Thederick has become housebound from eating and only goes outside to greet the ice cream man; after a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.

Cindy is resistant to change and spends years creating a world that makes her feel safe; when her friend notices Cindy's health declining rapidly due to her size, she pushes Cindy to move to Houston and see Dr. Now.

Twenty years after her father died as the result of a botched weight-loss surgery, Carrie is on the brink of eating herself to death; she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband, Chris.

The recent revelation of a 49-year-old man's adoption sends Chris searching for answers to a secret his adoptive parents took to the grave; a biracial woman enlists Lisa's help to find her birth family, revealing some unfortunate tragedies.

After learning of her own adoption at a late age, Chris aids a woman determined to unlock the mystery behind her birth story; a desperate mother enlists Lisa's help to locate her first-born son, hoping to reunite him with his full-blooded siblings.

Lisa faces many challenges when she helps a woman locate her father -- starting with his identity; a woman seeks Chris' help to find her mother, hoping the similarities she read in her adoption paperwork are not just a fantasy.

Chris aids a woman's search for her father after being shuffled through 28 foster homes; two radically different sisters, adopted into the same family, seek Lisa's help to search for their biological mother.

Pregnant detainees await trial; Jamie, a mother of four struggles for visitation rights; Tanya requests house arrest to prepare for the birth of her son.

Latoya struggles with giving up her baby for adoption; Esther is sent to disciplinary segregation.

The Las Vegas University Medical Center is the only Level One Trauma Center in Nevada.

Up-close look in the only Level One Trauma Center in Nevada.

The staff and cases that come through at the Las Vegas University Medical Center.

The staff and cases that come through at the Las Vegas University Medical Center.

A driver wrecks their car into a restaurant patio; medics rescue a 25-year-old man from a burning vehicle; a ventriloquist barely misses getting hit by a car.

The trained medical physicians and staff at the Las Vegas University Medical Center treat patients in the Pediatric Emergency Department.

A family of four is on the brink of collapse under the weight of the parents' hoarding; a man denies he's addicted to auctions and garage sales.

Two women seek help for their compulsive hoarding problems.

Bennie and Rhonda have lived decades of compulsive hoarding that have driven their loved ones away.

Laura and Margaret are both mothers and extreme hoarders; their parallel obsessions have made them prisoners in their own homes while tearing their families apart.

Deborah and Mary both start hoarding in the wake of personal tragedies; ever since Deborah killed her drug-addicted boyfriend in self-defense, she and her son have lived amid growing piles of trash and unused possessions.

9/11 trauma was the trigger for one woman; the lasting effects of a brain hemorrhage.

Bennie and Rhonda have lived decades of compulsive hoarding that have driven their loved ones away.

Laura and Margaret are both mothers and extreme hoarders; their parallel obsessions have made them prisoners in their own homes while tearing their families apart.

Deborah and Mary both start hoarding in the wake of personal tragedies; ever since Deborah killed her drug-addicted boyfriend in self-defense, she and her son have lived amid growing piles of trash and unused possessions.

9/11 trauma was the trigger for one woman; the lasting effects of a brain hemorrhage.

A family of four is on the brink of collapse under the weight of the parents' hoarding; a man denies he's addicted to auctions and garage sales.

Two women seek help for their compulsive hoarding problems.

Cindy is desperate to have Dr. Brad fix her stumpy foot; Gregory has open wounds on both feet and hopes Dr. Ebonie can heal them; Glen's feet are split down the middle, and Dr. Brad is determined to find a solution to ease his pain.

Dr. Ebonie, Dr. Brad and Dr. Sarah have their hands full with three extreme and challenging surgical cases, including crossed toes, unknown masses and even a ruptured Achilles, and they each try to make sure their patients will walk normally again.

A woman with twisted toes; a man with Frankenstein feet; a mother with extreme calluses.

Dr. Brad and Dr. Sarah have their hands full when they are faced with twins who have identical toe problems; a boy with extremely itchy feet and a woman born with a massively large toe are desperate for Dr. Ebonie's help.

A man with horns on his feet, a woman whose foot went through a windshield, and a guy who has dead man's feet create mysterious challenges for Dr. Brad and Dr. Ebonie.

Dr. Ebonie tries to help Devon, whose foot is so misshapen he calls it Igor; in New Jersey, Dr. Sarah treats a woman with killer corns and twisted toenails; Dr. Brad helps a woman with toes spread so far apart they make a peace sign.

Chiropractor Dr. Colón treats Liana, a cane-bound woman suffering from involuntary tremors; Sarah's obsession with corsets causes her migraines; Amy, a little person, can no longer walk on her own; Brenda has uncontrollable gas.

Dr. Colón helps a woman who cannot keep her joints in place; a new mother suffers from a tragic boat accident; a bodybuilding leukemia survivor; a constipated baby.

Dr. ColÃ3n faces more chiropractic challenges when she treats a woman with CMT who hopes to stand at her daughter's wedding, a big breasted woman with extreme neck pain, and the show's sound man, who was born with cerebral palsy and an uneven body.

A young man has strange growths; toddler rapidly gains weight.

Harry is born healthy but his body starts transforming; Sadie is on the brink of starvation.

A girl is born with shocking deformities; a college student suffers from fluid around his heart and lungs.

A woman experiences strange symptoms after breast reduction surgery.

An infant's hip hurts mysteriously.

A young mother begins to have panic attacks and has a seizure; she experiences episodes of paranoia and delusions after being released from the hospital.

A woman suffers for years with a constant belching problem.

A young child does not respond to pain; a woman experiences unexplained seizures.

A teenager's hair begins to fall out.

A young mother begins to have panic attacks and has a seizure; she experiences episodes of paranoia and delusions after being released from the hospital.

A woman suffers for years with a constant belching problem.

A young child does not respond to pain; a woman experiences unexplained seizures.

A teenager's hair begins to fall out.

A woman experiences strange symptoms after breast reduction surgery.

An infant's hip hurts mysteriously.

Gina and wife Beth live with Gina's mother, but she and Gina's sister blame Beth for Gina's spiraling weight problem; it will take all Gina's will to leave home for Houston to get Dr Now's help, to save her life and her marriage.

Sean has a massive growth protruding from his side and skin so stretched it's tearing apart, forcing his mother to change both of their lifestyles before he can be approved for surgery.

Donald has difficulty walking and relies on his parents to take care of him, so he gets motivated to begin his weight loss journey.

When Travis gets too big to walk down the aisle, he promises to give his wife a proper wedding; he gains more weight, leaving Dr Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.

Joyce needs home health care and hasn't left the house in three years; getting to Dr. Now in Houston is just the first step and when he prescribes therapy where Joyce must revisit an unhappy past with her mom; it might be more than she can handle.

Shantel's brother Carlton lives downstairs but she hardly ever sees him because at 600 lbs each, neither can do the stairs safely; to break free from a death spiral of codependent eating they need Dr. Now's help to reforge their sibling relationship.

Seana is 23 and nearly 700 lbs, living at her mom's house, depressed and anxious, her weight-gain threatening to take her last breath; Dr. Now can give her the tools she needs to live, but until she chooses life, no one can save Seana but herself.

At 600 pounds, Ashley has to move home so her mom can help her care for herself and her newborn daughter; Ashley must overcome a lifetime's worth of unfortunate circumstances and get Dr. Now's help in Houston.

Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of with her, but to break the cycle of pathological eating that left him nearly bed-bound, he'll have to face a piece of his past he has always kept secret.

Dominic's life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only Dr. Now can help him learn to face life's challenges without using food to cope.

Tommy wants to lose weight so he can marry his fiancee and have the life he always dreamed of with her, but to break the cycle of pathological eating that left him nearly bed-bound, he'll have to face a piece of his past he has always kept secret.

Dominic's life is falling apart due to his food addiction; over 600 pounds and living in a van with his brother, he decides to leave California for Texas, where only Dr. Now can help him learn to face life's challenges without using food to cope.

At 600 pounds, Ashley has to move home so her mom can help her care for herself and her newborn daughter; Ashley must overcome a lifetime's worth of unfortunate circumstances and get Dr. Now's help in Houston.

Barbara's back lump became more noticeable after she lost 131 pounds; Bob has two painful bumps on his back; Hilda's depression is a result of the multitude of bumps on her eyelids; Art has one big bump on his head that he covers up with hats.

Taylore is a beautiful young woman who has unsightly elf-like bumps on her ears; Jose never goes out because of the baseball-sized lump on his head; Ken is covered in painful bumps that make it difficult to do everyday things.

Angelina has a huge chest lump under her left breast; Delano has a football-sized mass on his back.

Melissa tries to cover a huge lipoma with a sweatshirt for years; Tyler's fear of cancer keep him from having his huge head lumps diagnosed; Tahj is covered in painful boils; Amber has ear keloids that take control of her life.

Ronen's mysterious lump above his knee is one of the largest Dr. Lee has ever seen; Amber suffers from a debilitating skin disease that no one understands; Sandy has a neck lump she calls Tommy; Kristy's eyelid cyst is ruining her life.

Half of Mary's body is a size 18 while the other half is a size 8; Anthony's cyst is in the area called the "Triangle of Death;" Shane wants to get a lump off his back; Brandi is anxious about getting a lump removed from her chest.

Belinda's lump on her neck causes her to basically be immobile; Nicole won't get married until she gets her armpit lump removed; Adela's chest and back are covered in wisdom spots; Nick foolishly removes a lipoma at home and now needs Dr. Lee.

Diane has tumors all over her body that have ruined her life; Will fears his shoulder lump will be ripped open at work; Anthony's daughters force him to get his lump examined; a woman detests her hideous varicose veins.

Taylor has a large bump at the base of her spine that is far more dangerous than she realizes; John jokes about his hip lump, but it's no laughing matter; Noelle had her ears stretched as a teen, but now wants them repaired.

Louis is a veteran who is covered in scaly, dry skin that makes him feel like an alligator; Irais's kids are bullied because of the embarrassing growth on her head; Johnny has been living with a stubborn lump on his back for too long.

Patrick's nose is covered by huge bumps, and he can barely breathe; Aziza and Lauren are friends who bonded over their matching wrist lumps; Joe has a mound in the middle of his forehead that looks like a third eye.

April is covered in bumps that disfigure her arms; Genner flies all the way from the Philippines to have Dr. Lee help with his bumpy nose; Chris suffers from psoriasis that nearly covers his body and a bump on his head.

Matt has a skin condition that causes tumors to grow all over his body; Yamileth hasn't pursued her dreams because of the lump on her neck; Pat is covered with dark spots from her neck to her abdomen; Jennifer has a unicorn bump on her forehead.

Amber has hundreds of tumors on her face; Antonio has a mound on his spine and is afraid it might be impossible to remove; sisters Cheri and Janice both suffer from possibly matching lumps; Tatiana has an embarrassing bump on her butt cheek.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Lisa has a horn growing out of the back of her head and fears that it could be cancer; Victor has a bulbous lump on his chest; Chuck has a Popeye-shaped bump on his arm; Christian and Jonathan are teenage brothers with matching lumps.

Dr. Sandra Lee treats Heather, who has a huge growth on her leg and fears removing it could leave a keloid scar; Paul has a giant hump on his back.

Rhonda has bumps all over her head, including a horned growth that has her deeply concerned; Fred has a mysterious condition on his hands and has not been able to get answers from any doctors; Kevin has a huge lump protruding from his hip.

Jen has substantial growths on her ears that cause her depression, pain and vertigo; Juliet is under emotional distress because of the bumps all over her neck and chest; Gerald has a mysterious, kiwi-size lump on his middle finger.

Matt has a skin condition that causes tumors to grow all over his body; Yamileth hasn't pursued her dreams because of the lump on her neck; Pat is covered with dark spots from her neck to her abdomen; Jennifer has a unicorn bump on her forehead.

Amber has hundreds of tumors on her face; Antonio has a mound on his spine and is afraid it might be impossible to remove; sisters Cheri and Janice both suffer from possibly matching lumps; Tatiana has an embarrassing bump on her butt cheek.

Follows Maria and Teresa Tapia, conjoined twins from the Dominican Republic, as they travel to Richmond, Virginia to undergo separation surgery.

Stories of three very different sets of twins incorporate their lives since being surgically separated.

Kendra Herrin and her sister, Maliyah, were born attached at the abdomen and pelvis; doctors use a groundbreaking surgical procedure to separate the girls.

A newlywed couple is moving cross-country when the young wife, not knowing she is pregnant, discovers she is in labor.

Victoria suddenly goes into labor at her mother-in-law's house, never suspecting she was pregnant.

Ressa collapses and goes into a coma after a miscarriage five months earlier; she has an eclamptic seizure caused by her full term baby.

Alicia barely survives a harrowing car accident. Then, just 18 months later, a surprising pregnancy threatens the life of her newborn.

Melissa is rushed to the hospital thinking she might be having a miscarriage; she gives birth to an unexpected baby in the backseat.

Jenna is rushed to the hospital to find out she is in labor and at a hospital that hasn't delivered a baby in 15 years.

A student's head is impaled by a trophy deer's antlers; a semi-conscious car crash victim; a woman with an allergic reaction.

A man injured in a medieval role playing battle has a sword impaled in his head; a critically ill patient is so afraid of germs he won't allow doctors to treat him; two patients with the same life-threatening symptoms.

A doctor treats three gunshot victims who claim be innocent bystanders; a doctor must perform emergency brain surgery on his first day; a bride-to-be suddenly slips into a diabetic coma.

A woman stops eating because she believes she is dead; a runner goes blind in one eye during a marathon; an ER tech's stroke-like symptoms.

A woman believes her neighbors want to kill her; a man is near death after an arrow pierces his chest; two women with swollen abdomens refuse to explain the cause of their pain.

A circus sword-swallower suffers from a persistent case of hiccups; a mother and daughter mysteriously collapse in the ER; a woman loses control of her legs at her daughter's graduation.

A woman who slept through the birth of her child, hopes to find a diagnosis for her sleeping condition; a man with giant genitals seeks help; a 2.5ft teenager hopes to find out what stalled his growth.

A boy born with no eyes; a separated conjoined twin adjusts to life after losing his twin brother; two brothers suffer from a very rare bone condition; a boy living with a huge facial growth finally gets a diagnosis.

In India, Hemlata Singh, gave birth to a boy with the head and arms of his dead twin attached to his chest; doctors try to save the newborn and separate him from his sibling's body.

A girl's rare disorder causes her eyes to fall out of her head; a man who grows branches from his hands and feet hopes to return home; a baby with a large face tumor.

The world's tiniest brothers find out if they'll ever be able to grow; conjoined twins seek separation surgery; a boy has a rare brain tumor; a girl living with a face tumor embraces her condition.

An unknown syndrome ages two boys rapidly; a man with a basketball sized tumor gets surgery; a woman with a giant leg finds love.

In India, Hemlata Singh, gave birth to a boy with the head and arms of his dead twin attached to his chest; doctors try to save the newborn and separate him from his sibling's body.

A girl's rare disorder causes her eyes to fall out of her head; a man who grows branches from his hands and feet hopes to return home; a baby with a large face tumor.

An unknown syndrome ages two boys rapidly; a man with a basketball sized tumor gets surgery; a woman with a giant leg finds love.

A woman who slept through the birth of her child, hopes to find a diagnosis for her sleeping condition; a man with giant genitals seeks help; a 2.5ft teenager hopes to find out what stalled his growth.

A boy born with no eyes; a separated conjoined twin adjusts to life after losing his twin brother; two brothers suffer from a very rare bone condition; a boy living with a huge facial growth finally gets a diagnosis.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Zsaylnn needs to lose weight to be the mother her daughter deserves; her husband loves large women and does not support her goals.

A woman battles severe depression and has not left her Chicago basement in two years; the hope of having a life-changing surgery.

Kenae' is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae' turns to food to fill the void.

Krystal begins overeating to shield herself with a protective layer of obesity after suffering years of abuse; once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.

Isaac helped raise his siblings after his mom suffered a debilitating stroke when he was 10. While learning to cook for his family, he began comfort-eating. Now to avoid eating himself to death, Isaac must learn to take care of himself for a change.

A lifetime of abuse has left Michael anxious and afraid to leave the house; with the help of his devoted wife, he must follow Dr. Now's program to keep from eating himself to death.

Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden; Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live.

Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can't get through to her, the only thing that might help her break the cycle is a once-in-a-lifetime turn of events.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

Irene had to move back in with her son because her weight made it unbearable to live on her own. When Dr. Now can't get through to her, the only thing that might help her break the cycle is a once-in-a-lifetime turn of events.

Through tough times, food has always been Tammy's friend; now she has gotten so big that her daughters and mother have moved home to care for her, and unless Dr. Now can get her to confront her grief, food might be her killer.

Shannon's husband loves her the way she is, but that may not help because she's 700 pounds and bedridden; Dr. Now knows it's not easy to break a toxic cycle of overfeeding and enabling, but that's what needs to happen if Shannon wants to live.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

Christina has not left her house in two years due to her size; she has eaten herself into a state that will soon kill her if she does not change.

James comes from a long line of family obesity; he is determined not to die as his sister and father did; he hopes to get gastric bypass and even start dating again.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.