With bonus scenes; James has a large, squishy forehead lump; Tanisha has an arm growth and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison.

Sean's nightmare keeps coming true, he can't stop pooping himself on stage; Tired of dealing with explosive bowels, Sean asks Dr. Hodges for help; Latoya wants to spend time with her kids again which means the 10 pound mass between her legs needs to go.

AliceJean's botched lap band removal left her with six belly buttons that form a golf course on her stomach; Simone seeks help for her uncontrollable vomiting.

After a botched lap band surgery, Christina has been blending her meals for over a decade; Dr. Caplin assists a patient whose tummy tuck has left her with a butt crack for a stomach.

With bonus scenes; James has a large, squishy forehead lump; Tanisha has an arm growth and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison.

A man injured in a medieval role playing battle has a sword impaled in his head; a critically ill patient is so afraid of germs he won't allow doctors to treat him; two patients with the same life-threatening symptoms.

A doctor treats three gunshot victims who claim be innocent bystanders; a doctor must perform emergency brain surgery on his first day; a bride-to-be suddenly slips into a diabetic coma.

A number of challenges seem to have cornered Betti Jo and her husband; Susan encounters a serious problem that can throw everything off track.

Chuck's second year of weight loss and a new relationship; Paula struggles with juggling many responsibilities along with her weight-loss.

Penny returns to Maryland believing she can lose weight; Tara continues to lose weight and is dating for the first time.

Over 11 years, Melissa has lost 500 pounds and saw her weight drop to 137 pounds; now facing marital problems, three pregnancies, and life as a single mom, Melissa is struggling with a 150-pound weight gain and finds herself at a crossroads.

Steven Assanti weighs nearly 800 pounds and his brother Justin almost 600 pounds, and although they can't stand each other, their father packs up the family to travel across the country and seek help.

After successful sleeve gastrectomy procedures, the Dreier twins collectively lose more than 400 pounds and work toward skin surgeries when a major life event disrupts their world and threatens their progress.

Erica must return to California to continue her weight-loss journey, but she fears past emotional trauma will derail her progress.

Ashley lost over 200 lbs. in Houston, but a family of enablers threatens her progress; Diana has shed 300 lbs., but knee damage may cause her to regain weight.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Ashley hits an emotional wall and is desperate for skin surgery, but she's not losing any weight; after being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

Kirsten must gain independence to get a full gastric bypass; Michael struggles to lose and battles anger issues; Michael's wife, Roni, wants surgery too.

Ashley hits an emotional wall and is desperate for skin surgery, but she's not losing any weight; after being evicted, Nicole is forced to move back to Ohio, which could impact her weight loss journey.

Ashley lost over 200 lbs. in Houston, but a family of enablers threatens her progress; Diana has shed 300 lbs., but knee damage may cause her to regain weight.

When Nathan's weight gets in the way of his job as a drama teacher, it's a wake-up call for him; changing his life might mean a falling out with his wife, Amber, who is also overweight, unless she can lose, too.

Penny has been bedridden for four years and moves to Texas to have gastric bypass; her unwillingness to make lifestyle changes could mean failure.

Chuck weighs almost 700 pounds; he has had to downsize his business and his wife feels like a single-parent who is ready to leave him.

Lacey is so big from overeating that she can barely leave the house, but that hasn't stopped her from finding love with Ricky; Lacey's weight isn't the only thing between her and a happy husband, however, with Ricky's sister Sharon in the picture.

For Julian and his wife, Irma, it was love at first sight; in order to grow old together, Julian will have to overcome the food addiction that made him more than 800 pounds.

Bianca is all in for a move to Houston with her boyfriend and two young kids to get Dr. Now's help with a second weight-loss surgery.

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

Doctors treat a gunshot victim who has a life-threatening wound to the head.

Staff treats patient injured while engaging in risky behavior at night.

Medical staff treats a patient who was hit by a train while crossing the tracks.

Brittany lands in the ER after losing a sex toy in her rectum; Buddy sees Dr. Carothers when he gets a bug in his ear; a pre-teen is brought in to see Dr. Mellick after getting impaled by a massive splinter; Zion has an earring stuck in his ear.

A pregnant Kayla is rushed to the ER for abdominal pain, but Dr. Crawford finds something; an entire bike brake is embedded in Jasmine's thigh; Mary has a fingernail stuck in her ear; Destiny's mouth smells like decaying flesh.

Doctor Crawford needs to remove a barbed nail embedded deeply in the forearm of a patient; Doctor Mellick must meticulously extract an unexpected item from an eye.

A woman has a two-hour orgasm that won't stop; an unlikely spot to make love; a naked man's three-story fall.

A 440-pound virgin sends his girlfriend through a wall; a bandleader collapses in the middle of a peak performance; a broken penis.

A man breaks out in a rash after intimacy; a major injury in bed; a concussion.

A hot time in a hotel room; a couple attempts to have sex in a tree; a woman dislocates her jaw.

Jamie's tiredness leads to shocking news; David has joint pain and low stamina.

Bonnie's tingling foot; Shannon's high fever causes her to black out.

Jordan has bleeding gums and bruises; Tannis has headaches and high blood pressure.

Kurt's body lumps; Jessica's cheek numbness and dizziness.

Dr. Meegan Gruber specializes in performing surgery while patients are completely awake; Derrick orders lunch while getting his "man boobs" removed; Genny has a request to get rid of both of her chins; Megan needs surgery to fix her "ballsack arms."

Dr. Meegan Gruber faces the most daunting awake surgery of her career: removing a giant hanging stomach; Jason looks for a butt lift to help him scandalize all of Kentucky; a patient calls her psychic mid-surgery.

Mother of eight Rubi stuns Dr. Meegan Gruber when she arrives with a hip condition unlike anything the doctor has ever seen; Ashley asks to have her bat wings clipped; Jim seeks a solution for a giant neck that's swallowing his jawline.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two painful bumps on his neck and one on his finger; a former cruise ship worker hopes Dr. Lee can remove her large back growth.

Dr. Meegan Gruber specializes in performing surgery while patients are completely awake; Derrick orders lunch while getting his "man boobs" removed; Genny has a request to get rid of both of her chins; Megan needs surgery to fix her "ballsack arms."

Dr. Meegan Gruber faces the most daunting awake surgery of her career: removing a giant hanging stomach; Jason looks for a butt lift to help him scandalize all of Kentucky; a patient calls her psychic mid-surgery.

Mother of eight Rubi stuns Dr. Meegan Gruber when she arrives with a hip condition unlike anything the doctor has ever seen; Ashley asks to have her bat wings clipped; Jim seeks a solution for a giant neck that's swallowing his jawline.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two painful bumps on his neck and one on his finger; a former cruise ship worker hopes Dr. Lee can remove her large back growth.

Jordan has bleeding gums and bruises; Tannis has headaches and high blood pressure.

Kurt's body lumps; Jessica's cheek numbness and dizziness.

A single mother finds she can no longer walk.

A military wife suffers a sudden paralysis in her leg that defies explanation; doctors discover it may have something to do with her husband's top secret work.

When a young woman goes to the ER with severe abdominal pains, the doctors find a rare and virulent type of cancer that gives her ten years to live.

Doctors suspect a woman in pain of being neurotic.

Pregnant detainees await trial; Jamie, a mother of four struggles for visitation rights; Tanya requests house arrest to prepare for the birth of her son.

Latoya struggles with giving up her baby for adoption; Esther is sent to disciplinary segregation.

A former wild child's GED; a student wonders if she's Valedictorian.

A 16-year-old's behavioral issues may cause her to be expelled; daycare fees may force another student to leave school.

Florence's first prom; campaign to be prom queen.

A student struggles with self-esteem, weight issues and a son who has behavioral problems; a first time mom-to-be attempts to repair her relationship with her own mother.

A woman goes into delivery while in a cab; a life-threatening pregnancy; twin sisters have their babies on the same day.

A best friend's offer to be a surrogate results in a life-threatening pregnancy; a woman is bitten by a deadly snake three weeks before her due date; a cupcake famed for inducing labor.

A woman gives birth while trapped in an elevator; two truckers deliver a baby in a diner; a prolapsed umbilical cord threatens a baby's life.

A grandma-to-be acts as surrogate for her daughter's baby; a very premature baby arrives at a playground; a woman gives birth at home.

Lisa helps a man find answers about his adoption; a breast cancer survivor searches for her birth mother.

Chris unwraps the mystery of a woman's origins, which at a Korean orphanage; Lisa desperately searches for a woman's only child, hoping it will heal her.

Lisa hopes that locating a man's biological mother will finally allow him to overcome his lifelong struggle with abandonment; Chris locates a woman's only child and delivers the difficult details of her daughter's birth story.

Identical twins enlist Lisa's help to unlock the mystery of why they were placed for adoption; Chris hopes to fulfill the wishes of a deceased father by tracking down the first-born son he and his wife had placed for adoption.

Lisa helps a man find answers about his adoption; a breast cancer survivor searches for her birth mother.

Chris unwraps the mystery of a woman's origins, which at a Korean orphanage; Lisa desperately searches for a woman's only child, hoping it will heal her.

Lisa hopes that locating a man's biological mother will finally allow him to overcome his lifelong struggle with abandonment; Chris locates a woman's only child and delivers the difficult details of her daughter's birth story.

Identical twins enlist Lisa's help to unlock the mystery of why they were placed for adoption; Chris hopes to fulfill the wishes of a deceased father by tracking down the first-born son he and his wife had placed for adoption.

A woman gives birth while trapped in an elevator; two truckers deliver a baby in a diner; a prolapsed umbilical cord threatens a baby's life.

A grandma-to-be acts as surrogate for her daughter's baby; a very premature baby arrives at a playground; a woman gives birth at home.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

Amber is 23, over 600-lbs, and relies on her family and boyfriend for even simple needs; her fear of dying young is so overwhelming that she decides to relocate 2,000 miles in hopes that weight loss surgery will give her life back.

Susan, 37-year-old woman, has never lived on her own because of her weight, is finally seeking help to get out on her own.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Lisa wouldn't have made it this far without the help of her chief enabler, her boyfriend Randy; when Randy falls ill, Lisa finds out if she has the will and determination to turn her life around.

Growing up in foster care, David suffered from a lack of attention and didn't develop a sense of self-worth; now he's relying on his favorite foster mom to support him as he finds the motivation to change and save his own life.

Lacey ballooned up over 600 lbs on pizza and ice cream and knows Dr. Now is her best hope for success; she must now rally her divorced parents around her for support and find a way to modulate her moods that won't include binge-eating.

Brandon is a talented musician with a beautiful voice and a run-away weight problem; he wants to lose weight and embark on a career; he also wants to take the next step with his girlfriend, Taylor, whom he risks losing if he can't make a change.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Despite moving to Houston with the solid support of her boyfriend, Aaron, and her cousin, Jasmine, Tiffany finds it difficult to break the cycle of depressed eating when her two roommates don't join her diet and leave the house every day for work.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Despite moving to Houston with the solid support of her boyfriend, Aaron, and her cousin, Jasmine, Tiffany finds it difficult to break the cycle of depressed eating when her two roommates don't join her diet and leave the house every day for work.

Brandon is a talented musician with a beautiful voice and a run-away weight problem; he wants to lose weight and embark on a career; he also wants to take the next step with his girlfriend, Taylor, whom he risks losing if he can't make a change.

Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove.

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

Stacey's shoulder growth prevents her from being the playful teacher she once was; Matthew worries that his mysterious shin rash may be dangerous.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches. Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort. Sharon has an embarrassing, stinky, squirting cyst under her breast.

Keke is covered in bumps that make her embarrassed to be intimate with her husband; Jim is a widower with two lumps who wants them removed for himself and his late wife; Corey has been labeled a devil worshipper because of his forehead growth.

Monica returns for a second time in hopes that Dr. Lee can remove some more of her face growths; Ken has several large cysts on his head that he has tried to remove on his own; Maranda has a mystery skin sore that causes discomfort.

Corey is a drag queen and has a bump dangling from his booty; Adam has a semi-circle of about a dozen cysts on his head that he covers with a hat; Virginia has large growths on both of her upper arms that make it difficult to travel in her RV.

Terry's nose growth has prevented him from meeting his grandkids; Remi has alligator-like skin and is not used to taking care of herself; Austin has an embarrassing birthmark right next to his eyelid; Mary Jo has a throbbing bump on her neck.

Roger has enormous growths on his nose that drip pus, attract flies, and are so large that he can barely breathe; Sandra and Jessie are sisters who bonded over their many undiagnosed face bumps.

Roger returns with his gigantic nose growths in the hope that Dr. Lee and her colleagues can help before it's too late; Christine has lost her essence due to a large growth on her shoulder; Tiffany has a recurring cyst on her eyelid.

Gabriel has a huge growth on his clavicle but is terrified of surgery; Karen has dealt with painful, scaly feet for 22 years with no diagnosis; Lorne has embarrassing tumors on his face and body and believes this is why he hasn't met the one yet.

Ruben is a personal trainer whose head growth has prevented him from seeing clients; Kaitlin has blue marks and scars up and down her arms due to long-term drug use; Adrian was left with a disfiguring bump on her behind after falling down stairs.

Margarita is a matriarch who has been hiding her armpit lump from her family; Kayla is an aspiring musician with a promising career that her painful eczema has brought to a halt; Bradley has a concerning growth that looks like raw meat on his leg.

Jeremy is a pastor with a hanging growth in an embarrassing location; Evelyn has recurring keloids that have been removed three times and come back bigger each time; Todd has a bump protruding from his forehead.

Tameru is a drag queen, but he has a myriad of cysts that are the real drag; Devon has uneven skin she thinks may be the result of a hysterectomy a decade ago; Amy has large growths all over her head that make her look like a "hot mess."

Jason lost their confidence and motivation due to the large growth on his neck; Shawnell's multiple mystery bumps on her head destroy her self-esteem; Jim's growth protruding off of his nose makes it hard to breathe.

Roger has a growth on his shoulder that he calls his second head; Jenna is a teenager with a bubble behind her ear; Susan is covered in bumps that effect her everyday life.

Jeremy is a pastor with a hanging growth in an embarrassing location; Evelyn has recurring keloids that have been removed three times and come back bigger each time; Todd has a bump protruding from his forehead.

Tameru is a drag queen, but he has a myriad of cysts that are the real drag; Devon has uneven skin she thinks may be the result of a hysterectomy a decade ago; Amy has large growths all over her head that make her look like a "hot mess."

Jason lost their confidence and motivation due to the large growth on his neck; Shawnell's multiple mystery bumps on her head destroy her self-esteem; Jim's growth protruding off of his nose makes it hard to breathe.

Roger has a growth on his shoulder that he calls his second head; Jenna is a teenager with a bubble behind her ear; Susan is covered in bumps that effect her everyday life.

Ruben is a personal trainer whose head growth has prevented him from seeing clients; Kaitlin has blue marks and scars up and down her arms due to long-term drug use; Adrian was left with a disfiguring bump on her behind after falling down stairs.

Margarita is a matriarch who has been hiding her armpit lump from her family; Kayla is an aspiring musician with a promising career that her painful eczema has brought to a halt; Bradley has a concerning growth that looks like raw meat on his leg.

A man falls five stories; a shopkeeper is shot in the head at point-blank range; a woman accidentally drinks a bottle of cleaning fluid.

A man wounded in a drive-by shooting; a patient with flesh-eating bacteria; a woman hit by a car.

Two brothers arrive at the ER after being crushed by a falling building; a victim of a gang-related incident; a patient who fell 40 feet.

A woman cracks under the pressure of jail life; a woman who is pregnant finds herself in the middle of a jailhouse brawl; a heroin addict chooses to stay in jail.

A woman works through the fallout of her addiction; a woman involved in a drug cartel seeks redemption; a pregnant woman prays; a woman attempts to smuggle contraband.

A jail newcomer gets more than she bargains for; a young mother's release is postponed; the tenth trip for a heroin addict.

A crack-addicted pregnant prostitute finds safe haven in jail; two best friends share a heroin addiction; a prostitute struggles to overcome her past.

Krystal is keeping the baby a secret; Danie fears her dad will reject her baby.

Carmen is a struggling single mother; Jerline and her husband are unemployed.

Jen is pregnant again after a stillbirth; Chanda is afraid to tell her parents of her pregnancy.

Louisville's University Hospital sees the results of domestic violence.

The staff of Vanderbilt University Medical Center's emergency room deals with patients during the summer in Nashville, Tenn.

Staff at Houston's Memorial Hermann Emergency Trauma Department treat a teen hit by a truck, a child attacked by a dog and victims of a three-car pileup.

The staff at Alameda County Medical Center is forced to improvise techniques and treatments due to outdated equipment and supply shortages.

The bulbous tumor growing from Jennifer's stomach threatens her relationship with her long-time boyfriend; fifteen-year-old Marcelo travels from Angola to Los Angeles to have a massive neck tumor removed, but the operation may be too risky.

Charmaine from Trinidad suffers from one of the most extreme cases of neurofibromatosis ever recorded; tumors cover every inch of her body and obstruct her ability to breathe and swallow; without surgery, these growing tumors threaten her life.

Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist; as the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.

Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor; Amy has let the tumor on her back grow for more than 17 years; after finally making the decision to remove it, she learns that now it might be too late.

The bulbous tumor growing from Jennifer's stomach threatens her relationship with her long-time boyfriend; fifteen-year-old Marcelo travels from Angola to Los Angeles to have a massive neck tumor removed, but the operation may be too risky.

Charmaine from Trinidad suffers from one of the most extreme cases of neurofibromatosis ever recorded; tumors cover every inch of her body and obstruct her ability to breathe and swallow; without surgery, these growing tumors threaten her life.

Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist; as the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.

Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor; Amy has let the tumor on her back grow for more than 17 years; after finally making the decision to remove it, she learns that now it might be too late.

Staff at Houston's Memorial Hermann Emergency Trauma Department treat a teen hit by a truck, a child attacked by a dog and victims of a three-car pileup.

The staff at Alameda County Medical Center is forced to improvise techniques and treatments due to outdated equipment and supply shortages.

Back on Dr. Nowzaradan's program, James is suspected of cheating as he continues to gain weight and suffers a series of life-threatening illnesses; Cynthia continues to lose weight but seems satisfied to do so at her own pace.

Melissa, mother of four, finds herself feeling overwhelmed due to a rocky marriage and an unexpected pregnancy; when Ashley's weight-loss journey hits a wall, she sets out to find new inspiration to get herself back on track.

Christina's weight loss threatens her life; after losing 300 pounds, Paula must endure more surgery to deal with a body entirely covered in loose and sagging skin.

Brittani has lost over 400 pounds in two years, so she and husband Bill think about expanding their family; Lupe has struggled since surgery, but, having left her husband, may finally start to make the permanent changes she needs.

Sean must overcome recent tragedies in his life before he loses all the progress he made over the last two years; Dottie struggles to stay on track while maintaining her family life.

Milla is dependent on her children and seeks to lose enough weight to be able to walk; Charity is mired in a deep depression, while her daughter, Charly, battles a food addiction; they strive to turn things around and reach their goal weight.

Doug has lost over 200 pounds and is more involved with his family life. He is now an example of healthy habits, but eating disorders threaten to derail his progress.

Pauline's self-destructive behavior continues to be a problem; Chad strives to be a better father and husband as he continues his journey; June's progress stalls when frequent travel and wedding plans cause her to slip back into bad habits.

After a year on a weight loss program, Steven remains completely non-compliant and Justin focuses on a new career instead of his diet, but time is quickly running out for surgery; Kylie and Anna prepare for skin removal surgery.

A year since her weight-loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat her if she can't find a way to control her eating habit and start walking again.

After a year on a weight loss program, Steven remains completely non-compliant and Justin focuses on a new career instead of his diet, but time is quickly running out for surgery; Kylie and Anna prepare for skin removal surgery.

A year since her weight-loss journey began, Janine is still in the 500s and mostly immobile, and now, Dr. Nowzaradan is running out of options for how to treat her if she can't find a way to control her eating habit and start walking again.

Pauline's self-destructive behavior continues to be a problem; Chad strives to be a better father and husband as he continues his journey; June's progress stalls when frequent travel and wedding plans cause her to slip back into bad habits.

Lupe has spent the last 10 years in bed and is totally dependent on her husband, prompting a cross-country move that could save her life or end up backfiring.

Pauline is 51-years-old and nearly 700 pounds; her addiction to food has taken over the life of her son and primary caretaker.

At 24-years-old, Bettie Jo is on her way to reaching 700 pounds and relies on her husband for her basic needs.

Twins Kandi and Brandi have a combined weight of over 1,100 pounds and fear losing each other to obesity, so they decide to make a change together.

At 670 pounds, Ashley, who lives in her parents' home with her husband, decides she must make a drastic change to save her life and her marriage.

Erica regrets not keeping a promise to her mom and hopes her siblings will help, but they're reluctant based on her past failures.

Cynthia, a single mother focused on raising five kids, comes to realize what her death would mean for their future.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

Diana, a once thin and active woman, is now a prisoner to her body and trades the comfort of her apartment for a weight loss journey under the strict authority of her niece.

James becomes bedridden, unable to stand and can barely move his legs; Holly and Mark prepare for skin removal surgery.

Diana, a once thin and active woman, is now a prisoner to her body and trades the comfort of her apartment for a weight loss journey under the strict authority of her niece.

James becomes bedridden, unable to stand and can barely move his legs; Holly and Mark prepare for skin removal surgery.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

Constant respiratory infections and an inability to grow; mysterious spasms and back pain overcome a man's life.

Harry is born healthy but his body starts transforming; Sadie is on the brink of starvation.

A girl is born with shocking deformities; a college student suffers from fluid around his heart and lungs.

A successful businesswoman suddenly seems to become possessed by demons; a young college student battles monstrous pain when she grows fingernails out of her hair follicles.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.

A woman believes her neighbors want to kill her; a man is near death after an arrow pierces his chest; two women with swollen abdomens refuse to explain the cause of their pain.

A circus sword-swallower suffers from a persistent case of hiccups; a mother and daughter mysteriously collapse in the ER; a woman loses control of her legs at her daughter's graduation.

An ER doctor's friend arrives at the hospital combative and out of control; a cyclist's throat is torn open when a driver opens a car door in her path; a nursing student is found passed out on the hospital floor.

A young girl is mysteriously paralyzed from the waist down; a young man complains of a splitting headache; a bride-to-be has appendicitis on her wedding day.

Megan is a 33-year-old alcoholic with social anxiety and a troubled past.

Phil is a 58-year-old meth user whose addiction spans over three decades.

Theresa is a homeless alcoholic whose addiction puts her life at risk.

Heroin addicts that live in a tent.