A killer tried to destroy everything which could link them to the crime; but in doing so, they inadvertently created new forensic evidence, evidence which came to light using a technique never before used in a criminal investigation.

After a tycoon's wife is found dead in her SUV submerged in a half-frozen creek, police begin to suspect it wasn't an accident.

A Russian immigrant is found dead and a strange phone call to his office is the only lead investigators have.

Physical evidence intially condemns a prime suspect to a double homicide, but DNA from a discarded spoon points to another.

A young girl falls ill and dies; forensic investigators search for evidence halfway around the world to shed light on the tragic death.

Two bodies are discovered, shot to death in their car; the car windows are broken, but there's no sign of shattered glass.

Key suspect has a solid alibi in the murder of a war veteran; but police get a lead by finding a new suspect with a sweet tooth.

A woman who appeared to have taken her own life told her sister that, if anything were to happen to her, there was a note in the china cabinet.

When an aspiring model turns up dead, police suspect her boyfriend. But must dig deeper for clues when he is cleared.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

Melanie Zanona; Catherine Lucey; Isaac Arnsdorf.

Mike Williams mysteriously disappears on his wedding anniversary, and it looks like he may have been eaten by alligators, but looks can be deceiving; a break in the case reveals secrets.

Colorado soccer mom Paige Birgfeld vanishes and a small town is left on edge; cops dig for clues and make a shocking discovery that this devoted mom is living a secret double life.

Churchgoers know something is up when pastor Matthew Winkler doesn't show up for services: he's found dead on his bedroom floor and twisted sex fantasies and dark family secrets start to surface.

A successful lawyer, Mormon family man, and father of five is shot down in cold blood at a Walgreens parking lot, but a closer look reveals a dirty office affair that turned into a dangerous game of Russian roulette.

Tattoo shop owner Dennis Abrahamsen is found brutally murdered and naked on a massage table in his home; evidence tells a story of a wild sex party gone wrong with a famous adult actress.

Tiny fibers and an asthma inhaler are the clues that lead officers to the killer of an off-duty policeman.

Investigators search the world of high rollers and offshore betting to solve the first triple homicide in Verona, Wisc.

Police search every apartment building in town when the body of a young girl found on an isolated farm holds a set of keys but no ID.

A man denies killing a pedestrian in hit-and-run, claiming he sold the car in question, and authorities track down the car to find critical evidence.

Three years later, a second autopsy determines who's right when a medical examiner and detectives disagree on the cause of death.

Hit-and-run boating accident that kills a popular young man causes investigators to search for one boat out of thousands.

A woman is found dead on her bedroom floor, the only clue is a bloodstained sheet; breakthrough forensics enable police to identify the killer.

A young man is killed in a mysterious car crash, but the evidence at the scene lead investigators to believe it is not an accident; forensic science reveals what really happens, and the truth devastates three families.

A woman is found dead, police use blood evidence and computer forensics to convince a jury that the murderer is guilty.

When an elderly woman dies in an apparent robbery-homicide, evidence suggests the suspect broke out of the house rather than breaking in.

Wealthy man is shot dead while his wife is forced to open their hidden safe, but they couldn't be identified because they were wearing ski masks.

The bomb was constructed to cause as much damage as possible and it did, killing the victim with deadly force and flame; a painstaking search yielded tiny clues, which identified the killer as surely as if he'd signed them.

A twelve-year-old girl claims that she was abducted and sexually assaulted; her story seems unbelievable until police discover fibers on her clothing.

A man calls for help when his wife has a fatal fall down the stairs; numerous amount of bloodstains make police suspicious.

A decade old case reopens, and a few seconds of a 911 call enable investigators to determine who is responsible for a murder.

A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

A mussel diver and his fiancée are found dead in their burnt home; a tiny clue points to arson and murder.

For ten years, the disappearance of a college co-ed remained a mystery; new scientific testing cast a different light on a man who had been a suspect all along.

Three years later, a second autopsy determines who's right when a medical examiner and detectives disagree on the cause of death.

Hit-and-run boating accident that kills a popular young man causes investigators to search for one boat out of thousands.

A woman is found dead on her bedroom floor, the only clue is a bloodstained sheet; breakthrough forensics enable police to identify the killer.

A young man is killed in a mysterious car crash, but the evidence at the scene lead investigators to believe it is not an accident; forensic science reveals what really happens, and the truth devastates three families.

A woman is found dead, police use blood evidence and computer forensics to convince a jury that the murderer is guilty.

When an elderly woman dies in an apparent robbery-homicide, evidence suggests the suspect broke out of the house rather than breaking in.

Wealthy man is shot dead while his wife is forced to open their hidden safe, but they couldn't be identified because they were wearing ski masks.

The bomb was constructed to cause as much damage as possible and it did, killing the victim with deadly force and flame; a painstaking search yielded tiny clues, which identified the killer as surely as if he'd signed them.

A twelve-year-old girl claims that she was abducted and sexually assaulted; her story seems unbelievable until police discover fibers on her clothing.

A man calls for help when his wife has a fatal fall down the stairs; numerous amount of bloodstains make police suspicious.

A decade old case reopens, and a few seconds of a 911 call enable investigators to determine who is responsible for a murder.

A flawed envelope is an unlikely clue to identifying a killer who laced a water cooler with cyanide and caused the death of a woman.

A mussel diver and his fiancée are found dead in their burnt home; a tiny clue points to arson and murder.

For ten years, the disappearance of a college co-ed remained a mystery; new scientific testing cast a different light on a man who had been a suspect all along.

When the 20-year-old clerk of an Atlanta-area smoke shop is gunned down during a robbery, investigators have only descriptions of the killers and the make of their getaway car; investigators use a videotaped confession to smoke out the killers.

California police are baffled when an innocent man's DNA is found at the scene of a deadly home invasion, and authorities team with the man's defense attorney.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

From 1976 to 1977, David Berkowitz terrorizes New York City under his creepy self-given moniker: the "Son of Sam"; he is among the most infamous serial killers in American history.

In 1977, the city of New York is stalked by a seemingly faceless serial killer known as "Son of Sam"; after his final shooting takes him to Brooklyn, a twist of fate and a little luck leads to his capture.

He calls himself "B.T.K." which stands for "Bind, Torture, Kill" and for decades this bloodthirsty serial killer terrifies Wichita as he murders again.

For years the BTK killer plays a cat and mouse game with law enforcement and the media taunting them as he seeks the attention he craves.

Tipster is found dead after revealing that a woman's death 16 years ago was murder.

The murder of 53-year-old Paul Gruber is examined and the evidence points to Darryl Robin Kuehl, who was later convicted of the crime.

A man states that a robber shot and killed his wife while they were on the beach, but a song he downloaded makes investigators suspicious.

Detectives discover new clues left by a stalker's letter to his victim.

A killer is careless when using a murder weapon that is unique and easily traceable.

When a high school athlete is killed in a hit and run accident, investigators hoped tiny paint chips and shards of plastic would lead them to the driver.

A woman is abducted and a month later found dead, then a tip leads investigators in the right direction.

How the bombs were made leads investigators in Colorado to find the perpetrator.

DNA profiling reveals clues leading to a killer's identity 20 years later.

A device intended to save lives proves to be the only witness to a mans death.

When a man dies after falling down the stairs, a witness says one thing and the evidence says another.

A wax bullet, white blanket and olive colored carpeting, tell a lot about the murder of a young woman found in a ravine.

When a house burns to the ground and a woman's charred remains are found, investigators must determine whether it was an accident or arson.

An ammunition box and fluorescent fibers reveal the betrayal that led to the murder of a millionaire's family.

The 1960 kidnapping and murder of brewery heir Adolph Coors III leads to one of the most intense manhunts in U.S. history.

A used tissue, 12 years after the murder of a young Missouri woman, may be what cracks the case with a suspect list a mile long.

When murder strikes a young girl, police quickly make an arrest, but cutting-edge technology from NASA proves they have the wrong suspect behind bars.

A man is found strangled and burned in his San Antonio apartment and the killer thinks he has destroyed all the evidence.

A killer is careless when using a murder weapon that is unique and easily traceable.

When a high school athlete is killed in a hit and run accident, investigators hoped tiny paint chips and shards of plastic would lead them to the driver.

A woman is abducted and a month later found dead, then a tip leads investigators in the right direction.

How the bombs were made leads investigators in Colorado to find the perpetrator.

DNA profiling reveals clues leading to a killer's identity 20 years later.

A device intended to save lives proves to be the only witness to a mans death.

When a man dies after falling down the stairs, a witness says one thing and the evidence says another.

A wax bullet, white blanket and olive colored carpeting, tell a lot about the murder of a young woman found in a ravine.

When a house burns to the ground and a woman's charred remains are found, investigators must determine whether it was an accident or arson.

An ammunition box and fluorescent fibers reveal the betrayal that led to the murder of a millionaire's family.

The 1960 kidnapping and murder of brewery heir Adolph Coors III leads to one of the most intense manhunts in U.S. history.

A used tissue, 12 years after the murder of a young Missouri woman, may be what cracks the case with a suspect list a mile long.

When murder strikes a young girl, police quickly make an arrest, but cutting-edge technology from NASA proves they have the wrong suspect behind bars.

A man is found strangled and burned in his San Antonio apartment and the killer thinks he has destroyed all the evidence.

A young mother is found murdered in her home and there are two suspects with ample motive, but an unusual interview and security camera footage have investigators puzzled.

A fire leads investigators to reexamine an unusual death.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

In 2003, the wildly successful careers of master illusionists Siegfried and Roy comes to a shockingly abrupt end when one of the team's prized tigers bites Roy Horn on the neck and drags him off stage.

Roy tries to recover from severe wounds inflicted by his beloved tiger Mantacore; but excuses for the animal's behavior lose credibility.

On April 15th 2013, two bombs explode during the Boston Marathon, killing three spectators and injuring hundreds others.

With the Boston Bombing suspects identified as domestic terrorist brothers, the manhunt begins, and a terrifying crime spree ensues.

When two men appear to die of heart disease six years apart, police notice they have one thing in common, they were each married to the same woman.

Casino security cameras offer the final images of a woman, just before she vanishes without a trace; can these grainy images lead police to her killer?

A squashed tomato and a pinpoint reflection of light in a photo help catch a killer.

An ATM transaction allows Texas detectives to pinpoint a suspect in the slaying of a teacher, but a shoelace stolen from the victim's home proves to be the tie that binds her killer to the crime.

Ten years after the murder of a rock singer, forensic scientists use evidence collected to finally bring her killer to justice.

After a Michigan State University grad student disappears and is presumed dead, a professor of geological sciences helps police get the dirt on her killer.

When a man's wife kills herself 14 years after his college sweetheart commits suicide, police start to get suspicious.

A woman gets shot in her driveway; she may have been the victim of a co-worker half her age that she had recently rejected.

A pair of tennis shoes are found near a victim who had been stabbed on the beach, less than ten yards from her hotel.

Three fingerprints on a window screen are enough for a print examiner to uncover the work of a serial killer.

With a long list of suspects, forensic experts agree on one thing in this brutal murder: the killer knew his victim.

The only lead to finding a serial killer on the loose is a bloody fingerprint on the body of a victim.

Tests reveal the race, eye color and hair color of the person responsible for killing two young women on Halloween night.

A convicted arsonist claims his innocence and with no lawyer, no money and only a fifth-grade education, sets out to prove it.

A canine behaviorist uses the family dogs, who are the only witnesses, to find the murderer of their owner.

Investigators see through a killer trying to cover his tracks by staging the crime scene to learn what really happened.

A young girl beaten after watching her grandmother killed, identifies the wrong person; years later she tries to change her statement.

In 1984 police failed to convict the murderer of a college student; new technology may finally help the police to catch her killer.

Ten years after the murder of a rock singer, forensic scientists use evidence collected to finally bring her killer to justice.

After a Michigan State University grad student disappears and is presumed dead, a professor of geological sciences helps police get the dirt on her killer.

When a man's wife kills herself 14 years after his college sweetheart commits suicide, police start to get suspicious.

A woman gets shot in her driveway; she may have been the victim of a co-worker half her age that she had recently rejected.

A pair of tennis shoes are found near a victim who had been stabbed on the beach, less than ten yards from her hotel.

Three fingerprints on a window screen are enough for a print examiner to uncover the work of a serial killer.

With a long list of suspects, forensic experts agree on one thing in this brutal murder: the killer knew his victim.

The only lead to finding a serial killer on the loose is a bloody fingerprint on the body of a victim.

Tests reveal the race, eye color and hair color of the person responsible for killing two young women on Halloween night.

A convicted arsonist claims his innocence and with no lawyer, no money and only a fifth-grade education, sets out to prove it.

A canine behaviorist uses the family dogs, who are the only witnesses, to find the murderer of their owner.

Investigators see through a killer trying to cover his tracks by staging the crime scene to learn what really happened.

A young girl beaten after watching her grandmother killed, identifies the wrong person; years later she tries to change her statement.

In 1984 police failed to convict the murderer of a college student; new technology may finally help the police to catch her killer.

A young woman's naked body is discovered in a remote area leading forensic investigators on a search for clues to her identity and the identity of her killer.

When a Yale student mysteriously vanishes days before her wedding, investigators comb a secure research lab for clues.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Todd Kohlhepp's double life is exposed after police rescue a young woman chained like a dog inside a shipping container on his property.

A registered sex offender lures Cherish Perrywinkle, 8, away from a Walmart, and that's just the beginning of a night of terror, all caught on camera.

Fitness instructor Missy Bevers is stabbed and bludgeoned to death while setting up for an early-morning workout class at the local church; surveillance cameras capture a series of images of her killer lurking in the hallways.

Model Tara Lambert hires a hit man to kill her husband's ex-wife and put her in a wood chipper, but she doesn't know that cameras are rolling.

Police investigate a young woman found murdered two weeks after reporting a road rage incident; evidence leads not to the aggressive driver, but one of their own.

When a single mother is murdered, her brother vows to find the person responsible for the death of his sister, even if it takes more than 30 years.

A husband and wife get shot and their 16-year-old daughter manages to escape, but investigators suspect she may be involved in the murder.

After 10 years, a witness decides to do the right thing about the rape and murder of a young hairdresser.

Police investigate the possibility of a hate crime when two women go missing and are later found murdered.

When a human skeleton is found on marshland and determined to be at least 18 months old, a computer consultant gives her a face and name.

A killer places all the incriminating evidence to the murder in a plastic bag, hoping it will float down the river.

A woman's body is found inside a burned mobile home and the autopsy reveals she was beaten, making this a murder.

Security guard who disappeared from his post was found a year later in a remote camp site; a decade later, a phone call and a paint smear on his boot helped scientists determine what happened during his final moments.

When three students are brutally murdered close to campus, investigators must determine what the women had in common before their serial killer strikes again.

A bag full of evidence recovered from an iced-over river helps to reveal the murderer of a businesswoman in her own shop.

Eyewitness to real estate agent's murder is put under forensic hypnosis in an attempt to help him recall the killer's face.

Police launch a search for a killer after a teenager returns home to find his father's body in a pool of blood.

Pathologist examining the death of a politician who was running for re-election finds tiny puncture wounds at the autopsy.

A Naval officer who threatened to go public with tales of on-the-job sexual harassment and assault is brutally murdered, but when investigators find the allegations could be part of an elaborate scheme for money, they turn to forensic science.

A man is found stabbed to death after a night in a strip club; a drop of blood on a bedspread becomes critical evidence five years later.

After police identify a murder victim thanks to her butterfly necklace, they discover several co-workers had vendettas against the victim.

The brutal murder of a construction site foreman looks like the work of a disgruntled employee, but forensic science points to an unlikely suspect.

Police investigate the possibility of a hate crime when two women go missing and are later found murdered.

When a human skeleton is found on marshland and determined to be at least 18 months old, a computer consultant gives her a face and name.

A killer places all the incriminating evidence to the murder in a plastic bag, hoping it will float down the river.

A woman's body is found inside a burned mobile home and the autopsy reveals she was beaten, making this a murder.

Security guard who disappeared from his post was found a year later in a remote camp site; a decade later, a phone call and a paint smear on his boot helped scientists determine what happened during his final moments.

When three students are brutally murdered close to campus, investigators must determine what the women had in common before their serial killer strikes again.

A bag full of evidence recovered from an iced-over river helps to reveal the murderer of a businesswoman in her own shop.

Eyewitness to real estate agent's murder is put under forensic hypnosis in an attempt to help him recall the killer's face.

Police launch a search for a killer after a teenager returns home to find his father's body in a pool of blood.

Pathologist examining the death of a politician who was running for re-election finds tiny puncture wounds at the autopsy.

A Naval officer who threatened to go public with tales of on-the-job sexual harassment and assault is brutally murdered, but when investigators find the allegations could be part of an elaborate scheme for money, they turn to forensic science.

A man is found stabbed to death after a night in a strip club; a drop of blood on a bedspread becomes critical evidence five years later.

After police identify a murder victim thanks to her butterfly necklace, they discover several co-workers had vendettas against the victim.

The brutal murder of a construction site foreman looks like the work of a disgruntled employee, but forensic science points to an unlikely suspect.

A suitcase leads to the gruesome discovery of a nearly perfect crime.

A popular handyman in a New Hampshire town is found murdered and investigators follow forensic clues to a shocking conclusion.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

In 1993, James Raymond Jordan Sr. goes missing and his luxury car is found stripped and abandoned in North Carolina; clues point to a tragic crime.

Susan Powell, a twenty-eight-year-old mother of two, goes missing in December of 2009; more details about Susan's marriage to Josh and their life behind closed doors emerge.

Authorities search for missing mother of two, Susan Powell, in every nook and cranny of the desert in Western Utah while her friends and family wait for a break in the case.

Glenn Frey was a multi-talented musician and along with Don Henley, co-founded the legendary band, the Eagles; when Glenn Frey died in 2016 his fans were shocked.

A shooting victim mutters the name of her apparent assailant before dying, but fingerprint comparisons, handwriting analysis, ballistics and DNA testing show someone else close to home is the true killer.

A woman's story seemed far fetched; she tells investigators that a man broke into her home wearing only underwear and gloves, killed her boyfriend and raped and terrorized her.

After a Delaware man's mother is found dead, he tells a story that's so improbable police think it can't possibly be true.

A family vacation turns into a terrifying search for a missing wife and baby, then becomes a manhunt for a killer who committed a horrific crime.

A DNA dragnet catches a killer eight years after the kidnapping, rape and murder of a college coed in Oklahoma.

A nosy neighbor with a disturbing obsession becomes a suspect in a woman's murder at an upscale apartment complex; police discover an incredible link to an unrelated murder thousands of miles away.

A college student turns up dead and her boyfriend becomes a prime suspect when blood splatters are discovered on his wall.

Texas police hunt frantically for a brutal rapist. No one knows where he'll strike next, but given the increasingly violent nature of his crimes, he must be found soon.

When detectives find a mismatched button in relation to a woman's death, they know they can follow the clue back to the killer.

A woman heads home after church, but never makes it there alive, triggering a homicide investigation.

Volunteers and police spend weeks searching for a missing girl. A psychic later leads them to a field where the body was found.

Forensic investigators try to stop a killer who is apparently responsible for two slayings in a community in South Carolina.

When DNA proves that a man who practically admits to a brutal attack is innocent, police wonder why he is willing to take the blame.

When a businessman is murdered, motives and suspects are plentiful. Was it simply a disgruntled employee or client? Or do some racy photos hold the clue to the crime?

A family break turns into a nightmare when the wife is found face-down in a lake; with no idea whether it was murder, an accident or suicide, police turn to a new forensic technique.

When friends see a woman in the back of a car flailing her arms and screaming, they assume she is having fun, but when they later come upon a jacket and a pool of blood, they realize they witnessed an abduction in progress.

An attack on a couple's home leaves the husband dead, the wife gravely injured and their son as a prime suspect; hundreds of miles away, a DNA sample may lead to the killer.

Detectives think they've solved a murder when they find the weapon and victim's blood in a man's flat, but the evidence may have been planted.

A DNA dragnet catches a killer eight years after the kidnapping, rape and murder of a college coed in Oklahoma.

A nosy neighbor with a disturbing obsession becomes a suspect in a woman's murder at an upscale apartment complex; police discover an incredible link to an unrelated murder thousands of miles away.

A college student turns up dead and her boyfriend becomes a prime suspect when blood splatters are discovered on his wall.

Texas police hunt frantically for a brutal rapist. No one knows where he'll strike next, but given the increasingly violent nature of his crimes, he must be found soon.

When detectives find a mismatched button in relation to a woman's death, they know they can follow the clue back to the killer.

A woman heads home after church, but never makes it there alive, triggering a homicide investigation.

Volunteers and police spend weeks searching for a missing girl. A psychic later leads them to a field where the body was found.

Forensic investigators try to stop a killer who is apparently responsible for two slayings in a community in South Carolina.

When DNA proves that a man who practically admits to a brutal attack is innocent, police wonder why he is willing to take the blame.

When a businessman is murdered, motives and suspects are plentiful. Was it simply a disgruntled employee or client? Or do some racy photos hold the clue to the crime?

A family break turns into a nightmare when the wife is found face-down in a lake; with no idea whether it was murder, an accident or suicide, police turn to a new forensic technique.

When friends see a woman in the back of a car flailing her arms and screaming, they assume she is having fun, but when they later come upon a jacket and a pool of blood, they realize they witnessed an abduction in progress.

An attack on a couple's home leaves the husband dead, the wife gravely injured and their son as a prime suspect; hundreds of miles away, a DNA sample may lead to the killer.

Detectives think they've solved a murder when they find the weapon and victim's blood in a man's flat, but the evidence may have been planted.

A young mother is murdered in a crowded parking lot in broad daylight.

A serial killer terrorizes a small Texas town.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

A mysterious murder in an upscale community is solved by cell phone forensics.

After the brutal slaying of a young couple on a road trip, the victims' families begin receiving disturbing letters.

After a young mother is found brutally murdered in her home, investigators find startling clues on her cell phone that could lead to her killer.

An amazing new forensic tool turns a cold case around.

A gruesome find in a small town church sends investigators searching for a killer.

An insurance agent is shot execution style in his office, but the killer leaves no fingerprints, and there are no murder weapon found at the scene; then investigators discover a critical clue invisible to the naked eye that cracks the case.

A healthy, young mother mysteriously dies after a minor traffic accident triggering an investigation.

Investigators search for clues after a body is discovered in a watery grave.

Detectives search for the bombers of two churches in Illinois, hoping that the materials used in the remnants of the handmade bombs will offer the clues to catch the culprits.

There was no apparent reason for the young, healthy college student to be dead; but when the medical examiner found the tiniest of clues during the autopsy, investigators were able to unravel the mystery of betrayal and revenge.

A woman is stabbed a hundred times and her body positioned in a suggestive manner. This could be a hate crime against women.

Police are able to create a composite sketch of a man burnt beyond recognition. But tracking the killer is more challenging.

By cutting a strand of a murdered man's hair into sections, forensics reveal a record of his last six months alive, and find he was frequently ingesting huge amounts of arsenic.

A bullet-riddled car, a missing driver, and no witnesses, an ambush or a random attack; the clue was something so tiny, it was measured in millionths of a meter.

Teenager is found half-naked with her throat slit; a single foreign hair found on her thumb may finger the killer.

Two women who lived in the same apartment complex were brutally murdered; the similarities of the crime scenes led police to believe they were dealing with a serial killer who hated women, and they had to find him before he struck again.

Weeks after a student vanishes, the body of an unknown female is found in the ashes of a fire 700 miles away; an alert policeman realizes the crimes could be connected.

Investigators face a growing list of suspects after a beautiful flight attendant is brutally murdered in her own home.

The assistant manager of the restaurant had been stabbed to death; police knew why he'd been killed: $8,000 was missing from the safe. As to who was responsible, his family and friends couldn't even imagine who'd want to hurt him.

Florida authorities rely on DNA evidence to try to nail the killer of a woman who was abducted from her late-night job at a convenience store, raped and strangled.

A wild fire in a secluded parking lot leads police to discover a dreadful homicide, with the suspect's image caught by security cameras.

After a prominent Arizona surgeon is found stabbed to death outside his office, investigators uncover an unlikely suspect with deep pockets and an even deeper hatred for the doctor.

Police don't have a basis for comparison to match shoe impressions, blood drops and DNA evidence from a murder scene.

A masked gunman kills two members of a family and wounds two others after they interrupt his burglary at their upscale suburban home.

A killer leaves equally incriminating evidence at the scene when he meticulously wipes away his fingerprint and shoe impressions.

After a woman is found dead at a yacht club in California in an apparent case of love gone wrong, investigators discover her home life was as dramatic as films made in nearby Hollywood.

By cutting a strand of a murdered man's hair into sections, forensics reveal a record of his last six months alive, and find he was frequently ingesting huge amounts of arsenic.

A bullet-riddled car, a missing driver, and no witnesses, an ambush or a random attack; the clue was something so tiny, it was measured in millionths of a meter.

Teenager is found half-naked with her throat slit; a single foreign hair found on her thumb may finger the killer.

Two women who lived in the same apartment complex were brutally murdered; the similarities of the crime scenes led police to believe they were dealing with a serial killer who hated women, and they had to find him before he struck again.

Weeks after a student vanishes, the body of an unknown female is found in the ashes of a fire 700 miles away; an alert policeman realizes the crimes could be connected.

Investigators face a growing list of suspects after a beautiful flight attendant is brutally murdered in her own home.

The assistant manager of the restaurant had been stabbed to death; police knew why he'd been killed: $8,000 was missing from the safe. As to who was responsible, his family and friends couldn't even imagine who'd want to hurt him.

Florida authorities rely on DNA evidence to try to nail the killer of a woman who was abducted from her late-night job at a convenience store, raped and strangled.

A wild fire in a secluded parking lot leads police to discover a dreadful homicide, with the suspect's image caught by security cameras.

After a prominent Arizona surgeon is found stabbed to death outside his office, investigators uncover an unlikely suspect with deep pockets and an even deeper hatred for the doctor.

Police don't have a basis for comparison to match shoe impressions, blood drops and DNA evidence from a murder scene.

A masked gunman kills two members of a family and wounds two others after they interrupt his burglary at their upscale suburban home.

A killer leaves equally incriminating evidence at the scene when he meticulously wipes away his fingerprint and shoe impressions.

After a woman is found dead at a yacht club in California in an apparent case of love gone wrong, investigators discover her home life was as dramatic as films made in nearby Hollywood.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

The summer of 1985 was one of the hottest Los Angeles had seen in a century. But terrified residents weren't sleeping with the windows open; a killer known as the "Night Stalker" was on the loose.

A tip from a teenage boy leads to the identity of the Night Stalker and twenty-four hours later a mob of angry citizens track him down and capture him.

Desperate for answers community members live in terror waiting for the man dubbed the Co-Ed Killer to strike again.

In April 1973, Edmund Kemper, 24, murders six coeds in and around the city of Santa Cruz, Calif., shaking the community to its core.

The story of the millionaire heir to a vast real estate fortune who has been linked to the deaths of his wife, his best friend, and his neighbor.

Six weeks after jumping bail in Galveston, Texas, Robert Durst is caught on a store security camera in Pennsylvania shoplifting a sandwich and is quickly sent back to Galveston to stand trial for the murder of his neighbor, Morris Black.

The brutal murder of a state park employee over $2,000 rattles her co-workers and tourists while leaving police to sift through hundreds of leads.

When evidence shows a woman's rape and murder, police must find the killer as well as the victim.

A week after a couple disappears from the beach, police get a mysterious lead from a robbery.

Fifteen years later, DNA technology leads to justice for a murdered woman and her savagely beaten 4-year-old daughter.

A quiet waitress who hasn't been to work in two days vanishes without a trace; police suspect a date gone wrong.

The search for a missing exotic dancer led police to an isolated 75-acre site where someone had been shot and cremated, thus destroying all evidence... almost; piece of a foot provided enough DNA for a genetic profile and positive ID.

After years of suffering domestic abuse, a young woman is found murdered in her bathtub; among numerous clues, a hamburger bun proves the most incriminating.

Evidence that includes threatening emails, a missing person and an abandoned truck lead police to a woman's suspected killer, but they don't have the victim's body.

A woman has an accidental fall down a flight of stairs and appears to have hit her head, but the lack of blood splatter and misplaced shoes lead police to believe the fall was staged.

A church member gets gunned down after leaving choir practice; although witnesses see little and not much evidence exists, investigators learn that she had been having affairs for years.

When a man perishes in a fire while working in his garage, his death is initially ruled an accident until a forensic odontologist changes the direction of the case.

Lack of evidence compels investigators to look beyond the obvious when a woman is beaten to death at her in-laws house.

A man is found dead of an apparent suicide. But soon after, information emerges which reveals a much more menacing scenario.

A dismembered body is dumped on the side of the New Jersey Turnpike and before police realize it, bodies are turning up between two states.

A young bride-to-be is gunned down in her own home. The attack is personal and as investigators start digging, they uncover the man she loved was living a lie.

Tara Munsey went missing after a work shift at a Virginia restaurant and it is unknown if she ran away or if she was the victim of foul play.

An Ohio woman and her two daughters go missing while vacationing in Florida; their corpeses are found floating in Tampa Bay with a hand-written note by one of the victims; putting it on five billboards helps them find the killer.

Four young adults are murdered in an affluent Texas neighborhood, with little evidence but two people walking by dressed in black.

A quiet waitress who hasn't been to work in two days vanishes without a trace; police suspect a date gone wrong.

The search for a missing exotic dancer led police to an isolated 75-acre site where someone had been shot and cremated, thus destroying all evidence... almost; piece of a foot provided enough DNA for a genetic profile and positive ID.

After years of suffering domestic abuse, a young woman is found murdered in her bathtub; among numerous clues, a hamburger bun proves the most incriminating.

Evidence that includes threatening emails, a missing person and an abandoned truck lead police to a woman's suspected killer, but they don't have the victim's body.

A woman has an accidental fall down a flight of stairs and appears to have hit her head, but the lack of blood splatter and misplaced shoes lead police to believe the fall was staged.

A church member gets gunned down after leaving choir practice; although witnesses see little and not much evidence exists, investigators learn that she had been having affairs for years.

When a man perishes in a fire while working in his garage, his death is initially ruled an accident until a forensic odontologist changes the direction of the case.

Lack of evidence compels investigators to look beyond the obvious when a woman is beaten to death at her in-laws house.

A man is found dead of an apparent suicide. But soon after, information emerges which reveals a much more menacing scenario.

A dismembered body is dumped on the side of the New Jersey Turnpike and before police realize it, bodies are turning up between two states.

A young bride-to-be is gunned down in her own home. The attack is personal and as investigators start digging, they uncover the man she loved was living a lie.

Tara Munsey went missing after a work shift at a Virginia restaurant and it is unknown if she ran away or if she was the victim of foul play.

An Ohio woman and her two daughters go missing while vacationing in Florida; their corpeses are found floating in Tampa Bay with a hand-written note by one of the victims; putting it on five billboards helps them find the killer.

Four young adults are murdered in an affluent Texas neighborhood, with little evidence but two people walking by dressed in black.

Stories from across the world and refreshing conversations with Audie Cornish.

Stories from across the world and refreshing conversations with Audie Cornish.

Melanie Zanona; Catherine Lucey; Isaac Arnsdorf.

Mother of two Crystal McDowell vanishes as Hurricane Harvey rocks Houston; surveillance video leads investigators to her twisted killer.

Former model, Samira Frasch, was living a life of extravagance until tragedy struck; the mother of two is found dead at the bottom of her swimming pool and both her children are missing from the home.

Aspiring cosmetologist Shannon Graves is found dismembered inside a padlocked freezer but when another woman is spotted driving her car and going into her apartment, detectives discover a chilling cover-up.

Successful doctor and mom of two, Teresa Sievers, is found bludgeoned to death in her kitchen after returning home from a family vacation.

A 41-year-old mother of three was brutally stabbed nearly 200 times in front of her two youngest children; investigators reveal a sick and twisted motive behind the deadly rampage, and her daughter who witnessed the attack speaks for the first time.

A young college student is found dead in her apartment and the autopsy rules the death a homicide by an unknown male suspect.

The killer removed the computer that links him to the murder of a woman and her soon-to-be ex-husband that he had met online.

A community is shocked when police discover a woman raped and murdered in broad daylight on a public trail.

A real estate developer is shot and his wife becomes the prime suspect, until the bullet is linked to a weapon reported missing 20 years ago.

A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.

A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.

Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.

A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.

The investigation into the disappearance of flight attendant Helle Crafts leads to the murder conviction of her pilot husband.

Scientists and detectives use DNA to solve a string of rapes and murders.

Police believe they have a serial rapist and murderer, but DNA testing and research leads to another arrest and conviction.

In 1976, 182 war veterans in Philadelphia become hospitalized with pneumonia-like symptoms and 29 die; the disease resurfaces every few years.

After a wealthy Southern physician gets murdered with a baseball bat, his wife and a handyman become convicted of the crime.

In 1971, John List disappears after murdering his mother, wife and three children; he eludes the law for years until an age-scaled sculpture of the suspect and a true-crime TV program helps lead to his arrest in 1989.

An 11-year-old boy comes down with a fever and diarrhea after eating an undercooked burger; when his condition worsens, his mother drives him to a hospital and doctors discover E. coli destroying his body.

Florida police search for a serial rapist and murderer who left small red fibers on each of his 10 victims.

When an English couple go missing, police suspect their son killed them and must rely on mud and blood samples found in the couple's two cars to find their bodies.

Experts attempt to discover the source of heavy fog on Highway I-75 in Tennessee, which caused a 99-car accident and 12 deaths.

A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.

A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.

Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.

A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.

The investigation into the disappearance of flight attendant Helle Crafts leads to the murder conviction of her pilot husband.

Scientists and detectives use DNA to solve a string of rapes and murders.

Police believe they have a serial rapist and murderer, but DNA testing and research leads to another arrest and conviction.

In 1976, 182 war veterans in Philadelphia become hospitalized with pneumonia-like symptoms and 29 die; the disease resurfaces every few years.

After a wealthy Southern physician gets murdered with a baseball bat, his wife and a handyman become convicted of the crime.

In 1971, John List disappears after murdering his mother, wife and three children; he eludes the law for years until an age-scaled sculpture of the suspect and a true-crime TV program helps lead to his arrest in 1989.

An 11-year-old boy comes down with a fever and diarrhea after eating an undercooked burger; when his condition worsens, his mother drives him to a hospital and doctors discover E. coli destroying his body.

Florida police search for a serial rapist and murderer who left small red fibers on each of his 10 victims.

When an English couple go missing, police suspect their son killed them and must rely on mud and blood samples found in the couple's two cars to find their bodies.

Experts attempt to discover the source of heavy fog on Highway I-75 in Tennessee, which caused a 99-car accident and 12 deaths.

The murder of teacher's aide leaves a hole in the heart of her small community; as rumors spread about suspects, the actual perpetrator slips further away.

Father and teacher are found hanging naked from a tree with the letters F-E-D on his chest; with barely any evidence to work with, investigators turn to these letters for answers.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

For nearly two decades, physician-turned-murderer Michael Swango leaves a trail of death and mayhem across two continents.

Dr. Michael Swango takes an oath to do no harm, but does just the opposite; suspicious illnesses and deaths follow the once-trusted physician-turned-killer from hospital to hospital for nearly two decades and across two continents.

After a 40-year manhunt, investigators finally unmask the man suspected of being California's most prolific serial killer.

Law enforcement personnel identify the Golden State Killer as being Joseph DeAngelo who was hiding in plain sight.

When a woman goes missing from her home, police focus on her husband when an airline luggage tag and luminol point to an affair and murder; footage from a TV crew and Coast Guard photographs lead investigators to the suspect's missing boat.

When a woman exhibits strange flu-like symptoms before dying, investigators discover someone added thallium to her soda; detectives initially suspect her husband, but the case takes a sinister turn.

When dozens of infants develop serious breathing problems in the Cleveland area, doctors and investigators search high and low for the cause.

A well-liked bank vice president collapses and dies after taking pain pills laced with cyanide; the search for a motive reveals a callous suspect who had murdered once before.

Evidence reveals a teacher who complained of being stalked and harassed by another teacher was scamming police.

A man kills two people with bombs in an effort to get investors off his back, but authorities catch onto him and he becomes sentenced to life with no chance of parole.

A man arrested for the sexual assault and attempted murder of a boy in a European country becomes linked to a murder in Zurich, Switzerland, through analysis of microorganisms.

Heavy rains and snow run-off carry manure into Milwaukee's water supply in 1993, leading to an epidemic of gastrointestinal illness affecting 400,000 people.

Autopsies reveal that a string of unexplained deaths in Omaha resulted from poison-induced liver disintegration.

In a series of murders near Sacramento, Calif., a killer gags and molests prostitutes, cuts their clothes in random patterns and cuts off their hair; microscopic evidence helps solve the case.

After the discovery of a skull in the forest near a boy scout camp, police use facial reconstruction to identify the body.

Investigators use obscure evidence to find the person responsible for killing justice officials with mail bombs in the South.

Forensic scientists provide authorities with evidence that a death deemed accidental 20 years ago was actually murder.

Detectives learn that a genetic disorder caused the deaths of a woman's children, resulting in an overturned conviction.

When a young woman goes missing on the way to the train station, investigators use a strand of hair and a bloody pillowcase to find a suspect.

Investigators reopen a case from 1984 involving the rape of a young Virginia woman when DNA testing refutes her identification of the rapist and calls everything into question, leading to the accused person's exoneration.

A speck of bicycle paint and a speck of nickel left over from a collision with a twice-convicted child molester's car provide critical clues in the murder of a 9-year-old.

A 2-year-old boy's brain seizures and breathing problems baffle doctors until they learn the mother exhibits signs of Munchausen syndrome by proxy, a rare condition that led her to physically abuse her son and contributed to her daughter's death.

Evidence reveals a teacher who complained of being stalked and harassed by another teacher was scamming police.

A man kills two people with bombs in an effort to get investors off his back, but authorities catch onto him and he becomes sentenced to life with no chance of parole.

A man arrested for the sexual assault and attempted murder of a boy in a European country becomes linked to a murder in Zurich, Switzerland, through analysis of microorganisms.

Heavy rains and snow run-off carry manure into Milwaukee's water supply in 1993, leading to an epidemic of gastrointestinal illness affecting 400,000 people.

Autopsies reveal that a string of unexplained deaths in Omaha resulted from poison-induced liver disintegration.

In a series of murders near Sacramento, Calif., a killer gags and molests prostitutes, cuts their clothes in random patterns and cuts off their hair; microscopic evidence helps solve the case.

After the discovery of a skull in the forest near a boy scout camp, police use facial reconstruction to identify the body.

Investigators use obscure evidence to find the person responsible for killing justice officials with mail bombs in the South.

Forensic scientists provide authorities with evidence that a death deemed accidental 20 years ago was actually murder.

Detectives learn that a genetic disorder caused the deaths of a woman's children, resulting in an overturned conviction.

When a young woman goes missing on the way to the train station, investigators use a strand of hair and a bloody pillowcase to find a suspect.

Investigators reopen a case from 1984 involving the rape of a young Virginia woman when DNA testing refutes her identification of the rapist and calls everything into question, leading to the accused person's exoneration.

A speck of bicycle paint and a speck of nickel left over from a collision with a twice-convicted child molester's car provide critical clues in the murder of a 9-year-old.

A 2-year-old boy's brain seizures and breathing problems baffle doctors until they learn the mother exhibits signs of Munchausen syndrome by proxy, a rare condition that led her to physically abuse her son and contributed to her daughter's death.

A single mom vanishes without a trace; foul play is confirmed after a truck toolbox opens with her body inside; homicide detectives investigate men she matched on dating sites, men from work, and a lover with a violent past.

A 20-year-old woman sets out on her bike and never returns; her body is found a few miles from her house with a gunshot wound to the head; years go by without any evidence or leads, until new investigators and technology breaks the case.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Two dangerous killers break out of prison; convicted murderers Richard Matt and David Sweat cut through steel walls and crawl through pipes to escape.

The manhunt for escaped prisoners Richard Matt and David Sweat expands from the United States to Canada; thousands of leads, but still no sign of the missing men.

Bernie Madoff was a legend on Wall Street but he would eventually confess to his sons that he had been living a lie, that this secret fund was nothing more than a multi-billion dollar fraud and the largest Ponzi scheme ever.

The news of Bernie Madoff's arrest sent shockwaves around the world; investigators unravel a scheme that went back decades and involved several loyal employees.

Two years after an 18-year-old's murder in Albion, Mich., a tiny drop of blood and burned bones lead police to her killers.

A mother claims that an intruder murdered her two sons, but lacking a motive, police use blood-spatter analysis and behavioral profiling to reconstruct a different scenario.

A routine missing persons report leads Texas police to discover a deadly love triangle; evidence found in a suspect's home matches the murder scene and leads to the indictment of the victim's girlfriend and her lover.

A 1995 fire razes the mansion of a Kansas doctor, killing two of her three children; disturbing accounts from an ex-husband lead investigators to believe the doctor set the blaze herself.

A husband confesses to his wife's murder, only to be found not guilty a year later when a phone tip and forensic evidence point to another.

In Lorton, Va., police attempt to determine who abducted 5-year-old Melissa Brannen after she disappears from a Christmas party, but cannot be certain until they match hair from a rabbit-fur jacket Brannen wore that day.

When a Pennsylvania man checks into a hospital for leg pain and later dies of thallium poisoning, police investigate his wife and find her in the process of collecting an insurance payment for her previous husband's death.

Police exhume the body of Karla Brown, murdered in her home in 1978, to study bite wounds, which eventually lead to the killer.

A new life-insurance policy sparks suspicions of murder when a Nova Scotia schoolteacher's body is found at the bottom of her basement stairs.

A beverage company pleads guilty to violating federal safety laws when a baby dies from E. coli after drinking apple juice.

A woman who survived a deadly childhood fire sends police a letter charging that her father killed her mother 30 years ago.

After more than 20 people on a Native American reservation die suddenly from a flu-like disease, Navajo medicine men provide a clue that leads to a most unlikely killer.