A couple's long awaited date night leads them to a secluded pasture; a couple with a hidden medical secret; an athletic couple loses their match against the "Kama Sutra."

A couple's alone time at a pool party gets them busted; a man looking to score medicine; a sticky situation that ends in the emergency room.

Alone time at a spa ends up like a crime scene; a nature lover's odd injury; a realtor and his crush go straight from the bedroom to the ER.

Stephen Dilbeck gets some shocking information about his birth family from Jane and Lisa; Chris and Sallie work on getting approval of an exhumation that will answer questions for hundreds of Hicks babies.

Jane and Lisa share the news about the exhumation with a group of Hicks babies that have questioned whether Dr. Hicks was in fact their biological father; Sallie and the Hicks babies learn the DNA results.

Wendy and her team encounter unexpected challenges with the exhumation; Sallie struggles emotionally with her decision to exhume; the Hicks babies learn the DNA results; three Hicks babies are connected with biological family.

Two sisters confront their Puerto Rican birth father after a lifetime of feeling abandoned; an adoptee turns her back on an upsetting past, as the new relationship with her biological mother flourishes.

Newly reunited sisters face a battle that strengthens their bond and uncover another secret held by their mother; two families explore the complicated relationship of sharing a son.

After hearing a shocking story from her biological mother, Kris seeks more answers about the disturbing truth behind her birth father; two strangers come forward with a potential connection to her story.

A surprisingly troubled outcome with her birth mother prompts an adoptee to find her father, leading to life-changing truths; a woman tries to repair relationships with the biological father she just met and the father who raised her.

After a joyful reunion with the daughter he was forced to give up, Jon now struggles to maintain their relationship; high school sweethearts who placed their son up for adoption happily meet his adoptive parents and participate in his wedding.

Ramon's keloids on the back of his head are so large that he may require a skin graft if removed; Lauren has a condition that gives her bumps inside and outside of her body; Tiana has an unknown condition, giving her what looks like four breasts.

Tiana hopes Dr. Mercy can figure out how to get rid of her two extra breasts; Michael wants his giant patches of skin tags removed for his 40th birthday; Chandra's lipoma is weighing her down physically and emotionally.

Dr. Mercy tries to remove Price's lipoma, which is so big that it has gotten in the way of his relationship; Ashley's case of neurofibromatosis is one of the worst in the country; Becca was born with a birthmark that covers the majority of her face.

Jorge's case of rhinophyma is so bad that he has a difficult time breathing; Tracy's body is covered in hundreds of lipomas; Cha comes to Dr. Mercy to help her gain her confidence back due to the bumps on her face.

Ramon's keloids on the back of his head are so large that he may require a skin graft if removed; Lauren has a condition that gives her bumps inside and outside of her body; Tiana has an unknown condition, giving her what looks like four breasts.

Tiana hopes Dr. Mercy can figure out how to get rid of her two extra breasts; Michael wants his giant patches of skin tags removed for his 40th birthday; Chandra's lipoma is weighing her down physically and emotionally.

Dr. Mercy tries to remove Price's lipoma, which is so big that it has gotten in the way of his relationship; Ashley's case of neurofibromatosis is one of the worst in the country; Becca was born with a birthmark that covers the majority of her face.

Jorge's case of rhinophyma is so bad that he has a difficult time breathing; Tracy's body is covered in hundreds of lipomas; Cha comes to Dr. Mercy to help her gain her confidence back due to the bumps on her face.

A surprisingly troubled outcome with her birth mother prompts an adoptee to find her father, leading to life-changing truths; a woman tries to repair relationships with the biological father she just met and the father who raised her.

After a joyful reunion with the daughter he was forced to give up, Jon now struggles to maintain their relationship; high school sweethearts who placed their son up for adoption happily meet his adoptive parents and participate in his wedding.

A patient fights for his life after a four-story fall; a 12-year-old boy is hit by a car and injures his foot.

A heart attack victim is brought back to life; a mother and her newborn survive a horrific crash; a 65-year-old man falls two floors down an elevator shaft.

A newborn with a potentially life-threatening infection; the victim of a gang-related attack; a patient who has survived a bullet passing through all of his vital organs.

A 16-year-old's behavioral issues may cause her to be expelled; daycare fees may force another student to leave school.

Florence's first prom; campaign to be prom queen.

A student struggles with self-esteem, weight issues and a son who has behavioral problems; a first time mom-to-be attempts to repair her relationship with her own mother.

Richanne is diagnosed with a brain tumor and pregnant; Paola's pregnancy could ruin her career.

Sandra relationship with her daughters; Dannielle risks her relationship with her grandfather.

Charity's sixth child is on the way; Natasha fears her boyfriend will leave her.

Amy's ninth child; Destiny is pregnant with twins at age 20.

The doctors and nurses of Good Samaritan Regional Medical Center pursue diverse goals at the Level One Trauma Center.

The staff at Rocky Mountain Regional Trauma Center in Denver treats victims of accidents, violence and illness.

Victims of car crash, scalding, burn.

Victims of shootings, stabbings, heroin overdose.

A teenage girl is impaled through the neck on an iron fence; a patient is convinced he's turning into a vampire; a first-year attending physician stands up to a room full of senior specialists to save the life of a critically ill pregnant woman.

The ER is a crime scene when a woman's belly pain is caused by smuggled narcotics; a doctor is mystified by heart attacks occurring the same day in the same family; strange markings on the body of a car crash victim lead to the cause of the accident.

Two seemingly unrelated gunshot wounds lead to a bizarre night in the ER; a senior nurse unravels at the sight of a critical patient, and reveals a shocking secret; a patient's grave symptoms mysteriously disappear whenever the doctor touches him.

A woman comes in with a piece of rebar impaling her thigh; a man brings his girlfriend into the ER for an STD workup; an ER doctor confronts a woman's prejudiced colleagues.

A teenage girl is impaled through the neck on an iron fence; a patient is convinced he's turning into a vampire; a first-year attending physician stands up to a room full of senior specialists to save the life of a critically ill pregnant woman.

The ER is a crime scene when a woman's belly pain is caused by smuggled narcotics; a doctor is mystified by heart attacks occurring the same day in the same family; strange markings on the body of a car crash victim lead to the cause of the accident.

Two seemingly unrelated gunshot wounds lead to a bizarre night in the ER; a senior nurse unravels at the sight of a critical patient, and reveals a shocking secret; a patient's grave symptoms mysteriously disappear whenever the doctor touches him.

A woman comes in with a piece of rebar impaling her thigh; a man brings his girlfriend into the ER for an STD workup; an ER doctor confronts a woman's prejudiced colleagues.

Victims of car crash, scalding, burn.

Victims of shootings, stabbings, heroin overdose.

Liz, completely bed-bound, has severe lymphedema that makes it impossible to walk; utterly isolated, Liz has no friends, battles depression and lives with a mother too ill to take care of her.

Bedridden Marla is so heavy she cannot stand up; she must face the hard truth about her condition and understand the toll it takes on her supportive family.

Chay has eaten his way to 600 pounds to cope with the emotional turmoil of his childhood; he loses his emotional support and searches for new strength to take control of his life.

After a difficult childhood with an abusive stepfather and drug-addicted mother, Sarah is fighting for her life at only 24 years old.

With the support of his fiancé, Kathryn, Robert turns to Dr. Nowzaradan in a final, desperate attempt to save his life; he tries to reverse a lifelong food addiction that has left him bed-bound, saddled with grotesque lymphedema, and nearly 900-lbs.

At over 700 pounds, Brianne undertakes a weight-loss journey to save her own life; she faces an unexpected challenge to her fragile progress when her husband suffers a heart attack on a birthday she will never forget.

Octavia has been bedbound for nearly a year when she decides to make the trip to Houston to get help from Dr. Now, but when it turns out that her best friend is also her worst enabler, Octavia will have to choose between old habits and a new life.

Robin and her brother Chris are both obese and already lost a sibling to obesity; they plan to visit Dr. Now together when Chris suffers a stroke and can't go; Chris' son Garrett, already 600 pounds at age 20, is game to join the journey.