When murder strikes a young girl, police quickly make an arrest, but cutting-edge technology from NASA proves they have the wrong suspect behind bars.

A man is found strangled and burned in his San Antonio apartment and the killer thinks he has destroyed all the evidence.

When two men appear to die of heart disease six years apart, police notice they have one thing in common -- they were each married to the same woman.

Casino security cameras offer the final images of a woman just before she vanished without a trace.

A squashed tomato and a pinpoint reflection of light in a photo help catch a killer.

An ATM transaction allows Texas detectives to pinpoint a suspect in the slaying of a teacher, but a shoelace stolen from the victim's home proves to be the tie that binds her killer to the crime.

Ten years after the murder of a rock singer, forensic scientists use evidence collected to finally bring her killer to justice.

Stories from across the world and refreshing conversations.

Stories from across the world and refreshing conversations.

Melanie Zanona; Catherine Lucey; Isaac Arnsdorf.

A successful lawyer, Mormon family man, and father of five is shot down in cold blood at a Walgreens parking lot, but a closer look reveals a dirty office affair that turned into a dangerous game of Russian roulette.

Tattoo shop owner Dennis Abrahamsen is found brutally murdered and naked on a massage table in his home; evidence tells a story of a wild sex party gone wrong with a famous adult actress.

Mother of two Crystal McDowell vanishes as Hurricane Harvey rocks Houston; surveillance video leads investigators to her twisted killer.

Former model, Samira Frasch, was living a life of extravagance until tragedy struck; the mother of two is found dead at the bottom of her swimming pool and both her children are missing from the home.

Aspiring cosmetologist Shannon Graves is found dismembered inside a padlocked freezer but when another woman is spotted driving her car and going into her apartment, detectives discover a chilling cover-up.

Successful doctor and mom of two, Teresa Sievers, is found bludgeoned to death in her kitchen after returning home from a family vacation.

After a Michigan State University grad student disappears and is presumed dead, a professor of geological sciences helps police get the "dirt" on her killer.

When a man's wife kills herself 14 years after his college sweetheart committed suicide, police start to get suspicious.

A woman shot in her driveway had recently rejected a co-worker half her age.

A pair of tennis shoes are found near a victim who had been stabbed on the beach, less than ten yards from her hotel.

Three fingerprints on a window screen are enough for a print examiner to uncover the work of a serial killer.

With a long list of suspects, forensic experts agree on one thing in this brutal murder: the killer knew his victim.

The only lead to finding a serial killer on the loose is a bloody fingerprint on the body of a victim.

Groundbreaking tests reveal the race, eye color and hair color of the person responsible for killing two young women on Halloween night.

A convicted arsonist claims his innocence and with no lawyer, no money and only a fifth-grade education, sets out to prove it.

A canine behaviorist uses the family dogs, who are the only witnesses, to find the murderer of their owner.

Investigators see through a killer trying to cover his tracks by staging the crime scene to learn what really happened.

A young girl beaten after watching her grandmother killed, identifies the wrong person; years later she tries to change her statement.

In 1984 police failed to convict the murderer of a college student. New technology may finally help the police to catch her killer.

Police investigate a young woman found murdered two weeks after reporting a road rage incident; evidence leads not to the aggressive driver, but one of their own.

When a single mother is murdered, her brother vows to find the person responsible for the death of his sister -- even if it takes more than 30 years.

A husband and wife get shot and their 16-year-old daughter manages to escape, but investigators suspect she may be involved in the murder.

A woman shot in her driveway had recently rejected a co-worker half her age.

A pair of tennis shoes are found near a victim who had been stabbed on the beach, less than ten yards from her hotel.

Three fingerprints on a window screen are enough for a print examiner to uncover the work of a serial killer.

With a long list of suspects, forensic experts agree on one thing in this brutal murder: the killer knew his victim.

The only lead to finding a serial killer on the loose is a bloody fingerprint on the body of a victim.

Groundbreaking tests reveal the race, eye color and hair color of the person responsible for killing two young women on Halloween night.

A convicted arsonist claims his innocence and with no lawyer, no money and only a fifth-grade education, sets out to prove it.

A canine behaviorist uses the family dogs, who are the only witnesses, to find the murderer of their owner.

Investigators see through a killer trying to cover his tracks by staging the crime scene to learn what really happened.

A young girl beaten after watching her grandmother killed, identifies the wrong person; years later she tries to change her statement.

In 1984 police failed to convict the murderer of a college student. New technology may finally help the police to catch her killer.

Police investigate a young woman found murdered two weeks after reporting a road rage incident; evidence leads not to the aggressive driver, but one of their own.

When a single mother is murdered, her brother vows to find the person responsible for the death of his sister -- even if it takes more than 30 years.

A husband and wife get shot and their 16-year-old daughter manages to escape, but investigators suspect she may be involved in the murder.

Numerous suspects emerge after someone starts targeting law enforcement officers in a peaceful Texas county.

An Illinois mother and her two young children are brutally murdered in their beds, and lurid threats are spray painted all over the walls of the crime scene.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The summer of 1985 was one of the hottest Los Angeles had seen in a century. But terrified residents weren't sleeping with the windows open; a killer known as the "Night Stalker" was on the loose.

A tip from a teenage boy leads to the identity of the Night Stalker and twenty-four hours later a mob of angry citizens track him down and capture him.

Desperate for answers community members live in terror waiting for the man dubbed the Co-Ed Killer to strike again.

In April 1973, Edmund Kemper, 24, murders six coeds in and around the city of Santa Cruz, Calif., shaking the community to its core.

The story of the millionaire heir to a vast real estate fortune who has been linked to the deaths of his wife, his best friend, and his neighbor.

Six weeks after jumping bail in Galveston, Texas, Robert Durst is caught on a store security camera in Pennsylvania shoplifting a sandwich and is quickly sent back to Galveston to stand trial for the murder of his neighbor, Morris Black.

After 10 years, a witness decides to do the right thing about the rape and murder of a young hairdresser.

Police investigate the possibility of a hate crime when two women go missing and are later found murdered.

When a human skeleton is found on marshland and determined to be at least 18 months old, an inventive computer consultant gives her a face and name.

A killer places all the incriminating evidence to the murder in a plastic bag, hoping it will float down the river.

A woman's body is found inside a burned mobile home and the autopsy reveals she was beaten, making this a murder.

Security guard who disappeared from his post was found a year later in a remote camp site; a decade later, a phone call and a paint smear on his boot helped scientists determine what happened during his final moments.

When three students are brutally murdered close to campus, investigators must determine what the women had in common before their serial killer strikes again.

Police get a big break when Mother Nature aids their investigation into the murder of a woman at her business.

Eyewitness to real estate agent's murder is put under forensic hypnosis in an attempt to help him recall the killer's face.

Police launch a search for a killer after a teenager returns home to find his father's body in a pool of blood.

Pathologist examining the death of a politician who was running for re-election finds tiny puncture wounds at the autopsy.

A Naval officer who threatened to go public with tales of on-the-job sexual harassment and assault is brutally murdered, but when investigators find the allegations could be part of an elaborate scheme for money, they turn to forensic science.

A few drops of blood are the only clues a man's female killer leaves behind, but years later and hundreds of miles away investigators hear an intriguing story about an exotic dancer who got away with murder.

After police identify a murder victim thanks to her butterfly necklace, they discover several co-workers had vendettas against the victim.

After 10 years, a witness decides to do the right thing about the rape and murder of a young hairdresser.

Police investigate the possibility of a hate crime when two women go missing and are later found murdered.

When a human skeleton is found on marshland and determined to be at least 18 months old, an inventive computer consultant gives her a face and name.

A killer places all the incriminating evidence to the murder in a plastic bag, hoping it will float down the river.

A woman's body is found inside a burned mobile home and the autopsy reveals she was beaten, making this a murder.

Security guard who disappeared from his post was found a year later in a remote camp site; a decade later, a phone call and a paint smear on his boot helped scientists determine what happened during his final moments.

When three students are brutally murdered close to campus, investigators must determine what the women had in common before their serial killer strikes again.

Police get a big break when Mother Nature aids their investigation into the murder of a woman at her business.

Eyewitness to real estate agent's murder is put under forensic hypnosis in an attempt to help him recall the killer's face.

Police launch a search for a killer after a teenager returns home to find his father's body in a pool of blood.

Pathologist examining the death of a politician who was running for re-election finds tiny puncture wounds at the autopsy.

A Naval officer who threatened to go public with tales of on-the-job sexual harassment and assault is brutally murdered, but when investigators find the allegations could be part of an elaborate scheme for money, they turn to forensic science.

A few drops of blood are the only clues a man's female killer leaves behind, but years later and hundreds of miles away investigators hear an intriguing story about an exotic dancer who got away with murder.

After police identify a murder victim thanks to her butterfly necklace, they discover several co-workers had vendettas against the victim.

A young Texas teenager and her boyfriend are brutally attacked on Valentine's Day; she is found dead while her boyfriend escapes; the case goes cold for nearly 50 years before a new forensic test exposes a family man with a dark secret.

Three Indiana construction workers are found shot on a work site.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Monica Massaro is found stabbed to death in her Bloomsbury, N.J., home, rocking the residents of the quintessential small town to their core.

After Nikki Halpin is beaten to death in her Safety Harbor, Fla., home, a mysterious voice on a 911 recording leads detectives to an unlikely suspect.

When Brittany Loritts is murdered, the investigators find that the family home is built on buried secrets.

A young woman is killed and luck leads them to a killer with evil intentions.

Man found gunned down in his home and it takes more than two years to nail a killer from his past.

The body of an eight-year-old is found near a rural country road.

The brutal murder of a construction site foreman looks like the work of a disgruntled employee, but forensic science points to an unlikely suspect.

A shooting victim mutters the name of her apparent assailant before dying, but fingerprint comparisons, handwriting analysis, ballistics and DNA testing show someone else close to home is the true killer.

A woman tells investigators that a man broke into her home wearing only underwear and gloves, killed her boyfriend, and raped and terrorized her.

After a Delaware man's mother is found dead, he tells a story that's so improbable police think it can't possibly be true.

A family vacation turns into a terrifying search for a missing wife and baby, then becomes a manhunt for a killer who committed a horrific crime.

A DNA dragnet catches a killer eight years after the kidnapping, rape and murder of a college coed in Oklahoma.

A nosy neighbor with a disturbing obsession becomes a suspect in a woman's murder at an upscale apartment complex; police discover an incredible link to an unrelated murder thousands of miles away.

A college student turns up dead and her boyfriend becomes a prime suspect when blood splatters are discovered on his wall.

Texas police hunt frantically for a brutal rapist. No one knows where he'll strike next, but given the increasingly violent nature of his crimes, he must be found soon.

When detectives find a mismatched button in relation to a woman's death, they know they can follow the clue back to the killer.

A woman heads home after church, but never makes it there alive, triggering a homicide investigation.

Volunteers and police spend weeks searching for a missing girl. A psychic later leads them to a field where the body was found.

Forensic investigators try to stop a killer who is apparently responsible for two slayings in a community in South Carolina.

When DNA proves that a man who practically admits to a brutal attack is innocent, police wonder why he was willing to take the blame.

The brutal murder of a construction site foreman looks like the work of a disgruntled employee, but forensic science points to an unlikely suspect.

A shooting victim mutters the name of her apparent assailant before dying, but fingerprint comparisons, handwriting analysis, ballistics and DNA testing show someone else close to home is the true killer.

A woman tells investigators that a man broke into her home wearing only underwear and gloves, killed her boyfriend, and raped and terrorized her.

After a Delaware man's mother is found dead, he tells a story that's so improbable police think it can't possibly be true.

A family vacation turns into a terrifying search for a missing wife and baby, then becomes a manhunt for a killer who committed a horrific crime.

A DNA dragnet catches a killer eight years after the kidnapping, rape and murder of a college coed in Oklahoma.

A nosy neighbor with a disturbing obsession becomes a suspect in a woman's murder at an upscale apartment complex; police discover an incredible link to an unrelated murder thousands of miles away.

A college student turns up dead and her boyfriend becomes a prime suspect when blood splatters are discovered on his wall.

Texas police hunt frantically for a brutal rapist. No one knows where he'll strike next, but given the increasingly violent nature of his crimes, he must be found soon.

When detectives find a mismatched button in relation to a woman's death, they know they can follow the clue back to the killer.

A woman heads home after church, but never makes it there alive, triggering a homicide investigation.

Volunteers and police spend weeks searching for a missing girl. A psychic later leads them to a field where the body was found.

Forensic investigators try to stop a killer who is apparently responsible for two slayings in a community in South Carolina.

When DNA proves that a man who practically admits to a brutal attack is innocent, police wonder why he was willing to take the blame.

A Texan who vows to live a reformed life after being released from prison is subsequently convicted of murder, despite insisting his innocence, so he uses forensic science from behind bars to try to prove his case.

An extremely successful California career woman keeps falling ill and doctors can't determine why, then after she dies they still have no explanation until they find a key figure in her life has been lying about his past.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

A mysterious tip leads police in Moore, Oklahoma to the Super 8 hotel; inside Room 120, they find a missing teenage boy, a box of condoms, lotion-and a married state senator.

19-year-old Sarah Stern vanishes just before Christmas and her car is found abandoned by Shark River; but the missing persons case soon turns into a homicide, and cops start focusing on a prom date.

Young mom of two, Kelley Stage, is found brutally murdered in her home after her husband returns from a night of poker; her young child witnesses the crime and reveals shocking details to investigators.

A young Colorado mom disappears on Thanksgiving Day and was last seen on grocery store surveillance with her baby; police soon uncover a brutal crime scene at her home and expose a twisted love triangle.

Tina Herrmann, her two children and a family friend disappear.

Barbara Kendhammer suffers fatal injuries after a heavy pipe impales the windshield of her car, but evidence at the crime scene tells a different story.

When a businessman is murdered, motives and suspects are plentiful. Was it simply a disgruntled employee or client? Or do some racy photos hold the clue to the crime?

A family break turns into a nightmare when the wife is found face-down in a lake. With no idea whether it was murder, an accident or suicide, police turn to a new forensic technique.

When friends see a woman in the back of a car flailing her arms and screaming, they assume she is having fun, but when they later come upon a jacket and a pool of blood, they realize they witnessed an abduction in progress.

An attack on a couple's home leaves the husband dead, the wife gravely injured and their son as a prime suspect; hundreds of miles away, a DNA sample may lead to the killer.

Detectives think they've solved a murder when they find the weapon and victim's blood in a man's flat, but the evidence may have been planted.

Detectives search for the bombers of two churches in Illinois, hoping that the materials used in the remnants of the handmade bombs will offer the clues to catch the culprits.

Initially, there were no clues in the murder of Florida college student Michelle Herndon, until a small needle mark was found on the victim's arm.

A woman is stabbed a hundred times and her body positioned in a suggestive manner. This could be a hate crime against women.

Police are able to create a composite sketch of a man burnt beyond recognition. But tracking the killer is more challenging.

By cutting a strand of a murdered man's hair into sections, forensics reveal a record of his last six months alive, and find he was frequently ingesting huge amounts of arsenic.

A bullet-riddled car, a missing driver, and no witnesses. An ambush or a random attack? The clue was something so tiny, it was measured in millionths of a meter.

Teenager is found half-naked with her throat slit. A single foreign hair found on her thumb may finger the killer.

Unsettling evidence is found in the rubble from a fire in a Seattle woman's apartment that is soon followed by another blaze just 100 feet from the first, with clues indicating a serial killer is at work.

Weeks after a student vanishes, the body of an unknown female is found in the ashes of a fire 700 miles away; an alert policeman realizes the crimes could be connected.

When a businessman is murdered, motives and suspects are plentiful. Was it simply a disgruntled employee or client? Or do some racy photos hold the clue to the crime?

A family break turns into a nightmare when the wife is found face-down in a lake. With no idea whether it was murder, an accident or suicide, police turn to a new forensic technique.

When friends see a woman in the back of a car flailing her arms and screaming, they assume she is having fun, but when they later come upon a jacket and a pool of blood, they realize they witnessed an abduction in progress.

An attack on a couple's home leaves the husband dead, the wife gravely injured and their son as a prime suspect; hundreds of miles away, a DNA sample may lead to the killer.

Detectives think they've solved a murder when they find the weapon and victim's blood in a man's flat, but the evidence may have been planted.

Detectives search for the bombers of two churches in Illinois, hoping that the materials used in the remnants of the handmade bombs will offer the clues to catch the culprits.

Initially, there were no clues in the murder of Florida college student Michelle Herndon, until a small needle mark was found on the victim's arm.

A woman is stabbed a hundred times and her body positioned in a suggestive manner. This could be a hate crime against women.

Police are able to create a composite sketch of a man burnt beyond recognition. But tracking the killer is more challenging.

By cutting a strand of a murdered man's hair into sections, forensics reveal a record of his last six months alive, and find he was frequently ingesting huge amounts of arsenic.

A bullet-riddled car, a missing driver, and no witnesses. An ambush or a random attack? The clue was something so tiny, it was measured in millionths of a meter.

Teenager is found half-naked with her throat slit. A single foreign hair found on her thumb may finger the killer.

Unsettling evidence is found in the rubble from a fire in a Seattle woman's apartment that is soon followed by another blaze just 100 feet from the first, with clues indicating a serial killer is at work.

Weeks after a student vanishes, the body of an unknown female is found in the ashes of a fire 700 miles away; an alert policeman realizes the crimes could be connected.

The body of a 24-year-old criminology student is found wrapped in a blanket alongside a desolate road in Brooklyn, N.Y.; police discover that the bouncer at a bar is her killer.

When a 79-year-old woman is found shot to death in her home, investigators initially suspect her husband or a violent neighbor; shell casings recovered at the scene and a high-tech database reveal an unlikely killer.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

In 1974, college-age women from the Pacific Northwest begin to disappear without a trace.

While serving time for aggravated kidnapping in Utah and facing first degree murder charges in Colorado, Ted Bundy escapes not once but twice from authorities.

Ted Bundy helps prepare his own defense, and his amateurishness may help him beat the rap or send him to the electric chair.

While the clock winds down, Bundy makes death row confessions in a desperate attempt to save his own life.

Almost two years after a romance begins between small-town waitress Jodi Arias and successful businessman Travis Alexander, Travis is found brutally murdered in his shower at home.

Four years after the vicious killing of Travis Alexander, ex-girlfriend Jodi Arias stands trial for his murder; millions of people are captivated by the emerging lurid details of Jodi and Travis' erotic relationship.

Investigators face a growing list of suspects after a beautiful flight attendant is brutally murdered in her own home.

Forensics investigate a clever inside job, in which finger prints, CCTV and DNA testing provide the keys to catching a thief and killer.

Florida authorities rely on DNA evidence to try to nail the killer of a woman who was abducted from her late-night job at a convenience store, raped and strangled.

A wild fire in a secluded parking lot leads police to discover a dreadful homicide, with the suspect's image caught by security cameras.

After a prominent Arizona surgeon is found stabbed to death outside his office, investigators uncover an unlikely suspect with deep pockets and an even deeper hatred for the doctor.

Police don't have a basis for comparison to match shoe impressions, blood drops and DNA evidence from a murder scene.

A masked gunman kills two members of a family and wounds two others after they interrupt his burglary at their upscale suburban home.

A killer leaves equally incriminating evidence at the scene when he meticulously wipes away his fingerprint and shoe impressions.

After a woman is found dead at a yacht club in California in an apparent case of love gone wrong, investigators discover her home life was as dramatic as films made in nearby Hollywood.

The brutal murder of a state park employee over $2,000 rattles her co-workers and tourists while leaving police to sift through hundreds of leads.

When evidence shows a woman's rape and murder, police must find the killer as well as the victim.

A week after a couple disappears from the beach, police get a mysterious lead from a robbery.

Fifteen years later, DNA technology leads to justice for a murdered woman and her savagely beaten 4-year-old daughter.

A quiet waitress who hasn't been to work in two days vanishes without a trace; police suspect a date gone wrong.

Investigators face a growing list of suspects after a beautiful flight attendant is brutally murdered in her own home.

Forensics investigate a clever inside job, in which finger prints, CCTV and DNA testing provide the keys to catching a thief and killer.

Florida authorities rely on DNA evidence to try to nail the killer of a woman who was abducted from her late-night job at a convenience store, raped and strangled.

A wild fire in a secluded parking lot leads police to discover a dreadful homicide, with the suspect's image caught by security cameras.

After a prominent Arizona surgeon is found stabbed to death outside his office, investigators uncover an unlikely suspect with deep pockets and an even deeper hatred for the doctor.

Police don't have a basis for comparison to match shoe impressions, blood drops and DNA evidence from a murder scene.

A masked gunman kills two members of a family and wounds two others after they interrupt his burglary at their upscale suburban home.

A killer leaves equally incriminating evidence at the scene when he meticulously wipes away his fingerprint and shoe impressions.

After a woman is found dead at a yacht club in California in an apparent case of love gone wrong, investigators discover her home life was as dramatic as films made in nearby Hollywood.

The brutal murder of a state park employee over $2,000 rattles her co-workers and tourists while leaving police to sift through hundreds of leads.

When evidence shows a woman's rape and murder, police must find the killer as well as the victim.

A week after a couple disappears from the beach, police get a mysterious lead from a robbery.

Fifteen years later, DNA technology leads to justice for a murdered woman and her savagely beaten 4-year-old daughter.

A quiet waitress who hasn't been to work in two days vanishes without a trace; police suspect a date gone wrong.

A young single mother is abducted from a gas station and is later found stabbed to death near an oil field; the detectives use shoe and tire impressions to weed out numerous suspects.

When a 23-year-old Marine dies in his bedroom, doctors initially believe a heart attack is to blame; when arsenic is found in his organs, his wife is charged with murder; a sharp attorney and toxicological testing uncover the truth.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The McNeil family lives a happy life until a member of their family is murdered and a relative's conspiracy surfaces.

The Sanchez family seems to have it all until one member is found dead.

Two members of the Kyne family call 911 separately to accuse each other of murder.

A family's good reputation is hiding dark secrets that will soon be revealed.

As a family battles with cancer, another killer lurks within their midst.

The Britts family's charmed existence falls apart when one member is killed and another is arrested.

The search for a missing exotic dancer led police to an isolated 75-acre site where someone had been shot and cremated, thus destroying all evidence... almost; piece of a foot provided enough DNA for a genetic profile and positive ID.

After years of suffering domestic abuse, a young woman is found murdered in her bathtub; among numerous clues, a hamburger bun proves the most incriminating.

Evidence that includes threatening emails, a missing person and an abandoned truck lead police to a woman's suspected killer, but they don't have the victim's body.

A woman has an accidental fall down a flight of stairs and appears to have hit her head, but the lack of blood splatter and misplaced shoes lead police to believe the fall was staged.

A church member gets gunned down after leaving choir practice; although witnesses see little and not much evidence exists, investigators learn that she had been having affairs for years.

When a man perishes in a fire while working in his garage, his death is initially ruled an accident until a forensic odontologist changes the direction of the case.

Lack of evidence compels investigators to look beyond the obvious when a woman is beaten to death at her in-laws house.

A man is found dead of an apparent suicide. But soon after, information emerges which reveals a much more menacing scenario.

A dismembered body is dumped on the side of the New Jersey Turnpike and before police realize it, bodies are turning up between two states.

A young bride-to-be is gunned down in her own home. The attack is personal and as investigators start digging, they uncover the man she loved was living a lie.

Tara Munsey went missing after a work shift at a Virginia restaurant and it is unknown if she ran away or if she was the victim of foul play.

An Ohio woman and her two daughters go missing while vacationing in Florida; their corpeses are found floating in Tampa Bay with a hand-written note by one of the victims; putting it on five billboards helps them find the killer.

Four young adults are murdered in an affluent Texas neighborhood, with little evidence but two people walking by dressed in black.

A young college student is found dead in her apartment and the autopsy rules the death a homicide by an unknown male suspect.

The search for a missing exotic dancer led police to an isolated 75-acre site where someone had been shot and cremated, thus destroying all evidence... almost; piece of a foot provided enough DNA for a genetic profile and positive ID.

After years of suffering domestic abuse, a young woman is found murdered in her bathtub; among numerous clues, a hamburger bun proves the most incriminating.

Evidence that includes threatening emails, a missing person and an abandoned truck lead police to a woman's suspected killer, but they don't have the victim's body.

A woman has an accidental fall down a flight of stairs and appears to have hit her head, but the lack of blood splatter and misplaced shoes lead police to believe the fall was staged.

A church member gets gunned down after leaving choir practice; although witnesses see little and not much evidence exists, investigators learn that she had been having affairs for years.

When a man perishes in a fire while working in his garage, his death is initially ruled an accident until a forensic odontologist changes the direction of the case.

Lack of evidence compels investigators to look beyond the obvious when a woman is beaten to death at her in-laws house.

A man is found dead of an apparent suicide. But soon after, information emerges which reveals a much more menacing scenario.

A dismembered body is dumped on the side of the New Jersey Turnpike and before police realize it, bodies are turning up between two states.

A young bride-to-be is gunned down in her own home. The attack is personal and as investigators start digging, they uncover the man she loved was living a lie.

Tara Munsey went missing after a work shift at a Virginia restaurant and it is unknown if she ran away or if she was the victim of foul play.

An Ohio woman and her two daughters go missing while vacationing in Florida; their corpeses are found floating in Tampa Bay with a hand-written note by one of the victims; putting it on five billboards helps them find the killer.

Four young adults are murdered in an affluent Texas neighborhood, with little evidence but two people walking by dressed in black.

A young college student is found dead in her apartment and the autopsy rules the death a homicide by an unknown male suspect.

Stories from across the world and refreshing conversations.

Stories from across the world and refreshing conversations.

Hard-working family man Chris MacCallum disappears while on a camping trip deep in the forest along the border of California and Oregon; when detectives start to unravel the mystery, all roads lead to an unthinkable suspect.

A young mother is reported missing by her lover; the search uncovers a violent predator.

A murdered young woman is found in the Gulf of Mexico and detectives spend years trying to identify her remains.

The bravery of a witness leads to solving the murder of a Miami nurse under very shocking circumstances.

A lifetime of violent secrets come into focus when a 91-year-old Washington VIP is found dead in her townhouse bathroom.

A woman is found shot to death in a Catskills vacation house just before it erupts in flames, hiding even more secrets.

A partially-clothed body is found along a horse path and it leads police on a four-state investigation which indicates the man's murder was based on a mistake.

The killer removed the computer that links him to the murder of a woman and her soon-to-be ex-husband that he had met online.

A community is shocked when police discover a woman raped and murdered in broad daylight on a public trail.

A real estate developer is shot and his wife becomes the prime suspect, until the bullet is linked to a weapon reported missing 20 years ago.

A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.

A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.

Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.

A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.

The investigation into the disappearance of flight attendant Helle Crafts leads to the murder conviction of her pilot husband.

Scientists and detectives use DNA to solve a string of rapes and murders.

Police use DNA profiles of seed pods from a truck to catch a killer.

Police believe they have a serial rapist and murderer, but DNA testing and research leads to another arrest and conviction.

In 1976, 182 war veterans in Philadelphia become hospitalized with pneumonia-like symptoms and 29 die; the disease resurfaces every few years.

After a wealthy Southern physician gets murdered with a baseball bat, his wife and a handyman become convicted of the crime.

In 1971, John List disappears after murdering his mother, wife and three children; he eludes the law for years until an age-scaled sculpture of the suspect and a true-crime TV program helps lead to his arrest in 1989.

An 11-year-old boy comes down with a fever and diarrhea after eating an undercooked burger; when his condition worsens, his mother drives him to a hospital and doctors discover E. coli destroying his body.

Florida police search for a serial rapist and murderer who left small red fibers on each of his 10 victims.

A real estate developer is shot and his wife becomes the prime suspect, until the bullet is linked to a weapon reported missing 20 years ago.

A body is found stuffed into a suitcase forcing the police to search though the landfill for another missing victim.

A woman goes missing for a month with the only clues being a set of keys, a fingerprint and a code.

Police discover a mask near the crime scene and hope that it leads to the killer of a funeral director.

A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.

The investigation into the disappearance of flight attendant Helle Crafts leads to the murder conviction of her pilot husband.

A killer assaults a young mother in her home, but despite meticulous washing of the crime scene, a single hair remains to lead authorities to the culprit.

The investigation into the disappearance of flight attendant Helle Crafts leads to the murder conviction of her pilot husband.

Scientists and detectives use DNA to solve a string of rapes and murders.

Police use DNA profiles of seed pods from a truck to catch a killer.

Police believe they have a serial rapist and murderer, but DNA testing and research leads to another arrest and conviction.

In 1976, 182 war veterans in Philadelphia become hospitalized with pneumonia-like symptoms and 29 die; the disease resurfaces every few years.

After a wealthy Southern physician gets murdered with a baseball bat, his wife and a handyman become convicted of the crime.

In 1971, John List disappears after murdering his mother, wife and three children; he eludes the law for years until an age-scaled sculpture of the suspect and a true-crime TV program helps lead to his arrest in 1989.

An 11-year-old boy comes down with a fever and diarrhea after eating an undercooked burger; when his condition worsens, his mother drives him to a hospital and doctors discover E. coli destroying his body.

Florida police search for a serial rapist and murderer who left small red fibers on each of his 10 victims.

Stories from across the world and refreshing conversations.

Stories from across the world and refreshing conversations.

Melanie Zanona; Catherine Lucey; Isaac Arnsdorf.

On Florida's Gulf Coast, young father Terrance Williams vanishes without a trace; Terrance's mother finds out that the last person to see her son before he disappeared has a curious connection to another man who went missing from the same town.

A 41-year-old mother of three was brutally stabbed nearly 200 times in front of her two youngest children; investigators reveal a sick and twisted motive behind the deadly rampage, and her daughter who witnessed the attack speaks for the first time.

Newlywed Lauren Phelps is stabbed 123 times as she fights for her life; her killer may blame his deadly rampage on cold medicine.

After Florida mother Gretchen Anthony, 51, goes missing from her home, surveillance video tells a twisted tale of her final hours.

A romantic and scenic early morning boat ride turns deadly when Larry Isenberg falls overboard; investigators reveal the disappearance of half a million dollars, which could be motive for murder.

Twenty-four-year-old Alex Woodworth is brutally stabbed 16 times and left for dead hanging halfway out of the killer's car; as investigators peel back the layers, it's revealed the killer's many lovers is motive for murder.

When an English couple go missing, police suspect their son killed them and must rely on mud and blood samples found in the couple's two cars to find their bodies.

Experts attempt to discover the source of heavy fog on Highway I-75 in Tennessee, which caused a 99-car accident and 12 deaths.

When a woman goes missing from her home, police focus on her husband when an airline luggage tag and luminol point to an affair and murder; footage from a TV crew and Coast Guard photographs lead investigators to the suspect's missing boat.

When a woman exhibits strange flu-like symptoms before dying, investigators discover someone added thallium to her soda; detectives initially suspect her husband, but the case takes a sinister turn.

Handwriting and simple doodles complicate a car-bomb case and an alleged self-defense shooting in a peaceful British farming village as police uncover a husband's plot to kill his wife for insurance money.

When dozens of infants develop serious breathing problems in the Cleveland area, doctors and investigators search high and low for the cause.

A well-liked bank vice president collapses and dies after taking pain pills laced with cyanide; the search for a motive reveals a callous suspect who had murdered once before.

Evidence reveals a teacher who complained of being stalked and harassed by another teacher was scamming police.

A man kills two people with bombs in an effort to get investors off his back, but authorities catch onto him and he becomes sentenced to life with no chance of parole.

A man arrested for the sexual assault and attempted murder of a boy in a European country becomes linked to a murder in Zurich, Switzerland, through analysis of microorganisms.

Heavy rains and snow run-off carry manure into Milwaukee's water supply in 1993, leading to an epidemic of gastrointestinal illness affecting 400,000 people.

Autopsies reveal that a string of unexplained deaths in Omaha resulted from poison-induced liver disintegration.

In a series of murders near Sacramento, Calif., a killer gags and molests prostitutes, cuts their clothes in random patterns and cuts off their hair; microscopic evidence helps solve the case.

After the discovery of a skull in the forest near a boy scout camp, police use facial reconstruction to identify the body.

Investigators use obscure evidence to find the person responsible for killing justice officials with mail bombs in the South.

Forensic scientists provide authorities with evidence that a death deemed accidental 20 years ago was actually murder.

When a woman goes missing from her home, police focus on her husband when an airline luggage tag and luminol point to an affair and murder; footage from a TV crew and Coast Guard photographs lead investigators to the suspect's missing boat.

When a woman exhibits strange flu-like symptoms before dying, investigators discover someone added thallium to her soda; detectives initially suspect her husband, but the case takes a sinister turn.

Handwriting and simple doodles complicate a car-bomb case and an alleged self-defense shooting in a peaceful British farming village as police uncover a husband's plot to kill his wife for insurance money.

When dozens of infants develop serious breathing problems in the Cleveland area, doctors and investigators search high and low for the cause.

A well-liked bank vice president collapses and dies after taking pain pills laced with cyanide; the search for a motive reveals a callous suspect who had murdered once before.

Evidence reveals a teacher who complained of being stalked and harassed by another teacher was scamming police.

A man kills two people with bombs in an effort to get investors off his back, but authorities catch onto him and he becomes sentenced to life with no chance of parole.

A man arrested for the sexual assault and attempted murder of a boy in a European country becomes linked to a murder in Zurich, Switzerland, through analysis of microorganisms.

Heavy rains and snow run-off carry manure into Milwaukee's water supply in 1993, leading to an epidemic of gastrointestinal illness affecting 400,000 people.

Autopsies reveal that a string of unexplained deaths in Omaha resulted from poison-induced liver disintegration.

In a series of murders near Sacramento, Calif., a killer gags and molests prostitutes, cuts their clothes in random patterns and cuts off their hair; microscopic evidence helps solve the case.

After the discovery of a skull in the forest near a boy scout camp, police use facial reconstruction to identify the body.

Investigators use obscure evidence to find the person responsible for killing justice officials with mail bombs in the South.

Forensic scientists provide authorities with evidence that a death deemed accidental 20 years ago was actually murder.

When an 18-year-old girl is abducted while talking on a pay phone, forensic evidence found on her clothing points police in the direction of a suspect who shockingly confesses that he didn't act alone.

In the story of a Los Angeles kidnapping, ransom and murder ring, retired scientists use sonar equipment to locate victims at the bottom of a reservoir.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

For nearly two decades, physician-turned-murderer Michael Swango leaves a trail of death and mayhem across two continents.

Dr. Michael Swango takes an oath to do no harm, but does just the opposite; suspicious illnesses and deaths follow the once-trusted physician-turned-killer from hospital to hospital for nearly two decades and across two continents.

After a 40-year manhunt, investigators finally unmask the man suspected of being California's most prolific serial killer.

Law enforcement personnel identify the Golden State Killer as being Joseph DeAngelo who was hiding in plain sight.

One of the most prolific rapists and serial killers in Alaska's history; for more than a decade, The Butcher Baker kidnapped young women and brought them into the wilderness and hunted them like prey.

For years, The Butcher Baker serial killer was hiding in plain sight; he presented himself as a soft-spoken family man; one woman's story leads police to a shocking discovery inside Robert Hansen's home.

Detectives learn that a genetic disorder caused the deaths of a woman's children, resulting in an overturned conviction.

When a young woman goes missing on the way to the train station, investigators use a strand of hair and a bloody pillowcase to find a suspect.

Investigators reopen a case from 1984 involving the rape of a young Virginia woman when DNA testing refutes her identification of the rapist and calls everything into question, leading to the accused person's exoneration.

A speck of bicycle paint and a speck of nickel left over from a collision with a twice-convicted child molester's car provide critical clues in the murder of a 9-year-old.

A 2-year-old boy's brain seizures and breathing problems baffle doctors until they learn the mother exhibits signs of Munchausen syndrome by proxy, a rare condition that led her to physically abuse her son and contributed to her daughter's death.

Two years after an 18-year-old's murder in Albion, Mich., a tiny drop of blood and burned bones lead police to her killers.

A mother claims that an intruder murdered her two sons, but lacking a motive, police use blood-spatter analysis and behavioral profiling to reconstruct a different scenario.

A routine missing persons report leads Texas police to discover a deadly love triangle; evidence found in a suspect's home matches the murder scene and leads to the indictment of the victim's girlfriend and her lover.

A 1995 fire razes the mansion of a Kansas doctor, killing two of her three children; disturbing accounts from an ex-husband lead investigators to believe the doctor set the blaze herself.

A husband confesses to his wife's murder, only to be found not guilty a year later when a phone tip and forensic evidence point to another.

In Lorton, Va., police attempt to determine who abducted 5-year-old Melissa Brannen after she disappears from a Christmas party, but cannot be certain until they match hair from a rabbit-fur jacket Brannen wore that day.

When a Pennsylvania man checks into a hospital for leg pain and later dies of thallium poisoning, police investigate his wife and find her in the process of collecting an insurance payment for her previous husband's death.

Police exhume the body of Karla Brown, murdered in her home in 1978, to study bite wounds, which eventually lead to the killer.

A new life-insurance policy sparks suspicions of murder when a Nova Scotia schoolteacher's body is found at the bottom of her basement stairs.

Detectives learn that a genetic disorder caused the deaths of a woman's children, resulting in an overturned conviction.

When a young woman goes missing on the way to the train station, investigators use a strand of hair and a bloody pillowcase to find a suspect.

Investigators reopen a case from 1984 involving the rape of a young Virginia woman when DNA testing refutes her identification of the rapist and calls everything into question, leading to the accused person's exoneration.

A speck of bicycle paint and a speck of nickel left over from a collision with a twice-convicted child molester's car provide critical clues in the murder of a 9-year-old.

A 2-year-old boy's brain seizures and breathing problems baffle doctors until they learn the mother exhibits signs of Munchausen syndrome by proxy, a rare condition that led her to physically abuse her son and contributed to her daughter's death.

Two years after an 18-year-old's murder in Albion, Mich., a tiny drop of blood and burned bones lead police to her killers.

A mother claims that an intruder murdered her two sons, but lacking a motive, police use blood-spatter analysis and behavioral profiling to reconstruct a different scenario.

A routine missing persons report leads Texas police to discover a deadly love triangle; evidence found in a suspect's home matches the murder scene and leads to the indictment of the victim's girlfriend and her lover.

A 1995 fire razes the mansion of a Kansas doctor, killing two of her three children; disturbing accounts from an ex-husband lead investigators to believe the doctor set the blaze herself.

A husband confesses to his wife's murder, only to be found not guilty a year later when a phone tip and forensic evidence point to another.

In Lorton, Va., police attempt to determine who abducted 5-year-old Melissa Brannen after she disappears from a Christmas party, but cannot be certain until they match hair from a rabbit-fur jacket Brannen wore that day.

When a Pennsylvania man checks into a hospital for leg pain and later dies of thallium poisoning, police investigate his wife and find her in the process of collecting an insurance payment for her previous husband's death.

Police exhume the body of Karla Brown, murdered in her home in 1978, to study bite wounds, which eventually lead to the killer.

A new life-insurance policy sparks suspicions of murder when a Nova Scotia schoolteacher's body is found at the bottom of her basement stairs.

Patients at the VA Hospital in Clarksburg, W.Va., keep dying after experiencing shockingly low blood sugar levels; an investigation into their deaths reveals an overnight nurse was injecting patients with lethal doses of insulin.

A 70-year-old retired veteran is found dead on his boat after a bad sea storm; detectives discover he was killed during an attempted robbery after winning $400 in keno.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

The anchors share the latest stories about significant events that take place across the world and interview prominent figures.

Police use the little evidence they have to catch the killer of a woman found murdered in her driveway.

Police finally get a break in a case 26 years after the woman was murdered.

A double homicide hits a small town and DNA proves the killer lives among them.

A young Wisconsin woman's body is found and the town is in shock; police look to a cell phone and video to help solve the case.

The murder of Beth Grosskopf leaves her Pennsylvania town full of fear, especially when the initial suspects in the case do not pan out.

After a night out in Maine, a young woman vanishes; no body is found, but a discovery proves murder.

A beverage company pleads guilty to violating federal safety laws when a baby dies from E. coli after drinking apple juice.

A woman who survived a deadly childhood fire sends police a letter charging that her father killed her mother 30 years ago.

After more than 20 people on a Native American reservation die suddenly from a flu-like disease, Navajo medicine men provide a clue that leads to a most unlikely killer.

While at a real estate conference in St. Louis, a man finds his wife drowned in the bathtub in their hotel room.

A cunning serial rapist who leaves no decisive evidence forces investigators to rely on geographical profiling in their search for an identity; DNA from a cigarette butt may provide the final piece of evidence needed to catch the suspect.

New evidence including fibers and weather patterns point to a different killer in the 1986 case of a Pennsylvania dentist's murdered wife.