Gastric surgery freed Brittani from her housebound life, but to achieve her ideal body she'll have to endure two more painful surgeries; Sean's super-obesity nearly killed him.

Surgery enables Teretha to return to family in Detroit, but it soon threatens to undo all her progress; Chad is back on the road, but his old diet is a risk.

Ontreon hopes that surgery can make him a better husband to his wife Musa, but he struggles to move past the grief that's blocked him for years; Wess is doing great post-surgery, but his next goal is crucial to his success.

Erica regrets not keeping a promise to her mom and hopes her siblings will help, but they're reluctant based on her past failures.

At over 700 pounds, Teretha's life is confined to a bed, which is a long way from her former job representing Detroit's healthy eating program; a gastric bypass will hopefully save her life.

Milla is bedridden and dependent on her husband and five kids, who can't resist her unending requests for junk food.

Cillas' food addiction is getting in the way of his ability to be there for his fiancée, Jessica, and her three daughters; if he doesn't lose weight soon, he knows he'll lose either his girls or his life.

Gina and wife Beth live with Gina's mother, but she and Gina's sister blame Beth for Gina's spiraling weight problem; it will take all Gina's will to leave home for Houston to get Dr Now's help, to save her life and her marriage.

Twenty years after her father died as the result of a botched weight-loss surgery, Carrie is on the brink of eating herself to death; she must face the fear and grief of losing her father and end a cycle of toxic behavior with her husband, Chris.

Thederick has become housebound from eating and only goes outside to greet the ice cream man; after a recent hospital scare, it's finally clicked that if Dr. Now's program doesn't work for him, then nothing will.

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

Jeanne lives in an unhygienic household with her mother and schizophrenic father; at well over 600 pounds, Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.

James B, grew up eating rich Haitian food and loves it with a passion; James needs Dr. Now's help to diminish that love in order to survive, but a death in the family sends James retreating back to the comforts he knows.

Jeanne lives in an unhygienic household with her mother and schizophrenic father; at well over 600 pounds, Jeanne might never get weight-loss surgery as she runs into several obstacles, especially after an unexpected death in her family.

Mike was born with a talent for sports and an omnivorous appetite to match; after his football dreams were dashed by multiple concussions, Mike packed on over 700 pounds, now he must find a new purpose in life to avoid succumbing to pain and regret.

Las Vegas paramedics Calvin Griffin, an 11-year veteran, and Walt West and Melanie Isom, two rookies with less than a year's experience.

Washington, D.C., emergency medical technicians often work on the front lines of some of the United States' most dangerous streets.

Paramedics work the streets of Tampa, Fla., by truck or helicopter, and confront everything from a bull goring to a minor concussion.

A shootout leaves a police officer clinging to life; a cowboy and cupid help a she-devil in distress; a zip-line guide falls 80 feet to the canyon floor.

Doctors retrieve a stolen Rolex from a very private spot; a pick-up turns deadly when a cabbie is shot multiple times; a dirt-bike accident in the desert leaves a 52-year-old thrill-seeker clinging to life.

A brutal assault could end a star athlete's career, a 28-year-old man is hit in the head by a flying baseball bat; and a Vegas chef falls asleep with a loaded gun.

Charmaine from Trinidad suffers from one of the most extreme cases of neurofibromatosis ever recorded; tumors cover every inch of her body and obstruct her ability to breathe and swallow; without surgery, these growing tumors threaten her life.

Thirty-year-old Alexandra has a 20-pound, sagging tumor that starts at the back of her neck and now reaches below her waist; as the tumor on Claudia's backside continues to grow, so does the urgency for surgeons to remove it.

Despite his family's pleas, Marlow explores a high-risk surgery to remove a facial tumor; Amy has let the tumor on her back grow for more than 17 years; after finally making the decision to remove it, she learns that now it might be too late.

Kylie has weight loss surgery that leaves her with a life-threatening infection; Anna fears her extra skin makes her look unprofessional.

Sarah turned to food for comfort during her damaging childhood, but her weight loss left her with sagging skin; Roger overcame a challenging life to raise his children, but his weight loss gave him restricting excess skin.

Annette lost over half of her body weight, but her excess skin is a painful reminder of years of overeating; Callisto lost 250 pounds and became a model, but the shame of her loose skin put her passion and marriage on hold.

Mary hopes skin removal surgery will rid her of the painful memories of her obese life; after a car accident, Lora goes through recovery, obesity and gastric bypass surgery, but gets left with stretched skin and terrible scars.

Sisters Jessica and Melissa are left with massive excess hanging skin after growing up morbidly obese; Matt lost everything he cherished, but after losing weight, his excess skin keeps him from returning to life.

Sean's nightmare keeps coming true, he can't stop pooping himself on stage; Tired of dealing with explosive bowels, Sean asks Dr. Hodges for help; Latoya wants to spend time with her kids again which means the 10 pound mass between her legs needs to go.

AliceJean's botched lap band removal left her with six belly buttons that form a golf course on her stomach; Simone seeks help for her uncontrollable vomiting.

After a botched lap band surgery, Christina has been blending her meals for over a decade; Dr. Caplin assists a patient whose tummy tuck has left her with a butt crack for a stomach.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches; Robert has a tomato-sized growth on his butt cheek that causes him pain; Sharon has an embarrassing, stinky, leaking cyst under her breast.

Sean's nightmare keeps coming true, he can't stop pooping himself on stage; Tired of dealing with explosive bowels, Sean asks Dr. Hodges for help; Latoya wants to spend time with her kids again which means the 10 pound mass between her legs needs to go.

AliceJean's botched lap band removal left her with six belly buttons that form a golf course on her stomach; Simone seeks help for her uncontrollable vomiting.

After a botched lap band surgery, Christina has been blending her meals for over a decade; Dr. Caplin assists a patient whose tummy tuck has left her with a butt crack for a stomach.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches; Robert has a tomato-sized growth on his butt cheek that causes him pain; Sharon has an embarrassing, stinky, leaking cyst under her breast.

Mary hopes skin removal surgery will rid her of the painful memories of her obese life; after a car accident, Lora goes through recovery, obesity and gastric bypass surgery, but gets left with stretched skin and terrible scars.

Sisters Jessica and Melissa are left with massive excess hanging skin after growing up morbidly obese; Matt lost everything he cherished, but after losing weight, his excess skin keeps him from returning to life.

A woman with twisted toes; a man with Frankenstein feet; a mother with extreme calluses.

Dr. Brad and Dr. Sarah have their hands full when they are faced with twins who have identical toe problems; a boy with extremely itchy feet and a woman born with a massively large toe are desperate for Dr. Ebonie's help.

A man with horns on his feet, a woman whose foot went through a windshield, and a guy who has dead man's feet create mysterious challenges for Dr. Brad and Dr. Ebonie.

On the day before Halloween, Abbigale gives birth when she didn't know she was pregnant.

While attempting to recover from the stress of getting mugged and a bad fall, Nikki finds out she is pregnant and full term.

Paramedics rush Anna to a hospital on Christmas Eve for what she thinks is food poisoning only to discover she's 41 weeks pregnant, in labor and didn't know it.

A woman who has accepted that she may never have a child is rushed to a hospital with cramps attributed to work stress and is shocked to find out she's pregnant and in labor.

Stabbing pains in the pelvis send a woman to an ER, where she discovers she has given birth, without realizing she was pregnant.

Tiffany thinks the abdominal pain she is having is from a rupturing cyst, but it's actually a child she didn't know she was carrying.

A woman goes into delivery while in a cab; a life-threatening pregnancy; twin sisters have their babies on the same day.

A best friend's offer to be a surrogate results in a life-threatening pregnancy; a woman is bitten by a deadly snake three weeks before her due date; a cupcake famed for inducing labor.

A woman gives birth while trapped in an elevator; two truckers deliver a baby in a diner; a prolapsed umbilical cord threatens a baby's life.

A grandma-to-be acts as surrogate for her daughter's baby; a very premature baby arrives at a playground; a woman gives birth at home.

A woman's arm burns from the inside out; a girl undergoes life-changing surgery to stop her neck from dislocating; a boy has a large facial tumor removed; with bonus content.

A man with half a torso learns if his rare bone-eating disease is back; a young girl undergoes surgery to stop her facial tumor from choking her; a boy is born with half a face.

A man with cold-like symptoms loses his limbs and lips; a young girl has a prematurely fused skull; a boy with brittle bones and a rare skin condition gets life-changing surgery; a woman suffers from a disfiguring birthmark; with bonus content.

A woman suffers from cyclical vomiting syndrome; a man with warts all over his body searches for cures; a girl fights for a surgery that could allow her to speak for the first time; with bonus content.

A man passes out from abdominal pain; a woman helps solve the mystery of her estranged father's deadly symptoms; a group of delirious Civil War re-enactment soldiers arrives in the ER.

A wrist fracture turns into a medical mystery; two fishermen get stuck on the same lure; a cheerleader with a sprained finger nearly dies of an unexpected cause; a power outage foils the ER team's effort to get a dying patient to the OR.

The hospital is locked down when a nurse is shot in the ER; medics rush a bride from her wedding who is in an unexplained altered mental state; a doctor must perform a risky intervention to save the life of a teenage girl.

A teen football player suffers a stroke; a doctor remembers his first major trauma in the 1970s; a doctor tries to figure out what causes a patient's abdominal pain; a man who is run over twice by his wife.

A man passes out from abdominal pain; a woman helps solve the mystery of her estranged father's deadly symptoms; a group of delirious Civil War re-enactment soldiers arrives in the ER.

A wrist fracture turns into a medical mystery; two fishermen get stuck on the same lure; a cheerleader with a sprained finger nearly dies of an unexpected cause; a power outage foils the ER team's effort to get a dying patient to the OR.

The hospital is locked down when a nurse is shot in the ER; medics rush a bride from her wedding who is in an unexplained altered mental state; a doctor must perform a risky intervention to save the life of a teenage girl.

A teen football player suffers a stroke; a doctor remembers his first major trauma in the 1970s; a doctor tries to figure out what causes a patient's abdominal pain; a man who is run over twice by his wife.

A man with cold-like symptoms loses his limbs and lips; a young girl has a prematurely fused skull; a boy with brittle bones and a rare skin condition gets life-changing surgery; a woman suffers from a disfiguring birthmark; with bonus content.

A woman suffers from cyclical vomiting syndrome; a man with warts all over his body searches for cures; a girl fights for a surgery that could allow her to speak for the first time; with bonus content.

Cynthia, a single mother focused on raising five kids, comes to realize what her death would mean for their future.

Zsaylnn needs to lose weight to be the mother her daughter deserves; her husband loves large women and does not support her goals.

A woman battles severe depression and has not left her Chicago basement in two years; the hope of having a life-changing surgery.

Mercedes, who has severe lymphedema, must overcome trauma to lose weight.

When Travis gets too big to walk down the aisle, he promises to give his wife a proper wedding; he gains more weight, leaving Dr Now as Travis' only hope to lose weight and get the life he and his wife dreamed of having together.

Cindy is resistant to change and spends years creating a world that makes her feel safe; when her friend notices Cindy's health declining rapidly due to her size, she pushes Cindy to move to Houston and see Dr. Now.

Melissa has isolated herself at home and lost many friends to avoid feeling the shame of what her food addiction has done to her body; now, the only way to get her life back is to leave it behind to start a new one with Dr. Now's help in Houston.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father for help instead. Aaron must learn to care for himself to avoid eating himself to death.

Margaret's life at 700 pounds is in need of a jump-start; at age 35, she is a mama's girl; it's time for Margaret to get out of bed, overcome her food addiction and break away from the comfort of her mother so she can finally live her life.

Since the death of his mother, Aaron lives at home to care for his aging father, but due to his food addiction, Aaron has to heavily rely on his father for help instead. Aaron must learn to care for himself to avoid eating himself to death.

Living with his family, Lucas wants to spread his wings and fly, but at 600 pounds, he can't take off. All he does is eat and game, and if he wants to leave the nest and live a normal life, he needs Dr. Now's help to lose over 400 pounds.

Yaellie, 9, has itchy psoriasis on over 90 percent of her body; former U.S. Marine Matt has a large recurring lump in his armpit; twins Tracie and Stacie have numerous matching bumps on their heads that sometimes leak.

Joanne has been held back from success because of her forehead growth; Shakisha split her left earlobe after stretching it with gauges; Mike is a tough guy with a soft bump on his head; Dania's rhinophyma has kept her from enjoying her life.

James has a large, squishy lump on his forehead; Tanisha has a growth on her arm and itchy scars all over her body; Ed wants his stomach lump removed before his girlfriend gets out of prison; Justin has painful mystery bumps all over his head.

JD is a gentle giant with a pear-shaped mass hanging off of his ear; David has two bumps on his neck and one on his finger that give him pain; Julie hopes Dr. Lee can remove her large back growth so she can return to the sea.

Stephen's large, bulbous nose gets him unwanted attention, and he hopes Dr. Lee can help; Veronica wants to be free of secrets, including the bump on her butt; Marty has a large, 30-year-old growth on his shoulder that he is ready to remove.

Brittany has been called a monster due to her genetic condition that causes head-to-toe bumps; Leonardo has a fist-size growth on his head, but he is terrified of doctors; Tamyra has skin so thick that she shaves the bottom of her feet for relief.

Jaclyn has a lump on the back of her head that causes her emotional distress; Shane has a growth between his eyes that could put him in danger at his electrician job; Brittany has seen multiple doctors about the sores on her body with no answers.

Stacey's shoulder growth prevents her from being the playful teacher she once was; Matthew worries that his mysterious shin rash may be dangerous.

Lattyse was born with a mysterious growth above her eyebrow that gives her headaches. Robert has a tomato-sized growth on his butt cheek that causes him pain and discomfort. Sharon has an embarrassing, stinky, squirting cyst under her breast.

Keke is covered in bumps that make her embarrassed to be intimate with her husband; Jim is a widower with two lumps who wants them removed for himself and his late wife; Corey has been labeled a devil worshiper because of his forehead growth.

Monica returns for a second time in hopes that Dr. Lee can remove some more of her face growths; Ken has several large cysts on his head that he has tried to remove on his own; Maranda has a mystery skin sore that causes discomfort.

Corey is a drag queen and has a bump dangling from his booty; Adam has a semicircle of about a dozen cysts on his head that he covers with a hat; Virginia has large growths on both of her upper arms that make it difficult to travel in her RV.

Terry's nose growth has prevented him from meeting his grandkids; Remi has alligator-like skin and is not used to taking care of herself; Austin has an embarrassing birthmark right next to his eyelid; Mary Jo has a throbbing bump on her neck.

Roger has enormous growths on his nose that drip pus, attract flies, and are so large that he can barely breathe; Sandra and Jessie are sisters who bonded over their many undiagnosed face bumps.

Leonard has a bump on his arm that looks like it's breaking through the skin; Brandon has lumps on his head; Jess gets a lump on her butt after falling down the stairs.

Pop-up facts and behind-the-scenes secrets are revealed; Dr. Sandra Lee assists Matt with the tumors growing all over his body; Yamileth hasn't pursued her dreams because of her neck lump; Jennifer has a unicorn bump on her forehead.

Facts and behind-the-scenes secrets; Melissa tries to cover a lipoma with a sweatshirt; Tyler's fear of cancer keeps him from having his head lumps diagnosed; Amber's ear keloids have taken control of her life.

Gerard has nearly 100 lumps, varying in size, all over his body; no one has been able to help Gina with her bloody lesions; Eric calls the large bump on his head his on-off button.

Leonard has a bump on his arm that looks like it's breaking through the skin; Brandon has lumps on his head; Jess gets a lump on her butt after falling down the stairs.

Pop-up facts and behind-the-scenes secrets are revealed; Dr. Sandra Lee assists Matt with the tumors growing all over his body; Yamileth hasn't pursued her dreams because of her neck lump; Jennifer has a unicorn bump on her forehead.

Facts and behind-the-scenes secrets; Melissa tries to cover a lipoma with a sweatshirt; Tyler's fear of cancer keeps him from having his head lumps diagnosed; Amber's ear keloids have taken control of her life.

Gerard has nearly 100 lumps, varying in size, all over his body; no one has been able to help Gina with her bloody lesions; Eric calls the large bump on his head his on-off button.

Terry's nose growth has prevented him from meeting his grandkids; Remi has alligator-like skin and is not used to taking care of herself; Austin has an embarrassing birthmark right next to his eyelid; Mary Jo has a throbbing bump on her neck.

Roger has enormous growths on his nose that drip pus, attract flies, and are so large that he can barely breathe; Sandra and Jessie are sisters who bonded over their many undiagnosed face bumps.

After learning of her own adoption at a late age, Chris aids a woman determined to unlock the mystery behind her birth story; a desperate mother enlists Lisa's help to locate her firstborn son, hoping to reunite him with his full-blooded siblings.

Lisa faces many challenges when she helps a woman locate her father -- starting with his identity; a woman seeks Chris' help to find her mother, hoping the similarities she read in her adoption paperwork are not just a fantasy.

Chris aids a woman's search for her father after being shuffled through 28 foster homes; two radically different sisters, adopted into the same family, seek Lisa's help to search for their biological mother.

Lisa helps a man find his birth mother, hoping to answer why she placed him for adoption, but kept his three brothers; after turning to psychics for answers, a woman seeking details about her birth mom hopes Chris can separate truth from fiction.

A dramatic turn of events takes place as Chris and Lisa investigate two seemingly different cases; a chance discovery raises the tantalizing prospect that the mother and son they are helping may be looking for one another.

Krystal is keeping the baby a secret; Danie fears her dad will reject her baby.

Carmen is a struggling single mother; Jerline and her husband are unemployed.

Jen is pregnant again after a stillbirth; Chanda is afraid to tell her parents of her pregnancy.

Richanne is diagnosed with a brain tumor and pregnant; Paola's pregnancy could ruin her career.

Sandra relationship with her daughters; Dannielle risks her relationship with her grandfather.

Doctors treat a series of gunshot victims and a woman with vision and mobility problems at Wishard Hospital in Indianapolis.

Gang warfare and a high population of sick patients keep medical center workers on the move in Los Angeles.

Trauma patients flood the Tampa General Hospital during Gasparilla Day -- the city's version of Mardi Gras.

The work of the staff at Baylor University Medical Center in Dallas includes a rodeo champion who was trampled by a bull.

Joseph's neck lipoma gets in the way of everything he does; Rachel's condition gives her a full beard that she shaves daily; Summer has seven cysts, including one she calls her unicorn horn.

Tiffany has a rare condition that has left her in so much pain, she's couch bound; Brad's face is covered in nodules from a condition that affects less than one in a million people; Lydia's life is impacted by her excessive sweating.

Ramon's keloids on the back of his head are so large that he may require a skin graft if removed; Lauren has a condition that gives her bumps inside and outside of her body; Tiana has an unknown condition, giving her what looks like four breasts.

Tiana hopes Dr. Mercy can figure out how to get rid of her two extra breasts; Michael wants his giant patches of skin tags removed for his 40th birthday; Chandra's lipoma is weighing her down physically and emotionally.

Joseph's neck lipoma gets in the way of everything he does; Rachel's condition gives her a full beard that she shaves daily; Summer has seven cysts, including one she calls her unicorn horn.

Tiffany has a rare condition that has left her in so much pain, she's couch bound; Brad's face is covered in nodules from a condition that affects less than one in a million people; Lydia's life is impacted by her excessive sweating.

Ramon's keloids on the back of his head are so large that he may require a skin graft if removed; Lauren has a condition that gives her bumps inside and outside of her body; Tiana has an unknown condition, giving her what looks like four breasts.

Tiana hopes Dr. Mercy can figure out how to get rid of her two extra breasts; Michael wants his giant patches of skin tags removed for his 40th birthday; Chandra's lipoma is weighing her down physically and emotionally.

Trauma patients flood the Tampa General Hospital during Gasparilla Day -- the city's version of Mardi Gras.

The work of the staff at Baylor University Medical Center in Dallas includes a rodeo champion who was trampled by a bull.

Robin and Garrett started their weight-loss journeys together as aunt and nephew; almost four years later, they're like war buddies, striving to reach their target weights through a combination of shedding pounds and skin removal surgeries.

Melissa, mother of four, finds herself feeling overwhelmed due to a rocky marriage and an unexpected pregnancy; when Ashley's weight-loss journey hits a wall, she sets out to find new inspiration to get herself back on track.

Christina's weight loss threatens her life; after losing 300 pounds, Paula must endure more surgery to deal with a body entirely covered in loose and sagging skin.

After losing 250lbs, Nikki is on her way to skin surgery, but when a close friend dies from weight loss surgery, Nikki's progress is derailed by fears.

Devastated by the sudden loss of her son, Dottie's weight loss journey is in danger of going off track; June embarks on a plan to win approval for skin surgery; Melissa, Jessica and Matt prepare for skin removal surgery.

Charity's daughter is becoming dangerously obese; devastated by the death of her husband Elroy, Milla must find a way to finally qualify for gastric bypass; check-in with individuals who have undergone skin removal surgery.

Once 800lbs, housebound and alone, Joe is now engaged and planning a wedding; after losing over 300lbs, Pauline is on the verge of independence if only she can qualify for the skin surgery she needs so badly.

Surgery enabled Laura's independence, but the complications nearly killed her, and she's terrified about the next skin surgery; Chay revealed to her family she was transgender, but living life as an overweight woman.

A number of challenges seem to have cornered Betti Jo and her husband; Susan encounters a serious problem that can throw everything off track.

Over 11 years, Melissa has lost 500 pounds and saw her weight drop to 137 pounds; now facing marital problems, three pregnancies, and life as a single mom, Melissa is struggling with a 150-pound weight gain and finds herself at a crossroads.

A number of challenges seem to have cornered Betti Jo and her husband; Susan encounters a serious problem that can throw everything off track.

Over 11 years, Melissa has lost 500 pounds and saw her weight drop to 137 pounds; now facing marital problems, three pregnancies, and life as a single mom, Melissa is struggling with a 150-pound weight gain and finds herself at a crossroads.

Surgery enabled Laura's independence, but the complications nearly killed her, and she's terrified about the next skin surgery; Chay revealed to her family she was transgender, but living life as an overweight woman.

After overcoming a dependence on drugs and alcohol, sneaking food is Doug's last remaining vice; this husband and father must overcome his addictive personality to save his life and marriage.

Penny has been bedridden for four years and moves to Texas to have gastric bypass; her unwillingness to make lifestyle changes could mean failure.

Chuck weighs almost 700 pounds; he has had to downsize his business and his wife feels like a single-parent who is ready to leave him.

At over 600 pounds, Angie is trying to get to Houston to see Dr. Nowzaradan, in hope of getting weight loss surgery to save her life; family conflict and disagreements may stop her from being able to do what she needs before she even gets the chance.

Joyce needs home health care and hasn't left the house in three years; getting to Dr. Now in Houston is just the first step and when he prescribes therapy where Joyce must revisit an unhappy past with her mom; it might be more than she can handle.

Kenae is already big before her weight gain takes off after the death of her beloved mother; refusing to deal with the pain, Kenae turns to food to fill the void.

Krystal begins overeating to shield herself with a protective layer of obesity after suffering years of abuse; once a means of protection, her pathological eating now threatens to destroy her life if she doesn't get help.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

Dolly has pain all over, and the skin apron pulling on her abdomen is miserable, but her mom and others wait on her hand and foot.

Maja moves to Houston to undertake a difficult weight-loss journey with the support of her boyfriend, Christian; when Christian decides he's had enough and leaves Maja high and dry, she discovers that the only person she can count on is herself.

At 700 pounds, Ontreon has managed to keep going thanks to his faith in God, and he's training to become a minister; Onteon is hopeful but has to believe in himself.

Getting too hot can be fatal for twins Andrew and Brandon, who meet Josh, a fellow sufferer of Ectodermal Dysplasia.

Tiffany and Yajaira have Jarcho Levin Syndrome, which malformed their ribs and spines during infancy.

Born with Goldenhar Syndrome, Austin and Elena have been bullied for looking different, and feel isolated from other kids.

After a young man blows his nose, he becomes violently ill and passes out; his condition progressively worsens while doctors try to diagnose what's wrong before one more sneeze kills him.

A healthy pastor feels like he has had a heart attack every day for years; a friend gives advice and doctors try to solve the mystery.

Decades after a car accident, a woman loses the ability to speak; when her speech returns, she speaks with a foreign accent; one doctor thinks he knows why.

After Thomas Hicks sold over 200 babies illegally in the 1950s and 1960s, Jane Blasio works to reunite the stolen babies with biological families while trying to unearth secrets about Hicks himself.

Jane discovers a suspicious pattern of babies with extremely low birth weights coming out of the clinic; Chris finds out that Dr. Hicks may have hidden birth records in his mausoleum; Diane hopes to meet her biological father.

Jane and Lisa meet the first Hicks baby, Stephen Dilbeck; Chris and Sallie open the mausoleum in search of birth records rumored to be inside as they work on getting approval of an exhumation.

Lisa helps a man find answers about his adoption; a breast cancer survivor searches for her birth mother.

Lisa helps a woman locate her son, hoping to heal the broken heart she's had since placing him for adoption decades ago; a tragic beginning of a woman's life with her mother dying in childbirth has Chris searching for her father.

Lisa helps a man locate his birth mother hoping to answer why she chose to marry a man who didn't want to raise him; a woman searches for the biological mother who abandoned her at a babysitter's house when she was three months old.

The revelation of a man's adoption catapults his search for his biological roots, but his son's DNA only deepens the mystery; a woman enlists Chris' help to find the son she placed for adoption, hoping her decision was not in vain.

Sisters searching for their birth mother hope Chris can uncover the mystery of why they were taken from her when they were young; Lisa helps a mother find the daughter she placed for adoption, hoping the adoptive family she chose was the right one.

Frank didn't expect Susan to fill his house with clutter when she moved in; though her home of forty-eight years sits condemned just two blocks away.

Geoffrey lost his home and has 30 days to clear the clutter, or he will lose everything left inside.

Ken's girlfriend is giving him one last chance to clear out; Lea could lose her children if she cannot clean her clutter.

A father and son who both hoard; one faces jail time while the other could lose his newborn son.

Frank didn't expect Susan to fill his house with clutter when she moved in; though her home of forty-eight years sits condemned just two blocks away.

Geoffrey lost his home and has 30 days to clear the clutter, or he will lose everything left inside.

Ken's girlfriend is giving him one last chance to clear out; Lea could lose her children if she cannot clean her clutter.

A father and son who both hoard; one faces jail time while the other could lose his newborn son.

The revelation of a man's adoption catapults his search for his biological roots, but his son's DNA only deepens the mystery; a woman enlists Chris' help to find the son she placed for adoption, hoping her decision was not in vain.

Sisters searching for their birth mother hope Chris can uncover the mystery of why they were taken from her when they were young; Lisa helps a mother find the daughter she placed for adoption, hoping the adoptive family she chose was the right one.

Two families welcome a new child; two defiant boyfriends return while another slips away.

Nicole has a c-section and Mariah refuses to help; Kim goes through a painful labor and delivery; Lemhele and Shaniyah go back to therapy.

Nicole makes a controversial announcement; Kim deals with her grandmother; Shaniyah gets induced.

Kim's boyfriend is released from rehab; Nicole and AJ get married; Shaniyah and Lemhele struggle with two new babies in the house; Lorna has a difficult birth.

Flu symptoms strike down men in Fort Collins; an elderly woman returns from China with a disease.

A deadly fever spreads in California after an earthquake; a bacterial outbreak forces a giant food recall.

Soldiers return from the Middle East bringing a mutant bacterium; a severe illness in children.

University of New Mexico Hospital staffers treat victims of crime, accident and illness.

Medical staffers teach accident prevention throughout the community.

Mentally ill son attacks family; horse throws polo-player.

Stuntman has a bike accident; gang-war stabbing; car-crash victims; man gets burned in a camping accident.

A successful businesswoman suddenly seems to become possessed by demons; a young college student battles monstrous pain when she grows fingernails out of her hair follicles.

A mother becomes a recluse when every sound becomes deafeningly loud; a man's career is in jeopardy when he gets drunk without touching a drop of alcohol.

A dad is accused of child abuse when doctors discover his baby has broken bones; a vibrant teenage girl is unable to eat and is wasting away before her mother's eyes.